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The influence of head motion on intrinsic functional connectivity MRI
Open accessAbstract
Functional connectivity MRI (fcMRI) has been widely applied to explore group and individual differences. A confounding factor is head motion. Children move more than adults, older adults more than younger adults, and patients more than controls. Head motion varies considerably among individuals within the same population. Here we explored the influence of head motion on fcMRI estimates. Mean head displacement, maximum head displacement, the number of micro movements (>0.1 mm), and head rotation were estimated in 1000 healthy, young adult subjects each scanned for two resting-state runs on matched 3T scanners. The majority of fcMRI variation across subjects was not linked to head motion. However, head motion had significant, systematic effects on fcMRI network measures. Head motion was associated with decreased functional coupling in the default and frontoparietal control networks--two networks characterized by coupling among distributed regions of association cortex. Other network measures increased with motion including estimates of local functional coupling and coupling between left and right motor regions--a region pair sometimes used as a control in studies to establish specificity. Comparisons between groups of individuals with subtly different levels of head motion yielded difference maps that could be mistaken for neuronal effects in other contexts. These effects are important to consider when interpreting variation between groups and across individuals.
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“Strict motion correction procedures were applied to resting state functional maps, due to the sensitivity of RSFC data to head motion (Power et al., 2012, Satterthwaite et al., 2012, Van Dijk et al., 2012).”
From Developmental sex differences in resting state functional connectivity of amygdala sub-regions (2015) · cites this paper as Van Dijk et al., 2012
In the citing paper
“head motion has become a substantial concern since 2012 when a trio of papers pointed to systematic motion-related artifacts in rs-fcMRI (Power et al., 2012; Satterthwaite et al., 2012; Van Dijk et al., 2012).”
From Development of large-scale functional networks from birth to adulthood: A guide to the neuroimaging literature (2017) · cites this paper as Van Dijk et al., 2012
In the citing paper
“researchers recently discovered that some functional connectivity analyses interpreted as demonstrating developmental increases in long-range connections during rest (i.e., independent from any task) were spurious effects of greater motion in younger participants [62,63], which were eliminated with appropriate controls for motion-induced artifacts.”
From Arrested development? Reconsidering dual-systems models of brain function in adolescence and disorders (2012) · cites this paper as [63]
In the citing paper
“Head motion, even of submillimeter magnitude, has been identified as a nonphysiological source of spurious variance in resting-state fMRI data (Power et al. 2012; Van Dijk et al. 2012; Satterthwaite et al. 2013).”
From Joint attention and brain functional connectivity in infants and toddlers (2017) · cites this paper as Van Dijk et al. 2012
In the citing paper
“The strength of long-range functional connectivity is underestimated in cases of increased head motion (Van Dijk et al., 2012)”
From Investigating functional brain network integrity using a traditional and novel categorical scheme for neurodevelopmental disorders (2019) · cites this paper as Van Dijk et al., 2012
In the citing paper
“One important source of artifactual variation in functional MRI is head motion (47).”
From Understanding heterogeneity in clinical cohorts using normative models: Beyond case-control studies (2016) · cites this paper as [47]
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Cites
Baltosser, W. H., & Zar, J. H. (1996) · Ecology · doi:10.2307/2265725 · Cited by 35,166
A default mode of brain function
Raichle, M. E., MacLeod, A. M., Snyder, A. Z., Powers, W. J., Gusnard, D. A., & Shulman, G. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.98.2.676 · Cited by 12,190
Jenkinson, M., Bannister, P., Brady, M., & Smith, S. (2002) · NeuroImage · doi:10.1006/nimg.2002.1132 · Cited by 11,888
Complex network measures of brain connectivity: Uses and interpretations
Rubinov, M., & Sporns, O. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2009.10.003 · Cited by 11,522
Functional connectivity in the motor cortex of resting human brain using echo‐planar mri
Biswal, B., Zerrin Yetkin, F., Haughton, V. M., & Hyde, J. S. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910340409 · Cited by 9,812
The organization of the human cerebral cortex estimated by intrinsic functional connectivity
Thomas Yeo, B. T., Krienen, F. M., Sepulcre, J., Sabuncu, M. R., Lashkari, D., Hollinshead, M., Roffman, J. L., Smoller, J. W., Zöllei, L., Polimeni, J. R., et al. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00338.2011 · Cited by 9,182
Self-citationPower, J. D., Barnes, K. A., Snyder, A. Z., Schlaggar, B. L., & Petersen, S. E. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.10.018 · Cited by 7,429
The organization of the human cerebellum estimated by intrinsic functional connectivity
Buckner, R. L., Krienen, F. M., Castellanos, A., Diaz, J. C., & Yeo, B. T. T. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00339.2011 · Cited by 7,304
Self-citationDynamic magnetic resonance imaging of human brain activity during primary sensory stimulation.
