From flexible electronics technology in the era of IoT and artificial intelligence toward future implanted body sensor networks
Open accessAbstract
Flexible electronics technology dramatically changes the capability of sensors, which allows us to detect human biological signals not only on the skin but also inside the human body. Wearable sensors that stick to the skin surface can detect various biomechanical movements, biological signals, and byproducts such as useful elements from sweat and body temperature. On the other hand, implantable sensors directly or indirectly contact with biological components inside the body, such as tissue, organs, or muscles, to support or treat bodily functions or problems. With the development of these advanced sensors, we can live together with a huge number of sensors in the future. Toward body sensor networks that can be fully implanted in the future, sustainable energy sources that support the operation of sensors as well as the development of materials that enable long-term use inside the body remain challenges. In this review, we first summarize various state-of-the-art sensors in terms of flexible and wearable platforms. Additionally, we review the recent research trends of energy harvesters in mechanical and thermal energy conversion into useful electricity for the operation of the sensors. Furthermore, we cover recent studies in the aspect of materials for implantable sensors. Finally, we discuss future direction of the sensors that may enable implanted body sensor networks in the body.
AI snapshot
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TL;DR
This review surveys flexible electronics for wearable and implantable sensors, stimulators, neural interfaces, and energy harvesters, including biodegradable and 2D-material devices, as steps toward future body sensor networks integrated with IoT and AI. It compiles device examples and performance metrics while noting that direct stimulation using energy harvesters and neural interfaces remains at an infant level.
Key findings
- Wearable energy harvesters span piezoelectric, thermoelectric, and triboelectric mechanisms: a PZT nanocomposite generator produced 10 V and 1.3 µA for a 3 cm × 3 cm device under bending and 100 V and 10 µA for a 30 cm × 30 cm device under human motions; a PZT thin-film nanogenerator reached ∼200 V and ∼150 µA/cm²; a thermoelectric generator achieved 4.78 mW/cm² at a 25 °C temperature difference; and a stretchable TENG e-skin generated ∼1.16 mW/cm² at 2.3 Hz with up to 600% stretchability.
- Implantable harvesters demonstrated in vivo or organ-motion tests include a ZnO single-wire generator producing 3 mV and 30 pA from a live rat heartbeat, a PZT ribbon producing ∼4 V on a bovine heart, a PMN-PZT harvester producing 17.8 V and 1.75 µA from porcine heartbeat, an encapsulated iTENG producing 14 V and 5 µA with stability over 72 h, and an iTEAS producing ∼10 V and ∼4 µA from swine heartbeat and breathing.
- Biodegradable and 2D-material devices include a BD-TENG reaching ∼40 V and ∼1 µA, a gelatin/PLA TENG reaching 500 V, 10.6 mA/m², and 5 W/m² with complete degradation in water in about 40 days, monolayer MoS₂ generating 15 mV and 20 pA under 0.53% strain with 5.08% conversion efficiency, a MoS₂-enhanced TENG reaching 25.7 W/m² (120 times higher than without MoS₂), and a graphene TENG reaching 130 mW.
- Neural interfaces reviewed include flexible near-field wireless optoelectronic implants, syringe-implanted mesh electronics, flexible microneedle electrodes, e-dura spinal implants, cuff/FINE/TIME peripheral nerve interfaces, and neural dust; the review concludes that combining active neural interfaces with energy harvesting may construct an internal body sensor network.
Methods
- Design: narrative review of state-of-the-art wearable and implantable devices, from sensors and stimulators to energy harvesters, plus biodegradable and 2D-material-based devices.
- Data or sample: published literature and prior device demonstrations; no primary human or animal experiments reported by the review itself.
- Main analysis: qualitative synthesis and comparison of device mechanisms, materials, and reported performance metrics, with figures summarizing representative examples.
Limitations
- The paper states that direct stimulation using energy harvesters and neural interfaces is still at an infant level, that implantable batteries have limited capacity requiring replacement, and that rigid implant bodies cause mechanical mismatch with tissues.
- Evident from the text: this is a narrative review without a described systematic search strategy, inclusion/exclusion criteria, or quantitative meta-analysis; the paper does not state limitations of the review itself.
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Claims the paper makes
0 of 127 cited sources checked · 0 supported · 0 flagged
- Premisecitation
The significant transition from typical electronics to flexible electronics started with materials and mechanic and design strategies to match the epidermis.
“Significant transition from typical electronics to flexible electronics started with materials and mechanic and design strategies to match the epidermis.24,25”
Quote in the paperNot a substantial claim0 of 2 sources checked - Premisecitation
Wearable sweat sensors detect physiologically relevant information for non-invasive health monitoring.
“In addition, wearable sweat sensors detect physiologically relevant information for non-invasive health monitoring [Fig.1(c)]. 2”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [2] 2018, Nat. Electron. source
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- Premisecitation
E-skin has demonstrated promising results for applications such as human-machine interface, prosthetics, and medicine.
“This e-skin has demonstrated promising results for various applications such as human-machine interface, prosthetics, and medicine.6”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [6] 2016, Nature source
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- Premisecitation
Energy harvesters with wearable and implantable forms scavenge human body energy into useful electrical energy.
“To power the wearable and implantable electronics sustainably, another research trend is to develop energy harvesters with wearable and implantable forms that scavenge human body energy into useful electrical energy.[12][13][14][15][16]”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [12][13][14][15][16]
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- Premisecitation
Advanced 2D materials and biodegradable materials are applied to implantable sensors and energy harvesters to meet requirements of smaller, lighter, higher capacity, and biocompatible materials.
“Advanced 2D materials as well as biodegradable materials are applied to implantable sensors and energy harvesters to meet these requirements.[20][21][22][23]”
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- Premisecitation
The fabricated PDMS-interface and dome-shaped PDMS enable matching with the curvature of the eye.
“The fabricated polydimethylsiloxane (PDMS)-interface and of the dome-shaped PDMS enable to match with the curvature of the eye [Fig.1(e)].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [33] 2018, Nat. Commun. source
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- Premisecitation
Combination of wearable energy harvesters and implantable neural interface enables direct modulation of muscle without battery.
