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The role of PPARα in lipid metabolism and obesity: Focusing on the effects of estrogen on PPARα actions
Abstract
Peroxisome proliferator-activated receptor alpha (PPARalpha) is a ligand-activated transcription factor that belongs to the steroid hormone receptor superfamily. PPARalpha is expressed predominantly in tissues that have a high level of fatty acid catabolism, such as liver, heart, and muscle. PPARalpha regulates the expression of a number of genes critical for lipid and lipoprotein metabolism. PPARalpha ligand fibrates have been used for the treatment of dyslipidemia due to their ability to lower plasma triglyceride levels and elevate HDL cholesterol levels. PPARalpha activators have been shown to regulate obesity in rodents by both increasing hepatic fatty acid oxidation and decreasing the levels of circulating triglycerides responsible for adipose cell hypertrophy and hyperplasia. However, these effects of PPARalpha on obesity and lipid metabolism may be exerted with sexual dimorphism and seem to be influenced by estrogen. Estrogen inhibits the actions of PPARalpha on obesity and lipid metabolism through its effects on PPARalpha-dependent regulation of target genes. Thus, the use of fibrates seems to be effective in men and postmenopausal women with obesity and lipid disorders, but not in premenopausal women with functioning ovaries.
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“For example, PPARα activates fatty acid oxidation by inducing lipid oxidation genes in mitochondria and peroxisomes (Yoon, 2009).”
From Mitochondrial response to nutrient availability and its role in metabolic disease (2014) · cites this paper as Yoon, 2009
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Cites
The Steroid and Thyroid Hormone Receptor Superfamily
Evans, R. M. (1988) · Science · doi:10.1126/science.3283939 · Cited by 7,394
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
Issemann, I., & Green, S. (1990) · Nature · doi:10.1038/347645a0 · Cited by 3,519
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism
Desvergne, B., & Wahli, W. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.5.0380 · Cited by 3,115
Braissant, O., Foufelle, F., Scotto, C., Dauça, M., & Wahli, W. (1996) · Endocrinology · doi:10.1210/endo.137.1.8536636 · Cited by 2,217
Kliewer, S. A., Sundseth, S. S., Jones, S. A., Brown, P. J., Wisely, G. B., Koble, C. S., Devchand, P., Wahli, W., Willson, T. M., Lenhard, J. M., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.9.4318 · Cited by 2,164
Forman, B. M., Chen, J., & Evans, R. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.9.4312 · Cited by 2,116
Roles of PPARs in health and disease
Kersten, S., Desvergne, B., & Wahli, W. (2000) · Nature · doi:10.1038/35013000 · Cited by 1,956
The PPARs: From Orphan Receptors to Drug Discovery
Willson, T. M., Brown, P. J., Sternbach, D. D., & Henke, B. R. (2000) · Journal of Medicinal Chemistry · doi:10.1021/jm990554g · Cited by 1,816
Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism
Staels, B., Dallongeville, J., Auwerx, J., Schoonjans, K., Leitersdorf, E., & Fruchart, J.-C. (1998) · Circulation · doi:10.1161/01.cir.98.19.2088 · Cited by 1,786
Lee, S. S. T., Pineau, T., Drago, J., Lee, E. J., Owens, J. W., Kroetz, D. L., Fernández‐Salguero, P. M., Westphal, H., & Gonzalez, F. J. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.6.3012 · Cited by 1,652
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Winkler, T. W., Justice, A. E., Graff, M., Barata, L., Feitosa, M. F., Chu, S. H., Czajkowski, J., Esko, T., Fall, T., Kilpeläinen, T. O., et al. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005378 · Cited by 681
Limonene: Aroma of innovation in health and disease
