Diverse Spatial Reference Frames of Vestibular Signals in Parietal Cortex
Open accessAbstract
Reference frames are important for understanding how sensory cues from different modalities are coordinated to guide behavior, and the parietal cortex is critical to these functions. We compare reference frames of vestibular self-motion signals in the ventral intraparietal area (VIP), parietoinsular vestibular cortex (PIVC), and dorsal medial superior temporal area (MSTd). Vestibular heading tuning in VIP is invariant to changes in both eye and head positions, indicating a body (or world)-centered reference frame. Vestibular signals in PIVC have reference frames that are intermediate between head and body centered. In contrast, MSTd neurons show reference frames between head and eye centered but not body centered. Eye and head position gain fields were strongest in MSTd and weakest in PIVC. Our findings reveal distinct spatial reference frames for representing vestibular signals and pose new challenges for understanding the respective roles of these areas in potentially diverse vestibular functions.
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Compared to F4, VIP receives prominent vestibular input, suggesting it integrates relevant information from head motion and ego-motion in space.
“Compared to F4, VIP receives also prominent vestibular input, suggesting that it integrates relevant information from head motion, and, in general, ego-motion in space (Chen et al. 2011a, b, 2013).”
From Neuroanatomical correlates of peripersonal space: bridging the gap between perception, action, emotion and social cognition (2024) · cites this paper as Chen et al. 2011a, b, 2013
The Results and the Discussion section on body-centered vestibular signals report vestibular heading tuning in VIP and a transformation of head-centered inputs toward a body-centered representation, supporting the suggested role in self-motion processing. The paper does not compare VIP’s vestibular input with F4, so that part of the claim is unsupported. (LLM, conf=0.85)
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- Authors
- Chen, X., DeAngelis, G. C., & Angelaki, D. E.
- Affiliations
- Baylor College of Medicine (US)
- University of Rochester (US)
- Corresponding author
- Angelaki, Dora E.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2013-12
- Volume
- 80
- Issue
- 5
- Pages
- 1310-1321
- ISSN
- 0896-6273 (ISSN-L)
- PMC
- PMC3858444
- OpenAlex
- W2078450002
- Cited by
- 94
- References
- 79
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 6 · 2023: 8 · 2022: 4 · 2021: 8 · 2020: 8 · 2019: 8 · 2018: 14 · 2017: 6 · 2016: 7 · 2015: 6 · 2014: 6 · 2013: 3
- FWCI
- 4.11
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Eye Institute (R01EY017866, R01EY016178)
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Multisensory perception and integration
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Keywords
- spatial reference frames, parietal cortex, ventral intraparietal area, body-centered reference frame, multisensory integration
- MeSH terms
- Action Potentials, Afferent Pathways, Animals, Brain Mapping, Eye Movements, Macaca mulatta, Male, Motion Perception, Nerve Net, Parietal Lobe, Photic Stimulation, Vestibule, Labyrinth, Nystagmus, Optokinetic, Head Movements
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