The DOI matches its Crossref record; 75 of the 75 references it cites were found in a registry or an index.
Anti-diabetic drugs and weight loss in patients with type 2 diabetes
Open accessAbstract
Introduction Obesity is frequently a comorbidity of type 2 diabetes. Even modest weight loss can significantly improve glucose homeostasis and lessen cardiometabolic risk factors in patients with type 2 diabetes, but lifestyle-based weight loss strategies are not long-term effective. There is an increasing need to consider pharmacological approaches to assist weight loss in the so called diabesity syndrome. Aim of this review is to analyze the weight-loss effect of non-insulin glucose lowering drugs in patients with type 2 diabetes.Material and methods A systematic analysis of the literature on the effect of non-insulin glucose lowering drugs on weight loss in patients with type 2 diabetes was performed. For each class of drugs, the following parameters were analyzed: kilograms lost on average, effect on body mass index and body composition.Results Our results suggested that anti-diabetic drugs can be stratified into 3 groups based on their efficacy in weight loss: metformin, acarbose, empagliflozin and exenatide resulted in a in a mild weight loss (less than 3.2% of initial weight); canagliflozin, ertugliflozin, dapagliflozin and dulaglutide induces a moderate weight loss (between 3.2% and 5%); liraglutide, semaglutide and tirzepatide resulted in a strong weight loss (greater than 5%).Conclusions This study shows that new anti-diabetic drugs, particularly GLP1-RA and Tirzepatide, are the most effective in inducing weight loss in patients with type 2 diabetes. Interestingly, exenatide appears to be the only GLP1-RA that induces a mild weight loss.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In a recent study by Lazzaroni et al., 61 they documented a higher (>5%) reduction in weight among T2D patients who were given liraglutide, semaglutide, and tirzepatide.”
From Anti-inflammatory role of glucagon-like peptide 1 receptor agonists and its clinical implications (2024) · cites this paper as [61]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“GLP-1 receptor agonists have been demonstrated to have significant benefits in weight reduction and can also lower the risk of major cardiovascular events, all-cause mortality, hospital admission for heart failure, and worsening kidney function.4,5”
From Tirzepatide: Clinical review of the twincretin injectable (2023) · cites this paper as [5]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
Metformin monotherapy for type 2 diabetes mellitus
Sáenz, A., Fernandez-Esteban, I., Mataix, A. L., Segura, M. A., Figuls, M. R. I., & Moher, D. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002966.pub3 · Cited by 310
RetractedCanagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
Neal, B., Perkovic, V., Mahaffey, K. W., de Zeeuw, D., Fulcher, G., Erondu, N., Shaw, W., Law, G., Desai, M., & Matthews, D. R. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1611925 · Cited by 7,830
10-year follow-up of intensive glucose control in type 2 diabetes
Holman, R. R., Paul, S. K., Bethel, M. A., Matthews, D. R., & Neil, H. A. W. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0806470 · Cited by 7,751
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
Marso, S. P., Bain, S. C., Consoli, A., Eliaschewitz, F. G., Jódar, E., Leiter, L. A., Lingvay, I., Rosenstock, J., Seufert, J., Warren, M. L., et al. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1607141 · Cited by 6,900 · cited 1×
“9kg in absolute value) with semaglutide 1 mg [67].”
BackgroundDapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes
Wiviott, S. D., Raz, I., Bonaca, M. P., Mosenzon, O., Kato, E. T., Cahn, A., Silverman, M. G., Zelniker, T. A., Kuder, J. F., Murphy, S. A., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1812389 · Cited by 6,382
Global and societal implications of the diabetes epidemic
Zimmet, P., Alberti, K. G. M. M., & Shaw, J. (2001) · Nature · doi:10.1038/414782a · Cited by 5,883
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
Kahn, S. E., Haffner, S. M., Heise, M. A., Herman, W. H., Holman, R. R., Jones, N. P., Kravitz, B. G., Lachin, J. M., O'Neill, M. C., Zinman, B., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa066224 · Cited by 2,962
Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes
Husain, M., Birkenfeld, A. L., Donsmark, M., Dungan, K., Eliaschewitz, F. G., Franco, D. R., Jeppesen, O. K., Lingvay, I., Mosenzon, O., Pedersen, S. D., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1901118 · Cited by 1,997
Wing, R. R., Lang, W., Wadden, T. A., Safford, M., Knowler, W. C., Bertoni, A. G., Hill, J. O., Brancati, F. L., Peters, A., Wagenknecht, L., et al. (2011) · Diabetes Care · doi:10.2337/dc10-2415 · Cited by 1,828
DeFronzo, R. A., Ratner, R. E., Han, J., Kim, D. D., Fineman, M. S., & Baron, A. D. (2005) · Diabetes Care · doi:10.2337/diacare.28.5.1092 · Cited by 1,559
Cited by
Sorted by citations
Anti-inflammatory role of glucagon-like peptide 1 receptor agonists and its clinical implications
Alharbi, S. H. (2024) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/20420188231222367 · Cited by 358
Pharmaceutical Drugs and Natural Therapeutic Products for the Treatment of Type 2 Diabetes Mellitus
Bláhová, J., Martiniaková, M., Babikova, M., Kováčová, V., Mondočková, V., & Omelka, R. (2021) · Pharmaceuticals · doi:10.3390/ph14080806 · Cited by 333
Stefanakis, K., Kokkorakis, M., & Mantzoros, C. S. (2024) · Metabolism · doi:10.1016/j.metabol.2024.156057 · Cited by 142
GLP-1 receptor agonist as a modulator of innate immunity
Chen, J., Mei, A., Wei, Y., Li, C., Qian, H., Min, X., Yang, H., Dong, L., Rao, X., & Zhong, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.997578 · Cited by 120
Tirzepatide: A Systematic Update
Forzano, I., Varzideh, F., Avvisato, R., Jankauskas, S. S., Mone, P., & Santulli, G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232314631 · Cited by 118
Sarcopenia and Diabetes: A Detrimental Liaison of Advancing Age
Lisco, G., Disoteo, O., Tullio, A. D., Geronimo, V. D., Giagulli, V. A., Monzani, F., Jirillo, E., Cozzi, R. C., Guastamacchia, E., Pergola, G. D., et al. (2023) · Nutrients · doi:10.3390/nu16010063 · Cited by 111
Management of diabesity: Current concepts
Michaelidou, M., Pappachan, J. M., & Jeeyavudeen, M. S. (2023) · World Journal of Diabetes · doi:10.4239/wjd.v14.i4.396 · Cited by 97
SGLT2-inhibitors are effective and safe in the elderly: the SOLD study
Lunati, M. E., Cimino, V., Gandolfi, A., Trevisan, M., Montefusco, L., Pastore, I., Pace, C., Betella, N., Favacchio, G., Bulgheroni, M., et al. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106396 · Cited by 77
Self-citationVolpe, S., Lisco, G., Racaniello, D., Fanelli, M., Colaianni, V., Vozza, A., Triggiani, V., Sabbà, C., Tortorella, C., De Pergola, G., et al. (2022) · Nutrients · doi:10.3390/nu14122414 · Cited by 67