“For instance, combination of wearable energy harvesters and implantable neural interface enable to directly modulate muscle without battery [Figs.1(f) and 1(g)].[17][18][19]”
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- Premisecitation
The rigid body of implantable devices and interface has the limitation of mechanical mismatch between the object and tissues, causing serious medical problems.
“Furthermore, the rigid body of implantable devices and interface has the limitation of mechanical mismatch between the object and tissues, causing serious medical problems.31”
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- Premisecitation
Flexible drug delivery microdevice (f-DDM) delivers timely drug administrations and maintenance of effective dose to maximize curing effects with minimal side effects.
“For instance, flexible drug delivery microdevice (f-DDM) delivers timely drug administrations and maintenance of effective dose to maximize curing effects with minimal side effects.32”
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- Premisecitation
A foldable and photovoltaic wide-field epiretinal prosthesis is developed, capable of stimulating wireless retinal ganglion cells.
“For instance, a foldable and photovoltaic wide-field epiretinal prosthesis is developed, capable of stimulating wireless retinal ganglion cells.33”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [33] 2018, Nat. Commun. source
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- Premisecitation
A flexible high-output nanogenerator based on piezoelectric ZnO nanowires on polyimide achieves an open circuit voltage of 2.03 V and a peak power density of ∼11 mW/cm3.
“The single layer device can achieve an open circuit voltage of 2.03 V and a peak power density of ∼11 mW/cm 3 , showing great potentials of using piezoelectric nanowire based generators for self-powered systems.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [39] 2010, Nano Lett. source
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- Premisecitation
A 3 cm × 3 cm PZT nanocomposite generator outputs 10 V and 1.3 μA under bending.
“The output voltage and current of a 3 cm × 3 cm generator are 10 V and 1.3 µA under bending, respectively.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [38] 2013, Adv. Energy Mater. source
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- Premisecitation
A flexible thermoelectric power generator using screen-printing and laser multiscanning lift-off consists of p-type Bi0.3Sb1.7Te3 and n-type Bi2Se0.3Te2.7 inorganic films.
“A flexible thermoelectric power generator is developed using screen-printing and laser multiscanning lift-off technique, which consists of p-type Bi 0.3 Sb 1.7 Te 3 inorganic film and n-type Bi 2 Se 0.3 Te 2.7 inorganic film [Fig.2(d)].48”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [48] 2016, ACS Nano source
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- Premisecitation
When 72 thermoelectric couples are connected in series, a power density of 4.78 mW/cm2 is achieved at a temperature difference of 25°C.
“When 72 thermoelectric couples (p-type and n-type) are connected in series, a power density of 4.78 mW/cm 2 can be achieved at a temperature difference of 25 • C.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [48] 2016, ACS Nano source
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- Premisecitation
A flexible piezoelectric nanocomposite generator using PZT particles achieves high output performance.
“As depicted in Fig. 2(a), a flexible piezoelectric nanocomposite generator is demonstrated by using Pb(Zr x Ti 1-x )O 3 (PZT) particles with excellent piezoelectricity to achieve high output performance.38”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [38] 2013, Adv. Energy Mater. source
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- Premisecitation
Piezoelectric PZT thin film can be fabricated on a flexible substrate through a large-area laser lift-off process.
“Piezoelectric PZT thin film can also be fabricated on a flexible substrate through a large-area laser lift-off (LLO) process [Fig.2(c)].46”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [46] 2014, Adv. Mater. source
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- Premisecitation
A larger 30 cm × 30 cm PZT nanocomposite generator outputs 100 V and 10 μA under human motions.
“Using a bar-coating technique, a larger generator of 30 cm × 30 cm can be fabricated with an output of 100 V and 10 µA under human motions.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [38] 2013, Adv. Energy Mater. source
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- Premisecitation
A wearable power-textile integrates fabric based TENG and fiber-shaped dye-sensitized solar cells to scavenge energy from human motions and solar light simultaneously.
“A wearable power-textile is demonstrated through the integration of fabric based TENG and fiber-shaped dye-sensitized solar cells (FDSSCs) to scavenge energy from human motions and solar light simultaneously [Fig.2(g)].67”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [67] 2016, Adv. Energy Mater. source
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- Interpretationcitation
Integrated energy harvesting and tactile sensing features enable the e-skin for a large variety of applications in robotics and self-sustainable systems.
“The integrated energy harvesting and tactile sensing features enables the e-skin for a large variety of applications in robotics and self-sustainable systems.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [54] 2014, Adv. Mater. source
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TENGs are widely adopted for energy harvesting and self-powered sensing due to simple device configuration/process, wide range of material choice, cost effectiveness, and high output performance.
“Due to the simple device configuration/process, wide range of material choice, cost effectiveness, and high output performance, TENGs are widely adopted for energy harvesting and self-powered sensing.”
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A maximum power density of ∼1.16 mW/cm2 can be generated from the energy harvesting skin at 2.3 Hz operation frequency.
“A maximum power density of ∼1.16 mW/cm 2 can be generated from the device at 2.3 Hz operation frequency.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [53] 2017, Nano Energy source
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- Premisecitation
The energy harvesting skin can be mounted on various body parts to scavenge diversified biomechanical energy from human motions.
“The energy harvesting skin can be mounted on various body parts (e.g., neck, arm, wrist, finger, palm, and foot.) to scavenge diversified biomechanical energy from human motions.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [53] 2017, Nano Energy source
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- Premisecitation
The e-skin harvests mechanical stimuli with an output of around tens of volts and tens of μA/cm2.
“Meanwhile, the e-skin is able to harvest mechanical stimuli with an output of around tens of volts and tens of µA/cm 2 .”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [54] 2014, Adv. Mater. source
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Capacitance change and film resistance change of the e-skin are measured simultaneously to detect and differentiate normal pressure, strain, or bending.
“In order to detect and differentiate normal pressure, strain, or bending, capacitance change and film resistance change of the e-skin are measured simultaneously.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [54] 2014, Adv. Mater. source
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- Premisecitation
The grating-structure TENG in the power-textile has an optimized power density of 0.32 mW/m2 under a 0.75 m/s sliding motion.
