Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

Garcia-Alloza, Monica, Robbins, Elissa M., Zhang-Nunes, Sandy X., Purcell, Susan M., Betensky, Rebecca A., Raju, Susan, Prada, Claudia, Greenberg, Steven M. +2 more·2006·Neurobiology of Disease
DOI 10.1016/j.nbd.2006.08.017

Cited by (748)

Items 501–600 of 748

  1. Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer’s Disease
    Eva Kiss, S. Kins, Karin Gorgas, Kinga Hajnal Venczel Szakács, Joachim Kirsch, J. Kuhse · 2024 · International Journal of Molecular Sciences
  2. Early life stress amplifies fear responses and hippocampal synaptic potentiation in the APPswe/PS1dE9 Alzheimer mouse model
    Sylvie L. Lesuis, Paul John Lucassen, Harm J. Krugers · 2019 · Neuroscience
  3. Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer’s disease mice
    Adele Woodhouse, Carmen María Fernández-Martos, Rachel A.K. Atkinson, Kelsey Hanson, Jessica Marie Collins, Aidan O'Mara, N Terblanche, M. W. Skinner, James Clement Vickers, Anna Elizabeth King · 2018 · BMC Anesthesiology
  4. Insulin-Like Growth Factor-1 Alleviates Expression of Aβ1–40 and α-, β-, and γ-Secretases in the Cortex and Hippocampus of APP/PS1 Double Transgenic Mice
    Fangfang Song, Tingting Liu, Songyan Meng, Fengqing Li, Yina Zhang, Lihong Jiang · 2018 · Journal of Molecular Neuroscience
  5. Effect of genotype and age on cerebral [18F]FDG uptake varies between transgenic APPSwe-PS1dE9 and Tg2576 mouse models of Alzheimer’s disease
    Anniina Snellman, Jatta S. Helin, Francisco R. Lopez‐Picon, Olli Eskola, Olof H. Solin, Juha O. Rinne, Merja Haaparanta‐Solin · 2019 · Scientific Reports
  6. Repeated performance of spatial memory tasks ameliorates cognitive decline in APP/PS1 mice
    Niklas Lonnemann, Martin Körte, Shirin Hosseini · 2022 · Behavioural Brain Research
  7. Z-Guggulsterone attenuates cognitive defects and decreases neuroinflammation in APPswe/PS1dE9 mice through inhibiting the TLR4 signaling pathway
    Liu, Jing, Lin, Ye, Yang, Yang, Guo, Yane, Shang, Yanchang, Zhou, Bo, Liu, Tianlong, Fan, Jiao, Wei, Chao · 2022 · Biochemical Pharmacology
  8. Apicidin attenuates memory deficits by reducing the Aβ load in APP / PS1 mice
    Biao Luo, Jian Chen, Gui‐Feng Zhou, Xiao‐Yong Xie, Jing Tang, Qi‐Xin Wen, Song Li, Shi‐Qi Xie, Yan Long, Guojun Chen et al. · 2023 · CNS Neuroscience & Therapeutics
  9. Evolution of Alzheimer’s Disease Therapeutics: From Conventional Drugs to Medicinal Plants, Immunotherapy, Microbiotherapy and Nanotherapy
    Emma Ortiz-Islas, Pedro Montes, Citlali Ekaterina Rodríguez-Pérez, Elizabeth Ruiz-Sánchez, Talía Sánchez-Barbosa, Diego Pichardo-Rojas, Cecilia Zavala‐Tecuapetla, Karla Carvajal, Victoria Campos‐Peña · 2025 · Pharmaceutics
  10. Cattle encephalon glycoside and ignotin injection improves cognitive impairment in APPswe/PS1dE9 mice used as multitarget anti-Alzheimer’s drug candidates
    Luning Wang, Ya Gao, Yazhuo Hu, Ruisheng Li, Zhitao Han, Yan Geng, Zheng Xia, Lixin Liu, Wenjin Du, Honghong Zhang · 2015 · Neuropsychiatric Disease and Treatment
  11. Dexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer’s disease in metabolically stressed APPswe/PS1dE9 mice
    Miren Ettcheto, Elena Sánchez‐López, Amanda C. Cano, Marina Carrasco, Katherine Herrera, Patrícia Regina Manzine, Triana Espinosa-Jiménez, Oriol Busquets, Ester Verdaguer, Jordi Olloquequi et al. · 2021 · Cell & Bioscience
  12. Deficits in Aversive but not in Safe Taste Memory in the APPswe/PS1dE9 mice
