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Dendritic spine changes associated with normal aging
Open accessAbstract
Given the rapid rate of population aging and the increased incidence of cognitive decline and neurodegenerative diseases with advanced age, it is important to ascertain the determinants that result in cognitive impairment. It is also important to note that much of the aged population exhibit 'successful' cognitive aging, in which cognitive impairment is minimal. One main goal of normal aging studies is to distinguish the neural changes that occur in unsuccessful (functionally impaired) subjects from those of successful (functionally unimpaired) subjects. In this review, we present some of the structural adaptations that neurons and spines undergo throughout normal aging and discuss their likely contributions to electrophysiological properties and cognition. Structural changes of neurons and dendritic spines during aging, and the functional consequences of such changes, remain poorly understood. Elucidating the structural and functional synaptic age-related changes that lead to cognitive impairment may lead to the development of drug treatments that can restore or protect neural circuits and mediate cognition and successful aging.
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Cites
Life and Death of Neurons in the Aging Brain
Morrison, J. H., & Hof, P. R. (1997) · Science · doi:10.1126/science.278.5337.412 · Cited by 1,344
Self-citationInfluence of dendritic structure on firing pattern in model neocortical neurons
Mainen, Z. F., & Sejnowski, T. J. (1996) · Nature · doi:10.1038/382363a0 · Cited by 1,231
Executive Functioning as a Potential Mediator of Age-Related Cognitive Decline in Normal Adults.
Salthouse, T. A., Atkinson, T. M., & Berish, D. E. (2003) · Journal of Experimental Psychology: General · doi:10.1037/0096-3445.132.4.566 · Cited by 1,057
Liston, C., Miller, M. M., Goldwater, D. S., Radley, J. J., Rocher, A. B., Hof, P. R., Morrison, J. H., & McEwen, B. S. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1184-06.2006 · Cited by 968
Self-citationThe ageing cortical synapse: hallmarks and implications for cognitive decline
Morrison, J. H., & Baxter, M. G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3200 · Cited by 965
Radley, J. J., Sisti, H. M., Hao, J., Rocher, A. B., McCall, T., Hof, P. R., McEwen, B. S., & Morrison, J. H. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.01.006 · Cited by 769
Self-citationAge-Related Impairment in Executive Functioning: Updating, Inhibition, Shifting, and Access
Fisk, J. E., & Sharp, C. A. (2004) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803390490510680 · Cited by 634
Propagation of action potentials in dendrites depends on dendritic morphology
Vetter, P., Roth, A., & Häusser, M. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.2.926 · Cited by 598
The effects of normal aging on myelin and nerve fibers: a review
Peters, A. (2002) · Journal of Neurocytology · doi:10.1023/a:1025731309829 · Cited by 577
Neuronal basis of age-related working memory decline
Wang, M., Gamo, N. J., Yang, Y., Jin, L. E., Wang, X.-J., Laubach, M., Mazer, J. A., Lee, D., & Arnsten, A. F. T. (2011) · Nature · doi:10.1038/nature10243 · Cited by 485
Research works printed but not linked: 1
- De Groot, 1987, Numerical changes in rat hippocampal synapses: an effect of “aging”?, Acta Stereol, 6, 53
Cited by
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Cognitive Aging and Changes in Brain Morphology
Carroll, M. A. (2018) · Topics in Geriatric Rehabilitation · doi:10.1097/tgr.0000000000000169 · Cited by 3
Age-related decrements in cortical gyrification: Evidence from an accelerated longitudinal datasetPreprint
Madan, C. R. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.03.05.979344 · Cited by 3