Vieira, A. J., Beserra, F. P., de Souza, M. C., Totti, B. M., & Rozza, A. L. (2018) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2018.02.007 · Cited by 388
Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity
Oka, T., Nishimura, Y., Zang, L., Hirano, M., Shimada, Y., Wang, Z., Umemoto, N., Kuroyanagi, J., Nishimura, N., & Tanaka, T. (2010) · BMC Physiology · doi:10.1186/1472-6793-10-21 · Cited by 386
Badmus, O. O., Hillhouse, S. A., Anderson, C. D., Hinds, T. D., & Stec, D. E. (2022) · Clinical Science · doi:10.1042/cs20220572 · Cited by 407
Phthalates: European regulation, chemistry, pharmacokinetic and related toxicity
Ventrice, P., Ventrice, D., Russo, E., & De Sarro, G. (2013) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2013.03.014 · Cited by 333
Harjumäki, R., Pridgeon, C. S., & Ingelman‐Sundberg, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158221 · Cited by 248
Tocmo, R., Peña-Fronteras, J. T., Calumba, K. F., Mendoza, M., & Johnson, J. J. (2020) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12561 · Cited by 225
Flavonoids as Antiobesity Agents: A Review
Rufino, A. T., Costa, V. M., Carvalho, F., & Fernandes, E. (2021) · Medicinal Research Reviews · doi:10.1002/med.21740 · Cited by 174
Lu, K., Xu, W., Wang, L., Zhang, D., Zhang, C., & Liu, W. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093135 · Cited by 175
Ji, H., Li, J., & Pin, L. (2011) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2011.01.009 · Cited by 167
The Role of PPAR α Activation in Liver and Muscle
Burri, L., Thoresen, G. H., & Berge, R. K. (2010) · PPAR Research · doi:10.1155/2010/542359 · Cited by 173
Lu, K., Xu, W., Li, X., Liu, W., Wang, L., & Zhang, C. (2013) · Aquaculture · doi:10.1016/j.aquaculture.2013.06.003 · Cited by 155
Mitochondrial response to nutrient availability and its role in metabolic disease
Gao, A. W., Cantó, C., & Houtkooper, R. H. (2014) · EMBO Molecular Medicine · doi:10.1002/emmm.201303782 · Cited by 148
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Tan, C. K., Leuenberger, N., Tan, M., Yan, Y. W., Chen, Y., Kambadur, R., Wahli, W., & Tan, N. S. (2011) · Diabetes · doi:10.2337/db10-0801 · Cited by 150
Li, J., Zhang, Y., Fan, S., Gu, M., Guan, Y., Lu, X., Huang, C., & Zhou, Z. (2013) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2013.06.022 · Cited by 151
Liu, Q., Pan, R., Ding, L., Zhang, F., Hu, L., Ding, B., Zhu, L., Xia, Y., & Dou, X. (2017) · International Immunopharmacology · doi:10.1016/j.intimp.2017.05.026 · Cited by 149
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Trivellin, G., & Korbonits, M. (2011) · Journal of Endocrinology · doi:10.1530/joe-11-0054 · Cited by 148
Zhou, W., Rahimnejad, S., Lu, K., Wang, L., & Liu, W. (2018) · Fish Physiology and Biochemistry · doi:10.1007/s10695-018-0536-7 · Cited by 141
Tao, C., Sifuentes, A. J., & Holland, W. L. (2013) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2013.11.003 · Cited by 139
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Boeckmans, J., Natale, A., Rombaut, M., Buyl, K., Rogiers, V., Kock, J. D., Vanhaecke, T., & Rodrigues, R. M. (2019) · Cells · doi:10.3390/cells9010037 · Cited by 126
Wu, C., Lin, M., Wang, H., Yang, M., Jou, M., & Wang, C. (2011) · Journal of Food Science · doi:10.1111/j.1750-3841.2010.02033.x · Cited by 129
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Delezie, J., & Challet, É. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06246.x · Cited by 124
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Chemello, F., Bean, C., Cancellara, P., Laveder, P., Reggiani, C., & Lanfranchi, G. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016807 · Cited by 114
AMPK-Dependent Metabolic Regulation by PPAR Agonists
Lee, W. H., & Kim, S. G. (2010) · PPAR Research · doi:10.1155/2010/549101 · Cited by 117
