The Endocannabinoid Anandamide Protects Neurons during CNS Inflammation by Induction of MKP-1 in Microglial Cells

Eljaschewitsch, Eva, Witting, Anke, Mawrin, Christian, Lee, Thomas, Schmidt, Peter M., Wolf, Susanne, Hoertnagl, Heide, Raine, Cedric S. +3 more·2006·Neuron

DOI 10.1016/j.neuron.2005.11.027

Cited by (446)

Items 101–200 of 446

A Cytochrome P450-Derived Epoxygenated Metabolite of Anandamide Is a Potent Cannabinoid Receptor 2-Selective Agonist
Natasha Tasheva Snider, James A. Nast, Laura A. Tesmer, Paul F. Hollenberg · 2009 · Molecular Pharmacology
Abnormalities in the cerebrospinal fluid levels of endocannabinoids in multiple sclerosis
Massimiliano Di Filippo, Luigi Alberto Pini, Gian Piero Pelliccioli, Paolo Calabresi, Paola Sarchielli · 2008 · Journal of Neurology Neurosurgery & Psychiatry
Transforming growth factor‐β stimulates β amyloid uptake by microglia through Smad3‐dependent mechanisms
Juan Enrique Tichauer, Rommy von Bernhardi M. · 2012 · Journal of Neuroscience Research
Blockade of monoacylglycerol lipase inhibits oligodendrocyte excitotoxicity and prevents demyelination<i>in vivo</i>: MAGL Blockade Protects Oligodendrocytes and Myelin
Bernal-Chico, Ana, Canedo, Manuel, Manterola, Andrea, Victoria Sánchez-Gómez, María, Pérez-Samartín, Alberto, Rodríguez-Puertas, Rafael, Matute, Carlos, Mato, Susana · 2015 · Glia
The Endocannabinoid System in Peripheral Lymphocytes as a Mirror of Neuroinflammatory Diseases
Diego Centonze, Luca Battistini, Mauro Maccarrone · 2008 · Current Pharmaceutical Design
2‐Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal‐cannabidiol‐sensitive receptors on microglial cells
Susanne Kreutz, Marco Koch, Charlotte Böttger, Chalid Ghadban, Horst‐Werner Korf, Faramarz Dehghani · 2008 · Glia
Epigenetic mechanisms and endocannabinoid signalling
Claudio D’Addario, Andrea Di Francesco, Mariangela Pucci, Alessandro Finazzi‐Agrò, Mauro Maccarrone · 2013 · FEBS Journal
Glial expression of cannabinoid CB2 receptors and fatty acid amide hydrolase are beta amyloid–linked events in Down’s syndrome
Estefanía Núñez, Cristina Benito, Rosa Maria Tolón, Cecilia J. Hillard, W. Sue T. Griffin, Julián Romero · 2008 · Neuroscience
Proteolytic Activation of Monocyte Chemoattractant Protein-1 by Plasmin Underlies Excitotoxic Neurodegeneration in Mice
John J. Sheehan, Chun Zhou, Iordanis Gravanis, Andrew D. Rogove, Yanping Wu, Daniel F. Bogenhagen, Stella E. Tsirka · 2007 · Journal of Neuroscience
CB1 and CB2 Cannabinoid Receptor Antagonists Prevent Minocycline-Induced Neuroprotection Following Traumatic Brain Injury in Mice
Ana Belén López-Rodríguez, Eleni Siopi, David P. Finn, Catherine Marchand‐Leroux, Luis Miguel García‐Segura, Mehrnaz Jafarian-Tehrani, María‐Paz Viveros · 2013 · Cerebral Cortex
Brain CB2 Receptors: Implications for Neuropsychiatric Disorders
Michelle Roche, David P. Finn · 2010 · Pharmaceuticals
From endocannabinoid profiling to ‘endocannabinoid therapeutics’
Alessia Ligresti, Stefania Petrosino, Vincenzo Di Marzo · 2009 · Current Opinion in Chemical Biology
Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro
Harvey, Benjamin S., Ohlsson, Katharina S., Mååg, Jesper L.V., Musgrave, Ian F., Smid, Scott D. · 2012 · NeuroToxicology
Cannabinoid CB1 receptors regulate neuronal TNF-α effects in experimental autoimmune encephalomyelitis
Silvia Rossi, Roberto Furlan, Valentina De Chiara, Luca Muzio, Alessandra Musella, Caterina Motta, Valeria Studer, Francesca Cavasinni, Giorgio Bernardi, Gianvito Martino et al. · 2011 · Brain Behavior and Immunity
Cannabinoid CB<sub>2</sub>receptor attenuates morphine‐induced inflammatory responses in activated microglial cells
Merighi, Stefania, Gessi, Stefania, Varani, Katia, Fazzi, Debora, Mirandola, Prisco, Borea, Pier Andrea · 2012 · British Journal of Pharmacology
Induction of apoptosis by cannabinoids in prostate and colon cancer cells is phosphatase dependent.
