Cited by 344Deep Brain Stimulation and Movement DisordersObsessive-Compulsive Spectrum DisordersTranscranial Magnetic Stimulation Studies

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Mechanisms of action of deep brain stimulation (DBS)

Montgomery, Erwin B., Gale, John T.·2008·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2007.06.003

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Abstract

Deep brain stimulation (DBS) is remarkably effective for a range of neurological and psychiatric disorders that have failed pharmacological and cell transplant therapies. Clinical investigations are underway for a variety of other conditions. Yet, the therapeutic mechanisms of action are unknown. In addition, DBS research demonstrates the need to re-consider many hypotheses regarding basal ganglia physiology and pathophysiology such as the notion that increased activity in the globus pallidus internal segment is causal to Parkinson's disease symptoms. Studies reveal a variety of apparently discrepant results. At the least, it is unclear which DBS effects are therapeutically effective. This systematic review attempts to organize current DBS research into a series of unifying themes or issues such as whether the therapeutic effects are local or systems-wide or whether the effects are related to inhibition or excitation. A number of alternative hypotheses are offered for consideration including suppression of abnormal activity, striping basal ganglia output of misinformation, reduction of abnormal stochastic resonance effects due to increased noise in the disease state, and reinforcement of dynamic modulation of neuronal activity by resonance effects.

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The Concept of Mind
Ryle, G. (2006) · Rowman & Littlefield Publishers eBooks · doi:10.5040/9798216413257.ch-2 · Cited by 6,804
The functional anatomy of basal ganglia disorders
Albin, R. L., Young, A. B., & Penney, J. B. (1989) · Trends in Neurosciences · doi:10.1016/0166-2236(89)90074-x · Cited by 5,353
Primate models of movement disorders of basal ganglia origin
DeLong, M. R. (1990) · Trends in Neurosciences · doi:10.1016/0166-2236(90)90110-v · Cited by 3,824
Deep-brain stimulation of the subthalamic nucleus or the pars interna of the globus pallidus in Parkinson's disease.
Obeso, J., Olanow, C., Rodríguez-Oroz, M., Krack, P., Kumar, R., & Lang, A. E. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa000827 · Cited by 1,494
The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism
Bergman, H., Wichmann, T., Karmon, B., & DeLong, M. R. (1994) · Journal of Neurophysiology · doi:10.1152/jn.1994.72.2.507 · Cited by 1,366
A double‐blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
Olanow, C. W., Goetz, C. G., Kordower, J. H., Stoessl, A. J., Sossi, V., Brin, M. F., Shannon, K. M., Nauert, G. M., Perl, D. P., Godbold, J., et al. (2003) · Annals of Neurology · doi:10.1002/ana.10720 · Cited by 1,307
Weakly Connected Neural Networks
Hoppensteadt, F. C., & Izhikevich, E. M. (1997) · Applied mathematical sciences · doi:10.1007/978-1-4612-1828-9 · Cited by 1,261
Dopamine Dependency of Oscillations between Subthalamic Nucleus and Pallidum in Parkinson's Disease
Brown, P., Oliviero, A., Mazzone, P. A. M., Insola, A., Tonali, P. A., & Lazzaro, V. D. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-03-01033.2001 · Cited by 1,168
Stochastic resonance and sensory information processing: A tutorial and review of application
Moss, F., Ward, L. M., & Sannita, W. G. (2004) · Clinical Neurophysiology · doi:10.1016/j.clinph.2003.09.014 · Cited by 994
Stimulation of the Subthalamic Nucleus Changes the Firing Pattern of Pallidal Neurons
Hashimoto, T., Elder, C. M., Okun, M., Patrick, S. K., & Vitek, J. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-05-01916.2003 · Cited by 925

Show all 109 references

Research works printed but not linked: 3

Mandir, 1989, Changes in motor cortex neuronal activity associated with increased reaction time in MPTP parkinsonism, Sociological Neuroscience Abstract, 15, 787
Montgomery, 1993, Abnormal dynamic modulation of putamen neuronal activity following MPTP, Sociological Neuroscience Abstract, 19, 1051
Montgomery, 2002, Deep brain stimulation. Neuroprosthetics: theory and practice, Vol. 2, 915

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Authors: Montgomery, E. B., & Gale, J. T.
Affiliations: University of Wisconsin–Madison (US)
Harvard University (US)
Corresponding author: Montgomery, Erwin B.
ORCID: Montgomery, Erwin B.
Gale, John T.
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2008-01
Volume: 32
Issue: 3
Pages: 388-407
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2007.06.003
OpenAlex: W2143662434
Cited by: 344
References: 109
Citations by year: 2026: 9 · 2025: 8 · 2024: 13 · 2023: 14 · 2022: 14 · 2021: 12 · 2020: 12 · 2019: 18 · 2018: 16 · 2017: 22 · 2016: 19 · 2015: 24 · 2014: 27 · 2013: 28 · 2012: 38
FWCI: 2.03
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion)
PubMed (publishedVersion)
Funders: National Center for Research Resources (C06RR020141, RR 15459-01, C06RR015459, RR 020141-01, P51RR000167)
Topics: Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
Keywords: deep brain stimulation, mechanism of action, basal ganglia, Parkinson's disease, globus pallidus internus, therapeutic effects, stochastic resonance, basal ganglia output, neuropsychiatric disorders
MeSH terms: Basal Ganglia, Humans, Neural Inhibition, Neural Pathways, Synaptic Transmission, Neurons, Parkinson Disease, Deep Brain Stimulation

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