Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease

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5. Early memory deficits precede plaque deposition in APPswe/PS1dE9 mice: Involvement of oxidative stress and cholinergic dysfunction
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7. The role of neuroinflammation and amyloid in cognitive impairment in an APP / PS 1 transgenic mouse model of Alzheimer's disease
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8. Lamotrigine attenuates deficits in synaptic plasticity and accumulation of amyloid plaques in APP/PS1 transgenic mice
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9. IGF2 Ameliorates Amyloidosis, Increases Cholinergic Marker Expression and Raises BMP9 and Neurotrophin Levels in the Hippocampus of the APPswePS1dE9 Alzheimer’s Disease Model Mice
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10. Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease
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11. Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model
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12. Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer’s disease
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16. Blocking the Interaction between Apolipoprotein E and Aβ Reduces Intraneuronal Accumulation of Aβ and Inhibits Synaptic Degeneration
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17. Increased Aβ production prompts the onset of glucose intolerance and insulin resistance
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18. Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease
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19. Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice
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20. NO2 inhalation promotes Alzheimer’s disease-like progression: cyclooxygenase-2-derived prostaglandin E2 modulation and monoacylglycerol lipase inhibition-targeted medication
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21. Alterations in Cerebral Cortical Glucose and Glutamine Metabolism Precedes Amyloid Plaques in the APPswe/PSEN1dE9 Mouse Model of Alzheimer’s Disease
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22. Nicotine Prevents Synaptic Impairment Induced by Amyloid-β Oligomers Through α7-Nicotinic Acetylcholine Receptor Activation
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23. Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice
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24. Non-Fibrillar Oligomeric Amyloid-β within Synapses
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25. Increased Cortical and Thalamic Excitability in Freely Moving APPswe/PS1dE9 Mice Modeling Epileptic Activity Associated with Alzheimer's Disease
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26. <i>Bifidobacterium breve</i> HNXY26M4 Attenuates Cognitive Deficits and Neuroinflammation by Regulating the Gut–Brain Axis in APP/PS1 Mice
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27. Seizure susceptibility in the APP/PS1 mouse model of Alzheimer’s disease and relationship with amyloid β plaques
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28. Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network
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29. Passive Immunization against Pyroglutamate-3 Amyloid-β Reduces Plaque Burden in Alzheimer-Like Transgenic Mice: A Pilot Study
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30. Imaging of cerebrovascular pathology in animal models of Alzheimer's disease
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31. Longitudinal Amyloid Imaging in Mouse Brain with 11C-PIB: Comparison of APP23, Tg2576, and APPswe-PS1dE9 Mouse Models of Alzheimer Disease
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32. Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease
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33. Role of clusterin in the brain vascular clearance of amyloid-β
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34. Anesthetic Isoflurane Increases Phosphorylated Tau Levels Mediated by Caspase Activation and Aβ Generation
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40. Measurements of cerebrospinal fluid production: a review of the limitations and advantages of current methodologies
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41. The problem of genotype and sex differences in life expectancy in transgenic AD mice
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44. Gray and white matter degeneration revealed by diffusion in an Alzheimer mouse model
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46. Long-term treadmill exercise improves spatial memory of male appswe/ps1de9 mice by regulation of bdnf expression and microglia activation
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48. Epigallocatechin-3-Gallate (EGCG) Improves Cognitive Deficits Aggravated by an Obesogenic Diet through Modulation of Unfolded Protein Response in APPswe/PS1dE9 Mice
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49. Chronic Intranasal Treatment with an Anti-Aβ30-42 scFv Antibody Ameliorates Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease
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52. MiR-299-5p regulates apoptosis through autophagy in neurons and ameliorates cognitive capacity in APPswe/PS1dE9 mice
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53. Existing plaques and neuritic abnormalities in APP:PS1 mice are not affected by administration of the gamma-secretase inhibitor LY-411575
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55. Morin reverses neuropathological and cognitive impairments in APPswe/PS1dE9 mice by targeting multiple pathogenic mechanisms
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56. Curcumin derivative with the substitution at C-4 position, but not curcumin, is effective against amyloid pathology in APP/PS1 mice