Sandeep Sreevalsan, Sonia Joseph, Indira Jutooru, Gayathri Chadalapaka, Stephen H Safe · 2011 · PubMed
The endocannabinoid system in the inflammatory and neurodegenerative processes of multiple sclerosis and of amyotrophic lateral sclerosis.
S. Rossi, G. Bernardi, D. Centonze · 2010 · Experimental Neurology
Alteration of imprinted Dlk1-Dio3 miRNA cluster expression in the entorhinal cortex induced by maternal immune activation and adolescent cannabinoid exposure
Sharon L. Hollins, Katerina Zavitsanou, Frederick Rohan Walker, Murray J. Cairns · 2014 · Translational Psychiatry
Endocannabinoids alleviate proinflammatory conditions by modulating innate immune response in muller glia during inflammation
Gopinath Krishnan, Nivedita Chatterjee · 2012 · Glia
The cannabinoid CB 2 receptor agonist AM 1241 enhances neurogenesis in GFAP / G p120 transgenic mice displaying deficits in neurogenesis
Hava Karsenty Avraham, Shuxian Jiang, Yigong Fu, Edward M. Rockenstein, Alexandros Makriyannis, Alexander M. Zvonok, Eliezer Masliah, Shalom Avraham · 2013 · British Journal of Pharmacology
Prevention of Paclitaxel-Induced Neuropathy Through Activation of the Central Cannabinoid Type 2 Receptor System
Mohamed Naguib, Jijun J. Xu, Philippe Diaz, David L. Brown, David E. Cogdell, Bihua Bie, Jianhua Hu, Suzanne L. Craig, Walter N. Hittelman · 2012 · Anesthesia & Analgesia
Brain Innate Immunity in the Regulation of Neuroinflammation: Therapeutic Strategies by Modulating CD200-CD200R Interaction Involve the Cannabinoid System
Míriam Hernangómez, Francisco Javier Carrillo-Salinas, Míriam Mecha, Fernando Correa, Leyre Mestre, Frida Loría, Ana Feliú, Fabián Docagne, Carmen Guaza · 2014 · Current Pharmaceutical Design
Cannabinoids ameliorate disease progression in a model of multiple sclerosis in mice, acting preferentially through CB1 receptor-mediated anti-inflammatory effects
Eva de Lago, Miguel Moreno‐Martet, Ana Cabranes, José Antonio Ramos, Javier Fernández‐Ruíz · 2012 · Neuropharmacology
The Cannabinoid Agonist Win55212 Reduces Brain Damage in an In Vivo Model of Hypoxic-Ischemic Encephalopathy in Newborn Rats
David Fernández‐López, María Ruth Pazos, Rosa Maria Tolón, María Ángeles Moro, Julián Romero, Ignacio Lizasoaín, José Antonio Martínez-Orgado · 2007 · Pediatric Research
CB2 cannabinoid receptors as an emerging target for demyelinating diseases: from neuroimmune interactions to cell replacement strategies
Ángel Arévalo‐Martín, Daniel García‐Ovejero, Oscar Gómez, Ana Rubio‐Araiz, Beatriz Navarro‐Galve, Carmen Guaza, Eduardo Molina‐Holgado, Francisco Molina‐Holgado · 2007 · British Journal of Pharmacology
The endocannabinoid anandamide downregulates IL-23 and IL-12 subunits in a viral model of multiple sclerosis: Evidence for a cross-talk between IL-12p70/IL-23 axis and IL-10 in microglial cells
Fernando Correa, Míriam Hernangómez, Leyre Mestre, Frida Loría, Fabián Docagne, Carmen Guaza · 2011 · Brain Behavior and Immunity
Interaction between cytokines, cannabinoids and the nervous system
Lucie Jean-Gilles, Bruno Gran, Cris S. Constantinescu · 2010 · Immunobiology
Dual-Specificity Phosphatase Regulation in Neurons and Glial Cells
Raquel Pérez‐Sen, Ma José Queipo, Juan Carlos Gil‐Redondo, Felipe Ortega, Rosa Gómez‐Villafuertes, M. Teresa Miras‐Portugal, Esmerilda G. Delicado · 2019 · International Journal of Molecular Sciences