Vicidomini, C., Goode, T. D., McAvoy, K. M., Yu, R., Beveridge, C. H., Iyer, S. N., Victor, M. B., Leary, N., Evans, L., Steinbaugh, M. J., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.26.605338 · Cited by 4
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Aguilar‐Hernández, L., Flores‐Gómez, G. D., Nácher, J., Morales‐Medina, J. C., & Flores, G. (2025) · Neurochemical Research · doi:10.1007/s11064-025-04627-0 · Cited by 2
Cheung, N. (2026) · Cureus · doi:10.7759/cureus.111824 · Cited by 3
Rooker, K. D., Hernandez-Vizcarrondo, G. A., Cheung, S. W., Bhat, S. M., Brown, A. D., Sieck, G. C., & Fogarty, M. J. (2026) · Physiological Reports · doi:10.14814/phy2.71035 · Cited by 2
Coad, B. M., Ghomroudi, P. A., Sims, R., Aggleton, J. P., Vann, S. D., & Metzler‐Baddeley, C. (2022) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2022.02.004 · Cited by 2
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Nyberg, L. H., Walhovd, K. B., & Fjell, A. M. (2024) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190917982.013.56 · Cited by 3
Mercado, N. M., Szarowicz, C., Stancati, J. A., Sortwell, C. E., Boezwinkle, S. A., Collier, T. J., Caulfield, M. E., & Steece‐Collier, K. (2024) · npj Parkinson s Disease · doi:10.1038/s41531-024-00771-6 · Cited by 2
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Keary, K. M., Sojka, E., Gonzalez, M., & Li, Z. (2024) · Journal of Visualized Experiments · doi:10.3791/66493 · Cited by 2
Age-related volume decrease in subcortical gray matter is a part of healthy brain aging in men
Perić, R., Romčević, I., Mastilović, M., Starčević, I., & Boban, J. M. (2024) · Irish Journal of Medical Science (1971 -) · doi:10.1007/s11845-024-03840-0 · Cited by 2
Dickstein, D. L., Zhang, R., Ru, N., Vozenin, M., Perry, B. C., Wang, J., Baulch, J. E., Acharya, M. M., & Limoli, C. L. (2025) · Brain Structure and Function · doi:10.1007/s00429-025-02902-y · Cited by 3
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Siu, C. R., Beshara, S. P., Balsor, J. L., Mancini, S. J., & Murphy, K. M. (2018) · Neuromethods · doi:10.1007/978-1-4939-8739-9_15 · Cited by 2
Melatonin changes the electrical spontaneous activity of hippocampal rat neurons at different ages
Pérez-Torres, D., Reyes-Vázquez, C., Velázquez-Paniagua, M., & rieto-Gómez, B. P. (2014) · Advances in Aging Research · doi:10.4236/aar.2014.31006 · Cited by 2
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Davinelli, S., Scapagnini, G., Koverech, G., Luca, M., Calandra, C., & Calabrese, V. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801816-3.00019-4 · Cited by 2
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Vanderlip, C. R., Jutras, M. L., Asch, P. A., Zhu, S. Y., Lerma, M. N., Buffalo, E. A., & Glavis‐Bloom, C. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.22.604411 · Cited by 2
Albertson, A. J., Landsness, E. C., Eisfelder, M., Young, B. M., Judge, B., Brier, M. R., Euler, M. J., Cramer, S. C., Lee, J., & Lohse, K. R. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.07.622359 · Cited by 2
Mohamad, A. M., Hassan, S. A. M., Moussa, E. A., & Mahdy, T. O. E. (2024) · Anatomia Histologia Embryologia · doi:10.1111/ahe.13014 · Cited by 2
Age and associated hypertension impair hippocampal circuitry function and memory
Ratner, M. H., Nist, K. M., Wainford, R. D., & Farb, D. H. (2025) · GeroScience · doi:10.1007/s11357-025-01831-2 · Cited by 1
Brain aging: molecular targets of geroprotection and prevention strategies
Chukanova, E. I., & Сергеевна, Ч. А. (2025) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro2025125111132 · Cited by 1
Merenstein, J. L., Bennett, I. J., & Madden, D. J. (2026) · Human Brain Mapping · doi:10.1002/hbm.70511 · Cited by 1
Cortés-Díaz, D., Jara, C., Fuentes, I., Llanquinao, J., Lira, M., Ricca, M., Valenzuela, S., Oliva, C. A., & Tapia‐Rojas, C. (2026) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2026.03.059 · Cited by 1
