Functional brain imaging of placebo analgesia: methodological challenges and recommendations
Abstract
Département de stomatologie, Faculté de médecine dentaire, Université de Montréal, BP 6127, Succursale Centre-ville, Montréal, Que., Canada H3C 3J7 *Corresponding author. Tel.: +514 343 6111x3935. E-mail: [email protected] Submitted and accepted January 12, 2006.
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Pain reports have served as the gold standard measure of pain in clinical settings and experimental studies.
“Pain reports have served as the gold standard measure of pain in clinical settings and experimental studies [64],[65],[78].”
From Distinct Brain Systems Mediate the Effects of Nociceptive Input and Self-Regulation on Pain (2015) · cites this paper as [65]
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“In this context, minimizing differences in the pain experience between conditions could have resulted in lesser effects and differences between control and placebo studies.(19) It has also been hypothesized that placebo effects represent a form of reward expectation processing.”
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“Neuroimaging studies that have focused on expectancy-mediated analgesia reveal that the dorsolateral, orbitofrontal and medial prefrontal cortex may be involved in triggering this form of analgesia (Ploghaus et al., 1999; Wager et al., 2004; Rainville and Duncan, 2006).”
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“…approach, PET, fMRI, magneto-electroencephalography (MEG), and electroencephalography (EEG) have all been usefully employed to characterize the spatial and temporal domains of placebo analgesia (Colloca et al., 2008; Kong, Kaptchuk, Polich, Kirsch, & Gollub, 2007; Rainville & Duncan, 2006).”
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“and electro-encephalography (EEG) have given the opportunity to explore the neuroanatomical bases of placebo analgesia (Rainville and Duncan 2006; Tracey 2005).”
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Naloxone-insensitive Epidural Placebo Analgesia in a Chronic Pain Patient
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- Authors
- Rainville, P., & Duncan, G. H.
- Affiliations
- Université de Montréal (CA)
- Corresponding author
- Rainville, Pierre
- Venue
- Pain
- Published
- 2006-04
- Volume
- 121
- Issue
- 3
- Pages
- 177-180
- ISSN
- 0304-3959 (ISSN-L)
- OpenAlex
- W2021879964
- Cited by
- 26
- References
- 14
- Citations by year
- 2020: 1 · 2015: 2 · 2014: 3 · 2013: 2
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pain (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Pain Management and Placebo Effect
- Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
- Health Sciences › Dentistry › Oral Surgery › Dental Anxiety and Anesthesia Techniques
- Keywords
- placebo analgesia, functional neuroimaging, methodological issues, imaging recommendations, placebo effect, pain perception
- MeSH terms
- Analgesics, Brain, Cerebrovascular Circulation, Clinical Trials as Topic, Humans, Magnetic Resonance Imaging, Neural Pathways, Pain, Placebos, Placebo Effect, Receptors, Opioid, mu, Patient Selection, Positron-Emission Tomography
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