Cannabinoids: Current and Future Options to Treat Chronic and Chemotherapy-Induced Neuropathic Pain
Henry L. Blanton, Jennifer Brelsfoard, Nathan Deturk, Kevin Pruitt, Madhusudhanan Narasimhan, Daniel J. Morgan, Josée Guindon · 2019 · Drugs
Cannabinoid control of neuroinflammation related to multiple sclerosis
David Baker, S J Jackson, Gareth Pryce · 2007 · British Journal of Pharmacology
Cannabinoid Signaling and Neuroinflammatory Diseases: A Melting pot for the Regulation of Brain Immune Responses
Valerio Chiurchiù, Alessandro Leuti, Mauro Maccarrone · 2015 · Journal of Neuroimmune Pharmacology
Inflammation modulates expression of laminin in the central nervous system following ischemic injury
Kyungmin Ji, Stella E. Tsirka · 2012 · Journal of Neuroinflammation
Transient increase of interleukin-1β after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling
Bo Feng, Yangshun Tang, Bin Chen, Cenglin Xu, Yi Wang, Yunjian Dai, Dengchang Wu, Junmin Zhu, Shuang Wang, Yudong Zhou et al. · 2016 · Scientific Reports
Neuroinflammation, Early-Life Adversity, and Brain Development
Susan L. Andersen · 2022 · Harvard Review of Psychiatry
Inhibition of histone deacetylase 1 or 2 reduces induced cytokine expression in microglia through a protein synthesis independent mechanism
Benjamin S. Durham, Ronald Grigg, Ian C. Wood · 2017 · Journal of Neurochemistry
Effects of cannabinoids and their receptors on viral infections
Alireza Tahamtan, Masoumeh Tavakoli‐Yaraki, Tomasz P. Rygiel, Talat Mokhtari‐Azad, Vahid Salimi · 2015 · Journal of Medical Virology
Oxidative Mechanisms of Brain Dysfunction During Sepsis
Felipe Dal‐Pizzol, Cristiane Ritter, Omar J. Cassol-Jr, Gislaine Tezza Rezin, Fabricia Cardoso Petronilho, Alexandra Ioppi Zugno, João Quevedo, Emilio Luiz STRECK · 2009 · Neurochemical Research
The synaptic impact of the host immune response in a parkinsonian allograft rat model: Influence on graft-derived aberrant behaviors
Katherine E. Soderstrom, Gloria E. Meredith, T.B. Freeman, Susan O. McGuire, Timothy J. Collier, Caryl E. Sortwell, Qun Wu, Kathy Steece‐Collier · 2008 · Neurobiology of Disease
Neuroprotective effects of the cannabinoid agonist HU210 on retinal degeneration
Pedro Lax, Gema Esquiva, Cesare Altavilla, Nicolás Cuenca · 2014 · Experimental Eye Research
Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB1receptors
Leyre Mestre, Paula M. Iñigo, Míriam Mecha, Fernando Correa, Míriam Hernangómez, Frida Loría, Fabián Docagne, José Ignacio Borrell, Carmen Guaza · 2011 · Journal of Neuroinflammation
Functional Aspects of Redox Control During Neuroinflammation
Sergio Rosales‐Corral, Russel Joseph Reiter, Dun‐Xian Tan, Genaro G. Ortiz, Gabriela del Carmen López-Armas · 2009 · Antioxidants and Redox Signaling
Potentiation of cannabinoid signaling in microglia by adenosine A2A receptor antagonists
Rafael Franco, Irene Reyes‐Resina, David Aguinaga, Alejandro Lillo, Jasmina Jiménez, Iu Raïch, Dasiel O. Borroto‐Escuela, Carlos Ferreiro‐Vera, Enric I. Canela, Verónica Sánchez de Medina et al. · 2019 · Glia
CB1 Knockout Mice Unveil Sustained CB2-Mediated Antiallodynic Effects of the Mixed CB1/CB2 Agonist CP55,940 in a Mouse Model of Paclitaxel-Induced Neuropathic Pain
Liting Deng, Ben Cornett, Ken Mackie, Andrea G. Hohmann · 2015 · Molecular Pharmacology
The Neurotherapeutic Arsenal in Cannabis sativa: Insights into Anti-Neuroinflammatory and Neuroprotective Activity and Potential Entourage Effects
