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High level physical activity in cardiac rehabilitation: Implications for exercise training and leisure-time pursuits
Abstract
Importance Regular moderate-to-vigorous physical activity and increased levels of cardiorespiratory fitness (CRF) are widely promoted as cardioprotective measures in secondary prevention interventions. Observations A low level of CRF increases the risk of cardiovascular disease (CVD) to a greater extent than merely being physically inactive. An exercise capacity 3 METs, to empower patients to vacate this "high risk" group. Moreover, a "good" exercise capacity, expressed as peak METs, identifies individuals with a favorable long-term prognosis, regardless of the underlying extent of coronary disease. On the other hand, vigorous-to-high intensity physical activity, particularly when unaccustomed, and some competitive sports are associated with a greater incidence of acute cardiovascular events. Marathon and triathlon training/competition also have limited applicability and value in CR, are associated with acute cardiac events each year, and do not necessarily provide immunity to the development of or the progression of CVD. Furthermore, extreme endurance exercise regimens are associated with an increased incidence of atrial fibrillation and accelerated coronary artery calcification. Conclusions and relevance High-intensity training offers a time-saving alternative to moderate intensity continuous training, as well as other potential advantages. Additional long-term studies assessing safety, adherence, and morbidity and mortality are required before high-intensity CR training ca…
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Due to a lack of data and observation hours in various populations with CVD, it is currently premature to conclude that HIIT is a safe and superior cardiac rehabilitation intervention compared with MICT.
“Based on these findings, it is important to re-emphasize that due to a lack of data and observation hours in various populations with CVD, it is currently premature to conclude that HIIT is a safe and superior CR intervention compared with MICT.”
From Physical activity, cardiorespiratory fitness, and cardiovascular health: A clinical practice statement of the American Society for Preventive Cardiology Part II: Physical activity, cardiorespiratory fitness, minimum and goal intensities for exercise training, prescriptive methods, and special patient populations (2022) · cites this paper as [81]
The patient hours represented within the collective HIIT literature fall short of statistical estimates for the anticipated number of observational hours likely needed to elicit acute cardiac events during HIIT.
“Finally, the patient hours represented within the collective body of literature fall short of statistical estimates for anticipated number of observational hours likely needed to elicit acute cardiac events during HIIT [ 80 , 81 ].”
From Physical activity, cardiorespiratory fitness, and cardiovascular health: A clinical practice statement of the American Society for Preventive Cardiology Part II: Physical activity, cardiorespiratory fitness, minimum and goal intensities for exercise training, prescriptive methods, and special patient populations (2022) · cites this paper as [81]
The phase II patient hours collectively observed in the HIIT-MICT trials published to date represent only a fraction of those expected to result in a cardiac event.
“As indicated earlier, the phase II patient hours collectively observed in the HIIT-MICT trials published to date represent only a fraction of those expected to result in a cardiac event.”
From Physical activity, cardiorespiratory fitness, and cardiovascular health: A clinical practice statement of the American Society for Preventive Cardiology Part II: Physical activity, cardiorespiratory fitness, minimum and goal intensities for exercise training, prescriptive methods, and special patient populations (2022) · cites this paper as [81]
