The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells

Biochemistry and molecular cell biology of diabetic complications

Brownlee, M. (2001) · Nature · doi:10.1038/414813a · Cited by 9,107 · see citing works

Global and societal implications of the diabetes epidemic

Zimmet, P., Alberti, K. G. M. M., & Shaw, J. (2001) · Nature · doi:10.1038/414782a · Cited by 5,883 · see citing works

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

Greene, L., & Tischler, A. S. (1976) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.73.7.2424 · Cited by 5,594 · see citing works

[42] Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal

Esterbauer, H., & Cheeseman, K. H. (1990) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(90)86134-h · Cited by 3,365 · see citing works

Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress

LeBel, C. P., Ischiropoulos, H., & Bondy, S. C. (1992) · Chemical Research in Toxicology · doi:10.1021/tx00026a012 · Cited by 2,694 · see citing works

Diabetes mellitus and the risk of dementia: The Rotterdam Study

Ott, A., Stolk, R. P., van Harskamp, F., Pols, H. A. P., Hofman, A., & Breteler, M. M. B. (1999) · Neurology · doi:10.1212/wnl.53.9.1937 · Cited by 2,175 · see citing works

Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin.

Barber, A. J., Lieth, E., Khin, S. A., Antonetti, D. A., Buchanan, A. G., & Gardner, T. W. (1998) · Journal of Clinical Investigation · doi:10.1172/jci2425 · Cited by 1,298 · see citing works

Oxidative Stress in the Pathogenesis of Diabetic Neuropathy

Vincent, A. M., Russell, J. W., Low, P. A., & Feldman, E. L. (2004) · Endocrine Reviews · doi:10.1210/er.2003-0019 · Cited by 988 · see citing works

The role of oxidative stress in the onset and progression of diabetes and its complications: asummary of a Congress Series sponsored byUNESCO-MCBN, the American Diabetes Association and the German Diabetes Society

R�sen, P., Nawroth, P., King, G. L., M�ller, W., Tritschler, H., & Packer, L. (2001) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.196 · Cited by 881 · see citing works

Cannabidiol and (−)Δ ⁹ -tetrahydrocannabinol are neuroprotective antioxidants

Hampson, A. J., Grimaldi, M., Axelrod, J., & Wink, D. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.14.8268 · Cited by 850 · see citing works

Endocannabinoid control of food intake and energy balance

Marzo, V. D., & Matias, I. (2005) · Nature Neuroscience · doi:10.1038/nn1457 · Cited by 746 · see citing works

The relationship between impaired glucose tolerance, type 2 diabetes, and cognitive function

Awad, N., Gagnon, M., & Messier, C. (2004) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390490514875 · Cited by 551 · see citing works

Is Type II Diabetes Associated With an Increased Risk of Cognitive Dysfunction?: A critical review of published studies

Strachan, M. W. J., Deary, I. J., Ewing, F. M. E., & Frier, B. M. (1997) · Diabetes Care · doi:10.2337/diacare.20.3.438 · Cited by 529 · cited 1× · see citing works

High glucose‐induced oxidative stress and mitochondrial dysfunction in neurons

Russell, J. W., Golovoy, D., Vincent, A. M., Mahendru, P., Olzmann, J. A., Mentzer, A., & Feldman, E. L. (2002) · The FASEB Journal · doi:10.1096/fj.01-1027com · Cited by 520 · see citing works

The Roles of Oxidative Stress and Antioxidant Treatment in Experimental Diabetic Neuropathy

Low, P. A., Nickander, K. K., & Tritschler, H. (1997) · Diabetes · doi:10.2337/diab.46.2.s38 · Cited by 440 · see citing works

Neurons Undergo Apoptosis in Animal and Cell Culture Models of Diabetes

Russell, J. W., Sullivan, K. A., Windebank, A. J., Herrmann, D. N., & Feldman, E. L. (1999) · Neurobiology of Disease · doi:10.1006/nbdi.1999.0254 · Cited by 411 · see citing works