Ahmad K. Al-Khazaleh, Xian Zhou, Deep Jyoti Bhuyan, Gerald W Münch, Elaf Adel Al-Dalabeeh, Kayla M. Jaye, Dennis Chang · 2024 · Molecules
Cannabinoids in health and disease: pharmacological potential in metabolic syndrome and neuroinflammation
Andrea Mastinu, Marika Premoli, Giulia Ferrari‐Toninelli, Simone Tambaro, Giuseppina Maccarinelli, Maurizio Memo, Sara Anna Bonini · 2018 · Hormone Molecular Biology and Clinical Investigation
Cannabinoids as Therapeutic Agents for Ablating Neuroinflammatory Disease
G. A. Cabral, LaToya Griffin-Thomas · 2008 · Endocrine Metabolic & Immune Disorders - Drug Targets
Toxoplasmosis and neuropsychiatric diseases: can serological studies establish a clear relationship?
Silvia Fabiani, Barbara Pinto, Fabrizio Bruschi · 2012 · Neurological Sciences
Dietary Grape Seed Polyphenols Repress Neuron and Glia Activation in Trigeminal Ganglion and Trigeminal Nucleus Caudalis
Ryan J. Cady, Jeffery J Hirst, Paul L. Durham · 2010 · Molecular Pain
Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-β1a and Circulating Proinflammatory Cytokines in Relapsing–Remitting Multiple Sclerosis
Nicola Salvatore Orefice, Mireille Alhouayek, Antonio Carotenuto, Silvana Montella, Francesco Barbato, Albert Comelli, Antonio Calignano, Giulio G. Muccioli, Giuseppe Orefice · 2016 · Neurotherapeutics
Inhibition of microglial fatty acid amide hydrolase modulates LPS stimulated release of inflammatory mediators
Chui‐Se Tham, John Whitaker, Lin Luo, Michael Webb · 2007 · FEBS Letters
Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling
Strahil I. Pastuhov, Kota Fujiki, P. Nix, Shuka Kanao, M. Bastiani, Kunihiro Matsumoto, Naoki Hisamoto · 2012 · Nature Communications
Minocycline Attenuates Neonatal Germinal-Matrix-Hemorrhage-Induced Neuroinflammation and Brain Edema by Activating Cannabinoid Receptor 2
Jun Tang, Qianwei Chen, Jing Guo, Liming M Yang, Yihao Tao, Lin Li, Hongping Miao, Hua Feng, Zhi Chen, Gang Zhu · 2015 · Molecular Neurobiology
Short- and long-term plasticity of the endocannabinoid system in neuropsychiatric and neurological disorders
Tiziana Bisogno, Vincenzo Di Marzo · 2007 · Pharmacological Research
Müller cells express the cannabinoid CB2 receptor in the vervet monkey retina
Joseph Bouskila, Pasha Javadi, Christian Casanova, Maurice Ptito, Jean‐François Bouchard · 2013 · The Journal of Comparative Neurology
Immune system: A possible nexus between cannabinoids and psychosis
Paula Suárez‐Pinilla, José López-Gil, Benedicto Crespo‐Facorro · 2014 · Brain Behavior and Immunity
Involvement of ERK1/2, cPLA2 and NF-κB in microglia suppression by cannabinoid receptor agonists and antagonists
Rachel Ribeiro, Jie Wen, Shihe Li, Yumin Zhang · 2012 · Prostaglandins & Other Lipid Mediators
Inhibition of Endocannabinoid Degradation Improves Outcomes from Mild Traumatic Brain Injury: A Mechanistic Role for Synaptic Hyperexcitability
Jacques P. Mayeux, Paige S. Katz, Scott Edwards, Jason W. Middleton, Patricia E. Molina · 2016 · Journal of Neurotrauma
Activation of Cannabinoid Type Two Receptors (CB2) Diminish Inflammatory Responses in Macrophages and Brain Endothelium
Yuri Persidsky, Shongshan Fan, Holly Dykstra, Nancy Lee Reichenbach, Slava Rom, Servio H. Ramirez · 2015 · Journal of Neuroimmune Pharmacology
