Cited by 344Deep Brain Stimulation and Movement DisordersObsessive-Compulsive Spectrum DisordersTranscranial Magnetic Stimulation Studies

The DOI matches its Crossref record; 109 of the 109 references it cites were found in a registry or an index.

Mechanisms of action of deep brain stimulation (DBS)

Montgomery, Erwin B., Gale, John T.·2008·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2007.06.003

Open this paper in CoChat — free account

Abstract

Deep brain stimulation (DBS) is remarkably effective for a range of neurological and psychiatric disorders that have failed pharmacological and cell transplant therapies. Clinical investigations are underway for a variety of other conditions. Yet, the therapeutic mechanisms of action are unknown. In addition, DBS research demonstrates the need to re-consider many hypotheses regarding basal ganglia physiology and pathophysiology such as the notion that increased activity in the globus pallidus internal segment is causal to Parkinson's disease symptoms. Studies reveal a variety of apparently discrepant results. At the least, it is unclear which DBS effects are therapeutically effective. This systematic review attempts to organize current DBS research into a series of unifying themes or issues such as whether the therapeutic effects are local or systems-wide or whether the effects are related to inhibition or excitation. A number of alternative hypotheses are offered for consideration including suppression of abnormal activity, striping basal ganglia output of misinformation, reduction of abnormal stochastic resonance effects due to increased noise in the disease state, and reinforcement of dynamic modulation of neuronal activity by resonance effects.