Nicolaidou, A. R., el Jundi, B., Rößler, W., & Groh, C. (2026) · The Journal of Comparative Neurology · doi:10.1002/cne.70169 · Cited by 1
Osuru, H. P., Atluri, N., Le, T., Park, J., Jedrusiak, M., Dulko, E., Illendula, M., & Lunardi, N. (2026) · Alzheimer s & Dementia · doi:10.1002/alz.71556 · Cited by 1
Geriatric Anesthesia: Age-Dependent Changes in the Central and Peripheral Nervous Systems
Doshi, A. K., Cabeza, R. E. L., & Berger, M. (2017) · Springer eBooks · doi:10.1007/978-3-319-66878-9_10 · Cited by 1
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Yemişçi, M., & Karataş, H. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-98804-9.00011-6 · Cited by 1
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Izawa, S., Yamada, K., Yao, R., Aizu, N., Kito, T., Iwata, D., Chihara, T., Sawada, H., & Nishii, K. (2022) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000526620 · Cited by 1
Nyberg, L. H. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15754-7.00012-2 · Cited by 1
Defining, Re-defining, and Understanding the Brain and Mental Health During Ageing
Kaur, G., & Rattan, S. I. S. (2024) · Healthy ageing and longevity · doi:10.1007/978-3-031-68513-2_1 · Cited by 2
Krivinko, J. M., Fan, P., Sui, Z., Happe, C. L., Hensler, C., Gilardi, J., Ikonomović, M. D., McKinney, B. C., Newman, J., Ding, Y., et al. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02817-w · Cited by 2
Ivanov, M. V., Kutukova, K. A., & Berezhnaya, L. A. (2017) · Annals of Clinical and Experimental Neurology · doi:10.17816/acen.2017.2.6 · Cited by 1
Porceddu, R., Podda, C., Mulas, G., Palmas, F., Picci, L., Scano, C., Spiga, S., & Sabatini, A. (2022) · Biology · doi:10.3390/biology11081244 · Cited by 2
An insight into plant polyphenols in prevention of brain aging
Singh, P., Konar, A., & Thakur, M. K. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90581-7.00018-9 · Cited by 1
Dendritic and Spine Loss in Epilepsy: What Seizures Got to Do With It?
Aroor, A., & Brewster, A. L. (2021) · Epiliepsy currents/Epilepsy currents · doi:10.1177/15357597211003096 · Cited by 1
The Aging Synapse: An Integrated Proteomic And Transcriptomic AnalysisPreprint
Caterino, C., Ugolini, M., Durso, W., Jevdokimenko, K., Groth, M., Riege, K., Görlach, M., Fornasiero, E. F., Ori, A., Hoffmann, S., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.12.18.629115 · Cited by 1
Rahamon, S. K., Yusuff, A. O., Ayinde, O. O., & Taiwo, F. (2024) · Research Square · doi:10.21203/rs.3.rs-5194167/v1 · Cited by 1
Kawato, S., Hojo, Y., Ogiue‐Ikeda, M., Soma, M., Saito, M., Kim, J., Munetomo, A., Higo, S., Ishii, H., Kato, A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.08.17.670749 · Cited by 1
Phenotypic Impact of Genetic Risk Pathways for Alzheimer's Disease
Felsky, D. (2016) · TSpace (University of Toronto)
Itorralba, J. (2014) · QSpace (Queen's University Library) · doi:10.13140/rg.2.2.17643.28960
Kapadia, F. (2016) · TSpace (University of Toronto)
Beuk, J. (2016) · QSpace (Queen's University Library)
Prenatal Cocaine-Induced Alterations in Dendritic Spine Density and Glutamate Neurotransmission
Frankfurt, M., Otkins, J., & Bakshi, K. P. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803750-8.00025-7
Zhao, Y. (2017) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/k7f47mkc
Prévot, T. D., Sumitomo, A., Tomoda, T., Knutson, D. E., Li, G., Cook, J. M., & Sibille, E. L. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.02.28.964742 · Cited by 1
Hippocampal Synaptic Stability and Plasticity
Rune, G. M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190645908.003.0007
Efeitos neuromodulatórios e neurotróficos da insulina sobre o envelhecimento cerebral
Haas, C. B. (2013) · Americanae (AECID Library)
Huffels, C. F. M., van Dijk, R. E., Karst, H., Meye, F. J., Hol, E. M., & Middeldorp, J. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-220337
Javani, G., Babri, S., Farajdokht, F., Ghaffari‐Nasab, A., & Mohaddes, G. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4191477