“The grating-structure TENG is fabricated by laser-scribing masking and Ni plating, with an optimized power density of 0.32 mW/m 2 under a 0.75 m/s sliding motion.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [67] 2016, Adv. Energy Mater. source
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- Premisecitation
An implantable ZnO single-wire generator is demonstrated to harvest biomechanical energy inside a rat.
“To harvest the biomechanical energy inside a rat, an implantable ZnO single-wire generator (SWG) is demonstrated [Fig.2(h)].69”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [69] 2010, Adv. Mater. source
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- Interpretationcitation
This research opens up the possibility to harvest biomechanical energy from the in vivo environment, e.g., heartbeat, muscle stretching, blood pressure, breath, and other vibrations.
“This research opens up the possibility to harvest the biomechanical energy from the in vivo environment, e.g., heartbeat, muscle stretching, blood pressure, breath, and other vibrations.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [69] 2010, Adv. Mater. source
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- Premisecitation
High-performance PMN-PZT thin film is developed with biocompatibility to enable in vivo self-powered wireless data transmission.
“Besides, high-performance piezoelectric thin film, i.e., (1 -x)Pb(Mg 1/3 Nb 2/3 )O 3 -(x)Pb(Zr,Ti)O 3 (PMN-PZT), is developed with biocompatibility to enable in vivo self-powered wireless data transmission [Fig.2(j)].71”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [71] 2017, Adv. Funct. Mater. source
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- Premisecitation
Triggered by the heartbeat motions of a live rat, the ZnO SWG generates an average voltage and current of 3 mV and 30 pA, respectively.
“Triggered by the heartbeat motions of a live rat, the SWG can generate an average voltage and current of 3 mV and 30 pA, respectively.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [69] 2010, Adv. Mater. source
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- Premisecitation
A piezoelectric energy harvester using PZT ribbon is reported for scavenging biomechanical energy from the motions of the heart, lung, and diaphragm.
“Another piezoelectric energy harvester using the PZT ribbon is reported for scavenging the biomechanical energy from the motions of the heart, lung, and diaphragm [Fig.2(i)].70”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [70] 2014, Proc. Natl. Acad. Sci. U. S. A. source
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Wireless data transmission powered by the porcine heartbeat driven energy harvester is successfully demonstrated.
“Due to the excellent output performance, wireless data transmission powered by the porcine heartbeat driven an energy harvester is successfully demonstrated.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [71] 2017, Adv. Funct. Mater. source
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- Premisecitation
When attached on a bovine heart, the PZT ribbon device produces an output voltage of around 4 V.
“When attached on a bovine heart, the device is able to produce an output voltage of around 4 V.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [70] 2014, Proc. Natl. Acad. Sci. U. S. A. source
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- Premisecitation
A miniaturized and broadband piezoelectric ultrasonic energy harvester based on a PZT diaphragm array is proposed as a reliable implantable energy source.
“A miniaturized and broadband piezoelectric ultrasonic energy harvester (PUEH) based on a PZT diaphragm array is proposed as a reliable implantable energy source [Fig.2(k)].85,86”
Quote in the paperSubstantial claim0 of 2 sources checked - Premisereasoning
TENGs are adopted for implantable energy harvesting after biocompatible and waterproof packaging.
“TENGs, due to the flexible nature and ultra-wide range of materials, are also adopted for implantable energy harvesting after biocompatible and waterproof packaging.”
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In an underwater test with 1 cm separation, output power density of the PUEH improved from 0.59 μW/cm2 to 3.75 μW/cm2 with frequency adjustment, when input ultrasound intensity is 1 mW/cm2.
“In the underwater test with 1 cm separation between the ultrasound transmitter and the PUEH, output power density can be improved from 0.59 µW/cm 2 to 3.75 µW/cm 2 with frequency adjustment, when the input ultrasound intensity is 1 mW/cm 2 .”
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Self-powered wireless transmission of electrical signals associated with the heartbeat is successfully achieved for real-time heartbeat monitoring.
“Because of the superior in vivo performance, self-powered wireless transmission of electrical signals associated with the heartbeat is successfully achieved for realtime heartbeat monitoring.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [76] 2016, ACS Nano source
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- Premisecitation
An encapsulated arc-shaped implantable TENG is reported for in vivo harvesting biomechanical energy from heartbeats.
“An encapsulated arc-shaped implantable TENG (iTENG) is reported for in vivo harvesting biomechanical energy from heartbeats [Fig.2(l)].76”
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- Premisecitation
Long-term stability of the iTENG is investigated by continuous output generation for over 72 h in an active animal model.
“Long-term stability of the iTENG is also investigated by continuous output generation for over 72 h in an active animal model.”
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- Premisecitation
Another TENG based self-powered implantable triboelectric active sensor is proposed to achieve in vivo continuous and real-time monitoring.
“In addition, another TENG based self-powered implantable triboelectric active sensor (iTEAS) is proposed to achieve in vivo continuous and real-time monitoring [Fig.2(m)].77”
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- Premisecitation
Adjusting ultrasound frequency within the broad bandwidth minimizes standing wave induced power loss for a wide range of implanted depths.
“Through adjusting ultrasound frequency within the broad bandwidth, standing wave induced power loss can be minimized for a wide range of implanted depths.”
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Energy delivery through acoustic energy transfer is a promising technique to enable more reliable and miniaturized implantable energy harvesters.
“Except for directly scavenging biomechanical energy from internal organ motions, energy delivery through acoustic energy transfer is another promising technique to enable more reliable and miniaturized implantable energy harvesters.”
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Shin et al. developed flexible near-field wireless optoelectronic implants for optogenetic control in a variety of behavioral apparatuses.
“For instance, Shin et al. developed flexible near-field wireless optoelectronic implants for optogenetic control in a variety of behavioral apparatuses [Fig.3(b)].93”
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- Premisecitation
The MEA such as an Utah array and Michigan probe implanted inside the brain investigated various neural characteristics of cortical and sensory areas in the brain.