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57. Reactive astrocytes as treatment targets in Alzheimer's disease—Systematic review of studies using the <scp>APPswePS1dE9</scp> mouse model
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58. Animal models of cerebral amyloid angiopathy
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59. Retinal capillary degeneration and blood-retinal barrier disruption in murine models of Alzheimer’s disease
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60. Antioxidants and cognitive training interact to affect oxidative stress and memory in APP/PSEN1 mice
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61. Blood–brain barrier impairment in dementia: Current and future in vivo assessments
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62. Parkin overexpression ameliorates hippocampal long-term potentiation and -amyloid load in an Alzheimer's disease mouse model
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63. Olive Biophenols Reduces Alzheimer’s Pathology in SH-SY5Y Cells and APPswe Mice
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64. Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease
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65. β-Sitosterol treatment attenuates cognitive deficits and prevents amyloid plaque deposition in amyloid protein precursor/presenilin 1 mice
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66. Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer’s disease
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67. Activation of CB2 receptor system restores cognitive capacity and hippocampal Sox2 expression in a transgenic mouse model of Alzheimer's disease
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68. Nutraceuticals: An emerging therapeutic approach against the pathogenesis of Alzheimer’s disease
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69. Cortical beta amyloid protein triggers an immune response, but no synaptic changes in the APPswe/PS1dE9 Alzheimer's disease mouse model
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70. <i>Retracted:</i> Mechanisms and effects of curcumin on spatial learning and memory improvement in APPswe/PS1dE9 mice
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71. Neuroprotective and restorative properties of the GLP-1/GIP dual agonist DA-JC1 compared with a GLP-1 single agonist in Alzheimer's disease
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72. Vitamin D2-Enriched Button Mushroom (Agaricus bisporus) Improves Memory in Both Wild Type and APPswe/PS1dE9 Transgenic Mice
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73. Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer’s disease
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74. Cerebral dopamine neurotrophic factor improves long-term memory in APP/PS1 transgenic mice modeling Alzheimer's disease as well as in wild-type mice
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75. An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice
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76. Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer’s disease alleviates amyloid-related pathologies in mice
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77. Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect on APP processing
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78. Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice
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79. Activation of Neurotensin Receptor 1 Facilitates Neuronal Excitability and Spatial Learning and Memory in the Entorhinal Cortex: Beneficial Actions in an Alzheimer's Disease Model
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80. Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer’s Disease
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81. Synaptic mitochondrial dysfunction and septin accumulation are linked to complement-mediated synapse loss in an Alzheimer’s disease animal model
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82. Modest Amyloid Deposition is Associated with Iron Dysregulation, Microglial Activation, and Oxidative Stress
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83. Encephalopathy induced by Alzheimer brain inoculation in a non-human primate
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84. Mouse models of Alzheimer’s disease cause rarefaction of pial collaterals and increased severity of ischemic stroke
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85. APP transgenic mice for modelling behavioural and psychological symptoms of dementia (BPSD)
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86. Quartz crystal microbalance analysis of growth kinetics for aggregation intermediates of the amyloid-β protein
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87. Optimized Turmeric Extract Reduces ?-Amyloid and Phosphorylated Tau Protein Burden in Alzheimer's Transgenic Mice
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88. Intravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA)
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89. Hemichannels Are Required for Amyloid -Peptide-Induced Degranulation and Are Activated in Brain Mast Cells of APPswe/PS1dE9 Mice
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91. Early-Onset and Robust Amyloid Pathology in a New Homozygous Mouse Model of Alzheimer's Disease
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93. Albiflorin ameliorates memory deficits in APP/PS1 transgenic mice via ameliorating mitochondrial dysfunction
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94. 7,8-Dihydroxyflavone improves memory consolidation processes in rats and mice
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95. S14G-Humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice
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