Does reactivation trigger episodic memory change? a meta-analysis

Scully, Iiona D.; Napper, Lucy E.; Hupbach, Almut

doi:10.1016/j.nlm.2016.12.012

Cited by 90Memory Processes and InfluencesMemory and Neural MechanismsSleep and Wakefulness Research

Does reactivation trigger episodic memory change? a meta-analysis

Scully, Iiona D., Napper, Lucy E., Hupbach, Almut·2017·Neurobiology of Learning and Memory

DOI 10.1016/j.nlm.2016.12.012

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Abstract

According to the reconsolidation hypothesis, long-term memories return to a plastic state upon their reactivation, leaving them vulnerable to interference effects and requiring re-storage processes or else these memories might be permanently lost. The present study used a meta-analytic approach to critically evaluate the evidence for reactivation-induced changes in human episodic memory. Results indicated that reactivation makes episodic memories susceptible to physiological and behavioral interference. When applied shortly after reactivation, interference manipulations altered the amount of information that could be retrieved from the original learning event. This effect was more pronounced for remote memories and memories of narrative structure. Additionally, new learning following reactivation reliably increased the number of intrusions from new information into the original memory. These findings support a dynamic view of long-term memory by showing that memories can be changed long after they were acquired.

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Authors: Scully, I. D., Napper, L. E., & Hupbach, A.
Affiliations: Lehigh University (US)
Corresponding author: Hupbach, Almut
ORCID: Scully, Iiona D.
Napper, Lucy E.
Hupbach, Almut
Venue: Neurobiology of Learning and Memory
Publisher: Elsevier BV
Published: 2017-07
Volume: 142
Issue: Pt A
Pages: 99-107
ISSN: 1074-7427 (ISSN-L)
DOI: 10.1016/j.nlm.2016.12.012
OpenAlex: W2561994728
Cited by: 90
References: 86
Citations by year: 2026: 3 · 2025: 7 · 2024: 6 · 2023: 4 · 2022: 16 · 2021: 11 · 2020: 13 · 2019: 8 · 2018: 15 · 2017: 7
FWCI: 1.05
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neurobiology of Learning and Memory (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Keywords: memory reconsolidation, memory reactivation, episodic memory, memory interference, remote memory, narrative memory, memory intrusion
MeSH terms: Emotions, Humans, Memory, Long-Term, Memory, Episodic

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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Does reactivation trigger episodic memory change? a meta-analysis

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