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Cited by 44Inflammatory Bowel DiseaseNatural Compounds in Disease TreatmentPhytochemistry and biological activity of medicinal plants

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Paeoniflorin prevents aberrant proliferation and differentiation of intestinal stem cells by controlling C1q release from macrophages in chronic colitis

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Wang, Yirui, You, Keyuan, You, Yan, Li, Qian, Feng, Guize, Ni, Jiahui, Cao, Xinyue, Zhang, Xiaowen, Wang, Yanhang, Bao, Weilian, Wang, Xu, Chen, Tongqing, Li, Haidong, Huang, Yuran, Lyu, Jiaren, Yu, Shihang, Li, Hong, Xu, Suowen, Zeng, Kewu, Shen, Xiaoyan·2022·Pharmacological Research
DOI 10.1016/j.phrs.2022.106309
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Metadata

Authors
Wang, Y., You, K., You, Y., Li, Q., Feng, G., Ni, J., Cao, X., Zhang, X., Wang, Y., Bao, W., Wang, X., Chen, T., Li, H., Huang, Y., Lyu, J., Yu, S., Li, H., Xu, S., Zeng, K., & Shen, X.
Affiliations
  • Peking University (CN)
  • Fudan University (CN)
  • University of Science and Technology of China (CN)
Corresponding author
  • Xu, Suowen
  • Shen, Xiaoyan
ORCID
Venue
Pharmacological Research
Publisher
Elsevier BV
Published
2022-08
Volume
182
Pages
106309
ISSN
1043-6618 (ISSN-L)
DOI
10.1016/j.phrs.2022.106309
OpenAlex
W4282970381
Cited by
44
References
1
Citations by year
2026: 14 · 2025: 11 · 2024: 13 · 2023: 6
FWCI
5.00
Type
journal article
Language
en
Open access
Licence
Locations
  • Pharmacological Research (publishedVersion)
  • SSRN Electronic Journal (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China (81773744, 81973505, 82070464, 82130108, 82174044)
  • Science and Technology Innovation Plan Of Shanghai Science and Technology Commission (19140901800)
Topics
  • Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
  • Health Sciences › Medicine › Complementary and alternative medicine › Natural Compounds in Disease Treatment
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and biological activity of medicinal plants
Keywords
paeoniflorin, chronic colitis, inflammatory bowel disease, C1q, C1QA, macrophages, intestinal stem cells, Wnt/β-catenin signaling, IL-10 knockout mice, phagocytosis, mucosal healing, herbal medicine
MeSH terms
Animals, Colitis, Disease Models, Animal, Glucosides, Glycosides, Inflammation, Intestinal Mucosa, Macrophages, Mice, Inbred C57BL, Stem Cells, Complement C1q, Dextran Sulfate, Interleukin-10, Monoterpenes, Cell Proliferation, Mice

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