An Experimental Model of Closed Head Injury in Mice: Pathophysiology, Histopathology, and Cognitive Deficits

Chen, Y., Constantini, S., Trembovler, V., Weinstock, M., & Shohami, E. (1996) · Journal of Neurotrauma · doi:10.1089/neu.1996.13.557 · Cited by 386 · see citing works

The Biochemical and Cellular Basis of Cell Proliferation Assays That Use Tetrazolium Salts

Berridge, M. V., Tan, A. S., McCoy, K. D., & Wang, R. (1996) · Cited by 375 · see citing works

Cognitive dysfunction in older subjects with diabetes mellitus: impact on diabetes self-management and use of care services

Sinclair, A. J., Girling, A. J., & Bayer, A. J. (2000) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(00)00195-9 · Cited by 362 · see citing works

Oxidative Stress and Programmed Cell Death in Diabetic Neuropathy

Vincent, A. M., Brownlee, M., & Russell, J. W. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb02108.x · Cited by 362 · see citing works

The therapeutic potential of cannabis

Baker, D., Pryce, G., Giovannoni, G., & Thompson, A. J. (2003) · The Lancet Neurology · doi:10.1016/s1474-4422(03)00381-8 · Cited by 344 · see citing works

Cerebral function in diabetes mellitus

Biessels, G. J., Kappelle, A. C., Bravenboer, B., Erkelens, D. W., & Gispen, W. H. (1994) · Diabetologia · doi:10.1007/bf00417687 · Cited by 341 · see citing works

Biochemical and pharmacological characterisatioN OF SR141716A, the first potent and selective brain cannabinoid receptor antagonist

Rinaldi, M. L., Barth, F., Héaulme, M., Alonso, R., Shire, D. J., Congy, C., Soubrié, P., Brelière, J.-C., & Fur, G. L. (1995) · Life Sciences · doi:10.1016/0024-3205(95)00174-5 · Cited by 303 · see citing works

Complications: Neuropathy, Pathogenetic Considerations

Greene, D. A., Sima, A. A. F., Stevens, M. J., Feldman, E. L., & Lattimer, S. A. (1992) · Diabetes Care · doi:10.2337/diacare.15.12.1902 · Cited by 300 · see citing works

Defective Adult Neurogenesis in CB1 Cannabinoid Receptor Knockout Mice

Jin, K., Xie, L., Kim, S. H., Parmentier‐Batteur, S., Sun, Y., Mao, X. O., Childs, J., & Greenberg, D. A. (2004) · Molecular Pharmacology · doi:10.1124/mol.66.2.204 · Cited by 271 · see citing works

BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells.

Giardino, I., Edelstein, D., & Brownlee, M. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118563 · Cited by 258 · see citing works

Glucose-induced oxidative stress and programmed cell death in diabetic neuropathy

Greene, D. A., Stevens, M. J., Obrosova, I. G., & Feldman, E. L. (1999) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00356-8 · Cited by 229 · see citing works

Neuroprotective Antioxidants from Marijuana a

Hampson, A. J., GRIMALDI, M., Miljkovic-Lolic, M., Wink, D. A., Rosenthal, R., & Axelrod, J. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06193.x · Cited by 203 · see citing works

Oxidative stress measurement by in vivo electron spin resonance spectroscopy in rats with streptozotocin-induced diabetes

Sano, T., Umeda, F., Hashimoto, T., Nawata, H., & Utsumi, H. (1998) · Diabetologia · doi:10.1007/s001250051076 · Cited by 195 · see citing works

Cannabinoid Receptors and Their Role in Neuroprotection

van der Stelt, M., & Marzo, V. D. (2005) · NeuroMolecular Medicine · doi:10.1385/nmm:7:1-2:037 · Cited by 189 · see citing works

The impact of diabetes on cognition: What can be learned from rodent models?

