The β4 nicotinic receptor subunit modulates the chronic antidepressant effect mediated by bupropion

Assessing antidepressant activity in rodents: recent developments and future needs

Cryan, J. F., Markou, A., & Lucki, I. (2002) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(02)02017-5 · Cited by 1,551 · see citing works

Brain nicotinic acetylcholine receptors: native subtypes and their relevance

Gotti, C., Zoli, M., & Clementi, F. (2006) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2006.07.004 · Cited by 882 · see citing works

Gender Differences in Treatment Response to Sertraline Versus Imipramine in Chronic Depression

Kornstein, S. G., Schatzberg, A. F., Thase, M. E., Yonkers, K. A., McCullough, J. P., Keitner, G. I., Gelenberg, A. J., Thomas, S., Harrison, W. M., & Keller, M. B. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.9.1445 · Cited by 712 · see citing works

Bupropion: a review of its mechanism of antidepressant activity.

Ascher, J. A., Cole, J. O., Colin, J. N., Feighner, J. P., Ferris, R. M., Fibiger, H. C., Golden, R. N., Martin, P., Potter, W. Z., & Richelson, E. (1995) · PubMed · Cited by 680 · see citing works

Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice

Salas, R., Sturm, R., Boulter, J., & De Biasi, M. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4934-08.2009 · Cited by 310 · see citing works

Nicotinic acetylcholine receptors as targets for antidepressants

Shytle, R. D., Silver, A. A., Lukas, R. J., Newman, M. B., Sheehan, D. V., & Sanberg, P. R. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001035 · Cited by 279 · see citing works

Sex Differences in Animal Models of Depression and Antidepressant Response

Dalla, C., Pitychoutis, P. M., Kokras, N., & Papadopoulou‐Daifoti, Z. (2009) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/j.1742-7843.2009.00516.x · Cited by 237 · see citing works

Decreased Signs of Nicotine Withdrawal in Mice Null for the β4 Nicotinic Acetylcholine Receptor Subunit

Salas, R., Pieri, F., & De Biasi, M. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1939-04.2004 · Cited by 226 · see citing works

Rodent Habenulo–Interpeduncular Pathway Expresses a Large Variety of Uncommon nAChR Subtypes, But Only the α3β4 and α3β3β4 Subtypes Mediate Acetylcholine Release

Grady, S. R., Moretti, M., Zoli, M., Marks, M. J., Zanardi, A., Pucci, L., Clementi, F., & Gotti, C. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.5121-08.2009 · Cited by 222 · see citing works

Enantioselective Effects of Hydroxy Metabolites of Bupropion on Behavior and on Function of Monoamine Transporters and Nicotinic Receptors

Damaj, M. I., Carroll, F. I., Eaton, J. B., Navarro, H. A., Blough, B. E., Mirza, S., Lukas, R. J., & Martin, B. R. (2004) · Molecular Pharmacology · doi:10.1124/mol.104.001313 · Cited by 212 · see citing works

Evidence for, and nature of, the tonic inhibitory influence of habenulointerpeduncular pathways upon cerebral dopaminergic transmission in the rat

Nishikawa, T., Fage, D., & Scatton, B. (1986) · Brain Research · doi:10.1016/0006-8993(86)90347-1 · Cited by 166 · see citing works

Pharmacokinetics of Bupropion and its Metabolites in Cigarette Smokers versus Nonsmokers

Hsyu, P., Singh, A. K., Giargiari, T. D., Dunn, J. A., Ascher, J. A., & Johnston, J. A. (1997) · The Journal of Clinical Pharmacology · doi:10.1002/j.1552-4604.1997.tb04361.x · Cited by 137 · see citing works

Involvement of nitric oxide (NO) signaling pathway in the antidepressant action of bupropion, a dopamine reuptake inhibitor

Dhir, A., & Kulkarni, S. K. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.04.028 · Cited by 133 · see citing works