Kim, B., Farruggia, C., Ku, C. S., Pham, T. X., Yang, Y. J., Bae, M., Wegner, C., Farrell, N., Harness, E., Park, Y., et al. (2016) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2016.01.006 · Cited by 112
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Shankar, K., Kang, P., Harrell, A., Zhong, Y., Marecki, J. C., Ronis, M. J. J., & Badger, T. M. (2010) · Endocrinology · doi:10.1210/en.2010-0017 · Cited by 107
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Hijona, E., Hijona, L., Arenas, J. I., & Bujanda, L. (2010) · Mediators of Inflammation · doi:10.1155/2010/837419 · Cited by 105
The Role of PPAR and Its Cross-Talk with CAR and LXR in Obesity and Atherosclerosis
Xu, P., Zhai, Y., & Wang, J. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19041260 · Cited by 114
Higuchi, N., Kato, M., Tanaka, M., MIYAZAKI, M., TAKAO, S., Kohjima, M., Kotoh, K., Enjoji, M., Nakamuta, M., & Takayanagi, R. (2011) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2011.328 · Cited by 111
Hu, W., Fitzgerald, M. A., Topp, B. L., Alam, M. M., & O’Hare, T. J. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103520 · Cited by 107
Ding, Q., Cao, F., Lai, S., Zhuge, H., Chang, K., Valencak, T. G., Liu, J., Li, S., & Ren, D. (2022) · Food Research International · doi:10.1016/j.foodres.2022.111259 · Cited by 101
Youssef, D. A., El‐Fayoumi, H. M., & Mahmoud, M. F. (2018) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2018.10.010 · Cited by 97
Montrose, L. B., Padmanabhan, V., Goodrich, J. M., Domino, S. E., Treadwell, M. C., Meeker, J. D., Watkins, D. J., & Dolinoy, D. C. (2018) · Epigenetics · doi:10.1080/15592294.2018.1448680 · Cited by 92
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Rando, G., & Wahli, W. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2010.12.023 · Cited by 91
Berardo, C., Pasqua, L. G. D., Cagna, M., Richelmi, P., Vairetti, M., & Ferrigno, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21249646 · Cited by 89
Takayanagi, K., Morimoto, S.-I., Shirakura, Y., Mukai, K., Sugiyama, T., Tokuji, Y., & Ohnishi, M. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf202821u · Cited by 79
Wang, W., Zhang, X., Wang, Z., Qin, J., Wang, W., Tian, H., & Ru, S. (2018) · Chemosphere · doi:10.1016/j.chemosphere.2018.01.163 · Cited by 78
Huang, Q., Ma, C., Chen, L., Luo, D., Chen, R., & Liang, F. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00370 · Cited by 78
Han, S., Jiao, J., Zhang, W., Xu, J., Wan, Z., Zhang, W., Gao, X., & Qin, L. (2015) · Scientific Reports · doi:10.1038/srep15256 · Cited by 77
Linher‐Melville, K., Zantinge, S., Sanli, T., Gerstein, H. C., Tsakiridis, T. K., & Singh, G. (2011) · BMC Cancer · doi:10.1186/1471-2407-11-56 · Cited by 75
Hinds, T. D., Kipp, Z. A., Xu, M., Yiannikouris, F. B., Morris, A. J., Stec, D. F., Wahli, W., & Stec, D. E. (2021) · Cells · doi:10.3390/cells11010004 · Cited by 72
PPAR α in Obesity: Sex Difference and Estrogen Involvement
Yoon, M. (2010) · PPAR Research · doi:10.1155/2010/584296 · Cited by 74
Self-citationLiu, X., Cui, J., Li, Z., Xu, J., Wang, J., Xue, C., & Wang, Y. (2013) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201300407 · Cited by 70
Insight into molecular pathways of retinal metabolism, associated with vitellogenesis in zebrafish
Levi, L., Ziv, T., Admon, A., Levavi‐Sivan, B., & Lubzens, E. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00310.2011 · Cited by 70
Lee, H., Ahn, J., Shin, S. S., & Yoon, M. (2018) · International Journal of Obesity · doi:10.1038/s41366-018-0212-0 · Cited by 69
Self-citationWang, C., Guo, Y., Zhou, M., Xue, C., Chang, Y., Zhang, T., & Wang, Y. (2019) · Food & Function · doi:10.1039/c8fo01822g · Cited by 69
Stearoyl-CoA Desaturase: A Vital Checkpoint in the Development and Progression of Obesity
Poudyal, H., & Brown, L. (2011) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/187153011796429826 · Cited by 67