    Leticia Ramı́rez-Lugo, Morten S. Jensen, Andreas Søderman, Mark J. West · 2009 · Journal of Alzheimer s Disease
  13. Early detection of redox imbalance in the APPswe/PS1dE9 mouse model of Alzheimer’s disease by in vivo electron paramagnetic resonance imaging
    Miho C. Emoto, Hideo Sato‐Akaba, Naoya Hamaue, Katsuya Kawanishi, Hisashi Koshino, Shun Shimohama, Hirotada G. Fujii · 2021 · Free Radical Biology and Medicine
  14. Hippocampal sub-networks exhibit distinct spatial representation deficits in Alzheimer’s disease model mice
    Ohad Rechnitz, Inna Slutsky, Genela Morris, Dori Derdikman · 2021 · Current Biology
  15. Outstanding Phenotypic Differences in the Profile of Amyloid-β between Tg2576 and APPswe/PS1dE9 Transgenic Mouse Models of Alzheimer’s Disease
    José Antonio Allué, Leticia Sarasa, María Izco, Virginia Pérez‐Grijalba, Noelia Fandos, María Pascual‐Lucas, Samuel Ogueta, Pedro Pesini, Manuel Sarasa · 2016 · Journal of Alzheimer s Disease
  16. Paradoxical effects of mutant ubiquitin on Aβ plaque formation in an Alzheimer mouse model
    Bert M. Verheijen, Jo Stevens, Romina J. G. Gentier, Christian D. van ‘t Hekke, Daniël van den Hove, Denise J. H. P. Hermes, Harry W.M. Steinbusch, Jan M. Ruijter, Marcus O.W. Grimm, Viola J. Haupenthal et al. · 2018 · Neurobiology of Aging
  17. “Dual Disease” TgAD/GSS mice exhibit enhanced Alzheimer’s disease pathology and reveal PrPC-dependent secretion of Aβ
    Kefeng Qin, Lili Zhao, Crystal Gregory, Ani Solanki, James A. Mastrianni · 2019 · Scientific Reports
  18. Amyloid‐related imaging abnormalities (ARIA) in anti‐amyloid therapies for Alzheimer's disease: An update from the Alzheimer's Association ARIA workgroup
    Ellis S. van Etten, Simin Mahinrad, Joshua D. Grill, Stephen Salloway, Alireza Atri, Petrice M. Cogswell, Tammie L.S. Benzinger, Takeshi Iwatsubo, Costantino Iadecola, Cynthia Ann Lemere et al. · 2026 · Alzheimer s & Dementia
  19. Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ pathology
    Rocío Alfaro‐Ruiz, Alejandro Martín‐Belmonte, Carolina Aguado, Ana Esther Moreno‐Martínez, Yugo Fukazawa, Rafael Luján · 2024 · Biological Research
  20. A promising drug repurposing approach for Alzheimer's treatment: Givinostat improves cognitive behavior and pathological features in APP/PS1 mice
    Qi-Chao Gao, Ge-Liang Liu, Qi Wang, Sheng‐Xiao Zhang, Zhang Ji, Zhao‐Jun Wang, Meina Wu, Qi Yu, P. F. He · 2024 · Redox Biology
  21. Gut Microbiota-Driven Metabolic Alterations Reveal the Gut-Brain Communication of Ergothioneine in Ameliorating Cognitive Impairment in APP/PS1 Mice
    Na Li, Shan Wang, Hongbo Li, Zhenbin Liu, Haizhen Mo, Jing Luan, Na Guo, Xingchun Gou, Yue Wu, Zhuo Li · 2025 · Journal of Agricultural and Food Chemistry
  22. Regional differences in beta amyloid plaque deposition and variable response to midlife environmental enrichment in the cortex of APP/PS1 mice
    B. Fulopova, K. Stuart, W. Bennett, A. Bindoff, A. King, J. Vickers, A. Canty · 2020 · The Journal of comparative neurology
  23. Imaging asparaginyl endopeptidase (AEP) in the live brain as a biomarker for Alzheimer’s disease
    Shanshan Wang, Zikai Liu, Jingjing Liu, Qing Cheng, Yanxia Wang, Yan Liu, Wen-Wen Ni, Hongzhuan Chen, Mingke Song · 2021 · Journal of Nanobiotechnology
  24. Treadmill Exercise Promotes Microglial β-Amyloid Clearance and Prevents Cognitive Decline in APP/PS1 Mice
