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Mechanism of Epigallocatechin-3-gallate in the prevention and treatment of irritable bowel syndrome: A network pharmacology and gene expression omnibus chip data-based study
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“Three Chinese herbal preparations that have been studied in clinical trials in IBS patients and demonstrated beneficial effects are the following:”
From Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines (2026) · cites this paper as [58]
In the citing paper
“Epigallocatechin-3-gallate (EGCG) (C22H18O11), the primary active component of green tea, may help prevent and treat IBS by targeting disease-related mechanisms identified through molecular docking analyses [58].”
From Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines (2026) · cites this paper as [58]
In the citing paper
“a double-blind placebo-controlled RCT with 80 IBS patients (1:1 40 per arm) showed beneficial effects of XSLJZT (chemical compound as above) (3 g three times per day for 28 days) in alleviating GI symptoms and improving quality of life in patients with IBS-D [58,59].”
From Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines (2026) · cites this paper as [58]
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Tea Polyphenols in Promotion of Human Health
Khan, N., & Mukhtar, H. (2018) · Nutrients · doi:10.3390/nu11010039 · Cited by 784
Irritable bowel syndrome: Pathogenesis, diagnosis, treatment, and evidence-based medicine
Saha, L. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i22.6759 · Cited by 500
Pace, F., Molteni, P., Bollani, S., Sarzi‐Puttini, P., Stockbrügger, R., Porro, G. B., & Drossman, D. A. (2003) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520310004524 · Cited by 157
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Post‐infectious IBS: Defining its clinical features and prognosis using an internet‐based survey
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Cited by
Pastras, P., Aggeletopoulou, I., Bali, M., & Triantos, C. (2026) · Nutrients · doi:10.3390/nu18020183 · Cited by 1
Metadata
- Authors
- Ye, F., Li, L., Wang, L., Ran, Y., Mei, L., Sun, Y., Zhang, X., & Dai, F.
- Venue
- PharmaNutrition
- Publisher
- Elsevier BV
- Published
- 2025-03
- Volume
- 31
- Pages
- 100433
- ISSN
- 2213-4344
- Cited by
- 3
- References
- 7
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Funders
- Shaanxi Province Key Research and Development Projects (S2023-YF-YBSF-1670)
- Northwestern University
- National Natural Science Foundation of China (81770540)
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