Integrity signals

Registry

Crossref · 10.1016/j.neubiorev.2007.06.003

Cites

109 of 109 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The Concept of Mind
Ryle, G. (2006) · Rowman & Littlefield Publishers eBooks · doi:10.5040/9798216413257.ch-2 · Cited by 6,804
The functional anatomy of basal ganglia disorders
Albin, R. L., Young, A. B., & Penney, J. B. (1989) · Trends in Neurosciences · doi:10.1016/0166-2236(89)90074-x · Cited by 5,353
Primate models of movement disorders of basal ganglia origin
DeLong, M. R. (1990) · Trends in Neurosciences · doi:10.1016/0166-2236(90)90110-v · Cited by 3,824
Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus pallidus in Parkinson's disease.
Obeso, J., Olanow, C., Rodríguez-Oroz, M., Krack, P., Kumar, R., & Lang, A. E. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa000827 · Cited by 1,494
The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism
Bergman, H., Wichmann, T., Karmon, B., & DeLong, M. R. (1994) · Journal of Neurophysiology · doi:10.1152/jn.1994.72.2.507 · Cited by 1,366
A double‐blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
Olanow, C. W., Goetz, C. G., Kordower, J. H., Stoessl, A. J., Sossi, V., Brin, M. F., Shannon, K. M., Nauert, G. M., Perl, D. P., Godbold, J., et al. (2003) · Annals of Neurology · doi:10.1002/ana.10720 · Cited by 1,307
Weakly Connected Neural Networks
Hoppensteadt, F. C., & Izhikevich, E. M. (1997) · Applied mathematical sciences · doi:10.1007/978-1-4612-1828-9 · Cited by 1,261
Dopamine Dependency of Oscillations between Subthalamic Nucleus and Pallidum in Parkinson's Disease
Brown, P., Oliviero, A., Mazzone, P. A. M., Insola, A., Tonali, P. A., & Lazzaro, V. D. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-03-01033.2001 · Cited by 1,168
Stochastic resonance and sensory information processing: A tutorial and review of application
Moss, F., Ward, L. M., & Sannita, W. G. (2004) · Clinical Neurophysiology · doi:10.1016/j.clinph.2003.09.014 · Cited by 994
Stimulation of the Subthalamic Nucleus Changes the Firing Pattern of Pallidal Neurons
Hashimoto, T., Elder, C. M., Okun, M., Patrick, S. K., & Vitek, J. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-05-01916.2003 · Cited by 925
Reduction in subthalamic 8–35 Hz oscillatory activity correlates with clinical improvement in Parkinson's disease
Kühn, A. A., Kupsch, A. R., Schneider, G., & Brown, P. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04717.x · Cited by 895
Cellular Effects of Deep Brain Stimulation: Model-Based Analysis of Activation and Inhibition
McIntyre, C. C., Grill, W. M., Sherman, D. L., & Thakor, N. V. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00989.2003 · Cited by 817
Bilateral deep brain stimulation of the pedunculopontine and subthalamic nuclei in severe Parkinson's disease
Stefani, A., Lozano, A. M., Peppe, A., Stanzione, P., Galati, S., Tropepi, D., Pierantozzi, M., Brusa, L., Scarnati, E., & Mazzone, P. (2007) · Brain · doi:10.1093/brain/awl346 · Cited by 805
A basal ganglia pacemaker formed by the subthalamic nucleus and external globus pallidus
Plenz, D., & Kital, S. T. (1999) · Nature · doi:10.1038/23281 · Cited by 715
Activity Patterns in a Model for the Subthalamopallidal Network of the Basal Ganglia
Terman, D. H., Rubin, J. E., Yew, A. C., & Wilson, C. J. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-07-02963.2002 · Cited by 690
Neurons in the globus pallidus do not show correlated activity in the normal monkey, but phase-locked oscillations appear in the MPTP model of parkinsonism
Nini, A., Feingold, A., Slovin, H., & Bergman, H. (1995) · Journal of Neurophysiology · doi:10.1152/jn.1995.74.4.1800 · Cited by 653
Move to the rhythm: oscillations in the subthalamic nucleus–external globus pallidus network
Bevan, M. D. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02235-x · Cited by 633
High-frequency Synchronization of Neuronal Activity in the Subthalamic Nucleus of Parkinsonian Patients with Limb Tremor
Levy, R., Hutchison, W. D., Lozano, A. M., & Dostrovsky, J. O. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-20-07766.2000 · Cited by 610
High Frequency Stimulation of the Subthalamic Nucleus Eliminates Pathological Thalamic Rhythmicity in a Computational Model