Current Considerations in the Treatment of Generalized Anxiety Disorder

Katzman, M. A. (2009) · CNS Drugs · doi:10.2165/00023210-200923020-00002 · Cited by 128 · see citing works

Synthesis and Biological Evaluation of Bupropion Analogues as Potential Pharmacotherapies for Smoking Cessation

Carroll, F. I., Blough, B. E., Mascarella, S. W., Navarro, H. A., Eaton, J. B., Lukas, R. J., & Damaj, M. I. (2010) · Journal of Medicinal Chemistry · doi:10.1021/jm9017465 · Cited by 119 · see citing works

The α3 and β4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice

Salas, R., Cook, K. D., Bassetto, L., & De Biasi, M. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.05.002 · Cited by 115 · see citing works

Influence of Neuronal Nicotinic Receptors over Nicotine Addiction and Withdrawal

De Biasi, M., & Salas, R. (2008) · Experimental Biology and Medicine · doi:10.3181/0712-mr-355 · Cited by 95 · see citing works

Mice lacking neuronal nicotinic acetylcholine receptor β4-subunit and mice lacking both α5- and β4-subunits are highly resistant to nicotine-induced seizures

Kedmi, M., Beaudet, A. L., & Orr‐Urtreger, A. (2004) · Physiological Genomics · doi:10.1152/physiolgenomics.00202.2003 · Cited by 89 · see citing works

Effects of gender on relapse prevention in smokers treated with bupropion SR

Gonzales, D. H. (2002) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(02)00419-1 · Cited by 85 · see citing works

Is the inhibition of nicotinic acetylcholine receptors by bupropion involved in its clinical actions?

Arias, H. R. (2009) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2009.05.015 · Cited by 77 · see citing works

Single‐Dose Pharmacokinetics of Bupropion in Adolescents: Effects of Smoking Status and Gender

Stewart, J. J., Berkel, H. J., Parish, R. C., et al. (2001) · The Journal of Clinical Pharmacology · doi:10.1177/00912700122010564 · Cited by 75 · see citing works

Neuronal nicotinic receptors: insights gained from gene knockout an knocking mutant mice

Drago, J., McColl, C. D., Horne, M. K., Finkelstein, D. I., & Ross, S. A. (2003) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-2259-9 · Cited by 68 · see citing works

Regulation of acetylcholine receptor gene expression in human myasthenia gravis muscles. Evidences for a compensatory mechanism triggered by receptor loss.

Guyon, T., Wakkach, A., Poëa, S., et al. (1998) · Journal of Clinical Investigation · doi:10.1172/jci1248 · Cited by 67 · see citing works

Interaction of Bupropion with Muscle-Type Nicotinic Acetylcholine Receptors in Different Conformational States

Arias, H. R., Gumilar, F., Rosenberg, A., Targowska‐Duda, K. M., Feuerbach, D., Jóźwiak, K., Moaddel, R., Wainer, I. W., & Bouzat, C. (2009) · Biochemistry · doi:10.1021/bi802206k · Cited by 44 · see citing works

Bupropion and cognitive-behavioral therapy for smoking cessation in women

Schmitz, J. M., Stotts, A. L., Mooney, M. E., DeLaune, K. A., & Moeller, G. F. (2007) · Nicotine & Tobacco Research · doi:10.1080/14622200701365335 · Cited by 44 · see citing works

Pharmacological and Neurotoxicological Actions Mediated By Bupropion and Diethylpropion

Arias, H. R., Santamarı́a, A., & Ali, S. F. (2009) · International review of neurobiology · doi:10.1016/s0074-7742(09)88009-4 · Cited by 41 · see citing works

Neurochemical and behavioral effects elicited by bupropion and diethylpropion in rats

Santamarı́a, A., & Arias, H. R. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.03.023 · Cited by 41 · see citing works

Comparison of the effects of bupropion and nicotine on locomotor activation and dopamine release in vivo

Sidhpura, N., Redfern, P. H., Rowley, H. L., Heal, D. J., & Wonnacott, S. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.06.025 · Cited by 37 · see citing works