Su, L., Xin, C., Yang, J., Dong, L., Mei, H., Dai, X., & Wang, Q. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.06.071 · Cited by 67
A Comprehensive Review on Weight Loss Associated with Anti-Diabetic Medications
Haddad, F., Dokmak, G., Bader, M., & Karaman, R. (2023) · Life · doi:10.3390/life13041012 · Cited by 71
Khodayari, P., & Ebrahimzadeh, H. (2023) · Analytica Chimica Acta · doi:10.1016/j.aca.2023.341765 · Cited by 59
Domingo, E., Marqués, P., Francisco, V., Piqueras, L., & Sanz, M. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107058 · Cited by 63
Güney, C., Bal, N. B., & Akar, F. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e18896 · Cited by 53
Cai, W., Zhang, R., Yao, Y., Wu, Q., & Zhang, J. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1277113 · Cited by 54
Cost-effectiveness analysis of 4 GLP-1RAs in the treatment of obesity in a US setting
Hu, Y., Zheng, S.-L., Ye, X.-L., Shi, J.-N., Zheng, X.-W., Pan, H.-S., Zhang, Y.-W., Yang, X.-L., & Huang, P. (2022) · Annals of Translational Medicine · doi:10.21037/atm-22-200 · Cited by 45
Hankosky, E. R., Wang, H., Neff, L. M., Kan, H., Wang, F., Ahmad, N. N., Stefanski, A., & Garvey, W. T. (2023) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.15269 · Cited by 44
Sulforaphane: A nutraceutical against diabetes-related complications
Mthembu, S. X. H., Mazibuko-Mbeje, S. E., Moetlediwa, M. T., Muvhulawa, N., Silvestri, S., Orlando, P., Nkambule, B. B., Muller, C. J. F., Ndwandwe, D. E., Basson, A. K., et al. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106918 · Cited by 37
Nassar, M., Nassar, O., Abosheaishaa, H. M., & Misra, A. (2024) · Journal of Endocrinological Investigation · doi:10.1007/s40618-024-02466-4 · Cited by 34
Silverii, G. A. (2024) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.15749 · Cited by 33
Mechanisms of action of incretin receptor based dual- and tri-agonists in pancreatic islets
Folli, F. B., Finzi, G., Manfrini, R., Galli, A., Casiraghi, F., Centofanti, L., Berra, C., Fiorina, P., Davalli, A. M., Rosa, S. L., et al. (2023) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00236.2023 · Cited by 32
Self-citationMuscle loss and GLP-1R agonists use
Rossi, G., Bucciarelli, L., Mananguite, C.-L., Giovarelli, M., & Fiorina, P. (2025) · Acta Diabetologica · doi:10.1007/s00592-025-02611-2 · Cited by 31
“Their multifaceted benefits, including significant improvements in glycemic control and weight reduction, together with cardiovascular and renal protection, have led to their widespread use across various clinical settings [8– 10].”
Self-citationType 2 diabetes mellitus pharmacological remission with dapagliflozin plus oral semaglutide
Lunati, M. E., Cimino, V., Bernasconi, D. P., Gandolfi, A., Morpurgo, P. S., Tinari, C., Lazzaroni, E., Baruffaldi, L., Muratori, M., Montefusco, L. B., et al. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.107040 · Cited by 31
Self-citationMetformin: From diabetes to cancer to prolongation of life
Sirtori, C. R., Castiglione, S., & Pavanello, C. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107367 · Cited by 38
Unlocking the multifaceted roles of GLP-1: Physiological functions and therapeutic potential
AL-Noshokaty, T. M., Abdelhamid, R., Abdelmaksoud, N. M., Khaled, A., Hossam, M., Ahmed, R., Saber, T., Khaled, S., Elshaer, S. S., & Abulsoud, A. I. (2025) · Toxicology Reports · doi:10.1016/j.toxrep.2025.101895 · Cited by 30
