The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.
Structural and Mechanistic Insights into Nerve Growth Factor Interactions with the TrkA and p75 Receptors
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[20] Processing of X-ray diffraction data collected in oscillation mode
Otwinowski, Z., & Minor, W. (1997) · Methods in Enzymology · doi:10.1016/s0076-6879(97)76066-x · Cited by 33,475
Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination
Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., et al. (1998) · Acta Crystallographica Section D Biological Crystallography · doi:10.1107/s0907444998003254 · Cited by 15,715
Trk Receptors: Roles in Neuronal Signal Transduction
Huang, E. J., & Reichardt, L. F. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161629 · Cited by 2,537 · cited 9×
“All neurotrophins (NT-3, NT-4/5, BDNF) bind to p75, while each NT is specific for a different Trk receptor subtype (A-, B-, and C) (Huang and Reichardt, 2003; Kalb, 2005).”
BackgroundInfluentialNeurotrophins and their receptors: A convergence point for many signalling pathways
Chao, M. V. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1078 · Cited by 2,298
The trk proto-oncogene encodes a receptor for nerve growth factor
Klein, R., Jing, S., Nanduri, V., O'Rourke, E., & Barbacid, M. (1991) · Cell · doi:10.1016/0092-8674(91)90419-y · Cited by 1,401
The trk Proto-Oncogene Product: a Signal Transducing Receptor for Nerve Growth Factor
Kaplan, D. R., Hempstead, B. L., Martin-Zanca, D., Chao, M. V., & Parada, L. F. (1991) · Science · doi:10.1126/science.1850549 · Cited by 1,379
Hempstead, B. L., Martin-Zanca, D., Kaplan, D. R., Parada, L. F., & Chao, M. V. (1991) · Nature · doi:10.1038/350678a0 · Cited by 1,229
The leucine-rich repeat: a versatile binding motif
Kobe, B., & Deisenhofer, J. (1994) · Trends in Biochemical Sciences · doi:10.1016/0968-0004(94)90090-6 · Cited by 1,202
Expression and structure of the human NGF receptor
Johnson, D., Lanahan, A., Buck, C. R., Sehgal, A., Morgan, C., Mercer, E., Bothwell, M., & Chao, M. (1986) · Cell · doi:10.1016/0092-8674(86)90619-7 · Cited by 963
Lee, K.-F., Li, E., Huber, L. J., Landis, S. C., Sharpe, A. H., Chao, M. V., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90286-l · Cited by 956
Cited by
Cell Signaling by Receptor Tyrosine Kinases
Lemmon, M. A., & Schlessinger, J. (2010) · Cell · doi:10.1016/j.cell.2010.06.011 · Cited by 7,929
Mechanisms of receptor tyrosine kinase activation in cancer
Du, Z., & Lovly, C. M. (2018) · Molecular Cancer · doi:10.1186/s12943-018-0782-4 · Cited by 1,066
Design of protein-binding proteins from the target structure alone
Cao, L., Coventry, B., Goreshnik, I., Huang, B., Sheffler, W., Park, J. S., Jude, K. M., Marković, I., Kadam, R. U., Verschueren, K. H. G., et al. (2022) · Nature · doi:10.1038/s41586-022-04654-9 · Cited by 577
Self-citationPsychedelics promote plasticity by directly binding to BDNF receptor TrkB
Moliner, R., Girych, M., Brunello, C. A., Kovaleva, V., Biojone, C., Enkavi, G., Antenucci, L., Kot, E. F., Goncharuk, S. A., Kaurinkoski, K., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01316-5 · Cited by 478
The leucine-rich repeat structure
Bella, J., Hindle, K. L., McEwan, P. A., & Lovell, S. C. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8019-0 · Cited by 466
Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents
Massa, S. M., Yang, T., Xie, Y., Shi, J., Bilgen, M., Joyce, J. N., Nehama, D., Rajadas, J., & Longo, F. M. (2010) · Journal of Clinical Investigation · doi:10.1172/jci41356 · Cited by 406
Neurobiology of local and intercellular BDNF signaling
Sasi, M., Vignoli, B., Canossa, M., & Blum, R. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1964-4 · Cited by 324
Structural basis of receptor sharing by interleukin 17 cytokines
Ely, L. K., Fischer, S., & Garcia, K. C. (2009) · Nature Immunology · doi:10.1038/ni.1813 · Cited by 195
Self-citationVolosin, M., Trotter, C., Cragnolini, A., Kenchappa, R. S., Light, M., Hempstead, B. L., Carter, B. D., & Friedman, W. J. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.2841-08.2008 · Cited by 149
The Biological Functions and Signaling Mechanisms of the p75 Neurotrophin Receptor
Kraemer, B. R., Yoon, S. O., & Carter, B. D. (2014) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-642-45106-5_6 · Cited by 125
Cazorla, M., Jouvenceau, A., Rose, C., Guilloux, J.-P., Pilon, C., Dranovsky, A., & Prémont, J. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009777 · Cited by 99
Liu, X., Chan, C.-B., Qi, Q., Xiao, G., Luo, H. R., He, X., & Ye, K. (2012) · Journal of Medicinal Chemistry · doi:10.1021/jm301099x · Cited by 60
Self-citationNeurotrophin receptor agonists and antagonists as therapeutic agents: An evolving paradigm
Josephy-Hernandez, S., Jmaeff, S., Pirvulescu, I., Aboulkassim, T., & Saragovi, H. U. (2017) · Neurobiology of Disease · doi:10.1016/j.nbd.2016.08.004 · Cited by 54
Wong, A. W., Giuffrida, L., Wood, R., Peckham, H., Gonsalvez, D., Murray, S. S., Hughes, R. A., & Xiao, J. (2014) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2014.10.002 · Cited by 39
Small-Molecule Trk Agonists: Where Do We Go from Here?
Thompson, T. S., Sefiani, A., & Burgess, K. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.4c02365 · Cited by 13
Metadata
- Authors
- Wehrman, T., He, X., Raab, B., Dukipatti, A., Blau, H., & Garcia, K. C.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2007-01
- Volume
- 53
- Issue
- 1
- Pages
- 25-38
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2011207394
- Cited by
- 314
- References
- 70
- FWCI
- 9.67
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
