Psychological factors involved in psychopharmacological medication adherence in mental health patients: A systematic review
Abstract
Background Psychopharmacological medication adherence is essential for psychiatric patients' treatment and well-being.Objective This review aimed to identify psychological factors related to health control that have been linked to psychopharmacological medication adherence in psychiatric patients.Methods A literature search was performed through the databases Medline, PubMed, PsycINFO, and Google Scholar to identify relevant studies published before October 15th, 2019. Articles published in peer-reviewed journals that analyzed the psychological factors of health belief and health control involved in psychopharmacological medication adherence in a psychiatric population were included.Results The search identified 124 potentially relevant papers, 29 of which met the eligibility criteria. The final sample was 222 adolescents, most with a diagnosis of attention deficit/hyperactivity disorder (ADHD), and 6139 adults diagnosed especially with schizophrenia spectrum disorder, bipolar disorder, or depressive disorder. Results suggested that medication adherence is associated with health beliefs and psychological variables, such as self-efficacy and locus of control. Family support was also positively related to medication adherence.Conclusion Psychopharmacological medication adherence requires a consideration of multicausality, which depends on sociodemographic, clinical, and psychological factors.Practice implications These findings should be considered in the development and implementation of psychological interventions focused on self-control and family support.
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Adherence to psychopharmacological treatment is associated with patient characteristics (sociodemographic and clinical variables), health beliefs and psychological variables such as self-efficacy and locus of control.
“A systematic review has found that adherence to psychopharmacological treatment is associated with patient characteristics (sociodemographic and clinical variables), health beliefs and psychological variables, such as self-efficacy and locus of control [12].”
From Therapeutic Adherence of People with Mental Disorders: An Evolutionary Concept Analysis (2023) · cites this paper as [12]
Treatment complexity (polypharmacy) and illness chronicity are negatively associated with nonadherence to psychopharmacological treatment.
“Additionally, treatment complexity (polypharmacy) and illness chronicity have been identified as variables negatively associated with nonadherence to psychopharmacological treatment [12].”
From Therapeutic Adherence of People with Mental Disorders: An Evolutionary Concept Analysis (2023) · cites this paper as [12]
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- Authors
- Marrero, R. J., Fumero, A., de Miguel, A., & Peñate, W.
- Affiliations
- Universidad de La Laguna (ES)
- Corresponding author
- Marrero, Rosario J.
- Venue
- Patient Education and Counseling
- Publisher
- Elsevier BV
- Published
- 2020-10
- Volume
- 103
- Issue
- 10
- Pages
- 2116-2131
- ISSN
- 0738-3991 (ISSN-L)
- OpenAlex
- W3021384673
- Cited by
- 65
- References
- 77
- Citations by year
- 2026: 15 · 2025: 14 · 2024: 12 · 2023: 11 · 2022: 5 · 2021: 5 · 2020: 3
- FWCI
- 1.26
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Patient Education and Counseling (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- medication adherence, psychopharmacological treatment, psychiatric patients, psychological factors, health beliefs, self-efficacy, locus of control, family support, adolescents, attention deficit hyperactivity disorder, schizophrenia spectrum disorders, bipolar disorder, depressive disorders
- MeSH terms
- Adolescent, Adult, Attention Deficit Disorder with Hyperactivity, Mental Disorders, Bipolar Disorder, Humans, Mental Health, Schizophrenia, Medication Adherence
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