Chovsepian, A., Prokopchuk, O., Petrova, G., Gjini, T., Kuzi, H., Heisz, S., Janssen, K., Martignoni, M. E., Friess, H., Hauner, H., et al. (2023) · Molecular Metabolism · doi:10.1016/j.molmet.2023.101729 · Cited by 30
Giannakogeorgou, A., & Roden, M. (2024) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.17848 · Cited by 30
Berra, C. C., Rossi, M. C., Mirani, M., Ceccarelli Ceccarelli, D., Romano, C., Sassi, L., Peretti, E., Favacchio, G., Pastore, I., Folini, L., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.1099451 · Cited by 28
Self-citationTirzepatida: Un Avance Revolucionario en el Tratamiento de la Diabetes Mellitus Tipo 2 y la Obesidad
Chávez, M. (2023) · Revista Veritas de Difusão Cientifica. · doi:10.61616/rvdc.v4i1.39 · Cited by 28
Cencioni, C., Malatesta, S., Benedetti, V. V., Licursi, V., Perfetto, L., Conte, F., Ranieri, D., Bartolazzi, A., Kunkl, M., Tuosto, L., et al. (2025) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-024-03263-w · Cited by 31
Wang, Y., Deng, F., Zhong, X., Du, Y., Fan, X., Su, H., & Pan, T. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.175730 · Cited by 30
Marassi, M., Cignarella, A., Russo, G. T., Nollino, L., Strazzabosco, M., Marzullo, P., Leonetti, F., Avogaro, A., Consoli, A., & Fadini, G. P. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107866 · Cited by 33
Al-Mhanna, S. B., Franklin, B. A., Tarnopolsky, M. A., Hawley, J. A., Jakicic, J. M., Stamatakis, E., Little, J. P., Pescatello, L. S., Riebe, D. A., Thompson, W. R., et al. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-025-01974-4 · Cited by 29
Medical treatment of weight loss in children and adolescents with obesity
Calcaterra, V., Rossi, V., Mari, A., Casini, F., Bergamaschi, F., Zuccotti, G., & Fabiano, V. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106471 · Cited by 25
Self-citationWu, T., Feng, H., He, M., Yue, R., & Wu, S. (2021) · Pharmacological Research · doi:10.1016/j.phrs.2021.105994 · Cited by 22
Sun, L., Yuan, Y., Li, Y., & Rao, X. (2023) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2023.11948 · Cited by 20
Shahinfar, H., Jayedi, A., Torabynasab, K., Payandeh, N., Martami, F., Moosavi, H., Bazshahi, E., & Shab‐Bidar, S. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106944 · Cited by 22
Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity
Ramms, B., Pollow, D. P., Zhu, H., Nora, C., Harrington, A. R., Omar, I., Gordts, P. L. S. M., Wortham, M., & Sander, M. (2022) · Diabetes · doi:10.2337/db21-1131 · Cited by 21
Branković, M., Dukić, M., Gmizić, T., Popadić, V., Nikolić, N., Sekulic, A. D., Brajković, M., Đokić, J., Mahmutović, E., Lasica, R., et al. (2024) · Diagnostics · doi:10.3390/diagnostics14020229 · Cited by 21
Therapeutic strategies targeting mechanisms of macrophages in diabetic heart disease
Zhang, C., Shi, Y., Liu, C., Sudesh, S. M., Zhao, H., Li, P., Liu, Q., Ma, Y., Shi, A., & Cai, H. (2024) · Cardiovascular Diabetology · doi:10.1186/s12933-024-02273-4 · Cited by 24
Gitto, M., Catapano, F., Francone, M., Mincione, G., Scialò, V., Pivato, C. A., Lisi, C., Regazzoli, D., Cao, D., Fiorina, R. M., et al. (2025) · Acta Diabetologica · doi:10.1007/s00592-025-02606-z · Cited by 21