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References 93 · Cited by 18
Research works printed but not linked: 77
- Haskell, 2007, Physical activity and public health: updated recommendation for adults from the American Heart Association, Circulation, 116, 1081, 10.1161/CIRCULATIONAHA.107.185649 · DOI · Paper page
- Swain, 2006, Comparison of cardioprotective benefits of vigorous versus moderate intensity aerobic exercise, Am J Cardiol, 97, 141, 10.1016/j.amjcard.2005.07.130 · DOI · Paper page
- Franklin, 2002, Survival of the fittest: evidence for high-risk and cardioprotective fitness levels, Curr Sports Med Rep, 1, 257, 10.1249/00149619-200210000-00001 · DOI
- Wen, 2011, Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study, Lancet, 378, 1244, 10.1016/S0140-6736(11)60749-6 · DOI · Paper page
- Franklin, 2018, Quantitating the dose of physical activity in secondary prevention: relation of exercise intensity to survival, Mayo Clin Proc, 93, 1158, 10.1016/j.mayocp.2018.07.014 · DOI
- Kokkinos, 2018, Cardiorespiratory fitness and the incidence of chronic disease, J Clin Exerc Physiol, 7, 37, 10.31189/2165-6193-7.2.37 · DOI · Paper page
- Gulati, 2003, Exercise capacity and the risk of death in women: the St. James Women Take Heart Project, Circulation, 108, 1554, 10.1161/01.CIR.0000091080.57509.E9 · DOI · Paper page
- Blair, 1989, Physical fitness and all-cause mortality: a prospective study of healthy men and women, JAMA, 262, 2395, 10.1001/jama.1989.03430170057028 · DOI · Paper page
- Myers, 2002, Exercise capacity and mortality among men referred for exercise testing, N Engl J Med, 346, 793, 10.1056/NEJMoa011858 · DOI · Paper page
- Franklin, 2021, Maximizing the cardioprotective benefits of exercise with age-, sex-, and fitness-adjusted target intensities for training (research letter), Eur J Prev Cardiol
- Kodama, 2009, Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis, JAMA, 301, 2024, 10.1001/jama.2009.681 · DOI · Paper page
- Jae, 2019, Is there an “asymptote of gain” beyond which further increases in cardiorespiratory fitness convey no additional benefits on mortality and atrial fibrillation?, Mayo Clin Proc, 94, 545, 10.1016/j.mayocp.2018.11.023 · DOI
- Feldman, 2015, No evidence of an upper threshold for mortality benefit at high levels of cardiorespiratory fitness, J Am Coll Cardiol, 65, 629, 10.1016/j.jacc.2014.11.030 · DOI
- Martin, 2013, Cardiovascular fitness and mortality after contemporary cardiac rehabilitation, Mayo Clin Proc, 88, 455, 10.1016/j.mayocp.2013.02.013 · DOI · Paper page
- Ross, 2016, Importance of assessing cardiorespiratory fitness in clinical practice: a case for fitness as a clinical vital sign: a scientific statement from the American Heart Association, Circulation, 134, e653, 10.1161/CIR.0000000000000461 · DOI · Paper page
- Eijsvogels, 2018, The “extreme exercise hypothesis”: recent findings and cardiovascular health implications, Curr Treat Options Cardiovasc Med, 20, 84, 10.1007/s11936-018-0674-3 · DOI
- Abdulla, 2009, Is the risk of atrial fibrillation higher in athletes than in the general population? A systematic review and meta-analysis, Europace, 11, 1156, 10.1093/europace/eup197 · DOI · Paper page
- Mont, 2009, Endurance sport practice as a risk factor for atrial fibrillation and atrial flutter, Europace, 11, 11, 10.1093/europace/eun289 · DOI · Paper page
- Wilhelm, 2011, Atrial remodeling, autonomic tone, and lifetime training hours in nonelite athletes, Am J Cardiol, 108, 580, 10.1016/j.amjcard.2011.03.086 · DOI · Paper page
- Möhlenkamp, 2008, Running: the risk of coronary events: prevalence and prognostic relevance of coronary atherosclerosis in marathon runners, Eur Heat J, 29, 1903, 10.1093/eurheartj/ehn163 · DOI · Paper page
- Burtscher, 2000, Prior myocardial infarction is the major risk factor associated with sudden cardiac death during downhill skiing, Int J Sports Med, 21, 613, 10.1055/s-2000-8481 · DOI