Rubin, J. E., & Terman, D. H. (2004) · Journal of Computational Neuroscience · doi:10.1023/b:jcns.0000025686.47117.67 · Cited by 602
Basal ganglia local field potential activity: Character and functional significance in the human
Brown, P., & Williams, D. R. (2005) · Clinical Neurophysiology · doi:10.1016/j.clinph.2005.05.009 · Cited by 547
High-Frequency Stimulation Produces a Transient Blockade of Voltage-Gated Currents in Subthalamic Neurons
Beurrier, C., Bioulac, B. H., Audin, J., & Hammond, C. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.4.1351 · Cited by 532
Deep brain stimulation for refractory obsessive-compulsive disorder
Abelson, J. L., Curtis, G. C., Sagher, O., Albucher, R. C., Harrigan, M., Taylor, S. F., Martis, B., & Giordani, B. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.042 · Cited by 522
High‐frequency unilateral thalamic stimulation in the treatment of essential and parkinsonian tremor
Koller, W., Pahwa, R., Busenbark, K., Hubble, J., Wilkinson, S., Lang, A., Tuite, P., Sime, E., Lazano, A., Hauser, R., et al. (1997) · Annals of Neurology · doi:10.1002/ana.410420304 · Cited by 516
Dopamine-dependent changes in the functional connectivity between basal ganglia and cerebral cortex in humans
Williams, D. (2002) · Brain · doi:10.1093/brain/awf156 · Cited by 511
Microstimulation-Induced Inhibition of Neuronal Firing in Human Globus Pallidus
Dostrovsky, J. O., Levy, R., Wu, J. P., Hutchison, W. D., Tasker, R. R., & Lozano, A. M. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.84.1.570 · Cited by 470
Bilateral deep brain stimulation of the pedunculopontine nucleus for Parkinson's disease
Plaha, P., & Gill, S. S. (2005) · Neuroreport · doi:10.1097/01.wnr.0000187637.20771.a0 · Cited by 451
Patterning of globus pallidus local field potentials differs between Parkinson's disease and dystonia
Silberstein, P. (2003) · Brain · doi:10.1093/brain/awg267 · Cited by 435
The interpretation of spike potentials of motoneurones
Coombs, J. S., Curtis, D., & Eccles, J. C. (1957) · The Journal of Physiology · doi:10.1113/jphysiol.1957.sp005887 · Cited by 382
Subthalamic high frequency stimulation resets subthalamic firing and reduces abnormal oscillations
Meissner, W. G., Leblois, A., Hansel, D., Bioulac, B. H., Gross, C. E., Benazzouz, A., & Boraud, T. (2005) · Brain · doi:10.1093/brain/awh616 · Cited by 348
Effect of high-frequency stimulation of the subthalamic nucleus on the neuronal activities of the substantia nigra pars reticulata and ventrolateral nucleus of the thalamus in the rat
Benazzouz, A., Gao, D. M., Ni, Z., Piallat, B., Bouali‐Benazzouz, R., & Benabid, A. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00199-8 · Cited by 338
Effects of high frequency stimulation of subthalamic nucleus on extracellular glutamate and GABA in substantia nigra and globus pallidus in the normal rat
Windels, F., Bruet, N., Poupard, A., Urbain, N., Chouvet, G., Feuerstein, C., & Savasta, M. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00296.x · Cited by 334
Excitation of Central Nervous System Neurons by Nonuniform Electric Fields
McIntyre, C. C., & Grill, W. M. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77251-6 · Cited by 319
Neuronal Oscillations in the Basal Ganglia and Movement Disorders: Evidence from Whole Animal and Human Recordings: Figure 1.
Hutchison, W. D., Dostrovsky, J. O., Walters, J. R., Courtemanche, R., Boraud, T., Goldberg, J. A., & Brown, P. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3366-04.2004 · Cited by 305
Bilateral high-frequency stimulation in the subthalamic nucleus for the treatment of Parkinson disease: correlation of therapeutic effect with anatomical electrode position
Voges, J., Volkmann, J., Allert, N., Lehrke, R., Koulousakis, A., Freund, H., & Sturm, V. (2002) · Journal of neurosurgery · doi:10.3171/jns.2002.96.2.0269 · Cited by 301
Stimulation-induced inhibition of neuronal firing in human subthalamic nucleus
Filali, M., Hutchison, W. D., Palter, V. N., Lozano, A. M., & Dostrovsky, J. O. (2004) · Experimental Brain Research · doi:10.1007/s00221-003-1784-y · Cited by 300
Synchronized Neuronal Discharge in the Basal Ganglia of Parkinsonian Patients Is Limited to Oscillatory Activity
Levy, R., Hutchison, W. D., Lozano, A. M., & Dostrovsky, J. O. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-07-02855.2002 · Cited by 290