Kwong, K. K., Belliveau, J. W., Chesler, D. A., Goldberg, I. E., Weisskoff, R. M., Poncelet, B. P., Kennedy, D. N., Hoppel, B. E., Cohen, M. S., & Turner, R. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.12.5675 · Cited by 4,212
Ogawa, S., Tank, D. W., Menon, R., Ellermann, J. M., Kim, S. G., Merkle, H., & Ugurbil, K. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.13.5951 · Cited by 3,681
Predicting human resting-state functional connectivity from structural connectivity
Honey, C. J., Sporns, O., Cammoun, L., Gigandet, X., Thiran, J. P., Meuli, R., & Hagmann, P. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811168106 · Cited by 3,307
Buckner, R. L., Sepulcre, J., Talukdar, T., Krienen, F. M., Liu, H., Hedden, T., Andrews-Hanna, J. R., Sperling, R. A., & Johnson, K. A. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.5062-08.2009 · Cited by 2,862
Self-citationEvidence for a Frontoparietal Control System Revealed by Intrinsic Functional Connectivity
Vincent, J. L., Kahn, I., Snyder, A. Z., Raichle, M. E., & Buckner, R. L. (2008) · Journal of Neurophysiology · doi:10.1152/jn.90355.2008 · Cited by 1,869
Self-citationVan Dijk, K. R. A., Hedden, T., Venkataraman, A., Evans, K. C., Lazar, S. W., & Buckner, R. L. (2010) · Journal of Neurophysiology · doi:10.1152/jn.00783.2009 · Cited by 1,844
Self-citationDisruption of Large-Scale Brain Systems in Advanced Aging
Andrews-Hanna, J. R., Snyder, A. Z., Vincent, J. L., Lustig, C., Head, D., Raichle, M. E., & Buckner, R. L. (2007) · Neuron · doi:10.1016/j.neuron.2007.10.038 · Cited by 1,592
Self-citation3D statistical neuroanatomical models from 305 MRI volumes
Evans, A. C., Collins, D. L., Mills, S., Brown, E. D., Kelly, R. L., & Peters, T. M. (2005) · IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) · doi:10.1109/nssmic.1993.373602 · Cited by 1,487
The oscillating brain: Complex and reliable
Zuo, X., Martino, A. D., Kelly, C. A. M., Shehzad, Z. E., Gee, D. G., Klein, D. F., Castellanos, F. X., Biswal, B. B., & Milham, M. P. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.09.037 · Cited by 1,466
Functional Magnetic Resonance Imaging
Walsh, A. (2014) · Encyclopedia of Criminal Justice Ethics · doi:10.4135/9781452274102.n135 · Cited by 1,225
Clinical applications of resting state functional connectivity
Fox, M. (2010) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2010.00019 · Cited by 1,219
Advances and pitfalls in the analysis and interpretation of resting-state FMRI data
Cole, D. M. (2010) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2010.00008 · Cited by 1,011
Coherent spontaneous activity identifies a hippocampal-parietal memory network
Vincent, J. L., Snyder, A. Z., Fox, M. D., Shannon, B. J., Andrews, J. R., Raichle, M. E., & Buckner, R. L. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00048.2006 · Cited by 959 · cited 1×
“See Vincent et al. (2006) and Van Dijk et al. (2010) for detailed descriptions of the above procedures.”
Self-citationThe Resting Brain: Unconstrained yet Reliable
Shehzad, Z. E., Kelly, C. A. M., Reiss, P. T., Gee, D. G., Gotimer, K., Uddin, L. Q., Lee, S. H., Margulies, D. S., Roy, A. K., Biswal, B. B., et al. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhn256 · Cited by 948
Disease and the brain's dark energy
Zhang, D., & Raichle, M. E. (2010) · Nature Reviews Neurology · doi:10.1038/nrneurol.2009.198 · Cited by 928
Influence of heart rate on the BOLD signal: The cardiac response function
Chang, C., Cunningham, J. P., & Glover, G. H. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.09.029 · Cited by 682
Birn, R. M., Smith, M. A., Jones, T. B., & Bandettini, P. A. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2007.11.059 · Cited by 651
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Tomasi, D. G., & Volkow, N. D. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001414107 · Cited by 645
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van der Kouwe, A. J. W., Benner, T., Salat, D. H., & Fischl, B. R. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2007.12.025 · Cited by 597
Mapping sources of correlation in resting state FMRI, with artifact detection and removal
Jo, H. J., Saad, Z. S., Simmons, W. K., Milbury, L. A., & Cox, R. W. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.04.246 · Cited by 509
Genetic control over the resting brain
Glahn, D. C., Winkler, A. M., Kochunov, P., Almasy, L., Duggirala, R., Carless, M. A., Curran, J. C., Olvera, R. L., Laird, A. R., Smith, S. M., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909969107 · Cited by 450
The Organization of Local and Distant Functional Connectivity in the Human Brain
Sepulcre, J., Liu, H., Talukdar, T., Martincorena, I., Yeo, B. T. T., & Buckner, R. L. (2010) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000808 · Cited by 428
Self-citationGenetic Influences on Cost-Efficient Organization of Human Cortical Functional Networks
Fornito, A., Zalesky, A., Bassett, D. S., David Meunier, A., Ellison-Wright, I., Yücel, M., Wood, S. J., Shaw, K., O'Connor, J., Nertney, D. A., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.4858-10.2011 · Cited by 286
Birn, R. M., Murphy, K., & Bandettini, P. A. (2008) · Human Brain Mapping · doi:10.1002/hbm.20577 · Cited by 283
Brain motion: measurement with phase-contrast MR imaging.