Importance of GPCR-Mediated Microglial Activation in Alzheimer’s Disease
Md. Ezazul Haque, In‐Su Kim, Md. Jakaria, Mahbuba Akther, Dong‐Kug Choi · 2018 · Frontiers in Cellular Neuroscience
Retracted:Cannabinoid CB2receptors modulate ERK‐1/2 kinase signalling and NO release in microglial cells stimulated with bacterial lipopolysaccharide
Stefania Merighi, Stefania Gessi, Katia Varani, Carolina Simioni, Debora Fazzi, Prisco Mirandola, Pier Andrea Borea · 2011 · British Journal of Pharmacology · Retracted
Spinal Cannabinoid Receptor Type 2 Agonist Reduces Mechanical Allodynia and Induces Mitogen-Activated Protein Kinase Phosphatases in a Rat Model of Neuropathic Pain
Russell P. Landry, Elena Martinez, Joyce A. DeLeo, Edgar Alfonso Romero-Sandoval · 2012 · Journal of Pain
Neuroprotection in Experimental Autoimmune Encephalomyelitis and Progressive Multiple Sclerosis by Cannabis-Based Cannabinoids
Gareth Pryce, Dieter Riddall, David L. Selwood, Gavin Giovannoni, David Baker · 2014 · Journal of Neuroimmune Pharmacology
The central cannabinoid receptor type-2 (CB2) and chronic pain
Yu-chao Shang, Yuying Tang · 2016 · International Journal of Neuroscience
Immune control by endocannabinoids — New mechanisms of neuroprotection?
Oliver Ullrich, Katrin Merker, Johanna Timm, Svantje Tauber · 2006 · Journal of Neuroimmunology
N -Arachidonoyl Dopamine: A Novel Endocannabinoid and Endovanilloid with Widespread Physiological and Pharmacological Activities
Urszula Hohmann, Faramarz Dehghani · 2017 · Cannabis and Cannabinoid Research
Cannabinoid Receptor and N‐acyl Phosphatidylethanolamine Phospholipase D—Evidence for Altered Expression in Multiple Sclerosis
Hua Zhang, David A. Hilton, Clemens Oliver Hanemann, John Zajicek · 2011 · Brain Pathology
Discovery and Optimization of a Novel Series ofN-Arylamide Oxadiazoles as Potent, Highly Selective and Orally Bioavailable Cannabinoid Receptor 2 (CB2) Agonists
Yuan Cheng, Brian K. Albrecht, James Brown, John L. Buchanan, William H. Buckner, Erin F. DiMauro, Renee Emkey, Robert T. Fremeau, Jean-Christophe Harmange, Beth J. Hoffman et al. · 2008 · Journal of Medicinal Chemistry
Cannabidiol and Cannabinoid Compounds as Potential Strategies for Treating Parkinson’s Disease and l-DOPA-Induced Dyskinesia
Nilson Carlos Ferreira‐Junior, Maurício dos Santos Pereira, Francisco Silveira Guimarães, Elaine Del Bel · 2019 · Neurotoxicity Research
Cannabinoids and neuronal damage: Differential effects of THC, AEA and 2-AG on activated microglial cells and degenerating neurons in excitotoxically lesioned rat organotypic hippocampal slice cultures
Susanne Kreutz, Marco Koch, Chalid Ghadban, Horst‐Werner Korf, Faramarz Dehghani · 2006 · Experimental Neurology
Endocannabinoid signaling in brain diseases: Emerging relevance of glial cells
Ana Bernal‐Chico, Vanja Tepavčević, Andrea Manterola, Carmen L. Utrilla, Carlos Matute, Susana Mato · 2022 · Glia
Cannabinoid receptor expression in HIV encephalitis and HIV‐associated neuropathologic comorbidities
Melissa A. Cosenza-Nashat, A. Bauman, Meng Liang Zhao, Susan Morgello, H.‐S. Suh, Sunhee C. Lee · 2011 · Neuropathology and Applied Neurobiology
Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells
Shu-Shong Hsu, Chun‐Jen Huang, He‐Hsiung Cheng, Chiang‐Ting Chou, Hsiao-Ying Lee, Jue‐Long Wang, I-Shu Chen, Shiuh‐Inn Liu, Yih‐Chau Lu, Hong‐Tai Chang et al. · 2006 · Toxicology
