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Cited by 409

The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.

Gene body DNA methylation in plants

Open access
Bewick, Adam J, Schmitz, Robert J·2017·Current Opinion in Plant Biology

Abstract

The type, amount, and location of DNA methylation within a gene provides pivotal information on the enzymatic pathway by which it was achieved and its functional consequences. In plants (angiosperms specifically), gene body methylation (gbM) refers to genes with an enrichment of CG DNA methylation within the transcribed regions and depletion at the transcriptional start and termination sites. GbM genes often compose the bulk of methylated genes within angiosperm genomes and are enriched for housekeeping functions. Contrary to the transcriptionally repressive effects of other chromatin modifications within gene bodies, gbM genes are constitutively expressed. GbM has intrigued researchers since its discovery, and much effort has been placed on identifying its functional role. Here, we highlight the recent findings on the evolutionary origin and molecular mechanism of gbM and synthesize studies describing the possible roles for this enigmatic epigenetic phenotype.

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Metadata

Authors
Bewick, A. J., & Schmitz, R. J.
Venue
Current Opinion in Plant Biology
Publisher
Elsevier BV
Published
2017-04
Volume
36
Pages
103-110
ISSN
1369-5266 (ISSN-L)
OpenAlex
W2592817720
Cited by
409
References
47
FWCI
2.85
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Gene body DNA methylation in plants. https://app.cochat.ai/papers/10.1016/j.pbi.2016.12.007
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Bewick, A. J., & Schmitz, R. J. (2017). Gene body DNA methylation in plants. Current Opinion in Plant Biology. https://doi.org/10.1016/j.pbi.2016.12.007

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