    Fei Liang, Feng Sun, Biao He, Jing Wang · 2022 · Neuroscience
  25. Prophylactic Vaccine Based on Pyroglutamate-3 Amyloid β Generates Strong Antibody Response and Rescues Cognitive Decline in Alzheimer’s Disease Model Mice
    Li Gao, Zhiwen Hu, Pu‐Guang Chen, Zhanyi Sun, Yong‐Xiang Chen, Yufen Zhao, Yanmei Li · 2016 · ACS Chemical Neuroscience
  26. Different effects of anesthetic isoflurane on caspase-3 activation and cytosol cytochrome c levels between mice neural progenitor cells and neurons
    Yiying Zhang, Chuxiong Pan, Xu Wu, Yuanlin Dong, Deborah J. Culley, Gregory J. Crosby, Tianzuo Li, Zhongcong Xie · 2014 · Frontiers in Cellular Neuroscience
  27. Cholinergic Basal Forebrain Lesion Decreases Neurotrophin Signaling without Affecting Tau Hyperphosphorylation in Genetically Susceptible Mice
    Marion T. Turnbull, Elizabeth Jane Coulson · 2016 · Journal of Alzheimer s Disease
  28. Characterization of an ‘Amyloid Only’ Transgenic (B6C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax) Mouse Model of Alzheimer's Disease
    G.S. Finnie, Ronny Kent Gunnarsson, Jim Manavis, Peter Charles Blumbergs, K.A. Mander, Stephen R. Edwards, Cameron J. van den Heuvel, John W Finnie · 2017 · Journal of Comparative Pathology
  29. Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice
    Xin Wang, Wei Wu, Guang Yang, Xuewei Yang, Xu Ma, Dandan Zhu, Kabir Ahmad, Khizar Khan, Yingzi Wang, Ao‐Ran Sui et al. · 2024 · Journal of Advanced Research
  30. Lead Acetate Exposure and Cerebral Amyloid Accumulation: Mechanistic Evaluations in APP/PS1 Mice
    Huiying Gu, Luqing L. Liu, Alanna Wu, Yongqi Yu, Uzay E. Emir, Stephen J. Sawiak, Paul R. Territo, Martin Rhys Farlow, Wei Zheng, Yansheng Du · 2024 · Environmental Health Perspectives
  31. Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease
    Allison Carles, Aline Freyssin, Sarra Guehairia, Thomas Reguero, Michel Vignes, Hélène Hirbec, Gilles Rubinstenn, Tangui Maurice · 2025 · Alzheimer s Research & Therapy
  32. Reducing Available Soluble β-Amyloid Prevents Progression of Cerebral Amyloid Angiopathy in Transgenic Mice
    Julia L. Gregory, Claudia M. Prada, Sara Fine, Mónica Garcı́a-Alloza, Rebecca A. Betensky, Michal Arbel‐Ornath, Steven Mark Greenberg, Brian J. Bacskai, Matthew P. Frosch · 2012 · Journal of Neuropathology & Experimental Neurology
  33. Trans ε-Viniferin Decreases Amyloid Deposits With Greater Efficiency Than Resveratrol in an Alzheimer’s Mouse Model
    Aline Freyssin, Agnès Rioux Bilan, Bernard Fauconneau, Laurent Galineau, Sophie Sérrière, Clovis Tauber, Flavie Perrin, Jérôme Guillard, Sylvie Chalon, Guylène Page · 2022 · Frontiers in Neuroscience
  34. Impact of chronic doxycycline treatment in the APP/PS1 mouse model of Alzheimer's disease
    Victoria Gómez‐Murcia, Kévin Carvalho, Bryan Thiroux, Raphaëlle Caillierez, Mélanie Besegher, Nicolas Sergeant, Luc Buée, E Faivre, David L Blum · 2022 · Neuropharmacology
  35. Linking Social Cognition, Parvalbumin Interneurons, and Oxytocin in Alzheimer’s Disease: An Update
    Daniela Černotová, Karolína Hrůzová, David Levčík, Jan Svoboda, Aleš Stuchlı́k · 2023 · Journal of Alzheimer s Disease
  36. Beta Amyloid Peptides: Extracellular and Intracellular Mechanisms of Clearance in Alzheimer’s Disease
    Luis Fernando Hernández-Zimbrón, Elisa Gorostieta-Salas, Mei-Li Díaz-Hung, Roxanna Pérez-Garmendia, Gohar Gevorkian, Hugo Quiroz-Mercado · 2016 · InTech eBooks