“The MEA such as an Utah array and Michigan probe implanted inside the brain investigated various neural characteristics of cortical and sensory areas in the brain [Fig.3(a)].91,92”
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Bi-directional neuromodulation was achieved by combining ECoG recording and optical stimulation on small, freely behaving animals.
“Furthermore, bi-directional neuromodulation was achieved by combining ECoG recording and optical stimulation on small, freely behaving animals.94”
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- Premisecitation
The iTEAS is able to continuously monitor physiological and pathological signs, including heartbeat rate, respiratory rate, and arrhythmia.
“In addition, the iTEAS is able to continuously monitor the physiological and pathological signs, including heartbeat rate, respiratory rate, and arrhythmia.”
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- Premisecitation
Syringe-implanted mesh electronics showed stable long-term mapping and modulation of brain activity at the single-neuron level.
“Syringe-implanted mesh electronics showed stable long-term mapping and modulation of brain activity at the single-neuron level [Fig.3(c)].95”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [95] 2017, Curr. Opin. Neurobiol. source
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Flexible microneedle electrodes enabled attachment to a curved surface of rat brain to provide recording capability.
“In addition, flexible microneedle electrodes enabled to attach a curved surface of rat brain to provide recording capability [Fig.3(d)].96”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [96] 2016, Microsyst. Nanoeng. source
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- Premisecitation
A neural dust mote was suggested and demonstrated for neural recording of a sciatic nerve in an anesthetized rat using an ultrasound approach.
“For instance, a neural dust was suggested and demonstrated for neural recording of a sciatic nerve in an anesthetized rat using an ultrasound approach [Fig.4(g)].105”
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- Premisecitation
Neural signals from the glossopharyngeal and vagus nerves were chronically recorded using carbon nanotube yarn electrodes.
“In addition, neural signals from the glossopharyngeal and vagus nerves were chronically recorded using carbon nanotube (CNT) yarn electrodes [Fig.4(i)].109”
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An advanced form of carbon nanotube fibers-laden devices was implanted on the tracheal syringeal nerve for recording.
“An advanced form of carbon nanotube fibers (CNTfs)-laden devices was implanted on the tracheal syringeal nerve for recording.5”
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- Interpretationcitation
Neuromodulation does not need to be a confined electrical approach and can be applied using a variety of energies.
“This shows that neuromodulation does not need to be a confined electrical approach and can be applied using a variety of energies.”
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A magnetic approach was developed to stimulate neurons with less energy.
“A magnetic approach was developed to stimulate neurons with less energy as well.98”
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- Premisecitation
By stimulating or modulating peripheral neural signals, bioelectronics enables control of bodily functions or treatment of diseases.
“By stimulating or modulating peripheral neural signals, bioelectronics enables us to control bodily functions or treat diseases.”
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Another biodegradable TENG with a multilayer structure of biodegradable polymers and resorbable metals is proposed for short-term implantable energy harvesting.
“Another biodegradable TENG (BD-TENG) with multilayer structure of biodegradable polymers and resorbable metals is proposed for short-term implantable energy harvesting [Fig.5(b)].114”
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- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
The water-soluble property of the composite film can be controlled with glycerol content for up to two days lifetime.
“The water-soluble property of the composite film can be controlled with the glycerol content for up to two days lifetime.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [113] 2015, Nano Energy source
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- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
Over the past few years, a few energy harvesters have been demonstrated with great biodegradability for implantable applications.
“Over the past few years, a few energy harvesters have been demonstrated with great biodegradability for implantable applications.[113][114][115][116][117][118]”
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- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
A biodegradable nanogenerator is demonstrated using lead-free piezoelectric nanoparticles and silk fibroin composite for powering implantable devices.
“For example, a biodegradable nanogenerator is demonstrated using leadfree piezoelectric nanoparticles and silk fibroin composite for powering implantable devices [Fig.5(a)].113”
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- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
A wireless neural clip achieved wireless modulation of bladder functions.
“In addition, a wireless neural clip achieved wireless modulation of bladder functions [Fig.4(k)].7”
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- Premisecitation
Recently one research trend of the neural interface is to combine with neural tissue or biodegradable materials for long-term use or removing additional surgery.
“Novel approaches were demonstrated previously, and recently one of the research trends of the neural interface is to combine with neural tissue or biodegradable materials for long-term use or removing additional surgery.21,111,112”
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Microchannels were implanted on the dorsal surface of the S1-S2 spinal cord for feedback control of bladder functions.
“Microchannels were implanted on the dorsal surface of the S1-S2 spinal cord for feedback control of bladder functions [Fig.4(j)] 110”
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After completion of the working cycle, the BD-TENG is able to be degraded and resorbed inside the animal body without causing any adverse long-term effects.
“After completion of the working cycle, the BD-TENG is able to be degraded and resorbed inside the animal body without causing any adverse long-term effects.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [114] 2016, Sci. Adv. source
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- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
When egg white and rice paper are adopted as triboelectric materials, the fabricated TENG can produce a maximum voltage, current, and power density of 55 V, 0.6 μA, and 21.6 mW/m2, respectively.
“When egg white (EW) and rice paper (RP) are adopted as triboelectric materials, the fabricated TENG can produce a maximum voltage, current, and power density of 55 V, 0.6 µA, and 21.6 mW/m 2 , respectively.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [115] 2018, Adv. Mater. source
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- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
The positions of five natural materials in the triboelectric series are measured and ranked, providing guidance for material selection of biodegradable TENGs.
“The positions of the five natural materials in “triboelectric series” are measured and ranked, providing guidance for material selection of biodegradable TENGs.”
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- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
Through adopting different materials, tunable output performance and degradation lifetime can be achieved for the BD-TENG.
“Through adopting different materials, tunable output performance and degradation lifetime can be achieved.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [114] 2016, Sci. Adv. source
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- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
Various natural materials with complete bioabsorbability are investigated as triboelectric materials for biodegradable TENGs.
“As depicted in Fig. 5(c), various natural materials with complete bioabsorbability are investigated as the triboelectric materials for biodegradable TENGs.115”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [115] 2018, Adv. Mater. source
Not checked in the free run.
- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
A fully biodegradable TENG is demonstrated using a gelatin film and electrospun polylactic acid nanofiber as the triboelectric materials.
“Another fully biodegradable TENG is demonstrated using a gelatin film and electrospun polylactic acid (PLA) nanofiber as the triboelectric materials [Fig.5(d)].116”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [116] 2018, Nano Energy source
Not checked in the free run.
- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
After modification of the silk fibroin encapsulation film, the operation lifetime can be tuned from days to weeks.
“After modification of the silk fibroin encapsulation film, the operation lifetime can be tuned from days to weeks.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [115] 2018, Adv. Mater. source
Not checked in the free run.
- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
Biodegradable characterization of the device shows that all the materials can be completely degraded in water for about 40 days.
“The biodegradable characterization of the device shows that all the materials can be completely degraded in water for about 40 days.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [116] 2018, Nano Energy source
Not checked in the free run.
- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
- Premisecitation
Various piezoelectric, thermoelectric, and triboelectric energy harvesters have been developed based on emerging 2D materials such as MoS2, graphene, and black phosphorus.
“Various piezoelectric, thermoelectric, and triboelectric energy harvesters have been developed based on the emerging 2D materials, such as MoS 2 , 119-123 graphene, 41,[124][125][126][127][128] and black phosphorus.129”
Quote in the paperNot a substantial claim0 of 7 sources checked- cites [119] 2016, Adv. Funct. Mater. source
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- cites [120] 2014, Nature source
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- cites [121] 2016, Nano Energy source
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- cites [122] 2017, Semicond. Sci. Technol. source
Not checked in the free run.
- cites [123] 2017, ACS Nano source
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- cites 41,[124][125][126][127][128]
Not checked in the free run.
- cites [129] 2018, Adv. Energy Mater. source
Not checked in the free run.
- Premisecitation
In 2014, the piezoelectric property of MoS2 was first reported with experimental measurements showing that output can be generated from cyclic stretching and releasing of MoS2 flake with an odd number of atomic layers but not an even number.
“In 2014, the piezoelectric property of MoS 2 is first reported with experimental measurements showing that output can be generated from the cyclic stretching and releasing of MoS 2 flake with an odd number of atomic layers but not an even number of atomic layers [Fig.6(a)].120”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [120] 2014, Nature source
Not checked in the free run.
- Premisecitation
The piezoelectric coefficient d11 of CVD-grown monolayer MoS2 exhibits different values along different directions, 3.78 pm/V along the armchair direction and 1.38 pm/V along the zigzag direction.
“The experimental results show that the piezoelectric coefficient (d11) exhibits different values along different directions, 3.78 pm/V along the armchair direction and 1.38 pm/V along the zigzag direction.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [121] 2016, Nano Energy source
Not checked in the free run.
- Premisecitation
MoS2 can be adopted to enhance the output performance of a TENG.
“MoS 2 can also be adopted to enhance the output performance of TENG as shown in Fig. 6(c), where a monolayer MoS 2 is introduced in the negative friction layer as a triboelectric electron acceptor layer.123”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [123] 2017, ACS Nano source
Not checked in the free run.
- Premisecitation
The nanogenerator based on a MoS2/graphene nanocomposite exhibits improved thermoelectric performance compared to one based only on graphene or MoS2.
“The nanogenerator based on MoS 2 /graphene nanocomposite exhibits improved thermoelectric performance compared to that only based on graphene or MoS2.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [122] 2017, Semicond. Sci. Technol. source
Not checked in the free run.
- Premisecitation
A thermoelectric nanogenerator using a MoS2/graphene nanocomposite has been developed for thermal energy harvesting and temperature sensing.
“Furthermore, the thermoelectric nanogenerator using MoS 2 /graphene nanocomposite is developed for thermal energy harvesting and temperature sensing.122”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [122] 2017, Semicond. Sci. Technol. source
Not checked in the free run.
- Premisecitation
A single monolayer MoS2 flake can generate a peak output voltage of 15 mV and a current of 20 pA under 0.53% strain.
“A single monolayer MoS 2 flake can generate a peak output voltage of 15 mV and a current of 20 pA under 0.53% strain.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [120] 2014, Nature source
Not checked in the free run.
- Premisereasoning
The developed flexible piezoelectric nanogenerator with MoS2 in the armchair direction shows about two times higher output performance than that with MoS2 in the zigzag direction under the same strain.
“Correspondingly, the developed flexible piezoelectric nanogenerator with MoS 2 in the armchair direction shows about two times higher output performance than that with MoS 2 in the zigzag direction under the same strain.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [121] 2016, Nano Energy source
Not checked in the free run.
- Premisecitation
The unique directional dependent piezoelectric effect of CVD-grown monolayer MoS2 flake was investigated.
“Later on, the unique directional dependent piezoelectric effect of chemical vapor deposition (CVD)-grown monolayer MoS 2 flake is investigated [Fig.6(b)].121”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [121] 2016, Nano Energy source
Not checked in the free run.
- Interpretationreasoning
The great enhancement of the triboelectric output performance is due to the efficient capture of triboelectric electrons in the MoS2 layer.
“The great enhancement of the triboelectric output performance is due to the efficient capture of triboelectric electrons in the MoS 2 layer.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [123] 2017, ACS Nano source
Not checked in the free run.
- Premisenone given
For randomly stacked graphene TENG, the generated voltage and current density decrease with the number of layers.
“For randomly stacked graphene TENG, the generated voltage and current density decrease with the number of layers.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [126] 2014, Adv. Mater. source
Not checked in the free run.
- Premisecitation
With an optimized nanostructured and fluorinated treatment, the peak output power of the device can be increased to 130 mW.
“With an optimized nanostructured and fluorinated treatment, the peak output power of the device can be increased to 130 mW.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [124] 2016, Nano Energy source
Not checked in the free run.
- May combine two claims. 34
- Classified as probably not a substantial claim. 10
May combine two claims.
PremisecitationAdvanced bioelectronics with flexible and soft platforms are developed to record biological signals and to stimulate and control organs or nervous systems.