- Northcote, 1986, Sudden death and vigorous exercise: a study of 60 deaths associated with squash, Br Heart J, 55, 198, 10.1136/hrt.55.2.198 · DOI
- Link, 2012, Sudden cardiac death in the athlete: bridging the gaps between evidence, policy, and practice, Circulation, 125, 2511, 10.1161/CIRCULATIONAHA.111.023861 · DOI
- Lown, 1977, Neural and psychologic mechanisms and the problem of sudden cardiac death, Am J Cardiol, 39, 890, 10.1016/S0002-9149(77)80044-1 · DOI
- Kim, 2012, Cardiac arrest during long-distance running races, N Engl J Med, 366, 130, 10.1056/NEJMoa1106468 · DOI · Paper page
- Harris, 2017, Death and cardiac arrest in U.S. triathlon participants, 1985 to 2016: a case series, Ann Intern Med, 167, 529, 10.7326/M17-0847 · DOI · Paper page
- Franklin, 1996, Snow shoveling: a trigger for acute myocardial infarction and sudden coronary death, Am J Cardiol, 77, 855, 10.1016/S0002-9149(97)89181-3 · DOI
- Haapaniemi, 2007, Electrocardiographic responses to deer hunting activities in men with and without coronary artery disease, Am J Cardiol, 100, 175, 10.1016/j.amjcard.2007.02.076 · DOI
- Franklin, 1995, Cardiac demands of heavy snow shoveling, JAMA, 273, 880, 10.1001/jama.1995.03520350062030 · DOI
- Chowdhury, 2003, Sudden cardiac death after manual or automated snow removal, Am J Cardiol, 92, 833, 10.1016/S0002-9149(03)00894-4 · DOI
- Thompson, 2007, Exercise and acute cardiovascular events placing the risks into perspective: a scientific statement from the American Heart Association Council on nutrition, physical activity, and metabolism and the council on clinical cardiology, Circulation, 115, 2358, 10.1161/CIRCULATIONAHA.107.181485 · DOI
- Franklin, 1989, Instantaneous electrocardiography: a simple screening technique for cardiac exercise programs, Chest, 96, 174, 10.1378/chest.96.1.174 · DOI
- Pandolf, 1975, Hyperthermia: effect on exercise prescription, Arch Phys Med Rehabil, 56, 524
- Siegel, 2017, Can pre-race aspirin prevent sudden cardiac death during marathons?, Br J Sports Med, 51, 1579, 10.1136/bjsports-2016-096917 · DOI
- Tofler, 1992, Modifiers of timing and possible triggers of acute myocardial infarction in the thrombolysis in myocardial infarction phase II (TIMI II) study group, J Am Coll Cardiol, 20, 1049, 10.1016/0735-1097(92)90356-R · DOI
- Smyth, 2016, Physical activity and anger or emotional upset as triggers of acute myocardial infarction: the INTERHEART study, Circulation, 134, 1059, 10.1161/CIRCULATIONAHA.116.023142 · DOI
- Cardozo, 2015, Effects of high intensity interval versus moderate continuous training on markers of ventilatory and cardiac efficiency in coronary heart disease patients, Scientific World Journal, 2015, 10.1155/2015/192479 · DOI
- Gibala, 2012, Physiological adaptations to low-volume, high-intensity interval training in health and disease, J Physiol, 590, 1077, 10.1113/jphysiol.2011.224725 · DOI · Paper page
- Rognmo, 2004, High intensity aerobic interval exercise is superior to moderate intensity exercise for increasing aerobic capacity in patients with coronary artery disease, Eur J Cardiovasc Prev Rehabil, 11, 216, 10.1097/01.hjr.0000131677.96762.0c · DOI
- Amundsen, 2008, High-intensity aerobic exercise improves diastolic function in coronary artery disease, Scand Cardiovasc J, 42, 110, 10.1080/14017430701744477 · DOI
- Moholdt, 2009, Aerobic interval training versus continuous moderate exercise after coronary artery bypass surgery: a randomized study of cardiovascular effects and quality of life, Am Heart J, 158, 1031, 10.1016/j.ahj.2009.10.003 · DOI
- Jaureguizar, 2016, Effect of high-intensity interval versus continuous exercise training on functional capacity and quality of life in patients with coronary artery disease: a Randomized clinical trial, J Cardiopulm Rehabil Prev, 36, 96, 10.1097/HCR.0000000000000156 · DOI