  37. Dynamic SAP 102 expression in the hippocampal subregions of rats and APP / PS 1 mice of various ages
    Dongning Su, Hui Liu, Tianrong Liu, Xin Zhang, Wei Yang, Yizhi Song, Jinping Liu, Yan Wu, Lirong Chang · 2018 · Journal of Anatomy
  38. Neuroprotective effects of novel compound FMDB on cognition, neurogenesis and apoptosis in APP/PS1 transgenic mouse model of Alzheimer's disease
    Xiaoqian Ren, Xin Huang, Shu-Yun Xing, Yan Long, Dan-Hua Yuan, Hao Hong, Susu Tang · 2023 · Neurochemistry International
  39. Deficits in hippocampal‐dependent transfer generalization learning accompany synaptic dysfunction in a mouse model of amyloidosis
    Karienn S. Montgomery, George A. Edwards, Yona Levites, Ashok Kumar, Catherine E. Myers, Mark A. Gluck, Barry Setlow, Jennifer L. Bizon · 2015 · Hippocampus
  40. Four-dimensional microglia response to anti-Aβ treatment in APP/PS1xCX3CR1/GFP mice
    Mónica Garcı́a-Alloza, Laura A. Borrelli, Diana H. Thyssen, Suzanne E. Hickman, Joseph B. El Khoury, Brian J. Bacskai · 2013 · IntraVital
  41. Adolescent exposure to MDMA induces dopaminergic toxicity in substantia nigra and potentiates the amyloid plaque deposition in the striatum of APPswe/PS1dE9 mice
    Sònia Abad, Carla Ramon‐Duaso, David Pubill, Jorge Camarasa, Antoni Camins, Elena Escubedo · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  42. Transcranial in vivo detection of amyloid-beta at single plaque resolution with large-field multifocal illumination fluorescence microscopy
    Ruiqing Ni, Zhenyue Chen, Gloria Shi, Alessia Villois, Quanyu Zhou, Paolo Arosio, Roger M. Nitsch, K. Peter R. Nilsson, Jan Klohs, Daniel Razansky · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  43. Nanoarchitecture of CaV2.1 channels and GABAB receptors in the mouse hippocampus: Impact of APP/PS1 pathology
    Alejandro Martín‐Belmonte, Carolina Aguado, Rocío Alfaro‐Ruiz, Ákos Kulik, Luis de la Ossa, Ana Esther Moreno‐Martínez, Samuel Alberquilla, Lucía García‐Carracedo, Miriam Fernández, Ana Fajardo‐Serrano et al. · 2024 · Brain Pathology
  44. Social isolation impairs cognition via Aβ-mediated synaptic dysfunction
    Fang Huang, Xinghua Liu, Qian Guo, Yacoubou Abdoul Razak Mahaman, Bin Zhang, Jian‐Zhi Wang, Hongbin Luo, Rong Liu, Xiaochuan Wang · 2024 · Translational Psychiatry
  45. Divergent brain solute clearance in rat models of cerebral amyloid angiopathy and Alzheimer’s disease
    Sunil Koundal, Xinan Chen, Zachary H. Gursky, Hedok Lee, Kaiming Xu, Feng Liang, Zhongcong Xie, Feng Xu, Hung‐Mo Lin, William E. Van Nostrand et al. · 2024 · iScience
  46. Intraperitoneal Administration of Monoclonal Antibody Against Pathologic Aβ 42 Aggregates Alleviated Cognitive Deficits and Synaptic Lesions in APP/PS1 Mice
    Shuo Xiao, Linlin Song, Jiangtao Li, He Wang, Na Yu, Ziqi Wang, Ying Zhang, Jinsheng He, Tao Hung · 2019 · Journal of Alzheimer s Disease
  47. Enhanced Anti-Amyloid Effect of Combined Leptin and Pioglitazone in APP/PS1 Transgenic Mice
    Yao Liu, Kelsey Hanson, Graeme H. McCormack, Rachel A.K. Atkinson, Justin Dittmann, James Clement Vickers, Carmen María Fernández-Martos, Anna Elizabeth King · 2021 · Current Alzheimer Research
  48. Recommendations for Preclinical Testing of Treatments Against Alzheimer’s Disease-Related Epileptiform Spikes in Transgenic Rodent Models
    Nanxiang Jin, Claudio Babiloni, Wilhelmus H. I. M. Drinkenburg, Mihály Hajós, Haakon B. Nygaard, Heikki Tanila · 2021 · Journal of Alzheimer s Disease
