The DOI matches its Crossref record; 138 of the 138 references it cites were found in a registry or an index.
How Can Hearing Loss Cause Dementia?
Open accessAbstract
Epidemiological studies identify midlife hearing loss as an independent risk factor for dementia, estimated to account for 9% of cases. We evaluate candidate brain bases for this relationship. These bases include a common pathology affecting the ascending auditory pathway and multimodal cortex, depletion of cognitive reserve due to an impoverished listening environment, and the occupation of cognitive resources when listening in difficult conditions. We also put forward an alternate mechanism, drawing on new insights into the role of the medial temporal lobe in auditory cognition. In particular, we consider how aberrant activity in the service of auditory pattern analysis, working memory, and object processing may interact with dementia pathology in people with hearing loss. We highlight how the effect of hearing interventions on dementia depends on the specific mechanism and suggest avenues for work at the molecular, neuronal, and systems levels to pin this down.
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Cites
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Cited by
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Visual impairment, eye diseases, and dementia risk: a systematic review and meta-analysis
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Aging-associated sensory decline and Alzheimer’s disease
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Sensory processing deficits and related cortical pathological changes in Alzheimer’s disease
Zhang, N. K., Zhang, S. K., Zhang, L. I., Tao, H. W., & Zhang, G.-W. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2023.1213379 · Cited by 49
Metadata
- Authors
- Griffiths, T. D., Lad, M., Kumar, S., Holmes, E., McMurray, B., Maguire, E. A., Billig, A. J., & Sedley, W.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2020-11
- Volume
- 108
- Issue
- 3
- Pages
- 401-412
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W3082818205
- Cited by
- 369
- References
- 138
- FWCI
- 20.66
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
