CoChat
Sign Up
Cited by 182Gastrointestinal motility and disordersParkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

The DOI matches its Crossref record; 70 of the 72 references it cites were found in a registry or an index.

Gastroparesis and Parkinson’s disease: A systematic review

Heetun, Zaid S., Quigley, Eamonn M.M.·2012·Parkinsonism & Related Disorders
DOI 10.1016/j.parkreldis.2011.12.004
Open this paper in CoChat — free account

Abstract

Some of the gastrointestinal (GI) symptoms commonly experienced by patients with Parkinson's disease (PD) have been attributed to gastroparesis; however, the precise prevalence and relevance of gastric emptying delay in PD is unclear. The definition of gastroparesis varies; currently the most widely accepted definition (from the National Institute of Diabetes and Digestive and Kidney Diseases Gastroparesis Clinical Research Consortium) is the presence of appropriate symptoms (including nausea, retching, vomiting, stomach fullness, and inability to finish a meal) for ≥ 12 weeks, together with delayed gastric emptying on scintigraphy and the absence of any obstructive lesions on upper GI endoscopy. In PD patients, gastroparesis has the potential to affect nutrition and quality of life, as well as the absorption of PD medications, including L-dopa. This reduced absorption of L-dopa has implications for the control of the PD motor symptoms for which it is administered. We performed a systematic review of the literature on gastroparesis in PD with the aim of developing an evidence-based approach to its management. Based on this review, we conclude that while gastric emptying has been reported to be frequently delayed in PD, the existing data do not permit definitive conclusions concerning its true prevalence, relationship to the underlying disease process, relevance to PD management, or the optimal therapy of related GI symptoms. Further study of these important issues is, therefo…

Overview

Integrity signals

Registry

Crossref · 10.1016/j.parkreldis.2011.12.004

Cites

70 of 70 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

1 retracted

Show all 72 references

Cited by

Sorted by citations

Items 101–182 of 182

Related

See all

Metadata

Authors
Heetun, Z. S., & Quigley, E. M. M.
Affiliations
University College Cork (IE)
Corresponding author
Quigley, Eamonn M.M.
ORCID
Quigley, Eamonn M.M.
Venue
Parkinsonism & Related Disorders
Publisher
Elsevier BV
Published
2012-06
Volume
18
Issue
5
Pages
433-440
ISSN
1353-8020 (ISSN-L)
DOI
10.1016/j.parkreldis.2011.12.004
OpenAlex
W2077886817
Cited by
182
References
72
Citations by year
2026: 10 · 2025: 18 · 2024: 7 · 2023: 16 · 2022: 15 · 2021: 20 · 2020: 12 · 2019: 12 · 2018: 9 · 2017: 13 · 2016: 15 · 2015: 13 · 2014: 11 · 2013: 7 · 2012: 4
FWCI
1.16
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Parkinsonism & Related Disorders (publishedVersion)
  • PubMed (publishedVersion)
Funders
UCB Pharma
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Clinical Neurology › Parkinson's Disease Mechanisms and Treatments
  • Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Keywords
gastroparesis, Parkinson's disease
MeSH terms
Antiparkinson Agents, Humans, Levodopa, Parkinson Disease, Quality of Life, Databases, Bibliographic, Gastroparesis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review