- Conraads, 2015, Aerobic interval training and continuous training equally improve aerobic exercise capacity in patients with coronary artery disease: the SAINTEX-CAD study, Int J Cardiol, 179, 203, 10.1016/j.ijcard.2014.10.155 · DOI
- Keteyian, 2014, Greater improvement in cardiorespiratory fitness using higher-intensity interval training in the standard cardiac rehabilitation setting, J Cardiopulm Rehabil Prev, 34, 98, 10.1097/HCR.0000000000000049 · DOI
- Pattyn, 2016, The long-term effects of a randomized trial comparing aerobic interval versus continuous training in coronary artery disease patients: 1-year data from the SAINTEX-CAD study, Eur J Prev Cardiol, 23, 1154, 10.1177/2047487316631200 · DOI · Paper page
- Taylor, 2020, Short-term and long-term feasibility, safety, and efficacy of high-intensity interval training in cardiac rehabilitation: the FITR heart study randomized clinical trial, JAMA Cardiol, 5, 1382, 10.1001/jamacardio.2020.3511 · DOI · Paper page
- Dun, 2019, High-intensity interval training in cardiac rehabilitation, Clin Geriatr Med, 35, 469, 10.1016/j.cger.2019.07.011 · DOI · Paper page
- Dun, 2019, High-intensity interval training in cardiac rehabilitation: impact on fat mass in patients with myocardial infarction, Mayo Clin Proc, 94, 1718, 10.1016/j.mayocp.2019.04.033 · DOI
- Dun, 2019, High-intensity interval training improves metabolic syndrome and body composition in outpatient cardiac rehabilitation patients with myocardial infarction, Cardiovasc Diabetol, 18, 104, 10.1186/s12933-019-0907-0 · DOI
- Boidin, 2019, Effects of interval training on risk markers for arrhythmic death: a randomized controlled trial, Clin Rehabil, 33, 1320, 10.1177/0269215519840388 · DOI
- Reed, 2019, The effects of aerobic interval training and moderate-to-vigorous intensity continuous exercise on mental and physical health in women with heart disease, Eur J Prev Cardiol, 26, 211, 10.1177/2047487318795246 · DOI
- Van De Heyning, 2018, Impact of aerobic interval training and continuous training on left ventricular geometry and function: a SAINTEX-CAD substudy, Int J Cardiol, 257, 193, 10.1016/j.ijcard.2017.11.053 · DOI
- Choi, 2018, Superior effects of high-intensity interval training compared to conventional therapy on cardiovascular and psychological aspects in myocardial infarction, Ann Rehabil Med, 42, 145, 10.5535/arm.2018.42.1.145 · DOI
- Ellingsen, 2017, High-intensity interval training in patients with heart failure with reduced ejection fraction, Circulation, 135, 839, 10.1161/CIRCULATIONAHA.116.022924 · DOI · Paper page
- Yardley, 2017, Long-term effects of high-intensity interval training in heart transplant recipients: a 5-year follow-up study of a randomized controlled trial, Clin Transplant, 31, 10.1111/ctr.12868 · DOI
- Warburton, 2005, Effectiveness of high-intensity interval training for the rehabilitation of patients with coronary artery disease, Am J Cardiol, 95, 1080, 10.1016/j.amjcard.2004.12.063 · DOI
- Currie, 2013, Low-volume, high-intensity interval training in patients with CAD, Med Sci Sports Exerc, 45, 1436, 10.1249/MSS.0b013e31828bbbd4 · DOI
- Villelabeitia-Jaureguizar, 2019, Mechanical efficiency of high versus moderate intensity aerobic exercise in coronary heart disease patients: a randomized clinical trial, Cardiol J, 26, 130
- Moholdt, 2012, Aerobic interval training increases peak oxygen uptake more than usual care exercise training in myocardial infarction patients: a randomized controlled study, Clin Rehabil, 26, 33, 10.1177/0269215511405229 · DOI
- Wehmeier, 2020, Effects of high-intensity interval training in a three-week cardiovascular rehabilitation: a randomized controlled trial, Clin Rehabil, 34, 646, 10.1177/0269215520912302 · DOI
- Vanhees, 1994, Prognostic significance of peak exercise capacity in patients with coronary artery disease, J Am Coll Cardiol, 23, 358, 10.1016/0735-1097(94)90420-0 · DOI
- Quindry, 2021, Cardiac rehabilitation and resting blood pressure: Montana outcomes project cardiac rehabilitation registry findings, J Cardiopulm Rehabil Prev