Effects of High-Frequency Stimulation in the Internal Globus Pallidus on the Activity of Thalamic Neurons in the Awake Monkey
Anderson, M. E., Postupna, N. O., & Ruffo, M. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00475.2002 · Cited by 280
Handbook of Parkinson's Disease
Pahwa, R., & Lyons, K. (2013) · CRC Press eBooks · doi:10.1201/b14361 · Cited by 272
Mechanisms of deep brain stimulation and future technical developments
Erwin, B., Montgomery, M., Jr., & Baker, K. K. (2000) · Neurological Research · doi:10.1080/01616412.2000.11740668 · Cited by 265
Basal ganglia motor control. II. Late pallidal timing relative to movement onset and inconsistent pallidal coding of movement parameters
Mink, J. W., & Thach, W. T. (1991) · Journal of Neurophysiology · doi:10.1152/jn.1991.65.2.301 · Cited by 264
Electrophysiological and metabolic evidence that high‐frequency stimulation of the subthalamic nucleus bridles neuronal activity in the subthalamic nucleus and the substantia nigra reticulata
Tai, C., Boraud, T., Bézard, E., Bioulac, B. H., Gross, C. E., & Benazzouz, A. (2003) · The FASEB Journal · doi:10.1096/fj.03-0163com · Cited by 261
Deep brain stimulation of the subthalamic nucleus: anatomical, neurophysiological, and outcome correlations with the effects of stimulation
Lanotte, M. (2002) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.72.1.53 · Cited by 256
Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: effects of variation in stimulation parameters
Rizzone, M. G. (2001) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.71.2.215 · Cited by 248
Dynamics of tremor-related oscillations in the human globus pallidus: a single case study
Hurtado, J. M., Gray, C. M., Tamas, L. B., & Sigvardt, K. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.4.1674 · Cited by 246
Dual Effect of High-Frequency Stimulation on Subthalamic Neuron Activity
García, L., Audin, J., D’Alessandro, G., Bioulac, B. H., & Hammond, C. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-25-08743.2003 · Cited by 245
Bad oscillations in Parkinson’s disease
Brown, P. (2006) · Springer eBooks · doi:10.1007/978-3-211-45295-0_6 · Cited by 218
Deep Brain Stimulation in Epilepsy
Loddenkemper, T., Pan, A., Neme-Mercante, S., Baker, K. B., Rezai, A. R., Dinner, D. S., Montgomery, E. B., & Lüders, H. O. (2001) · Journal of Clinical Neurophysiology · doi:10.1097/00004691-200111000-00002 · Cited by 217
Self-citation
Spontaneous and Evoked Activity of Substantia Nigra Pars Reticulata Neurons during High-Frequency Stimulation of the Subthalamic Nucleus
Maurice, N., Thierry, A. M., Glowinski, J., & Deniau, J. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-30-09929.2003 · Cited by 216
Deep brain stimulation for Parkinson’s disease dissociates mood and motor circuits: a functional MRI case study
Stefurak, T., Mikulis, D., Mayberg, H., Lang, A. E., Hevenor, S., Pahapill, P., Saint‐Cyr, J., & Lozano, A. (2003) · Movement Disorders · doi:10.1002/mds.10593 · Cited by 215
Globus pallidus internus deep brain stimulation for dystonic conditions: A prospective audit
Yianni, J., Bain, P. G., Giladi, N., Auca, M., Gregory, R. P., Joint, C., Nandi, D., Stein, J. F., Scott, R., & Aziz, T. Z. (2003) · Movement Disorders · doi:10.1002/mds.10380 · Cited by 194
Does stimulation of the GPi control dyskinesia by activating inhibitory axons?
Wu, Y.-Y., Levy, R., Ashby, P., Tasker, R. R., & Dostrovsky, J. O. (2001) · Movement Disorders · doi:10.1002/mds.1046 · Cited by 181
Deep Brain Stimulation for Epilepsy
Koch, P., & Baltuch, G. H. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-805353-9.00083-8 · Cited by 181
Blood flow responses to deep brain stimulation of thalamus
Perlmutter, J. S., Mink, J. W., Bastian, A. J., Zackowski, K. M., Hershey, T. G., Miyawaki, E. K., Koller, W. C., & Videen, T. O. (2002) · Neurology · doi:10.1212/wnl.58.9.1388 · Cited by 175
High-frequency stimulation of the subthalamic nucleus silences subthalamic neurons: a possible cellular mechanism in Parkinson’s disease
Magariños-Ascone, C. M., Pazo, J. H., Macadar, O., & Buño, W. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00538-9 · Cited by 169
