The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
The ability to decide advantageously declines prematurely in some normal older persons
Abstract
The prefrontal region of the brain, including the ventromedial sector which supports reasoning and decision-making, may undergo disproportionate aging in some older persons, but the empirical evidence is decidedly mixed. To help resolve this, we tested 80 neurologically and psychiatrically healthy Younger (aged 26-55) and Older (aged 56-85) adults on a "Gambling Task", which provides a close analog to real-world decision-making by factoring in reward, punishment, and unpredictability, yielding a sensitive index of ventromedial prefrontal function. A subset of the Older group manifested a decision-making impairment on the Gambling Task, in spite of otherwise intact cognitive functioning. This finding raises the possibility of disproportionate aging of the ventromedial prefrontal cortex in these individuals. Our finding has important societal and public policy implications (e.g., choosing medical care, allocating personal wealth), and may also help explain why many older individuals are targeted by and susceptible to fraudulent advertising.
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“When examining individual responses, the authors reported that among the younger group, 37 out of 40 participants eventually picked from the advantaged deck; among the older group, only 15 out of 40 showed this same “unimpaired” pattern.”
From More than a feeling: A unified view of stress measurement for population science (2018) · cites this paper as Denburg et al., 2005
In the citing paper
“In the extension of this earlier study with older adults, similar to the studies on patients with VM lesions, they did not show preferences for the advantageous decks across five trials (or 100 cards; Denburg et al., 2005).”
From More than a feeling: A unified view of stress measurement for population science (2018) · cites this paper as Denburg et al., 2005
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Cites
Nonparametric Statistics for the Behavioral Sciences
Guitton, H., & Siegel, S. (1958) · Revue économique · doi:10.2307/3498751 · Cited by 35,279
Nonparametric statistics for the behavioral sciences
McGinn, L. C. (1957) · Journal of the Franklin Institute · doi:10.1016/0016-0032(57)90766-4 · Cited by 7,284
Insensitivity to future consequences following damage to human prefrontal cortex
Bechara, A., Damasio, A. R., Damasio, H., & Anderson, S. W. (1994) · Cognition · doi:10.1016/0010-0277(94)90018-3 · Cited by 6,128
Self-citationEmotion, Decision Making and the Orbitofrontal Cortex
Bechara, A. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.295 · Cited by 3,589
Self-citationAn application of prefrontal cortex function theory to cognitive aging.
West, R. L. (1996) · Psychological Bulletin · doi:10.1037/0033-2909.120.2.272 · Cited by 2,157
Stuss, D. T., & Benson, D. F. (1986) · Raven Press eBooks · Cited by 2,102
The handbook of aging and cognition
Craik, F. I. M., & Salthouse, T. A. (1992) · doi:10.4324/9781410601988 · Cited by 2,064
Bechara, A., Tranel, D., & Damásio, H. (2000) · Brain · doi:10.1093/brain/123.11.2189 · Cited by 1,903
Self-citationThe Handbook of aging and cognition
(1993) · Choice Reviews Online · doi:10.5860/choice.30-3520 · Cited by 1,603
Longitudinal Magnetic Resonance Imaging Studies of Older Adults: A Shrinking Brain
Resnick, S. M., Pham, D. L., Kraut, M. A., Zonderman, A. B., & Davatzikos, C. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-08-03295.2003 · Cited by 1,425
Research works printed but not linked: 1
- Denburg, 2001, Iowa gambling task performance in elderly persons predicts susceptibility to the influence of misleading advertising, Society for Neuroscience, 27
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Religious Orders Study and Rush Memory and Aging Project
Bennett, D. A., Buchman, A. S., Boyle, P. A., Barnes, L. L., Wilson, R. S., & Schneider, J. A. (2018) · Journal of Alzheimer's Disease · doi:10.3233/jad-179939 · Cited by 1,260
More than a feeling: A unified view of stress measurement for population science
Epel, E. S., Crosswell, A. D., Mayer, S. E., Prather, A. A., Slavich, G. M., Puterman, E., & Mendes, W. B. (2018) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2018.03.001 · Cited by 1,077
“In the extension of this earlier study with older adults, similar to the studies on patients with VM lesions, they did not show preferences for the advantageous decks across five trials (or 100 cards; Denburg et al., 2005).”
BackgroundResultThe somatic marker hypothesis: A critical evaluation
Dunn, B. D., Dalgleish, T., & Lawrence, A. D. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.07.001 · Cited by 894
The Age of Reason: Financial Decisions over the Life Cycle and Implications for Regulation
Agarwal, S. D., Driscoll, J. C., Gabaix, X., & Laibson, D. (2009) · Brookings Papers on Economic Activity · doi:10.1353/eca.0.0067 · Cited by 849
Brand, M., Recknor, E. C., Fabian Grabenhorst, B., & Bechara, A. (2006) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390500507196 · Cited by 553
Self-citation
Metadata
- Authors
- Denburg, N. L., Tranel, D., & Bechara, A.
- Affiliations
- University of Iowa (US)
- Corresponding author
- Denburg, N.L.
- Venue
- Neuropsychologia
- Publisher
- Elsevier BV
- Published
- 2005-01
- Volume
- 43
- Issue
- 7
- Pages
- 1099-1106
- ISSN
- 0028-3932 (ISSN-L)
- OpenAlex
- W1984128842
- Cited by
- 310
- References
- 38
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 4 · 2023: 4 · 2022: 7 · 2021: 15 · 2020: 10 · 2019: 9 · 2018: 21 · 2017: 10 · 2016: 17 · 2015: 18 · 2014: 19 · 2013: 21 · 2012: 31
- FWCI
- 3.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropsychologia (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Aging (K01AG022033)
- National Institute of Neurological Disorders and Stroke (P01 NS19632, P01NS019632)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
- Social Sciences › Psychology › Clinical Psychology › Historical and Modern Theater Studies
- Keywords
- decision-making, ventromedial prefrontal cortex, brain aging, older adults, gambling task, cognitive aging, reward and punishment, fraud susceptibility, normal aging
- MeSH terms
- Adult, Aged, Aged, 80 and over, Aging, Analysis of Variance, Cognition, Decision Making, Female, Gambling, Games, Experimental, Humans, Male, Middle Aged, Reference Values, Prefrontal Cortex
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