Cannabinoid CB2 Receptors in Neurodegenerative Proteinopathies: New Insights and Therapeutic Potential
Barbara Vuić, Tina Milos, Lucija Tudor, Marcela Konjevod, Matea Nikolac Perković, Maja Jazvinšćak Jembrek, Gordana Nedić Erjavec, Dubravka Švob Štrac · 2022 · Biomedicines
The role of glia in late-life depression
Matthew Paradise, Sharon Linda Naismith, Louisa Margaret Norrie, Manuel B. Graeber, Ian Bernard Hickie · 2012 · International Psychogeriatrics
ARCHIVOS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGÍA
Alfonso Iglesias, M. Casta · 2016
[125I]SD-7015 reveals fine modalities of CB1 cannabinoid receptor density in the prefrontal cortex during progression of Alzheimer’s disease
Szabolcs Farkas, Katalin Nagy, Miklós Palkovits, Gábor Géza Kovács, Zhisheng Jia, Sean R. Donohue, Victor W. Pike, Christer Halldin, Domokos Máthé, Tibor Harkany et al. · 2011 · Neurochemistry International
Inhibition of mitogen-activated protein kinase phosphatase-1 (MKP-1) increases experimental stroke injury
Lin Liu, Sarah J. Doran, Yan Xu, Bharti Manwani, Rodney M. Ritzel, Sharon E. Benashski, Louise D. McCullough, Jun Li · 2014 · Experimental Neurology
Deregulation of the endocannabinoid system and therapeutic potential of ABHD6 blockade in the cuprizone model of demyelination
Andrea Manterola, Ana Bernal‐Chico, Raffaela Cipriani, Manuel Canedo-Antelo, A. Moreno‐García, Mar Martín‐Fontecha, Fernando Pérez‐Cerdá, María Victoria Sánchez‐Gómez, Silvia Ortega‐Gutiérrez, Jonathan Mark Brown et al. · 2018 · Biochemical Pharmacology
MAP kinase phosphatase-1, a gatekeeper of the acute innate immune response
Sean G. Kirk, Lobelia Samavati, Liu Y · 2019 · Life Sciences
Cannabinoids in Chronic Pain: Therapeutic Potential Through Microglia Modulation
van den Hoogen, Nynke J., Harding, Erika K., Davidson, Chloé E. D., Trang, Tuan · 2022 · Frontiers in Neural Circuits
A cannabinoid receptor 2 agonist reduces blood–brain barrier damage via induction of MKP-1 after intracerebral hemorrhage in rats
Lin Li, Debo Yun, Yuan Zhang, Yihao Tao, Qiang Tan, Fei Qiao, Bo Luo, Yi Liu, Runjin Fan, Jishu Xian et al. · 2018 · Brain Research
Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology
R. Rodrigues, D. Lourenço, S. Paulo, J. Mateus, M. A. Ferreira, Francisco M. Mouro, J. B. Moreira, F. Ribeiro, A. Sebastião, S. Xapelli · 2019 · Molecules
The endocannabinoidome in neuropsychiatry: Opportunities and potential risks
Gerwyn Morris, Ken R. Walder, Stefan M. Kloiber, G. Paul Amminger, Michael Berk, Chiara C. Bortolasci, Michael H. J. Maes, Basant K. Puri, Andre Ferrer Carvalho · 2021 · Pharmacological Research
The cannabinoid WIN 55,212‐2‐mediated protection of dentate gyrus granule cells is driven by CB1receptors and modulated by TRPA1 and Cav2.2 channels
Marco Koch, Susanne Kreutz, Charlotte Böttger, Urszula Grabiec, Chalid Ghadban, Horst‐Werner Korf, Faramarz Dehghani · 2010 · Hippocampus
Immunomodulatory Role of CB2 Receptors in Emotional and Cognitive Disorders
Álvaro Morcuende, María S. García‐Gutiérrez, Simone Tambaro, Elena Otón Nieto, Jorge Manzanares, Teresa Femenía · 2022 · Frontiers in Psychiatry
Potential Therapeutical Contributions of the Endocannabinoid System towards Aging and Alzheimer’s Disease
Amandine EB, Yannick Marchalant · 2015 · Aging and Disease
Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist
