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Cited by 692

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Patch-based segmentation using expert priors: Application to hippocampus and ventricle segmentation

Open access
Coupé, Pierrick, Manjón, José V., Fonov, Vladimir, Pruessner, Jens, Robles, Montserrat, Collins, D. Louis·2011·NeuroImage

Abstract

Quantitative magnetic resonance analysis often requires accurate, robust, and reliable automatic extraction of anatomical structures. Recently, template-warping methods incorporating a label fusion strategy have demonstrated high accuracy in segmenting cerebral structures. In this study, we propose a novel patch-based method using expert manual segmentations as priors to achieve this task. Inspired by recent work in image denoising, the proposed nonlocal patch-based label fusion produces accurate and robust segmentation. Validation with two different datasets is presented. In our experiments, the hippocampi of 80 healthy subjects and the lateral ventricles of 80 patients with Alzheimer's disease were segmented. The influence on segmentation accuracy of different parameters such as patch size and number of training subjects was also studied. A comparison with an appearance-based method and a template-based method was also carried out. The highest median kappa index values obtained with the proposed method were 0.884 for hippocampus segmentation and 0.959 for lateral ventricle segmentation.

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Metadata

Authors
Coupé, P., Manjón, J. V., Fonov, V., Pruessner, J., Robles, M., & Collins, D. L.
Venue
NeuroImage
Publisher
Elsevier BV
Published
2011-01
Volume
54
Issue
2
Pages
940-954
ISSN
1053-8119 (ISSN-L)
OpenAlex
W2010587020
Cited by
692
References
10
FWCI
32.43
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Patch-based segmentation using expert priors: Application to hippocampus and ventricle segmentation. https://app.cochat.ai/papers/10.1016/j.neuroimage.2010.09.018
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Coupé, P., Manjón, J. V., Fonov, V., Pruessner, J., Robles, M., & Collins, D. L. (2011). Patch-based segmentation using expert priors: Application to hippocampus and ventricle segmentation. NeuroImage. https://doi.org/10.1016/j.neuroimage.2010.09.018

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.