Balance of Monosynaptic Excitatory and Disynaptic Inhibitory Responses of the Globus Pallidus Induced after Stimulation of the Subthalamic Nucleus in the Monkey
Kita, H., Tachibana, Y., Nambu, A., & Chiken, S. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1719-05.2005 · Cited by 161
Complex Locking Rather Than Complete Cessation of Neuronal Activity in the Globus Pallidus of a 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Primate in Response to Pallidal Microstimulation
Bar‐Gad, I., Elias, S., Vaadia, E., & Bergman, H. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1691-04.2004 · Cited by 160
Neurophysiological effects of stimulation through electrodes in the human subthalamic nucleus
Ashby, P., Kim, Y. J., Kumar, R., Lang, A. E., & Lozano, A. M. (1999) · Brain · doi:10.1093/brain/122.10.1919 · Cited by 159
Neurotransmitter release from high-frequency stimulation of the subthalamic nucleus
Lee, K. H., Chang, S.-Y., Roberts, D. W., & Kim, U. (2004) · Journal of neurosurgery · doi:10.3171/jns.2004.101.3.0511 · Cited by 159
Inhibitory processes and interneuronal apparatus in motor cortex during sleep and waking. I. Background firing and responsiveness of pyramidal tract neurons and interneurons.
Steriade, M., Deschênes, M., & Oakson, G. (1974) · Journal of Neurophysiology · doi:10.1152/jn.1974.37.5.1065 · Cited by 159
MECHANISMS OF SUPRASPINAL ACTIONS UPON SPINAL CORD ACTIVITIES. RETICULAR INHIBITORY MECHANISMS UPON FLEXOR MOTONEURONS
Llinas, R. H., & Terzuolo, C. A. (1965) · Journal of Neurophysiology · doi:10.1152/jn.1965.28.2.413 · Cited by 158
Subthalamic nucleus deep brain stimulus evoked potentials: Physiological and therapeutic implications
Baker, K. B., Montgomery, E. B., Rezai, A. R., Burgess, R. C., & Lüders, H. O. (2002) · Movement Disorders · doi:10.1002/mds.10206 · Cited by 155
Self-citation
Multisecond Oscillations in Firing Rate in the Basal Ganglia: Robust Modulation by Dopamine Receptor Activation and Anesthesia
Ruskin, D. N., Bergstrom, D. A., Kaneoke, Y., Patel, B. N., Twery, M. J., & Walters, J. R. (1999) · Journal of Neurophysiology · doi:10.1152/jn.1999.81.5.2046 · Cited by 147
Effects of GPi stimulation on human thalamic neuronal activity
Montgomery, E. B. (2006) · Clinical Neurophysiology · doi:10.1016/j.clinph.2006.08.011 · Cited by 145
Self-citation
MECHANISMS OF SUPRASPINAL ACTIONS UPON SPINAL CORD ACTIVITIES. RETICULAR INHIBITORY MECHANISMS ON ALPHA-EXTENSOR MOTONEURONS
Llinas, R. H., & Terzuolo, C. A. (1964) · Journal of Neurophysiology · doi:10.1152/jn.1964.27.4.579 · Cited by 143
Frequency-Dependent Reciprocal Modulation of Verbal Fluency and Motor Functions in Subthalamic Deep Brain Stimulation
Wojtecki, L., Timmermann, L., Jörgens, S., Südmeyer, M., Maarouf, M., Treuer, H., Groß, J., Lehrke, R., Koulousakis, A., Voges, J., et al. (2006) · Archives of Neurology · doi:10.1001/archneur.63.9.1273 · Cited by 141
Neuronal activity in the striatum and pallidum of primates related to the execution of externally cued reaching movements
Jaeger, D., Gilman, S., & Aldridge, J. W. (1995) · Brain Research · doi:10.1016/0006-8993(95)00780-t · Cited by 134
Disturbances of Rhythm Formation in Patients with Parkinson's Disease: Part I. Characteristics of Tapping Response to the Periodic Signals
Nakamura, R., Nagasaki, H., & Narabayashi, H. (1978) · Perceptual and Motor Skills · doi:10.2466/pms.1978.46.1.63 · Cited by 130
Subthalamic stimulation activates internal pallidus: Evidence from cGMP microdialysis in PD patients
Stefani, A., Fedele, E., Galati, S., Pepicelli, O., Frasca, S., Pierantozzi, M., Peppe, A., Brusa, L., Orlacchio, A., Hainsworth, A. H., et al. (2005) · Annals of Neurology · doi:10.1002/ana.20402 · Cited by 129
Acute stimulation in the external segment of the globus pallidus improves parkinsonian motor signs
Vitek, J. L., Hashimoto, T., Peoples, J., DeLong, M. R., & Bakay, R. A. E. (2004) · Movement Disorders · doi:10.1002/mds.20137 · Cited by 127
Frequency dependent effects of subthalamic nucleus stimulation in Parkinson's disease
Fogelson, N., Kühn, A. A., Silberstein, P., Limousin, P. D., Hariz, M. I., Trottenberg, T., Kupsch, A. R., & Brown, P. (2005) · Neuroscience Letters · doi:10.1016/j.neulet.2005.02.050 · Cited by 124
Selective Attenuation of Afferent Synaptic Transmission as a Mechanism of Thalamic Deep Brain Stimulation-Induced Tremor Arrest
