Cited by 784Tea Polyphenols and EffectsPhytochemicals and Antioxidant ActivitiesCoffee research and impacts

Tea Polyphenols in Promotion of Human Health

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Khan, Naghma, Mukhtar, Hasan·2018·Nutrients

Abstract

Tea is the most widely used beverage worldwide. Japanese and Chinese people have been drinking tea for centuries and in Asia, it is the most consumed beverage besides water. It is a rich source of pharmacologically active molecules which have been implicated to provide diverse health benefits. The three major forms of tea are green, black and oolong tea based on the degree of fermentation. The composition of tea differs with the species, season, leaves, climate, and horticultural practices. Polyphenols are the major active compounds present in teas. The catechins are the major polyphenolic compounds in green tea, which include epigallocatechin-3-gallate (EGCG), epigallocatechin, epicatechin-3-gallate and epicatechin, gallocatechins and gallocatechin gallate. EGCG is the predominant and most studied catechin in green tea. There are numerous evidences from cell culture and animal studies that tea polyphenols have beneficial effects against several pathological diseases including cancer, diabetes and cardiovascular diseases. The polyphenolic compounds present in black tea include theaflavins and thearubigins. In this review article, we will summarize recent studies documenting the role of tea polyphenols in the prevention of cancer, diabetes, cardiovascular and neurological diseases.

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  • Tea polyphenols have positive effect in prevention and treatment of muscle atrophy.

    “Tea polyphenols, mainly including epigallocatechin-3-gallate, epigallocatechin, epicatechin-3-gallate, epicatechin, gallocatechins, and gallocatechin gallate, have physiological activities such as antioxidant and anti-inflammation, and also have a positive effect in the prevention and treatment of muscle atrophy [103].”

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Authors
Khan, N., & Mukhtar, H.
Affiliations
University of Wisconsin–Madison (US)
Corresponding author
Khan, Naghma
Venue
Nutrients
Publisher
MDPI AG
Published
2018-12-25
Volume
11
Issue
1
Pages
39
ISSN
2072-6643 (ISSN-L)
OpenAlex
W2905663314
Cited by
784
References
68
Citations by year
2026: 90 · 2025: 113 · 2024: 118 · 2023: 119 · 2022: 145 · 2021: 89 · 2020: 84 · 2019: 22 · 2018: 1 · 2014: 2 · 2012: 1
FWCI
7.25
Type
journal article
Language
en
Open access
Locations
  • Nutrients (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • American Cancer Society (RSG-15-013-01-CNE)
  • University of Wisconsin Carbone Cancer Center (P30 CA014520)
Topics
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Tea Polyphenols and Effects
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Health Sciences › Medicine › Pharmacology › Coffee research and impacts
Keywords
tea polyphenols, catechins, epigallocatechin gallate, green tea, black tea, oolong tea, theaflavins, thearubigins, cancer prevention, diabetes mellitus, cardiovascular disease, neurological disorders, health benefits of tea
MeSH terms
Cardiovascular Diseases, Central Nervous System Diseases, Diabetes Mellitus, Humans, Neoplasms, Tea, Polyphenols

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