  49. Lipocalin‐Type Prostaglandin d Synthase Conjugates as Magnetic Resonance Imaging Contrast Agents for Detecting Amyloid β‐Rich Regions in the Brain of Live Alzheimer's Disease Mice
    Bhargy Sharma, Joanes Grandjean, Margaret Phillips, Ambrish Kumar, Francesca Mandino, Ling Yun Yeow, Kimberly Jia Yi Low, Vikas Nandwana, Vinayak P. Dravid, Bengang Xing et al. · 2021 · Advanced NanoBiomed Research
  50. Effects of diverse Types of Toxoplasma gondii on the outcome of Alzheimer's disease in the rat model
    Tahereh Mikaeili Galeh, Hamed Ghazvini, Moslem Mohammadi, Shahabeddin Sarvi, Soheil Azizi, Hossein Asgarian‐Omran, Fatemeh Hajizadeh, Ahmad Daryani · 2022 · Microbial Pathogenesis
  51. Motor Cortex Theta and Gamma Architecture in Young Adult APPswePS1dE9 Alzheimer Mice
    Anna Papazoglou, Julien Soós, Andreas Lundt, Carola Wormuth, Varun Raj Ginde, Ralf Müller, Christina Henseler, Karl Broich, Kan Xie, Britta Haenisch et al. · 2017 · PLoS ONE
  52. Heat Shock Proteins and Protein Quality Control in Alzheimer’s Disease
    Fred W. van Leeuwen, Harm H. Kampinga · 2018 · Elsevier eBooks
  53. The influence of GAPT extraction on synapse loss of APPswe/PS1dE9 transgenic mice via adjusting Bcl‐2/Bax balance
    Jing Shi, Xuekai Zhang, Jingnian Ni, Mingqing Wei, Ting Li, Bingling Zhou, Xiawei Liu, Liping Zhang, Pengwen Wang, Jinzhou Tian et al. · 2018 · Alzheimer s & Dementia Translational Research & Clinical Interventions
  54. Age-related disturbances in DNA (hydroxy)methylation in APP/PS1 mice
    Leonidas Chouliaras, Roy Lardenoije, Günter Kenis, Diego Mastroeni, Patrick R. Hof, Jim van Os, Harry W.M. Steinbusch, Fred W. van Leeuwen, Bart P. F. Rutten, Daniël van den Hove · 2018 · Translational Neuroscience
  55. Gamma sensory stimulation and effects on the brain
    Martin C. Kahn, Diane Chan, Danying Wang, Ute Geigenmüller, Cristina Blanco‐Duque, Mitchell H. Murdock, Ho‐Jun Suk, Brennan Jackson, Vikram Jakkamsetti, Emily D. Niederst et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  56. Transmissible long-term neuroprotective and pro-cognitive effects of 1–42 beta-amyloid with A2T icelandic mutation in an Alzheimer’s disease mouse model
    Marina Célestine, Muriel R. Jacquier‐Sarlin, Eve Borel, Fanny Petit, Fabien Lanté, Luc Bousset, Anne‐Sophie Hérard, Alain Buisson, Marc Dhénain · 2024 · Molecular Psychiatry
  57. Time or place? Dissociation between object-in-place and relative recency in young APPswe/PS1dE9 mice.
    Charlotte Bonardi, Marie‐Christine Pardon, Paul Armstrong · 2021 · Behavioral Neuroscience
  58. Herpes Simplex Virus 1 Infection Does Not Increase Amyloid-β Pathology in APP/PS1 Mice
    Lina Lapeyre, Jocelyne Piret, Chantal Rhéaume, Vincent Pons, Olus Uyar, Paul Préfontaine, Serge Rivest, Guy Boivin · 2023 · Journal of Alzheimer s Disease
  59. Herbal Extracts Combination (WNK) Prevents Decline in Spatial Learning and Memory in APP/PS1 Mice through Improvement of Hippocampal AβPlaque Formation, Histopathology, and Ultrastructure
    Weihong Cong, Bin Yang, Xu Li, Xiao-Xia Dong, Li-Song Sheng, Jin-cai Hou, Jianxun Liu · 2012 · Evidence-based Complementary and Alternative Medicine
  60. Development of Gleevec Analogues for Reducing Production of β-Amyloid Peptides through Shifting β-Cleavage of Amyloid Precursor Proteins
    Weilin Sun, William J. Netzer, Anjana Sinha, Katherina Gindinova, Emily Chang, Subhash C. Sinha · 2019 · Journal of Medicinal Chemistry