Self-citationRevisiting the concept of incretin and enteroendocrine L-cells as type 2 diabetes mellitus treatment
Lok, K.-H., Wareham, N. J., Nair, R. S., How, C. W., & Chuah, L. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106237 · Cited by 19
An updated patent review of GLP-1 receptor agonists (2020-present)
Lu, W., Zhou, Z., Jiang, N., & Han, J. (2023) · Expert Opinion on Therapeutic Patents · doi:10.1080/13543776.2023.2274905 · Cited by 17
Mahar, M. U., Mahmud, O., Ahmed, S., Qureshi, S. A., Kakar, W. G., & Fatima, S. S. (2024) · Journal of Obesity & Metabolic Syndrome · doi:10.7570/jomes24008 · Cited by 24
Dapagliflozin acutely improves kidney function in type 2 diabetes mellitus. The PRECARE study
Lazzaroni, E., Lunati, M. E., Montefusco, L. B., Pastore, I., Chebat, E., Cimino, V., Morpurgo, P. S., Muratori, M., Plebani, L., Bolla, A. M., et al. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106374 · Cited by 17
Self-citationYu, Y., Hu, G., Yin, S., Yang, X., Zhou, M., & Jian, W. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.990182 · Cited by 18
Berra, C., Manfrini, R., Bifari, F., Cipponeri, E., Ghelardi, R., Centofanti, L., Mortola, U., Lunati, E., Bucciarelli, L. G., Cimino, V., et al. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107517 · Cited by 19
Self-citationCherney, D. Z. I., Bell, A., Girard, L., McFarlane, P. A., MOIST, L. M., Nessim, S. J., Soroka, S. D., Stafford, S. G., Steele, A., Tangri, N., et al. (2023) · Canadian Journal of Kidney Health and Disease · doi:10.1177/20543581221150556 · Cited by 18
Xie, J., Xie, P., Guo, M. L., Li, F., Xiao, M., Qi, Y.-S., Pei, W., Luo, H.-T., Gu, Y., & Piao, X. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1215150 · Cited by 16
Yu, J., Da, J., Yu, F., Yuan, J., & Zha, Y. (2024) · Journal of Endocrinological Investigation · doi:10.1007/s40618-023-02292-0 · Cited by 20
Botticelli, L., Bonaventura, E. M. D., Bello, F. D., Giorgioni, G., Piergentili, A., Quaglia, W., Bonifazi, A., Cifani, C., & Bonaventura, M. V. M. D. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106875 · Cited by 16
Stratification of obesity phenotypes to optimize future therapy (SOPHIA)
Tahrani, A. A., Panova‐Noeva, M., Schloot, N. C., Hennige, A. M., Söderberg, J. A. E., Nadglowski, J. F., Tarasenko, L. C., Ahmad, N. N., Sleypen, B. S., Bravo, R., et al. (2023) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2023.2264783 · Cited by 15
Diabetes mellitus: interdisciplinary medical, surgical and psychological therapeutic approach
Socea, B., Silaghi, A. M., Rebegea, L. F., Bălan, D. G., Bălălău, C., Ţenea-Cojan, T. Ş., Mihai, D. A., & Păunică, I. (2023) · Journal of Mind and Medical Sciences · doi:10.22543/2392-7674.1445 · Cited by 16
Suzuki, Y., Kaneko, H., Okada, A., Ohno, R., Yokota, I., Fujiu, K., Jo, T., Takeda, N., Morita, H., Node, K., et al. (2023) · Journal of Endocrinological Investigation · doi:10.1007/s40618-023-02246-6 · Cited by 15
Sinha, A., Puri, P., & Pati, S. (2022) · BMJ Open · doi:10.1136/bmjopen-2022-061154 · Cited by 14
AWARE A novel web application to rapidly assess cardiovascular risk in type 2 diabetes mellitus
Berra, C., Manfrini, R., Mirani, M., Bucciarelli, L., Zakaria, A., Piccini, S., Ghelardi, R., Lunati, M. E., Rodovalho, S., Bifari, F., et al. (2023) · Acta Diabetologica · doi:10.1007/s00592-023-02115-x · Cited by 13
