Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis

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Items 801–900 of 1,002

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8. Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies
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10. Tethering-induced destabilization and ATP-binding for tandem RRM domains of ALS-causing TDP-43 and hnRNPA1
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11. Potential Therapeutic Role of HDAC Inhibitors in FUS-ALS
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12. Aberrant Stress Granule Dynamics and Aggrephagy in ALS Pathogenesis
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14. A network of RNA and protein interactions in Fronto Temporal Dementia
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15. Delineating the effect of mutations on the conformational dynamics of N-terminal domain of TDP-43
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    Jennifer M. Hafycz, Nirinjini N. Naidoo · 2019 · Frontiers in Aging Neuroscience
18. ALS-causing D169G mutation disrupts the ATP-binding capacity of TDP-43 RRM1 domain
    Mei Dang, Jianxing Song · 2020 · Biochemical and Biophysical Research Communications
19. Bromodomain and Extra-Terminal Proteins in Brain Physiology and Pathology: BET-ing on Epigenetic Regulation
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    Ke Ruan, Ge Bai, Yanshan Fang, Dan Li, Tingting Li, Xingguo Liu, Boxun Lu, Qing Lü, Zhou Songyang, Shuguo Sun et al. · 2024 · Science China Life Sciences
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    Ryohei Watanabe, Shinji Higashi, Takashi Nonaka, Ito Kawakami, Kenichi Oshima, Kazuhiro Niizato, Haruhiko Akiyama, Mari Yoshida, Masato Hasegawa, Tetsuaki Arai · 2020 · Acta Neuropathologica Communications
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    Mercedes Lachén‐Montes, Naroa Mendizuri, Karina Ausín, Pol Andrés‐Benito, Isidró Ferrer, Joaquín Fernández‐Irigoyen, Enrique Santamaría · 2020 · International Journal of Molecular Sciences
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    Priyanka Tripathi, Haihong Guo, Alice Dreser, Alfred Yamoah, Antonio S. Sechi, Christopher Marvin Jesse, Istvan Katona, Panagiotis Doukas, Stefan Nikolin, Sabrina Ernst et al. · 2021 · Cell Death and Disease
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    Shivkumar S. Sammeta, Trupti A. Banarase, Sandip R. Rahangdale, Nitu L. Wankhede, Manish Manohar Aglawe, Brijesh Gulabrao Taksande, Shubhada V Mangrulkar, Aman Babanrao Upaganlawar, Sushruta Koppula, Spandana Rajendra Kopalli et al. · 2023 · Mitochondrion
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    George R. Bjorklund, Jennifer Wong, David A. Brafman, Robert P. Bowser, Sarah E. Stabenfeldt · 2023 · Acta Neuropathologica Communications
30. Overexpression of nuclear FUS induces neuronal cell death
    Hiroaki Suzuki, Masaaki Matsuoka · 2014 · Neuroscience
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    Emma R. Perri, Sonam Parakh, Julie D. Atkin · 2016 · Expert Opinion on Therapeutic Targets
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    Akihiro Sugai, Taisuke Kato, Akihide Koyama, Yuka Mitsuhashi Koike, Sou Kasahara, Takuya Konno, Tomohiko Ishihara, Osamu Onodera · 2018 · Frontiers in Neuroscience
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    Josh Dubnau · 2018 · Current Opinion in Genetics & Development
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    Jean‐Jacques Michaille, Victoria Piurowski, Brooke Rigot, Hesham Kelani, Emily C. Fortman, Esmerina Tili · 2018 · Medicines
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    Joseph Liang, Issa A. McKinnon, Catharine H. Rankin · 2020 · Journal of Neurogenetics
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    Yi Zeng, Anastasiia Lovchykova, Tetsuya Akiyama, Chang Liu, Caiwei Guo, Vidhya Maheswari Jawahar, Odilia Sianto, Anna Calliari, Mercedes Prudencio, Dennis W. Dickson et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
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    Qian Zhang, Tianjiao Li, Mengying Xu, Binish Islam, Jianwu Wang · 2024 · Cellular and Molecular Neurobiology
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    Jinbin Zhai, L. Zhang, Jelena Mojsilovic‐Petrovic, X. Jian, J. Thomas, Kengo Homma, A. Schmitz, Michael Famulok, Hidenori Ichijo, Yair Argon et al. · 2015 · Journal of Neuroscience
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    Kyota Yasuda, Stavroula Mili · 2016 · Wiley Interdisciplinary Reviews - RNA
40. The NGS technology for the identification of genes associated with the ALS. A systematic review
    Valentina Pecoraro, Jessica Mandrioli, Chiara Carone, Adriano Chiò, Bryan J. Traynor, Tommaso Trenti · 2020 · European Journal of Clinical Investigation
41. Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid–liquid phase separation and aggregation
    Veronica H. Ryan, Scott Watters, Joshua Amaya, Balabhadra Khatiwada, Vincenzo Venditti, Mandar T. Naik, Nicolas Lux Fawzi · 2020 · Nucleic Acids Research
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    Vidhya Bharathi, Amandeep Girdhar, Basant Kumar Patel · 2021 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
43. TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6
    Erik M. Lehmkuhl, Suvithanandhini Loganathan, Eric B. Alsop, Alexander D. Blythe, Tina Kovalik, Nicholas P. Mortimore, Dianne Barrameda, Chuol Kueth, Randall J. Eck, Bhavani Bagevalu Siddegowda et al. · 2021 · Acta Neuropathologica Communications
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    Yuan Chao Xue, Huitao Liu, Yasir Mohamud, Amirhossein Bahreyni, Jingchun Zhang, Neil R. Cashman, Honglin Luo · 2022 · Journal of Neuroinflammation
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    Ariel Ionescu, Topaz Altman, Eran Perlson · 2023 · Molecular Neurodegeneration
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    Lucio Tremolizzo, Emanuela Laura Susani, Christian Lunetta, Massimo Corbo, Carlo Ferrarese, Ildebrando Marco Appollonio · 2014 · Journal of Neurology
49. Molecular chaperone HSP70 prevents formation of inclusion bodies of the 25-kDa C-terminal fragment of TDP-43 by preventing aggregate accumulation
    Akira Kitamura, Nodoka Iwasaki, Masataka Kinjo · 2018 · Cell Stress and Chaperones
50. Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases
    Roberta Cascella, Giulia Fani, Alessandra Bigi, Fabrizio Chiti, Cristina Cecchi · 2019 · International Journal of Molecular Sciences
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    Ryan J. H. West, Chris Ugbode, Laura Fort‐Aznar, Sean T. Sweeney · 2020 · Neurobiology of Disease
52. Gene Expression Signatures of Sporadic ALS Motor Neuron Populations
    Ranjan Batra, Kasey R. Hutt, Anthony Q. Vu, Stuart J. Rabin, Michael W. Baughn, Ryan T. Libby, Shawn S. Hoon, John Ravits, Gene Wei-Ming Yeo · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
53. Longitudinal diffusion tensor imaging resembles patterns of pathology progression in behavioral variant frontotemporal dementia (BVFTD)
    Kassubek, Jan, Müller, Hans-Peter, Del Tredici, Kelly, Hornberger, Michael, Schroeter, Matthias L., Müller, Karsten, Anderl-Straub, Sarah, Uttner, Ingo, Grossman, Murray, Braak, Heiko et al. · 2018 · Frontiers in Aging Neuroscience
54. Co-Aggregation of TDP-43 with Other Pathogenic Proteins and Their Co-Pathologies in Neurodegenerative Diseases
    Lei‐Lei Jiang, Xiang-Le Zhang, Hongyu Hu · 2024 · International Journal of Molecular Sciences
55. Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial
    Brittany N. Flores, Seungyoon B. Yu, Isaac V. Cohen, Melania H. Fanok, Wei Luan, Romeo D. Maciuca, Linus D. Sun, Richard M. Tsai, Maurits F. J. M. Vissers, Lars Smits et al. · 2025 · Nature Communications
56. Amyotrophe Lateralsklerose
    Annemarie Hübers, Albert Christian Ludolph, Angela Rosenbohm, Elmar Hans Pinkhardt, Jochen Hans Weishaupt, Johannes Dorst · 2015 · Der Nervenarzt
57. Conserved metabolite regulation of stress granule assembly via AdoMet
    Kyle Begovich, Anthony Q. Vu, Gene Wei-Ming Yeo, James E. Wilhelm · 2020 · The Journal of Cell Biology
58. Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations
    Shio Mitsuzawa, Naoki Suzuki, Tetsuya Akiyama, Mitsuru Ishikawa, Takefumi Sone, Jiro Kawada, Ryo Funayama, Matsuyuki Shirota, Hiroaki Mitsuhashi, Satoru Morimoto et al. · 2021 · Stem Cell Reports
59. The ESCRT-III protein VPS4, but not CHMP4B or CHMP2B, is pathologically increased in familial and sporadic ALS neuronal nuclei
    Alyssa N. Coyne, Jeffrey D. Rothstein · 2021 · Acta Neuropathologica Communications
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    Sunandini Chandra, C. Patrick Lusk · 2022 · International Journal of Molecular Sciences
61. Targeting ER-Mitochondria Signaling as a Therapeutic Target for Frontotemporal Dementia and Related Amyotrophic Lateral Sclerosis
    Sandra M. Martín‐Guerrero, Andrea Markovinović, Gábor M. Mórotz, Shaakir Salam, Wendy J. Noble, Christopher C.J. Miller · 2022 · Frontiers in Cell and Developmental Biology
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    Su Min Lim, Minyeop Nahm, Seung Hyun Kim · 2023 · Journal of Clinical Neurology
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    Nicole Scott‐Hewitt, Youtong Huang, Beth Stevens · 2023 · Annals of the New York Academy of Sciences
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    Ileana Lorenzini, Eric B. Alsop, Jennifer Levy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow, Stephen R. Moore, Ryan S. Pevey, Lynette M. Bustos, Camelia Burciu et al. · 2023 · Frontiers in Cellular Neuroscience
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    Maize C. Cao, Brigid Ryan, Jane Wu, Maurice A. Curtis, Richard L. M. Faull, Mike Dragunow, Emma L. Scotter · 2023 · Neurobiology of Disease
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    Francesca Trojsi, Pierpaolo Sorrentino, Giuseppe Sorrentino, Gioacchino Tedeschi · 2017 · CNS Spectrums
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    Sean M. Cascarina, Kacy R. Paul, Satoshi Machihara, Eric D. Ross · 2018 · PLoS Genetics
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    Rosa Rademakers, Marka van Blitterswijk · 2014 · Neuron
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     Luke McAlary, Justin J. Yerbury, Neil R. Cashman · 2020 · Progress in molecular biology and translational science