  61. Timing impairments in early Alzheimer's disease: Evidence from a mouse model.
    Paul Armstrong, Marie-Christine Pardon, C. Bonardi · 2020 · Behavioral Neuroscience
  62. SRC-1 Knockout Exerts No Effect on Amyloid β Deposition in APP/PS1 Mice
    Qiong Wu, Bin Wang, Qifa Li, Xuan Zhang, Michael Ntim, Xuefei Wu, Na Li, Dandan Zhu, Rong Jiang, Jin-Yi Yang et al. · 2020 · Frontiers in Aging Neuroscience
  63. Amyloid Plaques Show Binding Capacity of Exogenous Injected Amyloid-β
    Irina Gureviciene, Kestutis Gurevicius, Ekaterina Mugantseva, Mikhail Kislin, Leonard S. Khiroug, Heikki Tanila · 2016 · Journal of Alzheimer s Disease
  64. A PDK-1 Allosteric Agonist Improves Spatial Learning and Memory in a ΒAPP/PS-1 Transgenic Mouse-High Fat Diet Intervention Model of Alzheimer's Disease
    Henry W. Querfurth, Angela Lucas Slitt, Amy DiCamillo, Nathan O. Surles, Brenton DeBoef, Hankyu Lee · 2022 · SSRN Electronic Journal
  65. 3,6′-Disinapoyl sucrose alleviates cognitive deficits in APP/PS1 transgenic mice
    Jiaqi Yuan, Mengjie He, Xueling Dai, Qing Huo, Ping Chang, Jing Zhang, Shuo Wang, Yaxuan Sun · 2023 · Journal of Neurophysiology
  66. Brain Amyloidosis and BDNF Deficiency Have Opposite Effects on Brain Volumes in AβPP/PS1 Mice Both in vivo and ex vivo
    Elisa Kärkkäinen, Hanna-Maija Lahtinen, Johanna Närväinen, Olli H.J. Gröhn, Heikki Tanila · 2015 · Journal of Alzheimer s Disease
  67. Timing behavior in genetic murine models of neurological and psychiatric diseases
    Ayşe Karson, Fuat Balcı · 2021 · Experimental Brain Research
  68. A Polyaminobiaryl-Based β-secretase Modulator Alleviates Cognitive Impairments, Amyloid Load, Astrogliosis, and Neuroinflammation in APPSwe/PSEN1ΔE9 Mice Model of Amyloid Pathology
    Marie Tautou, Florian Descamps, Paul-Emmanuel Larchanché, Luc Buée, Jamal El Bakali, Patricia Melnyk, Nicolas Sergeant · 2023 · International Journal of Molecular Sciences
  69. An Overview of Transgenic Mouse Models for the Study of Alzheimer’s Disease
    Paula A. Lopes, Mafalda Soares Pádua, José Luis Guil‐Guerrero · 2025 · Journal of dementia and Alzheimer's disease
  70. Differential Detection of Amyloid Aggregates in Old Animals Using Gold Nanorods by Computerized Tomography: A Pharmacokinetic and Bioaccumulation Study
    Pedro Jara-Guajardo, Francisco Morales-Zavala, Karen Bolaños, Ernest Giralt, Eyleen Araya, Gerardo Acosta, Fernando Alberício, Alejandra R. Alvarez, Marcelo Javier Kogan · 2023 · International Journal of Nanomedicine
  71. Long term worsening of amyloid pathology, cerebral function, and cognition after a single inoculation of beta-amyloid seeds with Osaka mutation
    Marina Célestine, Muriel R. Jacquier‐Sarlin, Eve Borel, Fanny Petit, J. Pérot, Anne‐Sophie Hérard, Luc Bousset, Alain Buisson, Marc Dhénain · 2023 · Acta Neuropathologica Communications
  72. Selective Peripheral Taste Dysfunction in APP/PS1 Mutant Transgenic Mice
    Ryan M. Wood, Zacnite Garcia, Nathan Daniels, Shannon M. Landon, Saima Humayun, Hyoung‐gon Lee, Lindsey J. Macpherson · 2020 · Journal of Alzheimer s Disease
  73. Novel Botanical Therapeutic NB-02 Effectively Treats Alzheimer’s Neuropathophysiology in an APP/PS1 Mouse Model
    Yee Fun Lee, Lavender Lariviere, Alyssa Russ, Sang‐Zin Choi, Brian J. Bacskai, Ksenia V. Kastanenka · 2021 · eNeuro
  74. Amylin Pharmacology in Alzheimer’s Disease Pathogenesis and Treatment