“For instance, advanced bioelectronics with flexible and soft platforms are developed not only to record biological signals but also to stimulate and control the organs or the nervous systems.[5][6][7][8]”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [5][6][7][8]
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
InterpretationreasoningThe information recorded by wearable electronics allows people to check their body condition and accumulate physiological information, improving the quality of daily life.
“The information allows people not only to check their body condition but also to accumulate physiological information, improving the quality of daily life.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationWearable and stretchable electronics can be affixed anywhere in the body and record information such as body temperature, heart rate, and blood pressure.
“For instance, wearable and stretchable electronics can be affixed anywhere in the body and record information such as body temperature, heart rate, and blood pressure.[1][2][3][4]”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [1][2][3][4]
Not checked in the free run.
May combine two claims.
Premisenone givenFlexible electronics technology enables sensors to stick on the human skin or to be implanted inside the human body.
“Flexible electronics technology enables sensors to stick on the human skin or to implant inside the human body.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationnone givenFlexible and soft electronics transform bulky and packaged biomedical devices into implantable and biocompatible devices, showing promising prospects for clinical applications.
“Furthermore, flexible and soft electronics transform bulky and packaged biomedical devices into implantable and biocompatible devices, showing promising prospects for clinical applications.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationA soft, conformal class of device records physiological mechano-acoustic signals from the skin and is capable of heart murmur detection in cardiac patients for advanced clinical diagnostics.
“Furthermore, a soft, conformal class of device records physiological mechano-acoustic signals from the skin, capable of heart murmur detection in a series of cardiac patients for advanced clinical diagnostics [Fig.1(b)].27”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [27] 2016, Sci. Adv. source
Not checked in the free run.
May combine two claims.
PremisecitationThese devices have the capability of mimicking the skin's ability to sense and generate biomimetic signals, which can be embedded on robotic systems.
“These devices have capability of mimicking the skin's ability to sense and generate biomimetic signals, which can be embedded on robotic systems [Fig.1(a)].26”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [26] 2016, Nat. Mater. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationFlexible and soft neural prostheses provide connection between the human nervous systems and devices or robotic systems to replace or enhance sensory, motor, and cognitive modalities.
“Flexible and soft neural prostheses provide connection between the human nervous systems and devices or robotic systems to replace or enhance sensory, motor, and cognitive modalities of the human.[9][10][11]”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [9][10][11]
Not checked in the free run.
May combine two claims.
InterpretationreasoningWearable and implantable energy harvesters may overcome critical challenges of reliable light-weight power sources, bulky size of bioelectronics, and additional external electronics for closed-loop systems.
“This may overcome the next critical challenges from the aspect of sustainable and long-term use of such devices: (i) reliable light-weight power source with sound output power; (ii) bulky size of bioelectronics when the implants integrate with many active components (such as amplifiers for neural recording and stimulators for neural stimulation); and (iii) additional electronics placed outside the”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationThese devices can be used as sensors or energy sources to stimulate organs or the nervous system.
“Furthermore, these devices can be used as sensors or energy sources to stimulate organs or the nervous system.[17][18][19]”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [17][18][19]
Not checked in the free run.
May combine two claims.
Premisecitationf-DDM wirelessly receives power and is flexible enough to be implantable on the curved cerebral cortex, delivering two different chemicals or prevention of seizure activity using an anti-epileptic drug.
“This device wirelessly receives power and is flexible enough to be implantable on the curved cerebral cortex, delivering two different chemicals or prevention of seizure activity using an anti-epileptic drug [Fig.1(d)].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [32] 2018, Nano Energy source
Not checked in the free run.
May combine two claims.
PremisereasoningAdvances in flexible and soft electronics enable conformal interface with soft tissue, organ, and muscles, providing several strategies of therapeutic effect.
“Advances in flexible and soft electronics enable conformal interface with soft tissue, organ, and muscles, providing several strategies of therapeutic effect.”
Quote in the paperSubstantial claimMay combine two claims.
Premisenone givenImplantable devices have limited battery capacity that requires replacement, making patient burden in terms of cost and the risk of surgery.
“Those have still been used in clinical trials, but there is still limited battery capacity that requires to be replaced, making patient burden in terms of cost and the risk of surgery.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationA pacemaker is invented and implanted in the human body to support heart function.
“For instance, a pacemaker is invented and implanted in the human body to support heart function.28”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [28] 2006, Images Paediatr. Cardiol.
Not checked in the free run.
May combine two claims.
PremisecitationPhotosynthetic bioelectronic sensors are developed to sense touch stimuli and low-intensity ultraviolet radiation and generate electrical power toward self-powered E-skin.
“In addition, photosynthetic bioelectronic sensors are developed to show that the ability to sense not only touch stimuli but also lowintensity ultraviolet radiation and generate an electrical power toward self-powered E-skin.34”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [34] 2018, Adv. Mater. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationDeep brain stimulation is suggested and demonstrated to activate or inhibit brain signals for neurological diseases such as Parkinson's disease, essential tremor, dystonia, chronic pain, and major depression.
“Also, deep brain stimulation (DBS) is suggested and demonstrated to activate or inhibit brain signals for neurological disease such as Parkinson's disease, essential tremor, dystonia, chronic pain, and major depression.29,30”
Quote in the paperNot a substantial claim0 of 2 sources checkedMay combine two claims.
PremisecitationA biological-cells-inspired energy harvesting skin based on a soft and stretchable TENG has cellular structures of physiological saline interconnected and encapsulated by soft silicone rubber, with stretchability up to 600%.
“The cellular structures of physiological saline (electrode) are interconnected and encapsulated by soft silicone rubber (triboelectric layer), with an ultrahigh stretchability of up to 600%.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [53] 2017, Nano Energy source
Not checked in the free run.
May combine two claims.
PremisecitationAnother stretchable electronic skin is proposed to detect and harvest various mechanical stimuli, and was the first stretchable energy harvesting e-skin at the time.
