The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Decoding the Epigenetic Language of Neuronal Plasticity
Open accessAbstract
Neurons are submitted to an exceptional variety of stimuli and are able to convert these into high-order functions, such as storing memories, controlling behavior, and governing consciousness. These unique properties are based on the highly flexible nature of neurons, a characteristic that can be regulated by the complex molecular machinery that controls gene expression. Epigenetic control, which largely involves events of chromatin remodeling, appears to be one way in which transcriptional regulation of gene expression can be modified in neurons. This review will focus on how epigenetic control in the mature nervous system may guide dynamic plasticity processes and long-lasting cellular neuronal responses. We outline the molecular pathways underlying chromatin transitions, propose the presence of an “epigenetic indexing code,” and discuss how central findings accumulating at an exponential pace in the field of epigenetics are conceptually changing our perspective of adult brain function.
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Cites
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Self-citationDNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation
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Self-citationGlobal epigenomic reconfiguration during mammalian brain development
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Metadata
- Authors
- Borrelli, E., Nestler, E. J., Allis, C. D., & Sassone-Corsi, P.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2008-12
- Volume
- 60
- Issue
- 6
- Pages
- 961-974
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2022818353
- Cited by
- 525
- References
- 30
- FWCI
- 14.15
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.