    Gemma Casadesus, Rachel R. Corrigan, Helen Piontkivska · 2021 · Current Neuropharmacology
  75. Delayed amyloid plaque deposition and behavioral deficits in outcrossed AβPP/PS1 mice
    Brian A. Couch, Meghan E. Kerrisk, Adam C. Kaufman, Haakon B. Nygaard, Stephen M. Strittmatter, Anthony J. Koleske · 2012 · The Journal of Comparative Neurology
  76. Impaired hippocampal circuit function underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of alzheimer’s disease
    Hanyan Li, Zhuoyang Zhao, Aline Fassini, Han K. Lee, Reese J. Green, Stephen N. Gomperts · 2025 · Scientific Reports
  77. Raw Inonotus obliquus polysaccharide counteracts Alzheimer’s disease in a transgenic mouse model by activating the ubiquitin-proteosome system
    Shumin Wang, Kaiye Dong, Ji Zhang, Chaochao Chen, Hongyan Shuai, Xin Yu · 2023 · Nutrition Research and Practice
  78. Ascorbate insufficiency disrupts glutamatergic signaling and alters electroencephalogram phenotypes in a mouse model of Alzheimer's disease
    Rebecca A. Buchanan, Yuhan Wang, James Michael May, Fiona Edith Harrison · 2024 · Neurobiology of Disease
  79. Longitudinal and Multi-Kingdom Gut Microbiome Alterations in a Mouse Model of Alzheimer’s Disease
    Tao Zhang, Chunyan Zhao, Na Li, Qiuwen He, Guangqi Gao, Zhihong Sun · 2024 · International Journal of Molecular Sciences
  80. Cognition–Eye–Brain Connection in Alzheimer's Disease Spectrum Revealed by Multimodal Imaging
    Yan Shi, Tingting Shen, Su Yan, Jianwen Liang, Tianyunxi Wei, Yijin Huang, Rong Gao, Ning Zheng, Renpuchi Ci, Min Zhang et al. · 2025 · Journal of Magnetic Resonance Imaging
  81. Two novel mouse models of slow-wave-sleep enhancement in aging and Alzheimer’s disease
    Oghomwen E Ogbeide-Latario, Loris L. Ferrari, Heinrich S. Gompf, Christelle Anaclet · 2022 · SLEEP Advances
  82. Alleviation of behavioral deficits, amyloid-β deposition, and mitochondrial structure damage associated with mitophagy upregulation in AD animal models via AAV9-IGF-1 treatment
    Ying Wang, Chaoyuan Song, Guoliang Yin, Meng Ye, Fengxia Zhang · 2023 · Brain Research
  83. Pharmacological inhibition of PLK2 kinase activity mitigates cognitive decline but aggravates APP pathology in a sex-dependent manner in APP/PS1 mouse model of Alzheimer's disease
    Laura Martínez-Drudis, Morgan Bérard, Dylan Musiol, Serge Rivest, Abid Oueslati · 2024 · Heliyon
  84. 14 Amyloid Imaging and (What is “Normal”?) Aging
    William Edward Klunk, Chester A. Mathis · 2009 · Oxford University Press eBooks
  85. Effect of Experimental Ischemic Stroke and PGE2 EP1 Selective Antagonism in Alzheimer’s Disease Mouse Models
    Fúlvio Rieli Mendes, Jenna L Leclerc, Lei Liu, Pradip Kumar Kamat, Arash Naziripour, Damian Hernandez, Chris Li, Abdullah Shafique Ahmad, Sylvain Doré · 2020 · Journal of Alzheimer s Disease
  86. Gene deletion of Pregnancy-associated Plasma Protein-A (PAPP-A) improves pathology and cognition in an Alzheimer's disease mouse model
    Laurie K. Bale, Sally A. West, Naomi M. Gades, Darren J. Baker, Cheryl A. Conover · 2024 · Experimental Neurology
  87. The role of LINGO-1 in regulating CB1R/TrkB signalling and GABAergic interneurons in Alzheimer's disease pathogenesis
    Qi He, Lin Hong Jiang, Feng‐lei Chao, Chunni Zhou, Lei Zhang, Yuning Zhou, Yiying Wang, Yuhui Deng, Jing Tang, Yanmin Luo et al. · 2025 · Experimental Neurology
