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Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank

Open access
Alfaro-Almagro, Fidel, Jenkinson, Mark, Bangerter, Neal K., Andersson, Jesper L.R., Griffanti, Ludovica, Douaud, Gwenaëlle, Sotiropoulos, Stamatios N., Jbabdi, Saad, Hernandez-Fernandez, Moises, Vallee, Emmanuel, Vidaurre, Diego, Webster, Matthew, McCarthy, Paul, Rorden, Christopher, Daducci, Alessandro, Alexander, Daniel C., Zhang, Hui, Dragonu, Iulius, Matthews, Paul M., Miller, Karla L., Smith, Stephen M.·2018·NeuroImage

Abstract

UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound and low-dose bone/fat x-ray. The brain imaging component covers 6 modalities (T1, T2 FLAIR, susceptibility weighted MRI, Resting fMRI, Task fMRI and Diffusion MRI). Raw and processed data from the first 10,000 imaged subjects has recently been released for general research access. To help convert this data into useful summary information we have developed an automated processing and QC (Quality Control) pipeline that is available for use by other researchers. In this paper we describe the pipeline in detail, following a brief overview of UK Biobank brain imaging and the acquisition protocol. We also describe several quantitative investigations carried out as part of the development of both the imaging protocol and the processing pipeline.

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Metadata

Authors
Alfaro-Almagro, F., Jenkinson, M., Bangerter, N. K., Andersson, J. L. R., Griffanti, L., Douaud, G., Sotiropoulos, S. N., Jbabdi, S., Hernandez-Fernandez, M., Vallee, E., Vidaurre, D., Webster, M., McCarthy, P., Rorden, C., Daducci, A., Alexander, D. C., Zhang, H., Dragonu, I., Matthews, P. M., Miller, K. L., & Smith, S. M.
Venue
NeuroImage
Publisher
Elsevier BV
Published
2018-02
Volume
166
Pages
400-424
ISSN
1053-8119 (ISSN-L)
OpenAlex
W2607804943
Cited by
1,557
References
13
FWCI
43.17
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank. https://app.cochat.ai/papers/10.1016/j.neuroimage.2017.10.034
The paper
Alfaro-Almagro, F., Jenkinson, M., Bangerter, N. K., Andersson, J. L. R., Griffanti, L., Douaud, G., Sotiropoulos, S. N., Jbabdi, S., Hernandez-Fernandez, M., Vallee, E., Vidaurre, D., Webster, M., McCarthy, P., Rorden, C., Daducci, A., Alexander, D. C., Zhang, H., Dragonu, I., Matthews, P. M., . . . Smith, S. M. (2018). Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank. NeuroImage. https://doi.org/10.1016/j.neuroimage.2017.10.034

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