Self-citationJabeen, K., Rehman, K., Akash, M. S. H., Nadeem, A., & Mir, T. M. (2023) · Biomedicines · doi:10.3390/biomedicines11092453 · Cited by 14
Li, Y., Gong, X., Găman, M., Hernández‐Wolters, B., Velu, P., & Li, Y. (2023) · European Journal of Clinical Investigation · doi:10.1111/eci.14125 · Cited by 16
Olofinsan, K. A., Salau, V. F., Erukainure, O. L., & Islam, M. S. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115998 · Cited by 14
Kobayashi, K., Toyoda, M., Hatori, N., Sakai, H., Furuki, T., Chin, K., Kimura, M., Saito, N., Kanaoka, T., Aoyama, T., et al. (2022) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2022.109231 · Cited by 15
Brahma, S., Goyal, A. K., Prakash, D., Kumari, M. R., Sadasivam, J., Usha, T., & Middha, S. K. (2023) · Current Diabetes Reviews · doi:10.2174/1573399819666230314093721 · Cited by 13
Tirzepatide: Clinical review of the twincretin injectable
Krauss, Z., Hintz, A., & Fisk, R. (2023) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/zxad080 · Cited by 12
Psychotropic effects of GLP-1R agonists
Bucciarelli, L. G., Cimino, V., Dell’Osso, B. M., & Fiorina, P. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.108036 · Cited by 13
Self-citationAbutaima, R., Barakat, M. M., Sawan, H. M., Omari, S. M. A., & Mhaidat, N. M. (2024) · PLoS ONE · doi:10.1371/journal.pone.0314407 · Cited by 12
Effect of empagliflozin on weight in patients with prediabetes and diabetes
Sanjari, M., Hadavizadeh, M., Sadeghi, N., & Naghibzadeh‐Tahami, A. (2025) · Scientific Reports · doi:10.1038/s41598-024-83820-7 · Cited by 14
Ciccarelli, G., Giuseppe, G. D., Cinti, F., Moffa, S., Mezza, T., & Giaccari, A. (2023) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3668 · Cited by 11
Lin, B., Guo, X., Lü, W., Niu, R. L., Zeng, X., Chen, Z., Wu, C., & Liu, C. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176742 · Cited by 10
Morus alba: natural and valuable effects in weight loss management
Ntalouka, F., & Tsirivakou, A. (2024) · Frontiers in Clinical Diabetes and Healthcare · doi:10.3389/fcdhc.2024.1395688 · Cited by 10
Chen, B., Tao, L., Tian, M., & Ji, Z. (2025) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2025.01.056 · Cited by 10
Gamal, N., Bakly, W. M. S. E., Saad, S. S. T., El-Waseef, D. A. E.-D. A., El‐Shal, A. S., Morsy, W. E., & Magdy, Y. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04136-5 · Cited by 10
Liang, W., & Sun, F. (2023) · Journal of Endocrinological Investigation · doi:10.1007/s40618-023-02233-x · Cited by 12
Comparison of the Impact of SGLT2-Inhibitors and Exenatide on Body Fat Composition
Agcakaya, E., Mutlu, H. H., Erbakan, A. N., & Sargın, M. (2023) · Journal of College of Physicians And Surgeons Pakistan · doi:10.29271/jcpsp.2023.03.308 · Cited by 9
Ogunsanmi, D., Harrison, A., Pakker, A. R., Kovesdy, C. P., Bailey, J. E., & Surbhi, S. (2023) · Journal of Managed Care & Specialty Pharmacy · doi:10.18553/jmcp.2023.29.6.699 · Cited by 9
Responsible Use of Oral Corticosteroids in People with Comorbid Diabetes: An Expert Consensus
Saboo, B., Joshi, S., Gupta, A. S., Maheshwari, A., Saboo, B., Makkar, B. M., Bantwal, G., Kesavadev, J., Murthy, L. S., TIWASKAR, M. H., et al. (2024) · Journal of the Association of Physicians of India · doi:10.59556/japi.72.0573 · Cited by 9
Kalita, P., Pathak, M. P., Barbhuiya, P. A., & Nongkhlaw, F. T. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.144856 · Cited by 8