Anderson, T. R., Hu, B., Iremonger, K. J., & Kiss, Z. H. T. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3523-05.2006 · Cited by 113
Subthalamic nucleus stimulation modulates motor cortex oscillatory activity in Parkinson's disease
Devos, D. (2004) · Brain · doi:10.1093/brain/awh053 · Cited by 111
Visually Guided Movements Suppress Subthalamic Oscillations in Parkinson's Disease Patients
Amirnovin, R., Williams, Z. M., Cosgrove, G. R., & Eskandar, E. N. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3242-04.2004 · Cited by 106
Modifications of precentral cortex discharge and EMG activity in monkeys with MPTP-induced lesions of DA nigral neurons
Doudet, D. J., Gross, C. E., Arluison, M., & Bioulac, B. H. (1990) · Experimental Brain Research · doi:10.1007/bf00228859 · Cited by 102
Extradural motor cortex stimulation for advanced Parkinson disease
Canavero, S., Paolotti, R., Bonicalzi, V., Castellano, G., Crasto, S. G., Rizzo, L. B., Davini, O., Zenga, F., & Ragazzi, P. (2002) · Journal of neurosurgery · doi:10.3171/jns.2002.97.5.1208 · Cited by 97
Reciprocal interactions between oscillatory activities of different frequencies in the subthalamic region of patients with Parkinson's disease
Fogelson, N., Pogosyan, A. H., Kühn, A. A., Kupsch, A. R., Bruggen, G. V., Speelman, H. D., Tijssen, M. A. J., Quartarone, A., Insola, A., Mazzone, P. A. M., et al. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04179.x · Cited by 96
Chronic thalamic stimulation for the tremor of multiple sclerosis
Montgomery, E. B., Baker, K. B., Kinkel, R. P., & Barnett, G. H. (1999) · Neurology · doi:10.1212/wnl.53.3.625 · Cited by 94
Self-citation
Cellular Mechanisms Preventing Sustained Activation of Cortex During Subcortical High-Frequency Stimulation
Iremonger, K. J., Anderson, T. R., Hu, B., & Kiss, Z. H. T. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00105.2006 · Cited by 93
The oscillatory activity in the Parkinsonian subthalamic nucleus investigated using the macro-electrodes for deep brain stimulation
Liu, X., Ford-Dunn, H. L., Hayward, G., Nandi, D., Miall, R. C., Aziz, T. Z., & Stein, J. F. (2002) · Clinical Neurophysiology · doi:10.1016/s1388-2457(02)00256-0 · Cited by 92
Analysis of the electrical excitation of CNS neurons
Rattay, F. (1998) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.678611 · Cited by 89
Bradykinesia in early Huntington’s disease
Sánchez‐Pernaute, R., Künig, G., Alba, A. D. B., de Yébenes, J. G., Vontobel, P., & Leenders, K. L. (2000) · Neurology · doi:10.1212/wnl.54.1.119 · Cited by 85
Neuronal response to local electrical stimulation in rat thalamus: physiological implications for mechanisms of deep brain stimulation
Kiss, Z. H. T., Mooney, D., Renaud, L. P., & Hu, B. (2002) · Neuroscience · doi:10.1016/s0306-4522(02)00122-7 · Cited by 82
DBS therapy for the vegetative state and minimally conscious state
Yamamoto, T., Kobayashi, K., Kasai, M., Oshima, H., Fukaya, C., & Katayama, Y. (2005) · Acta neurochirurgica. Supplementum · doi:10.1007/3-211-27577-0_17 · Cited by 77
Handbook of Parkinson's Disease
(2003) · CRC Press eBooks · doi:10.1201/9780203912164 · Cited by 77
Inhibition of voluntary activity by thalamic stimulation in humans: Relevance for the control of tremor
Strafella, A. P., Ashby, P., Munz, M., Dostrovsky, J. O., Lozano, A. M., & Lang, A. E. (1997) · Movement Disorders · doi:10.1002/mds.870120517 · Cited by 72
Chapter 78 How does DBS work?
Lozano, A. M., & Eltahawy, H. A. (2004) · Supplements to Clinical neurophysiology · doi:10.1016/s1567-424x(09)70414-3 · Cited by 71
Brain Dynamics and the Striatal Complex
Miller, R. J., & Wickens, J. (2000) · CRC Press eBooks · doi:10.1201/9781482283556 · Cited by 66
Somatosensory evoked high-frequency oscillation in Parkinson's disease and myoclonus epilepsy
Mochizuki, H., Ugawa, Y., Machii, K., Terao, Y., Hanajima, R., Furubayashi, T., Uesugi, H., & Kanazawa, I. (1999) · Clinical Neurophysiology · doi:10.1016/s0168-5597(98)00057-4 · Cited by 65
The periodogram and its optical analogy
Schuster, A. (1906) · Proceedings of the Royal Society of London Series A Containing Papers of a Mathematical and Physical Character · doi:10.1098/rspa.1906.0011 · Cited by 64
Muscle sounds in Parkinson's disease