Gene-expression control in early and late-onset dementia
Zhou, J. (2022) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-9465
Chemobrain: Mysteries and the importance of their revelation
Tuncer, M. (2022) · Hacettepe University Journal of the Faculty of Pharmacy · doi:10.52794/hujpharm.1100269
Bolotova, V. T., & Шустов, Е. Б. (2019) · ВЕСТНИК ОБРАЗОВАНИЯ И РАЗВИТИЯ НАУКИ РОССИЙСКОЙ АКАДЕМИИ ЕСТЕСТВЕННЫХ НАУК · doi:10.26163/gief.2019.23.1.013
Garin, C. M., & Dhénain, M. (2023) · Scientific Reports · doi:10.1038/s41598-023-33482-8
Nitu, N. S., Sultana, S. Z., Haq, M. A., Sumi, S. A., Bose, S. K., Sinha, S., Kumar, S., & Haque, M. (2023) · Cureus · doi:10.7759/cureus.42103
Passarella, S., Brandes, K., Dankert, E., Cavalli, P., Kröger, A., Dieterich, D. C., & Landgraf, P. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.25.559304
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Schreiber, W. B., & Robinson-Drummer, P. A. (2022) · Journal of Undergraduate Neuroscience Education · doi:10.59390/aoin4016
Effects of Anesthetic Choice on the Incidence of Transcranial-Motor Potential-Induced Oral Trauma
Ndege, M.-R., Clanton, A., Lacy, T., & Doan, A. T. (2024) · The Neurodiagnostic Journal · doi:10.1080/21646821.2024.2319508
Cherdak, M. A. (2023) · Advances in Gerontology · doi:10.1134/s2079057024600198
Ratner, M. H., Wainford, R. D., & Farb, D. H. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.20.599963
3-Nitrotyrosine shortens axons of non-dopaminergic neurons by inhibiting mitochondrial motility
Hirai, M., Suzuki, K., Kassai, Y., & Konishi, Y. (2024) · Neurochemistry International · doi:10.1016/j.neuint.2024.105832
Medalla, M., & Luebke, J. I. (2024) · Neuromethods · doi:10.1007/978-1-0716-4019-7_10
Self-citationSahay, A., Vicidomini, C., Goode, T. D., McAvoy, K. M., Yu, R., Beveridge, C. H., Iyer, S. N., Victor, M. B., Leary, N., Steinbaugh, M. J., et al. (2024) · Research Square · doi:10.21203/rs.3.rs-4920738/v1
Шабалин, В. Н., & Shatokhina, S. N. (2024) · Bulletin of the Medical Institute REAVIZ (REHABILITATION DOCTOR AND HEALTH) · doi:10.20340/vmi-rvz.2024.3.ozoz.3
Chaudhry, T., Munguti, J. K., & Idenya, P. M. (2024) · Anatomy & Cell Biology · doi:10.5115/acb.24.088
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Ugidos, I. F., Iglesias, J., Milanes, S., Farahani, F., & Mostany, R. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.02.673642
Albertson, A. J., Landsness, E. C., Eisfelder, M., Young, B. M., Judge, B., Brier, M. R., Euler, M. J., Cramer, S. C., Lee, J., & Lohse, K. R. (2025) · Experimental Physiology · doi:10.1113/ep093171 · Cited by 4
Intact corticostriatal function in aged system xc- - deficient mice
Pauw, L. D., Villers, A., Moore, C., Lara, O., Vanonckelen, O., Verbruggen, L., Sato, H., Bentea, E., Arckens, L., Ris, L., et al. (2025) · Translational Psychiatry · doi:10.1038/s41398-025-03686-9
Dolatjavid, F., Farhood, B., Atlasi, M. A., Aliasgharzadeh, A., Mohseni, M., obeidavi, E., & Moradi, H. (2025) · Polish Journal of Medical Physics And Engineering · doi:10.2478/pjmpe-2025-0032
Neurological aging and neurodegenerative disease in humans and great apes
Edler, M. K., Hearn, C. J., Guevara, E. E., Mhatre‐Winters, I., Varghese, M., Freire‐Cobo, C., Sherwood, C. C., Richardson, J. R., Raghanti, M. A., & Hof, P. R. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-27380-3.00074-9
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Koh, J., Lim, W. L., Aquili, L., Blokland, A., Jahanshahi, A., Benazzouz, A., Kocabıçak, E., Temel, Y., Kalueff, A. V., & Lim, L. W. (2026) · Elsevier eBooks · doi:10.1016/b978-0-323-99742-3.00012-6
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Lee, H., Kim, M., Park, I., Cho, S., & Kim, M. J. (2026) · Applied Biological Chemistry · doi:10.1186/s13765-026-01081-6