A New Strategy for Obesity Treatment: Revealing the Frontiers of Anti-obesity Medications
Huang, P.-T., Wang, Q., Chen, R., Wang, Y., Wang, Y.-Y., Liu, J., Xiao, X., & Liao, Z. (2024) · Current Molecular Medicine · doi:10.2174/0115665240270426231123155924 · Cited by 8
TNFSF14-Derived Molecules as a Novel Treatment for Obesity and Type 2 Diabetes
Agostino, M., Rooney, J. K., Herat, L. Y., Matthews, J. R., Simonds, A., Northfield, S. E., Hopper, D., Schlaich, M. P., & Matthews, V. B. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms221910647 · Cited by 8
Yan, G., Wang, Y., Yu, L., Bo, J., Fang, H., Chen, W., Zhang, Y., Chen, H., & Hong, Z. (2025) · Food Research International · doi:10.1016/j.foodres.2025.116008 · Cited by 7
Individualized diabetes care: Lessons from the real-world experience
Khor, X. Y., Pappachan, J. M., & Jeeyavudeen, M. S. (2023) · World Journal of Clinical Cases · doi:10.12998/wjcc.v11.i13.2890 · Cited by 12
Sethi, B. K., Sahay, R. K., TIWASKAR, M. H., Negalur, V. B., Dhediya, R., Gaurav, K., Rathod, R., Kotak, B., Dhanaki, G. D., & Shah, S. P. (2023) · Drugs - Real World Outcomes · doi:10.1007/s40801-023-00398-8 · Cited by 7
Zhang, B., Ren, L., Lu, Y., Wang, Z., Zhang, G., Liu, Z., Wang, Y., Zhu, F., Li, X., Jiang, Y., et al. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.145695 · Cited by 6
Ruddiman, K. R., Bartfield, J. K., & Hirsch, I. B. (2025) · Obesity · doi:10.1002/oby.70033 · Cited by 8
Tirzepatide: unveiling a new dawn in dual-targeted diabetes and obesity management
Rabbani, S. A., El‐Tanani, M., Matalka, I. I., Rangraze, I. R., Aljabali, A. A. A., Khan, M. A., & Tambuwala, M. M. (2024) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2024.2395540 · Cited by 8
Differential Efficacy of Weight Loss Interventions in Patients with Versus Without Diabetes
Losada-Díaz, F., Lizarazo-Bocanegra, S., Perdomo-Lugo, J. J., Gutiérrez-Romero, S. A., Correa-Osio, I., & Mendivil, C. O. (2024) · Diabetes Therapy · doi:10.1007/s13300-024-01646-y · Cited by 7
Beyond weight: Exploring the nexus between obesity and osteoarthritis
Ningtyas, M. C., Ansharullah, B. A., Sutanto, H., & Prajitno, J. H. (2025) · Medicina de Familia SEMERGEN · doi:10.1016/j.semerg.2025.102526 · Cited by 6
Zhu, Z., Bingzheng, F., Yuwei, Y., Yingying, Z., Xu, Z., Chunhua, H., Jing, L., Tang, H., Wanli, L., Zhang, T., et al. (2023) · Artificial Organs · doi:10.1111/aor.14538 · Cited by 6
SGLT2-Inhibitors are Effective and Safe in the Elderly: The SOLD StudyPreprint
Lunati, M. E., Cimino, V., Gandolfi, A., Trevisan, M., Montefusco, L. B., Pastore, I., Pace, C., Betella, N., Favacchio, G., Bulgheroni, M., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4135997 · Cited by 6
Self-citationPetsas, E., Kiouri, D. P., Georgiou, N., Siasos, G., Mavromoustakos, T., & Chasapis, C. T. (2025) · Molecules · doi:10.3390/molecules30214240 · Cited by 6
Korus, S., Cembrowska-Lech, D., Kłoda, K., & Stachowska, E. (2026) · Journal of Translational Medicine · doi:10.1186/s12967-026-07702-4 · Cited by 5
Therapeutic Repurposing of Antidiabetic Drugs in Diabetes-associated Comorbidities
Pathak, K., Pathak, M. P., Saikia, R., Gogoi, U., Das, R. J., Patowary, P., Kaishap, P. P., Bordoloi, S., Das, J., Sarma, H., et al. (2023) · Current Drug Therapy · doi:10.2174/1574885518666230516150404 · Cited by 6