Brown, P. (1997) · The Lancet · doi:10.1016/s0140-6736(97)80086-4 · Cited by 60
The striatum and motor cortex in motor initiation and execution
Montgomery, E. B., & Buchholz, S. R. (1991) · Brain Research · doi:10.1016/0006-8993(91)90461-4 · Cited by 58
Self-citation
Therapeutic extradural cortical stimulation for movement disorders: A review
Canavero, S., Bonicalzi, V., Paolotti, R., Castellano, G., Crasto, S. G., Rizzo, L. B., Davini, O., & Maina, R. (2003) · Neurological Research · doi:10.1179/016164103101201238 · Cited by 55
Effect of deep brain stimulation on amplitude and frequency characteristics of rest tremor in Parkinson's disease
Beuter, A. C. (2001) · Thalamus & Related Systems · doi:10.1016/s1472-9288(01)00020-6 · Cited by 53
Methods for isolating extracellular action potentials and removing stimulus artifacts from microelectrode recordings of neurons requiring minimal operator intervention
Montgomery, E. B., Gale, J. T., & He, H. (2004) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2004.10.017 · Cited by 48
Self-citation
Effect of subthalamic nucleus stimulation patterns on motor performance in Parkinson's disease
Montgomery, E. B. (2005) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2004.12.002 · Cited by 44
Self-citation
Dynamically Coupled, High-Frequency Reentrant, Non-linear Oscillators Embedded in Scale-Free Basal Ganglia-Thalamic-Cortical Networks Mediating Function and Deep Brain Stimulation Effects
Montgomery, E. B. (2004) · Nonlinear studies · Cited by 39
Self-citation
Elevations in local gamma activity are accompanied by changes in the firing rate and information coding capacity of neurons in the region of the subthalamic nucleus in Parkinson's disease
Pogosyan, A. H., Kühn, A. A., Trottenberg, T., Schneider, G., Kupsch, A. R., & Brown, P. (2006) · Experimental Neurology · doi:10.1016/j.expneurol.2006.06.014 · Cited by 39
Deep brain stimulation for hyperkinetic disorders
Montgomery, E. B. (2004) · Neurosurgical FOCUS · doi:10.3171/foc.2004.17.1.1 · Cited by 37
Self-citation
Intermuscular coherence in Parkinson's disease: relationship to bradykinesia
Brown, P., Marsden, J. F., Defebvre, L., Cassim, F., Mazzone, P. A. M., Oliviero, A., Altibrandi, M. G., Lazzaro, V. D., Limousin, P. D., Fraix, V., et al. (2001) · Neuroreport · doi:10.1097/00001756-200108080-00057 · Cited by 36
Visualization of synaptic markers in the optic neuropils ofDrosophila using a new constrained deconvolution method
Hiesinger, P. R., Scholz, M., Meinertzhagen, I. A., Fischbach, K., & Obermayer, K. (2000) · The Journal of Comparative Neurology · doi:10.1002/1096-9861(20000108)429:2 · Cited by 35
Disturbances of Rhythm Formation in Patients with Parkinson's Disease: Part II. A Forced Oscillation Model
Nagasaki, H., Nakamura, R., & Taniguchi, R. (1978) · Perceptual and Motor Skills · doi:10.2466/pms.1978.46.1.79 · Cited by 33
The Optimal Stimulation Site for Chronic Stimulation of the Subthalamic Nucleus in Parkinson’s Disease
Yokoyama, T., Sugiyama, K., Nishizawa, S., Yokota, N., Ohta, S., Akamine, S., & Namba, H. (2001) · Stereotactic and Functional Neurosurgery · doi:10.1159/000064598 · Cited by 31
Involvement of Human Thalamic Neurons in Internally and Externally Generated Movements
MacMillan, M., Dostrovsky, J. O., Lozano, A. M., & Hutchison, W. D. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00835.2003 · Cited by 30
Detection of neuronal periodic oscillations in the basal ganglia of normal and parkinsonian monkeys.
Karmon, B., & Bergman, H. (1993) · PubMed · Cited by 24
Levodopa reversible loss of the Piper frequency oscillation component in Parkinson's disease
McAuley, J. (2001) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.70.4.471 · Cited by 22
Brain Dynamics and the Striatal Complex
Wickens, J. R. (2000) · Taylor & Francis eBooks · doi:10.4324/9780203304914 · Cited by 19
Neurophysiology/circuitry
Montgomery, E. B. (2003) · Neurological disease and therapy · doi:10.1201/9780203912164.ch11 · Cited by 3
Self-citation
Axonal loss in multiple sclerosis lesions: magnetic resonance imaging insights substrates of disability
Sperfeld (1999) · Pure Amsterdam UMC · doi:10.1002/1531-8249(199911)46:5 · Cited by 2
Untitled work
Waldvogel (1999) · doi:10.1002/1531-8249(199907)46:1