Biessels, G. J., & Gispen, W. H. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.08.015 · Cited by 172 · see citing works

Does diabetes target ganglion neurones?: Progressive sensory neurone involvement in long-term experimental diabetes

Zochodne, D. W. (2001) · Brain · doi:10.1093/brain/124.11.2319 · Cited by 156 · see citing works

Δ9-Tetrahydrocannabinol and Endogenous Cannabinoid Anandamide Directly Potentiate the Function of Glycine Receptors

Hejazi, N. S., Zhou, C., Öz, M., Sun, H., Ye, J. H., & Zhang, L. (2005) · Molecular Pharmacology · doi:10.1124/mol.105.019174 · Cited by 152 · see citing works

Anandamide induces apoptosis of PC‐12 cells: involvement of superoxide and caspase‐3

Sarker, K. P., Obara, S., Nakata, M., Kitajima, I., & Maruyama, I. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01425-3 · Cited by 151 · see citing works

New Insights Into Diabetic Polyneuropathy

Polydefkis, M. J. (2003) · JAMA · doi:10.1001/jama.290.10.1371 · Cited by 134 · see citing works

Pathogenesis of Diabetic Neuropathy

Stevens, M. J., Feldman, E. L., Thomas, T. P., & Greene, D. A. (1998) · Humana Press eBooks · doi:10.1007/978-1-4612-1816-6_2 · Cited by 131 · see citing works

Nutritional Status, Cognition, and Survival

Dagon, Y., Avraham, Y., Magen, I., Gertler, A., Ben‐Hur, T., & Berry, E. M. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m507607200 · Cited by 113 · see citing works

Psychomotor Slowing Is Associated With Distal Symmetrical Polyneuropathy in Adults With Diabetes Mellitus

Ryan, C. M., Williams, T. M., Orchard, T. J., & Finegold, D. N. (1992) · Diabetes · doi:10.2337/diab.41.1.107 · Cited by 107 · see citing works

Cannabinoids and Neuroprotection

Beltramo, M., Grundy, R. I., & Rabuffetti, M. (2001) · Molecular Neurobiology · doi:10.1385/mn:24:1-3:029 · Cited by 107 · see citing works

Diabetic Neuropathies: Features and Mechanisms

Zochodne, D. W. (1999) · Brain Pathology · doi:10.1111/j.1750-3639.1999.tb00233.x · Cited by 95 · see citing works

Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells

Bisogno, T., Katayama, K., Melck, D. J., Ueda, N., PETROCELLIS, L. D., Yamamoto, S., & Marzo, V. D. (1998) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1998.2540634.x · Cited by 94 · see citing works

Insulin Deficiency Rather than Hyperglycemia Accounts for Impaired Neurotrophic Responses and Nerve Fiber Regeneration in Type 1 Diabetic Neuropathy

Pierson, C. R., Zhang, W., Murakawa, Y., & Sima, A. A. F. (2003) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/62.3.260 · Cited by 74 · see citing works

Receptor-independent depression of DA and 5-HT uptake by cannabinoids in rat neocortex—involvement of Na+/K+-ATPase

Steffens, M., & Feuerstein, T. J. (2003) · Neurochemistry International · doi:10.1016/j.neuint.2003.08.009 · Cited by 74 · see citing works

Behavioral and biochemical effects of an ICV injection of streptozotocin in old Lewis rats

Blokland, A., & Jolles, J. (1994) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(94)90284-4 · Cited by 54 · see citing works

The synthetic cannabinoid WIN 55,212-2 increases COX-2 expression and PGE2 release in murine brain-derived endothelial cells following Theiler's virus infection

Mestre, L., Correa, F., Docagne, F., Clemente, D., & Guaza, C. (2006) · Biochemical Pharmacology · doi:10.1016/j.bcp.2006.06.037 · Cited by 54 · see citing works

Pathophysiology of central nervous system complications in diabetes mellitus.