Direct effects of iodothyronines on excess fat storage in rat hepatocytes
Grasselli, E., Voci, A., Canesi, L., Matteis, R. D., Goglia, F., Cioffi, F., Fugassa, E., Gallo, G., & Vergani, L. (2010) · Journal of Hepatology · doi:10.1016/j.jhep.2010.09.027 · Cited by 64
Template to improve glycemic control without reducing adiposity or dietary fat
Krishnapuram, R., Dhurandhar, E. J., Dubuisson, O. S., Kirk-Ballard, H., Bajpeyi, S., Butte, N. F., SOTHERN, M. S., Larsen-Meyer, E., Chalew, S. A., Bennett, B., et al. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00703.2010 · Cited by 65
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Zhang, Y., Li, B., Cananzi, S. G., Han, C., Wang, L., Zou, Y., Fu, Y., Hon, G. C., & Zhang, C. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2107339119 · Cited by 65
Ji, R., Xiang, X., Li, X., Mai, K., & Ai, Q. (2020) · British Journal Of Nutrition · doi:10.1017/s0007114520004171 · Cited by 62
Tian, J., Lu, R., Ji, H., Sun, J. H., Li, C., Pin, L., Lei, C., Chen, L., & Du, Z. (2015) · Gene · doi:10.1016/j.gene.2015.04.010 · Cited by 62
Khoo, N. K. H., Hebbar, S., Zhao, W., Moore, S. A., Domann, F. E., & Robbins, M. E. C. (2013) · Redox Biology · doi:10.1016/j.redox.2012.12.006 · Cited by 65
Wang, W., Zhang, X., Qin, J., Wei, P., Jia, Y., Wang, J., & Ru, S. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.01.020 · Cited by 62
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Yeh, Y., Cho, Y.-Y., Hsieh, S., & Chiang, A. (2018) · Scientific Reports · doi:10.1038/s41598-018-19553-1 · Cited by 59
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Kang, H. S., Cho, H., Lee, J., Oh, G. T., Koo, S., Park, B., Lee, I., Choi, H., Song, D., & Im, S. (2016) · Scientific Reports · doi:10.1038/srep23665 · Cited by 59
Cao, X., Liu, W., Zheng, X., Yuan, X., Wang, C., & Jiang, G. (2018) · Aquaculture Nutrition · doi:10.1111/anu.12834 · Cited by 54
Yang, X., Wang, Q., Pang, Z.-R., Pan, M.-R., & Zhang, W. (2017) · Pharmaceutical Biology · doi:10.1080/13880209.2016.1278454 · Cited by 53
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Long, X., Zeng, X., Tan, F., Yi, R., Pan, Y., Zhou, X., Mu, J., & Zhao, X. (2020) · Food & Function · doi:10.1039/d0fo00519c · Cited by 50
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Rebollo, A., Roglans, N., Baena, M., Sánchez, R. M., Merlos, M., Alegret, M., & Laguna, J. C. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2014.01.002 · Cited by 51
Beattie, J. H., Nicol, F., Gordon, M., Reid, M., Cantlay, L. L., Horgan, G. W., Kwun, I., Ahn, J., & Ha, T. Y. (2011) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201100193 · Cited by 48
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Ramdas, S., Judd, J., Graham, S. E., Kanoni, S., Wang, Y., Surakka, I. L., Wenz, B. M., Clarke, S. L., Chesi, A., Wells, A. D., et al. (2022) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2022.06.012 · Cited by 48
Tan, S., Li, M., Ding, X., Fan, S., Guo, L., Gu, M., Zhang, Y., Li, F., Jiang, D., Li, Y., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093510 · Cited by 47
AlSaleh, A. F. F., Sanders, T. A. B., & O’Dell, S. D. (2011) · Proceedings of The Nutrition Society · doi:10.1017/s0029665111003181 · Cited by 47
Lago-Fernandez, A., Zarzo-Arias, S., Jagerovic, N., & Morales, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031001 · Cited by 50
Maki, T., Maeda, Y., Sonoda, N., Makimura, H., Kimura, S., Maeno, S., Takayanagi, R., & Inoguchi, T. (2017) · Metabolism · doi:10.1016/j.metabol.2017.02.013 · Cited by 44
Wang, X., Huang, M. H., & Wang, Y. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048069 · Cited by 45
Yin, F., Yu, H., Lepp, D., Shi, X., Yang, X., Hu, J., Leeson, S., Yang, C., Nie, S., Hou, Y., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0160751 · Cited by 46