Enzmann, D. R., & Pelc, N. J. (1992) · Radiology · doi:10.1148/radiology.185.3.1438741 · Cited by 275
Test-retest reproducibility of the default-mode network in healthy individuals
Meindl, T., Teipel, S., Elmouden, R., Mueller, S., Koch, W., Dietrich, O., Coates, U., Reiser, M., & Glaser, C. (2010) · Human Brain Mapping · doi:10.1002/hbm.20860 · Cited by 220
Functional magnetic resonance imaging
(2018) · Physics Subject Headings (PhySH) · doi:10.29172/99ff0294e6af41679a7239d01dcd5dad · Cited by 210
Functional magnetic resonance imaging
Khaliq, A. A., Qureshi, I. M., Shah, J. A., & Malik, S. A. (2004) · Choice Reviews Online · doi:10.5860/choice.42-2253 · Cited by 179
Quantifying Head Motion Associated with Motor Tasks Used in fMRI
Seto, E., Gal Sela, D., McIlroy, W. E., Black, S. E., Staines, R. W., Bronskill, M. J., McIntosh, A. R., & Graham, S. J. (2001) · NeuroImage · doi:10.1006/nimg.2001.0829 · Cited by 170
On-line automatic slice positioning for brain MR imaging
van der Kouwe, A. J. W., Benner, T., Fischl, B. R., Schmitt, F., Salat, D. H., Harder, M., Sorensen, A. G., & Dale, A. M. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.03.035 · Cited by 168
Isolating physiologic noise sources with independently determined spatial measures
Beall, E. B., & Lowe, M. J. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.07.004 · Cited by 157
Fornito, A., & Bullmore, E. T. (2010) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e328337d78d · Cited by 146
Development of the Brain’s Functional Network Architecture
Vogel, A. C., Power, J. D., Petersen, S. E., & Schlaggar, B. L. (2010) · Neuropsychology Review · doi:10.1007/s11065-010-9145-7 · Cited by 143
Prospective multiaxial motion correction for fMRI
Ward, H. A., Riederer, S. J., Grimm, R. C., Ehman, R. L., Felmlee, J. P., & Jack, C. R. (2000) · Magnetic Resonance in Medicine · doi:10.1002/(sici)1522-2594(200003)43:3 · Cited by 132
Human functional connectivity: new tools, unresolved questions
Buckner, R. L. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005987107 · Cited by 80
Self-citationYang, S., Ross, T. J., Zhang, Y., Stein, E. A., & Yang, Y. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.02.050 · Cited by 45
The non-separability of physiologic noise in functional connectivity MRI with spatial ICA at 3 T
Beall, E. B., & Lowe, M. J. (2010) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2010.06.024 · Cited by 39
Slow vasomotor fluctuation in fMRI of anesthetized child brain
Kiviniemi, V., Jauhiainen, J., Tervonen, O., P��kk�, E., Oikarinen, J., Vainionp��, V., Rantala, H., & Biswal, B. (2000) · Magnetic Resonance in Medicine · doi:10.1002/1522-2594(200009)44:3
Glover (2000) · doi:10.1002/1522-2594(200007)44:1
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Metadata
- Authors
- Van Dijk, K. R. A., Sabuncu, M. R., & Buckner, R. L.
- Affiliations
- Massachusetts General Hospital (US)
- Howard Hughes Medical Institute (US)
- Corresponding author
- Buckner, Randy L.
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2012-01
- Volume
- 59
- Issue
- 1
- Pages
- 431-438
- ISSN
- 1053-8119 (ISSN-L)
- PMC
- PMC3683830
- OpenAlex
- W2132175842
- Cited by
- 2,344
- References
- 47
- Citations by year
- 2026: 59 · 2025: 80 · 2024: 85 · 2023: 107 · 2022: 126 · 2021: 141 · 2020: 174 · 2019: 234 · 2018: 184 · 2017: 191 · 2016: 214 · 2015: 238 · 2014: 206 · 2013: 203 · 2012: 92
- FWCI
- 82.44
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- NeuroImage (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIA (AG021910, P41RR14074, K08MH067966)
- Howard Hughes Medical Institute
- Simons Foundation
- NIH (1KL2RR025757)
- Harvard University
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Keywords
- head movement, functional connectivity, resting-state fMRI, default mode network, frontoparietal network, functional coupling, micromotion, head rotation, interindividual variability, confounding
- MeSH terms
- Adolescent, Adult, Brain, Brain Mapping, Female, Head, Humans, Image Interpretation, Computer-Assisted, Magnetic Resonance Imaging, Male, Motion, Movement, Neural Pathways, Young Adult
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