- Way, 2020, The feasibility of implementing high-intensity interval training in cardiac rehabilitation settings: a retrospective analysis, BMC Sports Sci Med Rehabil, 12, 38, 10.1186/s13102-020-00186-9 · DOI
- Moholdt, 2012, Home-based aerobic interval training improves peak oxygen uptake equal to residential cardiac rehabilitation: a randomized, controlled trial, PLoS One, 7, 10.1371/journal.pone.0041199 · DOI
- Torri, 2018, Promotion of home-based exercise training as secondary prevention of coronary heart disease: a pilot web-based intervention, J Cardiopulm Rehabil Prev, 38, 253, 10.1097/HCR.0000000000000316 · DOI
- Cornish, 2011, Interval training for patients with coronary artery disease: a systematic review, Eur J Appl Physiol, 111, 579, 10.1007/s00421-010-1682-5 · DOI
- Siscovick, 1984, The incidence of primary cardiac arrest during vigorous exercise, N Engl J Med, 311, 874, 10.1056/NEJM198410043111402 · DOI · Paper page
- Wisløff, 2007, Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart failure patients: a randomized study, Circulation, 115, 3086, 10.1161/CIRCULATIONAHA.106.675041 · DOI · Paper page
- Sanchis-Gomar, 2021, Exercise effects on cardiovascular disease: from basic aspects to clinical evidence, Cardiovasc Res
- Paluch, 2021, Steps per day and all-cause mortality in middle-aged adults in the coronary artery risk development in young adults study, JAMA Netw Open, 4, 10.1001/jamanetworkopen.2021.24516 · DOI · Paper page
- Jafar, 2019, Assessment of coronary atherosclerosis using calcium scores in short- and long-distance runners, Mayo Clin Proc Innov Qual Outcome, 3, 116, 10.1016/j.mayocpiqo.2019.03.009 · DOI
- Kermott, 2019, Cardiorespiratory fitness and coronary artery calcification in a primary prevention population, Mayo Clin Proc Innov Qual Outcome, 3, 122, 10.1016/j.mayocpiqo.2019.04.004 · DOI
- DeFina, 2019, Association of all-cause and cardiovascular mortality with high levels of physical activity ad concurrent coronary artery calcification, JAMA Cardiol, 4, 174, 10.1001/jamacardio.2018.4628 · DOI · Paper page
- Lavie, 2019, Extreme physical activity and coronary artery calcification-running heavily and safely with “hearts of stone.”, JAMA Cardiol, 4, 182, 10.1001/jamacardio.2018.4647 · DOI
- Lavie, 2019, Extreme physical activity may increase coronary calcification, but fitness still prevails, Mayo Clin Proc Innov Qual Outome, 3, 103, 10.1016/j.mayocpiqo.2019.03.007 · DOI
- Cornelissen, 2017, High intensity interval training in coronary artery disease patients, is it worth the effort?, Eur J Prev Cardiol, 24, 1692, 10.1177/2047487317734051 · DOI
- Elliott, 2015, Interval training versus continuous exercise in patients with coronary artery disease: a meta-analysis, Heart Lung Circ, 24, 149, 10.1016/j.hlc.2014.09.001 · DOI
Metadata
- Authors
- Franklin, B. A., & Quindry, J.
- Affiliations
- Oakland University (US)
- St. Patrick Hospital (US)
- Corresponding author
- Franklin, Barry A.
- Venue
- Progress in Cardiovascular Diseases
- Publisher
- Elsevier BV
- Published
- 2022-01
- Volume
- 70
- Pages
- 22-32
- ISSN
- 0033-0620 (ISSN-L)
- OpenAlex
- W4200610393
- Cited by
- 18
- References
- 93
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 3 · 2023: 4 · 2022: 3
- FWCI
- 0.57
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Progress in Cardiovascular Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
- Keywords
- cardiac rehabilitation, high-intensity training, cardiorespiratory fitness, exercise capacity, cardiovascular disease, secondary prevention, marathon training, triathlon, endurance exercise, atrial fibrillation, coronary artery calcification, leisure-time physical activity, exercise safety, sedentary patients
- MeSH terms
- Cardiac Rehabilitation, Cardiorespiratory Fitness, Cardiovascular Diseases, Coronary Artery Disease, Exercise Therapy, Humans, Exercise
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