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Barnes, C. A., Srivathsa, S., Hill, P. F., Srokova, S., & Ekstrom, A. D. (2026) · Springer eBooks · doi:10.1007/978-3-032-20563-6_13 · Cited by 1
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Courtes, M. (2021) · theses.fr (ABES) · doi:10.70675/947b1de8z0429z434ezbf97z16e00e3b7f1a
Albertson, A. J., Bowen, R. M., Ayoub, K., León-Alvarado, R. A., Wang, B., Pati, R., Bauer, A. Q., & Lee, J. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.04.24.720447
Neuron Degeneration During Brain Ageing: Cellular Mechanisms Similar to Neurodegenerative Disease
Fauquier, A., & Sherrard, R. M. (2026) · Contemporary clinical neuroscience · doi:10.1007/978-3-032-18296-8_23
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Gershteyn, I. M., Markov, N. T., Olzinski, M., Kramer, J., Casaletto, K. B., Ellerby, L., & Furman, D. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.22.727307
Caligiuri, C., Feroleto, C., Morotti, M., Codazzi, C., Frasca, F., Cacciotti, A., D’Amelio, C., D’Alelio, F., Paoletti, I., Leone, L., et al. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27146297 · Cited by 1
Llanes-Cervantes, B. A., Cruz-Ramos, J. A., Barón-Cárdenas, M. E., Zepeda-Olmos, P. M., Verdín, S. L., López, J. M. V., & Jimenez, E. D. L. M. (2026) · Brain Sciences · doi:10.3390/brainsci16070765 · Cited by 1
Mechanobiological changes in the aging brain
서은우, & Kim, H. N. (2026) · Mechanobiology · doi:10.1177/29780241261460633
Next-Generation Stroke Biomarkers: Bridging the Gap Between Innovation and Translation
Conti, E., Baldereschi, M., Carlo, A. D., Barbieri, G., Pavone, F. S., Gori, A. M., & Giusti, B. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15166249
Ivanov, I., Džinalija, N., Abe, Y., Alonso, P., Ameis, S. H., Arnold, P. D., Baker, J. T., Balachander, S., Banaj, N., Bargalló, N., et al. (2026) · Cortex · doi:10.1016/j.cortex.2026.08.015
Low-Dose Digoxin Ameliorates Age-Related Motor Learning Deficits in Mice
Hashimoto, J., Kai, M., Matsumoto-Miyai, K., & Kondo, M. (2026) · Neurochemical Research · doi:10.1007/s11064-026-04887-4
Bangera, H., Dafale, R. S., Rao, V. K., Kumar, S. P., Mohandas Rao, K. G., & Manjula, S. D. (2026) · Translational Research in Anatomy · doi:10.1016/j.tria.2026.100521
Zhan, X., Tan, P., Tan, T., & Chen, C.-C. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1932616
The endocannabinoid system and the ageing brain
Zimmer, A. (2026) · Nature reviews. Neuroscience · doi:10.1038/s41583-026-01085-7
Rega, M. (2015) · UCL Discovery (University College London)
Metadata
- Authors
- Dickstein, D. L., Weaver, C. M., Luebke, J. I., & Hof, P. R.
- Affiliations
- Icahn School of Medicine at Mount Sinai (US)
- Franklin & Marshall College (US)
- Boston University (US)
- Corresponding author
- Dickstein, D.L.
- Venue
- Neuroscience
- Publisher
- Elsevier BV
- Published
- 2013-10
- Volume
- 251
- Pages
- 21-32
- ISSN
- 0306-4522 (ISSN-L)
- PMC
- PMC3654095
- OpenAlex
- W1983509957
- Cited by
- 289
- References
- 115
- Citations by year
- 2026: 25 · 2025: 22 · 2024: 41 · 2023: 21 · 2022: 25 · 2021: 29 · 2020: 30 · 2019: 14 · 2018: 22 · 2017: 12 · 2016: 19 · 2015: 9 · 2014: 12 · 2013: 8
- FWCI
- 0.98
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (R01AG035071, AG025062, R01AG025062, P01AG000001, AG035071, AG00001)
- National Institute of Mental Health (MH071818, R01MH071818)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Social Sciences › Psychology › Developmental and Educational Psychology › Aging and Gerontology Research
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- dendritic spines, normal aging, successful aging, cognitive aging, cognitive impairment, synaptic plasticity, electrophysiological properties, neurodegenerative diseases
- MeSH terms
- Aging, Animals, Brain, Cognition, Humans, Neuronal Plasticity, Neurons, Dendritic Spines
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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