“Another stretchable electronic skin (e-skin) is proposed to detect and harvest various mechanical stimuli, which is the first stretchable energy harvesting e-skin at the time [Fig.2(f)].54”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [54] 2014, Adv. Mater. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisereasoningFabric or textile based TENGs are developing rapidly due to their wearable, lightweight, washable, and breathable natures.
“Recently, fabric or textile based TENGs are developing rapidly due to their unique natures of wearable, lightweight, washable, and breathable.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationTriggered by porcine heartbeat motions, the PMN-PZT energy harvester generates an open-circuit voltage and short-circuit current of 17.8 V and 1.75 μA, higher by a factor of 4.45 and 17.5 than previously reported in vivo piezoelectric energy harvesters.
“Triggered by porcine heartbeat motions, the energy harvester can generate an open-circuit voltage and short-circuit current of 17.8 V and 1.75 µA (higher by a factor of 4.45 and 17.5 than previously reported in vivo piezoelectric energy harvesters), respectively.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [71] 2017, Adv. Funct. Mater. source
Not checked in the free run.
May combine two claims.
PremisecitationThe FDSSCs in the power-textile achieve average power conversion efficiency, open circuit voltage, and short circuit current density of 6%, 0.6 V, and 10.6 mA/cm2, respectively.
“At the same time, the FDSSCs can achieve an average power conversion efficiency, open circuit voltage, and short circuit current density of 6%, 0.6 V, and 10.6 mA/cm 2 , respectively.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [67] 2016, Adv. Energy Mater. source
Not checked in the free run.
May combine two claims.
PremisecitationDriven by porcine heartbeats, the iTENG generates an open circuit voltage of 14 V and a short circuit current of 5 μA.
“Driven by porcine heartbeats, the iTENG can generate an open circuit voltage of 14 V and a short circuit current of 5 µA.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [76] 2016, ACS Nano source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationNeural signals from the brain have been used in applications ranging from medical to engineering fields, such as epilepsy surgery using ECoG and brain computer interface applications using EEG.
“Such signals were used in various applications ranging from medical to engineering fields, such as an epilepsy surgery using ECoG 88 and brain computer interface applications using EEG.89,90”
Quote in the paperNot a substantial claim0 of 3 sources checkedProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based). May combine two claims.
Premisenone givenAdvances in flexible and soft electronics have allowed neural interfaces to better adapt to soft tissue and to apply to a variety of platforms like optoelectronic based interfaces.
“Advances in flexible and soft electronics have allowed neural interfaces to better adapt to soft tissue as well as to apply to a variety of platforms like optoelectronic based interfaces.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationDue to limitations of EEG and ECoG that cannot obtain signals inside the brain, multi-electrode arrays were designed and demonstrated to be implanted inside the brain using MEMS technologies.
“Due to the limitations of EEG and ECoG that cannot obtain signals inside the brain, 91 multi-electrode arrays (MEAs) were designed and demonstrated to be implanted inside the brain using microelectromechanical systems (MEMS) technologies.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [91] 2014, Adv. Mater. source
Not checked in the free run.
May combine two claims.
PremisecitationDriven by the heartbeat and breathing motions of a living swine, the iTEAS produces an open circuit voltage of ∼10 V and a short circuit current of ∼4 μA.
“Driven by the heartbeat and breathing motions of a living swine, the iTEAS can produce an open circuit voltage of ∼10 V and a short circuit current of ∼4 µA.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [77] 2016, Nano Lett. source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationE-dura implant was developed to insert in the spinal subdural space of rats.
“E-dura implant was also developed to insert in the spinal subdural space of rats [Fig.3(e)].97”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [97] 2015, Science source
Not checked in the free run.
May combine two claims.
PremisecitationA wireless cuff was suggested, combining reliable cuff interface and mid-field transfer, and modulated a vagus nerve to control heart functions.
“Accordingly, a wireless cuff was suggested, combining reliable cuff interface and mid-field transfer.This modulated a vagus nerve to control heart functions [Fig.4(h)].108”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [108] 2017, PLoS One source
Not checked in the free run.
May combine two claims.
PremisecitationAdvanced neuroprostheses require neural interfaces capable of high quality recording from efferent signals to record intention of movements and reliable stimulation to provide sensory feedback to the brain.
“For instance, advanced neuroprostheses require neural interfaces capable of the high quality of recording from efferent signals to record intention of any movements as well as capable of reliable stimulation to provide sensory feedback to the brain.99,100”
Quote in the paperNot a substantial claim0 of 2 sources checkedMay combine two claims.
PremisecitationAg nanowires and polyvinylpyrrolidone are added to the nanoparticle-silk composite to enhance dispersion of nanoparticles and prevent Ag nanowires from connecting.
“Ag nanowires and polyvinylpyrrolidone are also added to the nanoparticle-silk composite, with the function of enhancing the dispersion of the nanoparticles and preventing Ag nanowires from connecting, respectively.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [113] 2015, Nano Energy source
Not checked in the free run.
- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
May combine two claims.
PremisecitationTriggered by a foot stepping motion, the biodegradable nanogenerator achieves a maximum output voltage of 2.2 V and a current density of 0.12 μA/cm2.
“Triggered by a foot stepping motion, a maximum output voltage of 2.2 V and a current density of 0.12 µA/cm 2 can be achieved.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [113] 2015, Nano Energy source
Not checked in the free run.
- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
May combine two claims.
PremisecitationThe open circuit voltage and short circuit current of the BD-TENG can reach up to ∼40 V and ∼1 μA, respectively.
“The open circuit voltage and short circuit current of the BD-TENG can reach up to ∼40 V and ∼1 µA, respectively.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [114] 2016, Sci. Adv. source
Not checked in the free run.
- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
Probably not a substantial claim: may not pass S3 (load-bearing).
Premisenone givenRecently, two-dimensional materials have attracted increasing research effort due to their unique property of a single layer of atoms.
“Recently, two-dimensional (2D) materials have attracted increasing research effort due to their unique property of a single layer of atoms.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationSingle-layer MoS2 has a strong intrinsic piezoelectric response because of broken inversion symmetry, while bilayers and bulk crystals are non-piezoelectric due to the centrosymmetric structure.
