Focused transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex modulates specific domains of self-regulation
Abstract
Recent neuroscience theories suggest that different kinds of self-regulation may share a common psychobiological mechanism. However, empirical evidence for a domain general self-regulation mechanism is scarce. The aim of this study was to investigate whether focused anodal transcranial direct current stimulation (tDCS), facilitating the activity of the dorsolateral prefrontal cortex (dlPFC), acts on a domain general self-regulation mechanism and thus modulates both affective and appetitive self-regulation. Twenty smokers participated in this within-subject sham controlled study. Effects of anodal left, anodal right and sham tDCS over the dlPFC on affective picture appraisal and nicotine craving-cue appraisal were assessed. Anodal right tDCS over the dlPFC reduced negative affect in emotion appraisal, but neither modulated regulation of positive emotion appraisal nor of craving appraisal. Anodal left stimulation did not induce any significant effects. The results of our study show that domain specific self-regulation networks are at work in the prefrontal cortex. Focused tDCS modulation of this specific self-regulation network could probably be used during the first phase of nicotine abstinence, during which negative affect might easily result in relapse. These findings have implications for neuroscience models of self-regulation and are of relevance for the development of brain stimulation based treatment methods for neuropsychiatric disorders associated with self-regulation…
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Anodal tDCS to the right DLPFC but not the left is correlated with greater cognitive control during emotional regulation, mainly with negative emotional images.
“Concomitantly, a more recent study by13 showed that anodal tDCS to the right DLPFC but not the left, is correlated with a greater cognitive control during emotional regulation, mainly with negative emotional images.”
From Ventrolateral but not Dorsolateral Prefrontal Cortex tDCS effectively impact emotion reappraisal – effects on Emotional Experience and Interbeat Interval (2018) · cites this paper as [13]
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Transcranial direct current stimulation during sleep improves declarative memory
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Transcranial Direct Current Stimulation Enhances Cognitive Control During Emotion Regulation
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Batista, E. K., Klauss, J., Fregni, F., Nitsche, M. A., & Nakamura-Palacios, E. M. (2015) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyv066 · Cited by 144 · see citing works
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- Authors
- Pripfl, J., & Lamm, C.
- Affiliations
- University of Vienna (AT)
- Corresponding author
- Pripfl, Jürgen
- Venue
- Neuroscience Research
- Publisher
- Elsevier BV
- Published
- 2015-02
- Volume
- 91
- Pages
- 41-47
- ISSN
- 0168-0102 (ISSN-L)
- OpenAlex
- W2010425691
- Cited by
- 45
- References
- 5
- Citations by year
- 2025: 4 · 2024: 5 · 2023: 2 · 2022: 5 · 2021: 8 · 2020: 2 · 2019: 8 · 2018: 2 · 2016: 7 · 2015: 2
- FWCI
- 1.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroscience Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- MMI-CNS research cluster
- Oesterreichische Nationalbank
- Topics
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Keywords
- transcranial direct current stimulation, dorsolateral prefrontal cortex, self-regulation, affective self-regulation, nicotine craving, negative affect, emotion appraisal, smoking, nicotine abstinence, domain specificity, neuromodulation
- MeSH terms
- Self-Control, Adult, Cues, Emotions, Humans, Photic Stimulation, Smoking, Prefrontal Cortex, Young Adult, Transcranial Direct Current Stimulation, Craving
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