The DOI matches its Crossref record; 118 of the 118 references it cites were found in a registry or an index.
What Is the Role of Astrocyte Calcium in Neurophysiology?
Open accessAbstract
Astrocytes comprise approximately half of the volume of the adult mammalian brain and are the primary neuronal structural and trophic supportive elements. Astrocytes are organized into distinct nonoverlapping domains and extend elaborate and dense fine processes that interact intimately with synapses and cerebrovasculature. The recognition in the mid 1990s that astrocytes undergo elevations in intracellular calcium concentration following activation of G protein-coupled receptors by synaptically released neurotransmitters demonstrated not only that astrocytes display a form of excitability but also that astrocytes may be active participants in brain information processing. The roles that astrocytic calcium elevations play in neurophysiology and especially in modulation of neuronal activity have been intensely researched in recent years. This review will summarize the current understanding of the function of astrocytic calcium signaling in neurophysiological processes and discuss areas where the role of astrocytes remains controversial and will therefore benefit from further study.
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Cited by
Tripartite synapses: astrocytes process and control synaptic information
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Long-term potentiation depends on release of d-serine from astrocytes
Henneberger, C., Papouin, T., Oliet, S. H. R., & Rusakov, D. A. (2010) · Nature · doi:10.1038/nature08673 · Cited by 1,389
The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease
Barres, B. A. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.013 · Cited by 1,352
Diversity of astrocyte functions and phenotypes in neural circuits
Khakh, B. S., & Sofroniew, M. V. (2015) · Nature Neuroscience · doi:10.1038/nn.4043 · Cited by 1,239
Metadata
- Authors
- Agulhon, C., Petravicz, J., McMullen, A. B., Sweger, E. J., Minton, S. K., Taves, S. R., Casper, K. B., Fiacco, T. A., & McCarthy, K. D.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2008-09
- Volume
- 59
- Issue
- 6
- Pages
- 932-946
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W1973361488
- Cited by
- 566
- References
- 118
- FWCI
- 16.19
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Agulhon, C., Petravicz, J., McMullen, A. B., Sweger, E. J., Minton, S. K., Taves, S. R., Casper, K. B., Fiacco, T. A., & McCarthy, K. D. (2008). What Is the Role of Astrocyte Calcium in Neurophysiology? Neuron. https://doi.org/10.1016/j.neuron.2008.09.004
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