Sun, X., Yang, D., Li, Y., Shi, J., Zhang, X., & Yi, T. (2024) · Peptides · doi:10.1016/j.peptides.2024.171203 · Cited by 5
Moneim, M. M. A., Kamal, M. F., & Hamdy, M. M. A. (2024) · Journal of Fluorescence · doi:10.1007/s10895-024-03954-9 · Cited by 5
Li, Y., Xu, Q., Wang, J., Xin, Y., Zhang, Y., Qin, X., Xu, K., Yang, X., & Wang, X. (2025) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c07282 · Cited by 5
Talebi, S. S., Rezaie, S., Hajmiri, M. S., Zamanirafe, M., Ranjbar, A., Moridi, H., Mirjalili, M., & Mehrpooya, M. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03219-z · Cited by 10
Kawabata, N., Okada, K., Ando, A., Kurashina, T., Takahashi, M., Wakabayashi, T., Nagata, D., Arakawa, Y., Atsuko, H., Kogure, A., et al. (2022) · Journal of Diabetes Investigation · doi:10.1111/jdi.13890 · Cited by 5
The role of the incretin GIP in inflammation
Rossi, G., Bucciarelli, L. G., Cimino, V., & Fiorina, P. (2025) · Journal of Endocrinological Investigation · doi:10.1007/s40618-025-02719-w · Cited by 4
Self-citationValério, C. M., Saraiva, J. F. K., Valente, F., van de Sande‐Lee, S., Rocha, V. Z., Rached, F. H., Drager, L. F., Halpern, B., Júnior, W. S. D. S., Trujilho, F. R., et al. (2025) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-025-01954-8 · Cited by 8
Wang, Y., Liu, J., Verbeke, K., Gasaly, N., Akkerman, R., & de Vos, P. (2026) · Advances in Nutrition · doi:10.1016/j.advnut.2026.100647 · Cited by 6
Mudireddy, R. R., Gundla, R., Shaik, B. B., Bodapati, A., Mahesh, P., Naidu, S. S., Tirumalasetti, D., & Katari, N. K. (2025) · RSC Advances · doi:10.1039/d5ra01971k · Cited by 4
Tosi, M., Matelloni, I. A., Mancini, M., Andreassi, A., Scopari, A., Rossi, A., Verduci, E., Berra, C., Manfrini, R., Banderali, G., et al. (2023) · Journal of Endocrinological Investigation · doi:10.1007/s40618-023-02088-2 · Cited by 5
Self-citation
Metadata
- Authors
- Lazzaroni, E., Ben Nasr, M., Loretelli, C., Pastore, I., Plebani, L., Lunati, M. E., Vallone, L., Bolla, A. M., Rossi, A., Montefusco, L., Ippolito, E., Berra, C., D’Addio, F., Zuccotti, G. V., & Fiorina, P.
- Affiliations
- ASST Fatebenefratelli Sacco (IT)
- University of Milan (IT)
- MultiMedica (IT)
- Boston Children's Hospital (US)
- Corresponding author
- Fiorina, Paolo
- ORCID
- Venue
- Pharmacological Research
- Publisher
- Elsevier BV
- Published
- 2021-09
- Volume
- 171
- Pages
- 105782
- ISSN
- 1043-6618 (ISSN-L)
- OpenAlex
- W3184250385
- Cited by
- 182
- References
- 75
- Citations by year
- 2026: 25 · 2025: 43 · 2024: 41 · 2023: 47 · 2022: 23 · 2021: 3
- FWCI
- 4.38
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Pharmacological Research (publishedVersion)
- PubMed (publishedVersion)
- Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Pharmacology (medical) › Pharmacology and Obesity Treatment
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- type 2 diabetes, weight loss, antidiabetic drugs, diabesity, obesity, GLP-1 receptor agonists, tirzepatide, exenatide, SGLT2 inhibitors, metformin, acarbose, body mass index, body composition
- MeSH terms
- Glucagon-Like Peptide-1 Receptor, Glucagon-Like Peptide-1 Receptor Agonists, Diabetes Mellitus, Type 2, Gastric Inhibitory Polypeptide, Humans, Hypoglycemic Agents, Obesity, Weight Loss, Glucagon-Like Peptide 1
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review