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Cited by 164Posttraumatic Stress Disorder ResearchTraumatic Brain Injury ResearchPain Management and Treatment

The DOI matches its Crossref record; 189 of the 191 references it cites were found in a registry or an index.

Pain and post traumatic stress disorder - review of clinical and experimental evidence

Moeller-Bertram, Tobias, Keltner, John, Strigo, Irina A.·2012·Neuropharmacology
DOI 10.1016/j.neuropharm.2011.04.028
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Abstract

Pain and Post Traumatic Stress Disorder (PTSD) are highly comorbid conditions. Patients with chronic pain have higher rates of PTSD. Likewise, patients with PTSD are often diagnosed with numerous chronic pain conditions. Despite the high pain-PTSD comorbidity, the neurobehavioral mechanisms underlying this phenomenon are incompletely understood and only recently researchers have started investigating it using experimental models. In this article, we systematically review the substantial clinical evidence on the co-occurrence of pain and PTSD, and the limited experimental evidence of pain processing in this disorder. We provide a detailed overview of the psychophysical and brain imaging experiments that compared somatosensory and pain processing in PTSD and non-PTSD populations. Based on the presented evidence, an extensive body of literature substantiates the clinical coexistence of pain and PTSD in patients but the limited experimental data show inconsistent results highlighting the need for well-controlled future studies. This article is part of a Special Issue entitled 'Post-Traumatic Stress Disorder'.

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Crossref · 10.1016/j.neuropharm.2011.04.028

Cites

189 of 189 references verified0 citation errors · 0 not checkable

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Citations

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Show all 191 references

Research works printed but not linked: 7

  1. Bremner, 2003, Assessment of the Hypothalamic-Pituitary-Adrenal axis over a 24-Hour diurnal period and in response to neuroendocrine challenges in women with and without childhood sexual abuse and posttraumatic, Biol. Psychiatry, 54, 710, 10.1016/S0006-3223(02)01912-1 · DOI
  2. Coffey, 2006, Screening for PTSD in motor vehicle accident survivors using the PSS-SR and IES.J. Trauma, Stress, 19, 119
  3. Kessler, 1995, Posttraumatic stress disorder in the National Comorbidity Survey, Arch. Gen. Psychiatry, 52, 1048, 10.1001/archpsyc.1995.03950240066012 · DOI · Paper page
  4. De Leeuw, 2005, Prevalence of post-traumatic stress disorder symptoms in orofacial pain patients. Oral Surg. Oral Med. Oral Pathol. Oral Radiol, Endod., 99, 558
  5. Millan, 1999, The induction of pain: an integrative review. Prog, Neurobiol., 57, 1
  6. Sessle, 1990, Central nervous system mechanisms of muscular pain. Adv. Pain Res, Ther, 17, 87
  7. Van Loey, 2003, Predictors of chronic posttraumatic stress symptoms following burn injury: results of a longitudinal study, J. Trauma. Stress, 16, 361, 10.1023/A:1024465902416 · DOI

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Metadata

Authors
Moeller-Bertram, T., Keltner, J., & Strigo, I. A.
Affiliations
University of California San Diego (US)
ORCID
Venue
Neuropharmacology
Publisher
Elsevier BV
Published
2012-02
Volume
62
Issue
2
Pages
586-597
ISSN
0028-3908 (ISSN-L)
DOI
10.1016/j.neuropharm.2011.04.028
OpenAlex
W2021224881
Cited by
163
References
191
Citations by year
2026: 2 · 2025: 10 · 2024: 7 · 2023: 10 · 2022: 16 · 2021: 6 · 2020: 12 · 2019: 10 · 2018: 9 · 2017: 13 · 2016: 22 · 2015: 13 · 2014: 18 · 2013: 10 · 2012: 5
FWCI
1.58
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Neuropharmacology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
  • Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
Keywords
post-traumatic stress disorder, chronic pain, pain processing, somatosensory processing, neuroimaging, psychophysical experiments, neurobehavioral mechanisms
MeSH terms
Brain, Humans, Pain, Stress Disorders, Post-Traumatic, Pain Threshold, Neuroimaging

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