  88. An intracerebroventricular injection of AΒ (1–42) modifies temporal profiles of spatial memory performance and oxidative status in the temporal cortex rat
    Cinthia Daiana Coria-Lucero, Andrea Castro, Carina Ledezma, Jorge Leporatti, Darío C. Ramírez, Marisa Ghersi, Silvia M. Delgado, Ana Cecilia Anzulovich, Lorena Navigatore-Fonzo · 2023 · Brain Research
  89. Potential Treatment Strategies of Dementia With Ayurvedic Medicines
    A. A. Farooqui · 2019 · Elsevier eBooks
  90. Zero Echo Time 17O-MRI Reveals Decreased Cerebral Metabolic Rate of Oxygen Consumption in a Murine Model of Amyloidosis
    Céline Baligand, Olivier Barret, Amélie Tourais, J. Pérot, Didier Thenadey, Fanny Petit, Géraldine Liot, Marie‐Claude Gaillard, Julien Flament, Marc Dhénain et al. · 2021 · Metabolites
  91. Atrophy of lacunosum moleculare layer is important for learning and memory in APP/PS1 transgenic mice
    Yi Zhang, Feng‐lei Chao, Chunni Zhou, Lin Hong Jiang, Lei Zhang, Xin Liang, Jing Tang, Yong Cheng Tang · 2021 · Neuroreport
  92. Antimuscarinics for the treatment of overactive bladder: A review of central nervous system effects
    Adam P. Klausner, William Donald Steers · 2008 · Current Bladder Dysfunction Reports
  93. Pathological changes induced by Alzheimer’s brain inoculation in amyloid-beta plaque-bearing mice
    Suzanne Lam, Anne‐Sophie Hérard, Susana Boluda, Fanny Petit, Sabiha Eddarkaoui, Karine Cambon, The Brainbank Neuro-CEB Neuropathology Network, Jean‐Luc Picq, Luc Buée, Charles J. Duyckaerts et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  94. Effects of resistance exercise on behavioral and molecular changes in transgenic female mice for Alzheimer's disease in early and advanced stages
    Eduardo Alves da Silva, Jean Faber, Arlete Rita Penitente, Jansen Fernandes, Paulo Henrique Ferreira Bertolucci, Beatriz M. Longo, Ricardo Mário Arida · 2025 · Experimental Neurology
  95. Neuroinflammatory chemokine networks in transgenic models of Alzheimer’s disease: A comparative multi-compartmental analysis
    Yangyan Sun, Xinhua Xie, Xiaoqin Zou, Futao Zhou · 2025 · Human & Experimental Toxicology
  96. Platycodin D Attenuates Behavioral Deficits, Amyloid-β Accumulation and Mitochondrial Impairment in AD Models by Inhibiting the cGAS-STING Pathway
    Chaoyuan Song, Guoliang Yin, Linya Wang, Fengxia Zhang · 2025 · NeuroMolecular Medicine
  97. Multi-omics reveals changes in astrocyte fatty acid metabolism during early stages of Alzheimer's disease
    Zhong, Jie, Li, Manhui, Dai, Ziwei, Wan, Jun · 2025 · Neurochemistry International
  98. Ceftriaxone alleviates mitochondrial damage through the inhibition of extrasynaptic NMDA receptor-mediated changes in intracellular calcium levels to improve cognitive deficits in APP/PS1 mice
    Li-Rong Liu, Li Li, Li-Li Lu, S. Fan, Li-Zhe Liu, Ruo-Bing He, Heng Li, Xiao-Hui Xian, Wenbin Li · 2025 · Alzheimer's Research & Therapy
  99. Age and sex dependent hippocampal neuronal hyperactivity in Alzheimer model mice
    E. Hegnet, Sara Häkli, H. Koivisto, P.O. Miettinen, N. Jin, Irina Gureviciene, Heikki Tanila · 2025 · Experimental Neurology
  100. Intranasal delivery of Odorranalectin-modified lipid nanoparticles for multi-targeted therapy of Alzheimer's disease
    Yumeng Zhang, Changfeng Yin, Yushan Tian, Xiao Li, Hongjuan Wang, Shulei Han, Huan Chen, Hongwei Hou · 2026 · Materials Today Bio