“The results indicate that single-layer MoS 2 has strong intrinsic piezoelectric response because of the broken inversion symmetry, while the bilayers and bulk crystals are non-piezoelectric due to the centrosymmetric structure.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [120] 2014, Nature source
Not checked in the free run.
May combine two claims.
PremisecitationThrough optimizing the contact surfaces and thickness of the gelatin and PLA films, a maximum output voltage, short circuit current density, and power density of 500 V, 10.6 mA/m2, and 5 W/m2 can be achieved with a device size of 4 cm × 4 cm.
“Through optimizing the contact surfaces and thickness of the gelatin and PLA films, a maximum output voltage, short circuit current density, and power density of 500 V, 10.6 mA/m 2 , and 5 W/m 2 can be achieved, respectively, with a device size of 4 cm × 4 cm.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [116] 2018, Nano Energy source
Not checked in the free run.
- Rests on an assumption: Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
May combine two claims.
PremisecitationThe corresponding power density and mechanical-to-electrical energy conversion efficiency are 2 mW/m2 and 5.08%, respectively.
“The corresponding power density and the mechanical-to-electrical energy conversion efficiency are 2 mW/m 2 and 5.08%, respectively.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [120] 2014, Nature source
Not checked in the free run.
May combine two claims.
PremisereasoningThe fabricated TENG with the MoS2 layer can produce a peak power density up to 25.7 W/m2, which is 120 times higher than that without the MoS2 layer.
“As a result, the fabricated TENG with the MoS 2 layer can produce a peak power density up to 25.7 W/m 2 , which is 120 times higher than that without the MoS 2 layer.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [123] 2017, ACS Nano source
Not checked in the free run.
May combine two claims.
PremisecitationUnder a temperature gradient of -35 K, the MoS2/graphene based nanogenerator can generate an output voltage of -0.73 mV and a power density of 8.8 nW/cm2.
“Under a temperature gradient of -35 K, the MoS 2 /graphene based nanogenerator can generate an output voltage of -0.73 mV and a power density of 8.8 nW/cm 2 .”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [122] 2017, Semicond. Sci. Technol. source
Not checked in the free run.
May combine two claims.
PremisecitationThe TENG with monolayer (1L) graphene can produce a voltage of 5 V and a current density of 500 nA/cm2.
“The TENG with monolayer (1L) graphene can produce a voltage of 5 V and a current density of 500 nA/cm 2 .”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [126] 2014, Adv. Mater. source
Not checked in the free run.
Classified as probably not a substantial claim.
InterpretationreasoningUsing diversified flexible electronics can create sensors, actuators, stimulators, energy harvesters, and/or integrated systems, for wide applications ranging from wearable to implantable electronics.
“From the research trends of flexible electronics technology, using diversified flexible electronics can create sensors, actuators, stimulators, energy harvesters, and/or integrated systems, for wide applications ranging from wearable to implantable electronics.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationFor regularly stacked graphene TENG, the generated voltage and current density can be increased to 9 V and 1.2 μA/cm2, respectively.
“For regularly stacked graphene TENG, the generated voltage and current density can be increased to 9 V and 1.2 µA/cm 2 , respectively.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [126] 2014, Adv. Mater. source
Not checked in the free run.
May combine two claims.
PremisecitationA conformal graphene based TENG is demonstrated with a total thickness of less than 2.4 mm and good adhesion ability on the human skin.
“A conformal graphene based TENG is demonstrated with a total thickness of less than 2.4 mm and good adhesion ability on the human skin [Fig.6(d)].124”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [124] 2016, Nano Energy source
Not checked in the free run.
The paper relies on this without support.
Biodegradability is of great importance for implantable energy harvesters, especially in short-term applications where no further surgical procedure is required to remove the implantable device.
“For implantable energy harvesters, biodegradability is of great importance especially in short-term application where no further surgical procedure is required to take out the implantable devices.”
The paper relies on this without support.
The brain is not fully understood and is a research area that needs further exploration.
“Despite of extensive research on the brain, the mystery of the brain has not yet been fully understood, and it is a research area that needs to be further explored.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Implantable sensors are designed to interact with biological components for support and treatment of bodily functions and mental health monitoring.
“Implantable sensors represent a frontier in healthcare, designed to interact with biological components for support and treatment of bodily functions and mental health monitoring [245,246].”
From The emergence of AI-based wearable sensors for digital health technology: a review (2023) · cites this paper as [245]
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Selective stimulation and neural recording on peripheral nerves using flexible split ring electrodes
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Flagged first, then by citations
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Cited by
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Triboelectric nanogenerator sensors for soft robotics aiming at digital twin applications
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Self-citationTemperature and Strain Compensation for Flexible Sensors Based on Thermosensation
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- Authors
- Lee, S., Shi, Q., & Lee, C.
- Affiliations
- National University of Singapore (SG)
- Corresponding author
- Lee, Chengkuo
- Venue
- APL Materials
- Publisher
- AIP Publishing
- Published
- 2019-02-06
- Volume
- 7
- Issue
- 3
- ISSN
- 2166-532X (ISSN-L)
- OpenAlex
- W2912990980
- Cited by
- 164
- References
- 129
- Citations by year
- 2026: 10 · 2025: 18 · 2024: 16 · 2023: 16 · 2022: 38 · 2021: 22 · 2020: 30 · 2019: 14
- FWCI
- 9.18
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- APL Materials (publishedVersion, cc-by)
- National University of Singapore (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- A*STAR and NCBR Joint Grant (R-263-000-C91-305)
- DGIST Start-up Fund (ICT 2018090020)
- Faculty Research Committee Singapore (R-263-000-B56-112)
- NUS HiFES (R-263-501-012-133)
- National Research Foundation Singapore (NRF-CRP10-2012-01, NRF-CRP8-2011-01)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Physical Sciences › Engineering › Biomedical Engineering › Wireless Body Area Networks
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Keywords
- flexible electronics, wearable sensors, implantable sensors, wireless body area networks, energy harvesting, mechanical energy conversion, thermal energy conversion, implant materials, biological signals, Internet of Things, artificial intelligence
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