Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

Garcia-Alloza, Monica, Robbins, Elissa M., Zhang-Nunes, Sandy X., Purcell, Susan M., Betensky, Rebecca A., Raju, Susan, Prada, Claudia, Greenberg, Steven M. +2 more·2006·Neurobiology of Disease
DOI 10.1016/j.nbd.2006.08.017

Cited by (748)

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  92. Disturbances in the control of capillary flow in an aged APPswe/PS1ΔE9 model of Alzheimer's disease
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  93. Early administration of galantamine from preplaque phase suppresses oxidative stress and improves cognitive behavior in APPswe/PS1dE9 mouse model of Alzheimer's disease
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  94. Increased Spontaneous Central Bleeding and Cognition Impairment in APP/PS1 Mice with Poorly Controlled Diabetes Mellitus
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  95. Olfactory and Visuospatial Learning and Memory Performance in Two Strains of Alzheimer's Disease Model Mice—A Longitudinal Study
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  96. Traumatic Brain Injury Increases the Expression of Nos1, Aβ Clearance, and Epileptogenesis in APP/PS1 Mouse Model of Alzheimer’s Disease
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  98. Human Neural Stem Cells Encoding ChAT Gene Restore Cognitive Function via Acetylcholine Synthesis, Aβ Elimination, and Neuroregeneration in APPswe/PS1dE9 Mice
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  99. Plaque Deposition Dependent Decrease in 5-HT2A Serotonin Receptor in AβPPswe/PS1dE9 Amyloid Overexpressing Mice
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  100. Distribution of Zn isotopes during Alzheimer’s disease
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