Flagged first, then by citations

Research works printed but not linked: 3

Mandir, 1989, Changes in motor cortex neuronal activity associated with increased reaction time in MPTP parkinsonism, Sociological Neuroscience Abstract, 15, 787
Montgomery, 1993, Abnormal dynamic modulation of putamen neuronal activity following MPTP, Sociological Neuroscience Abstract, 19, 1051
Montgomery, 2002, Deep brain stimulation. Neuroprosthetics: theory and practice, Vol. 2, 915

Sorted by citations

Hydrogel bioelectronics
Yuk, H., Lu, B., & Zhao, X. (2018) · Chemical Society Reviews · doi:10.1039/c8cs00595h · Cited by 2,148
The neural basis of the speed–accuracy tradeoff
Bogacz, R., Wagenmakers, E., Forstmann, B. U., & Nieuwenhuis, S. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.09.002 · Cited by 754
Revealing neuronal function through microelectrode array recordings
Obien, M. E. J., Deligkaris, K., Bullmann, T., Bakkum, D. J., & Frey, U. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00423 · Cited by 705
Probing and regulating dysfunctional circuits using deep brain stimulation
Lozano, A. M., & Lipsman, N. (2013) · Neuron · doi:10.1016/j.neuron.2013.01.020 · Cited by 665
Linking Molecules to Mood: New Insight Into the Biology of Depression
Krishnan, V., & Nestler, E. J. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.10030434 · Cited by 666

See all 344

Authors: Montgomery, E. B., & Gale, J. T.
Affiliations: University of Wisconsin–Madison (US)
Harvard University (US)
Corresponding author: Montgomery, Erwin B.
ORCID: Montgomery, Erwin B.
Gale, John T.
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2008-01
Volume: 32
Issue: 3
Pages: 388-407
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2007.06.003
OpenAlex: W2143662434
Cited by: 344
References: 109
Citations by year: 2026: 9 · 2025: 8 · 2024: 13 · 2023: 14 · 2022: 14 · 2021: 12 · 2020: 12 · 2019: 18 · 2018: 16 · 2017: 22 · 2016: 19 · 2015: 24 · 2014: 27 · 2013: 28 · 2012: 38
FWCI: 2.03
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion)
PubMed (publishedVersion)
Funders: National Center for Research Resources (C06RR020141, RR 15459-01, C06RR015459, RR 020141-01, P51RR000167)
Topics: Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
Keywords: deep brain stimulation, mechanism of action, basal ganglia, Parkinson's disease, globus pallidus internus, therapeutic effects, stochastic resonance, basal ganglia output, neuropsychiatric disorders
MeSH terms: Basal Ganglia, Humans, Neural Inhibition, Neural Pathways, Synaptic Transmission, Neurons, Parkinson Disease, Deep Brain Stimulation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Mechanisms of action of deep brain stimulation (DBS)

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks