Neural Circuit Reprogramming: A New Paradigm for Treating Neuropsychiatric Disease?
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Theoretically, harnessing the brain's own endogenous plasticity mechanisms could serve to alter both internal states and external behavior in a therapeutic manner.
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To improve treatment strategies for anxiety, a thorough understanding of the neural circuits governing this emotional state in health and disorder is needed.
“To improve treatment strategies for anxiety, a thorough understanding of the neural circuits governing this emotional state in health and disorder is needed20.”
From Resolving the neural circuits of anxiety (2015) · cites this paper as [20]
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Resolving the neural circuits of anxiety
Calhoon, G. G., & Tye, K. M. (2015) · Nature Neuroscience · doi:10.1038/nn.4101 · Cited by 766 · see citing works
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- Authors
- Tye, K. M.
- Affiliations
- Massachusetts Institute of Technology (US)
- Corresponding author
- Tye, Kay M.
- ORCID
- Tye, Kay M.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2014-09
- Volume
- 83
- Issue
- 6
- Pages
- 1259-1261
- ISSN
- 0896-6273 (ISSN-L)
- PMC
- PMC4565154
- OpenAlex
- W2026163175
- Cited by
- 21
- References
- 21
- Citations by year
- 2026: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 4 · 2019: 1 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 7
- FWCI
- 1.37
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- DSpace@MIT (Massachusetts Institute of Technology) (submittedVersion, cc-by-nc-nd)
- Funders
- National Alliance for Research on Schizophrenia and Depression
- National Institute on Aging (RF1AG047661, RF1-AG047661-01)
- National Institute of Mental Health (R01MH102441, R01‐MH102441‐01)
- National Institute of Diabetes and Digestive and Kidney Diseases (DP2-DK-102256-01, DP2DK102256)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- neuropsychiatric disorders, behavior modification, internal state
- MeSH terms
- Animals, Mental Disorders, Humans, Neuronal Plasticity, Optogenetics
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