Tricyclic antidepressants and mecamylamine bind to different sites in the human α4β2 nicotinic receptor ion channel

Arias, H. R., Rosenberg, A., Targowska‐Duda, K. M., Feuerbach, D., Jóźwiak, K., Moaddel, R., & Wainer, I. W. (2010) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2010.03.002 · Cited by 35 · see citing works

Inhibitory mechanisms and binding site location for serotonin selective reuptake inhibitors on nicotinic acetylcholine receptors

Arias, H. R., Feuerbach, D., Bhumireddy, P., & Ortells, M. O. (2010) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2010.01.007 · Cited by 34 · see citing works

Review of the Use of Pattern Analysis to Differentiate True Drug and Placebo Responses

Rothschild, R., & Quitkin, F. M. (2010) · Psychotherapy and Psychosomatics · doi:10.1159/000288625 · Cited by 34 · see citing works

Different interaction between tricyclic antidepressants and mecamylamine with the human α3β4 nicotinic acetylcholine receptor ion channel

Arias, H. R., Targowska‐Duda, K. M., Feuerbach, D., Sullivan, C. J., Maciejewski, R., & Jóźwiak, K. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.01.011 · Cited by 33 · see citing works

Relative antidepressant efficacy of bupropion and the selective serotonin reuptake inhibitors in major depressive disorder: gender–age interactions

Papakostas, G. I., Kornstein, S. G., Clayton, A. H., Soares, C. N., Hallett, L. A., Krishen, A., & Tucker, V. L. (2007) · International Clinical Psychopharmacology · doi:10.1097/yic.0b013e32819f8400 · Cited by 32 · see citing works

The report of the National Advisory Mental Health Council

Pardes, H. (1993) · American Journal of Psychiatry · doi:10.1176/ajp.150.10.1445 · Cited by 30 · see citing works

Chronic effect of nicotine on serotonin transporter mRNA in the raphe nucleus of rats: Reversal by co‐administration of bupropion

Semba, J., & Wakuta, M. (2008) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2008.01822.x · Cited by 28 · see citing works

Molecular interaction of bupropion with nicotinic acetylcholine receptors

Arias, H. (2016) · Journal of Pediatric Biochemistry · doi:10.1055/s-0036-1586365 · Cited by 12 · see citing works

Mood and anxiety regulation by nicotinic acetylcholine receptors: A potential pathway to modulate aggression and related behavioral states

Picciotto, M. R., Lewis, A. S., van Schalkwyk, G. I., & Mineur, Y. S. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.12.028 · Cited by 157 · see citing works

Bupropion

Moser, P. (2008) · xPharm: The Comprehensive Pharmacology Reference · doi:10.1016/b978-008055232-3.64054-1

Studies of bupropion's mechanism of antidepressant activity.

Ferris, R. M., Cooper, B. R., & Maxwell, R. A. (1983) · PubMed · Cited by 127 · see citing works

Potential Nicotinic Acetylcholine Receptor Ligands from 2,4-Methanoproline Derivatives

Patel, A. B., & Malpass, J. R. (2008) · Journal of Medicinal Chemistry · doi:10.1021/jm800537a · Cited by 15 · see citing works

Apisα2, Apisα7-1 and Apisα7-2: three new neuronal nicotinic acetylcholine receptor α-subunits in the honeybee brain

Thany, S. H., Crozatier, M., Raymond, V., et al. (2004) · Gene · doi:10.1016/j.gene.2004.09.010 · Cited by 63 · see citing works

6-[18F]fluoro-A-85380: an in vivo tracer for the nicotinic acetylcholine receptor

Scheffel, U., Horti, A. G., Koren, A. O., Ravert, H. T., Banta, J. P., Finley, P. A., London, E. D., & Dannals, R. F. (2000) · Nuclear Medicine and Biology · doi:10.1016/s0969-8051(99)00082-7 · Cited by 87 · see citing works