Mooradian, A. D. (1997) · PubMed · Cited by 49 · see citing works

Reactive oxygen species, apoptosis and alte1red NGF-induced signaling in PC12 pheochromocytoma cells cultured in elevated glucose: AnIn Vitro cellular model for diabetic neuropathy

Lelkes, E., Unsworth, B. R., & Lelkes, P. I. (2001) · Neurotoxicity Research · doi:10.1007/bf03033191 · Cited by 47 · see citing works

Cannabinoids, endogenous ligands and synthetic analogs

Pop, E. (1999) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(99)80062-3 · Cited by 45 · see citing works

Noradrenaline release-inhibiting receptors on PC12 cells devoid of α2− and CB1 receptors: similarities to presynaptic imidazoline and edg receptors

Molderings, G. J., Bönisch, H., Hammermann, R., et al. (2002) · Neurochemistry International · doi:10.1016/s0197-0186(01)00076-6 · Cited by 44 · see citing works

Increased plasma oxidizability and decreased erythrocyte and plasma antioxidative capacity in patients with NIDDM.

Zaltzberg, H., KANTER, Y., Aviram, M., & Levy, Y. (1999) · PubMed · Cited by 43 · see citing works

Nerve regeneration in diabetic neuropathy

Apfel, S. C. (1999) · Diabetes Obesity and Metabolism · doi:10.1046/j.1463-1326.1999.00006.x · Cited by 30 · see citing works

Hyperglycemia Potentiates Carbonyl Stress-Induced Apoptosis in Naive PC-12 Cells: Relationship to Cellular Redox and Activator Protease Factor-1 Expression

Okouchi, M., Okayama, N., & Aw, T. Y. (2005) · Current Neurovascular Research · doi:10.2174/156720205774962665 · Cited by 29 · see citing works

Lack of correlation between NF-κB activation and induction of programmed cell death in PC12 pheochromocytoma cells treated with 6-hydroxydopamine or the cannabinoid receptor 1-agonist CP55,940

Erlandsson, N., Baumann, B., Rößler, O. G., et al. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(02)01228-5 · Cited by 11 · see citing works

Cannabinoids as Pharmacotherapies for Neuropathic Pain: From the Bench to the Bedside

Rahn, E. J., & Hohmann, A. G. (2009) · Neurotherapeutics · doi:10.1016/j.nurt.2009.08.002 · Cited by 305 · see citing works

Cannabinoid Ligand-Receptor Signaling During Early Pregnancy in the Mouse

Paria, B. C., Das, S., & Dey, S. K. (1999) · Humana Press eBooks · doi:10.1007/978-1-59259-710-9_40 · Cited by 3 · see citing works

Cannabinoid–improgan cross-tolerance: Improgan is a cannabinomimetic analgesic lacking affinity at the cannabinoid CB1 receptor

Nalwalk, J. W., Svokos, K. A., & Hough, L. B. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.08.035 · Cited by 9 · see citing works

Cannabinoid pharmacology: implications for additional cannabinoid receptor subtypes

Wiley, J. L., & Martin, B. R. (2002) · Chemistry and Physics of Lipids · doi:10.1016/s0009-3084(02)00146-9 · Cited by 100 · see citing works

Distribution of cannabinoid receptors in rat brain determined with aminoalkylindoles

Jansen, E. M., Haycock, D. A., Ward, S. J., & Seybold, V. S. (1992) · Brain Research · doi:10.1016/0006-8993(92)90428-c · Cited by 140 · see citing works

CB1 cannabinoid receptors mediate anxiolytic effects: convergent genetic and pharmacological evidence with CB1-specific agents

Haller, J., Varga, B., Ledent, C., & Freund, T. F. (2004) · Behavioural Pharmacology · doi:10.1097/01.fbp.0000135704.56422.40 · Cited by 241 · see citing works