Suneeta Tumati, Tally M. Largent‐Milnes, Attila I. Keresztes, Jiyang Ren, William R. Roeske, Todd W. Vanderah, Eva V. Varga · 2012 · Journal of Neuroimmunology
Evidence that MDMA (‘ecstasy’) increases cannabinoid CB2 receptor expression in microglial cells: role in the neuroinflammatory response in rat brain
Elisa Torres, María Dolores Gutiérrez‐López, Érika Borcel, Inés Peraile, Andrea Mayado, Esther O’Shea, María Isabel Colado · 2010 · Journal of Neurochemistry
Genetic deletion of Fatty Acid Amide Hydrolase results in improved long-term outcome in chronic autoimmune encephalitis
Meghan Webb, Lin Luo, Ying Jing, Chui‐Se Tham · 2008 · Neuroscience Letters
Neuron‐microglia crosstalk up‐regulates neuronal FGF‐2 expression which mediates neuroprotection against excitotoxicity via JNK1/2
Catarina Figueiredo, Teresa Faria Pais, João R. Gomes, Sukalyan Chatterjee · 2008 · Journal of Neurochemistry
Toll-like receptor signalling as a cannabinoid target in Multiple Sclerosis
John-Mark Fitzpatrick, Eric J. Downer · 2016 · Neuropharmacology
Regulation of cannabinoid receptor gene expression and endocannabinoid levels in lymphocyte subsets by interferon-β: a longitudinal study in multiple sclerosis patients
Antonio Sánchez, L Román-Vega, Elvira Ramil, Andrea Giuffrida, A. Garcı́a-Merino · 2014 · Clinical & Experimental Immunology
Endocannabinoids regulate the activity of astrocytic hemichannels and the microglial response against an injury: In vivo studies
Carmen Vázquez, Rosa Maria Tolón, María Ruth Pazos, Marta Moreno, Erin C. Koester, Benjamin F. Cravatt, Cecilia J. Hillard, Julián Romero · 2015 · Neurobiology of Disease
Estradiol Decreases Cortical Reactive Astrogliosis after Brain Injury by a Mechanism Involving Cannabinoid Receptors
Ana Belén López-Rodríguez, B. Mateos Vicente, Silvana‐Yanina Romero‐Zerbo, Noé Rodríguez‐Rodríguez, María José Bellini, Fernando Rodrı́guez de Fonseca, Francisco Javier Bermúdez‐Silva, Íñigo Azcoitia, Luis Miguel García‐Segura, María‐Paz Viveros · 2011 · Cerebral Cortex
Role of Endocannabinoid Activation of Peripheral CB1 Receptors in the Regulation of Autoimmune Disease
Jessica Margaret Sido, Prakash S. Nagarkatti, Mitzi Nagarkatti · 2014 · International Reviews of Immunology
Gut microbiota, cannabinoid system and neuroimmune interactions: New perspectives in multiple sclerosis
Leyre Mestre, Francisco Javier Carrillo-Salinas, Míriam Mecha, Ana Feliú, Carmen Guaza · 2018 · Biochemical Pharmacology
Non‐psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors‐, endocannabinoids‐, and NF‐κB ‐mediated signaling
Vittoria Borgonetti, Cristina Benatti, Paolo Governa, Giovanni Isoldi, Federica Pellati, Silvia Alboni, Fabio Tascedda, Monica Montopoli, Nicoletta Galeotti, Fabrizio Manetti et al. · 2022 · Phytotherapy Research
Microglial Cannabinoid CB2 Receptors in Pain Modulation
Kangtai Xu, Yifei Wu, Zhuangzhuang Tian, Yuanfan Xu, Chaoran Wu, Zilong Wang · 2023 · International Journal of Molecular Sciences
Perspectives on Cannabis-Based Therapy of Multiple Sclerosis: A Mini-Review
Míriam Mecha, Francisco Javier Carrillo-Salinas, Ana Feliú, Leyre Mestre, Carmen Guaza · 2020 · Frontiers in Cellular Neuroscience
Gene Expression Analysis of Astrocyte and Microglia Endocannabinoid Signaling during Autoimmune Demyelination
A. Moreno‐García, Ana Bernal‐Chico, Teresa Colomer, Alfredo Rodríguez-Antigüedad, Carlos Matute, Susana Mato · 2020 · Biomolecules