Ispada, J., de Lima, C. B., Sirard, M., Fontes, P. K., Nogueira, M. F. G., Annes, K., & Milazzotto, M. P. (2018) · Epigenetics & Chromatin · doi:10.1186/s13072-017-0171-z · Cited by 48
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Kim, J., Lee, H., Lim, J., Oh, J.-H., Shin, S. C., & Yoon, M. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18040846 · Cited by 41
Self-citationRetractedLee, H., Kim, M. K., Shin, S. S., & Yoon, M. (2014) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2014.07.034 · Cited by 40
Self-citationGou, N., Chang, Z., Deng, W. W., Ji, H., & Zhou, J. (2019) · Aquaculture Research · doi:10.1111/are.14295 · Cited by 40
Role of AMPK and PPARγ1 in exercise-induced lipoprotein lipase in skeletal muscle
Sasaki, T., Nakata, R., Inoue, H., Shimizu, M., Inoue, J., & Sato, R. (2014) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00691.2013 · Cited by 39
D-Limonene mitigate myocardial injury in rats through MAPK/ERK/NF-κB pathway inhibition
Younis, N. S. (2020) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2020.24.3.259 · Cited by 38
Pezeshki, H., Rajabi, S., Hashemi, M., Moradalizadeh, S., & Nasab, H. (2025) · Heliyon · doi:10.1016/j.heliyon.2025.e42782 · Cited by 39
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Park, B. Y., Lee, H., Woo, S., Yoon, M.-S., Kim, J., Hong, Y., Lee, H. S., Park, E. K., Hahm, J. C., Kim, J. W., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0141612 · Cited by 39
Self-citationYang, Y., Du, L., Hosokawa, M., & Miyashita, K. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103741 · Cited by 38
Ding, F., Ma, B., Nazary-Vannani, A., Kord‐Varkaneh, H., Fatahi, S., Papageorgiou, M., Rahmani, J., Poursoleiman, F., do Nascimento, I. J. B., Li, H., et al. (2019) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2019.10.002 · Cited by 37
Moraes, J. G. N., Behura, S. K., Geary, T. W., & Spencer, T. E. (2019) · Biology of Reproduction · doi:10.1093/biolre/ioz191 · Cited by 37
Zappaterra, M., Gioiosa, S., Chillemi, G., Zambonelli, P., & Davoli, R. (2020) · PLoS ONE · doi:10.1371/journal.pone.0233372 · Cited by 38
Martínez, N., Kurtz, M., Capobianco, E., Higa, R., White, V., & Jawerbaum, A. (2011) · Journal of Molecular Endocrinology · doi:10.1530/jme-10-0173 · Cited by 37
Benefits of Polyphenols and Methylxanthines from Cocoa Beans on Dietary Metabolic Disorders
Jean-Marie, É., Béreau, D., & Robinson, J.-C. (2021) · Foods · doi:10.3390/foods10092049 · Cited by 44
Wang, J., He, W., Yang, D., Cao, H., Bai, Y., Guo, J., & Su, Z. (2019) · Molecules · doi:10.3390/molecules24244455 · Cited by 36
Metadata
- Authors
- Yoon, M.
- Affiliations
- Mokwon University (KR)
- Corresponding author
- Yoon, Michung
- ORCID
- Yoon, Michung
- Venue
- Pharmacological Research
- Publisher
- Elsevier BV
- Published
- 2009-09
- Volume
- 60
- Issue
- 3
- Pages
- 151-159
- ISSN
- 1043-6618 (ISSN-L)
- OpenAlex
- W2026756943
- Cited by
- 336
- References
- 155
- Citations by year
- 2026: 12 · 2025: 25 · 2024: 13 · 2023: 23 · 2022: 33 · 2021: 20 · 2020: 27 · 2019: 27 · 2018: 25 · 2017: 15 · 2016: 16 · 2015: 15 · 2014: 18 · 2013: 14 · 2012: 17
- FWCI
- 7.11
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pharmacological Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Peroxisome Proliferator-Activated Receptors
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Paraoxonase enzyme and polymorphisms
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Keywords
- PPARα, estrogen, obesity, lipid metabolism, fibrates, dyslipidemia, hepatic fatty acid oxidation, triglycerides, HDL cholesterol, sexual dimorphism, postmenopausal women, premenopausal women, lipoprotein metabolism
- MeSH terms
- Animals, Estrogens, Female, Humans, Male, Obesity, PPAR alpha, Lipid Metabolism
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