Serum metabolic variables associated with impaired glucose tolerance induced by high-fat-high-cholesterol diet in Macaca mulatta

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502 · see citing works

Glucose clamp technique: a method for quantifying insulin secretion and resistance.

DeFronzo, R. A., Tobin, J. D., & Andres, R. (1979) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1979.237.3.e214 · Cited by 7,425 · see citing works

Global estimates of the prevalence of diabetes for 2010 and 2030

Shaw, J. E., Sicree, R. A., & Zimmet, P. Z. (2010) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2009.10.007 · Cited by 7,216 · see citing works

Lipid-Induced Insulin Resistance in Human Muscle Is Associated With Changes in Diacylglycerol, Protein Kinase C, and IκB-α

Itani, S. I., Ruderman, N. B., Schmieder, F., & Boden, G. (2002) · Diabetes · doi:10.2337/diabetes.51.7.2005 · Cited by 1,390 · see citing works

Cholesterol in the Prediction of Atherosclerotic Disease

Kannel, W. B., Castelli, W. P., & Gordon, T. (1979) · Annals of Internal Medicine · doi:10.7326/0003-4819-90-1-85 · Cited by 1,314 · see citing works

Prospective study of major dietary patterns and risk of coronary heart disease in men

Hu, F. B., Rimm, E. B., Stampfer, M. J., Ascherio, A., Spiegelman, D. L., & Willett, W. C. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.4.912 · Cited by 1,056 · see citing works

Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

Dumas, M.-E., Barton, R. H., Toye, A., Cloarec, O., Blancher, C., Rothwell, A., Fearnside, J., Tatoud, R., Blanc, V., Lindon, J. C., et al. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601056103 · Cited by 1,042 · see citing works

The metabolic syndrome in children and adolescents

Zimmet, P., Alberti, G., KAUFMAN, F. R., Tajima, N., Silink, M., Arslanian, S. A., Wong, G., Bennett, P. H., Shaw, J. E., & Caprio, S. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60958-1 · Cited by 963 · see citing works

Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction

Morino, K., Petersen, K. F., & Shulman, G. I. (2006) · Diabetes · doi:10.2337/db06-s002 · Cited by 853 · see citing works

The relation between insulin sensitivity and the fatty-acid composition of skeletal-muscle phospholipids

Borkman, M., Storlien, L. H., Pan, D. A., Jenkins, A. B., Chisholm, D. J., & Campbell, L. V. (1993) · New England Journal of Medicine · doi:10.1056/nejm199301283280404 · Cited by 835 · see citing works

The perils of portliness: causes and consequences of visceral adiposity.

Montague, C. T., & O’Rahilly, S. (2000) · Diabetes · doi:10.2337/diabetes.49.6.883 · Cited by 735 · see citing works

Progress and Challenges in Metabolic Syndrome in Children and Adolescents

Steinberger, J., Daniels, S. R., Eckel, R. H., Hayman, L. L., Lustig, R. H., McCrindle, B. W., & Mietus‐Snyder, M. (2009) · Circulation · doi:10.1161/circulationaha.108.191394 · Cited by 713 · see citing works

Defining high-fat-diet rat models: Metabolic and molecular effects of different fat types

Buettner, R., Parhofer, K. G., Woenckhaus, M., Wrede, C. E., Kunz-Schughart, L. A., Schölmerich, J., & Bollheimer, L. C. (2006) · Journal of Molecular Endocrinology · doi:10.1677/jme.1.01909 · Cited by 704 · see citing works

Dietary Fat and Meat Intake in Relation to Risk of Type 2 Diabetes in Men

van Dam, R. M., Willett, W. C., Rimm, E. B., Stampfer, M. J., & Hu, F. B. (2002) · Diabetes Care · doi:10.2337/diacare.25.3.417 · Cited by 593 · see citing works

Saturated Fatty Acids Synergize with Elevated Glucose to Cause Pancreatic β-Cell Death

El-Assaad, W., Buteau, J., Peyot, M., Nolan, C. J., Roduit, R., Hardy, S., Joly, E. C., Dbaibo, G. S., Rosenberg, L. C., & Prentki, M. (2003) · Endocrinology · doi:10.1210/en.2003-0410 · Cited by 586 · see citing works

Analytical Strategies in Metabonomics

Lenz, E. M., & Wilson, I. D. (2006) · Journal of Proteome Research · doi:10.1021/pr0605217 · Cited by 530 · see citing works

Lipid accumulation in non-adipose tissue and lipotoxicity

van Herpen, N. A., & Schrauwen-Hinderling, V. B. (2008) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.11.049 · Cited by 500 · see citing works

Choline deficiency: A cause of hepatic steatosis during parenteral nutrition that can be reversed with intravenous choline supplementation

Buchman, A. L., Dubin, M. D., Moukarzel, A. A., Jenden, D. J., Roch, M., Rice, K. M., Gornbein, J. A., & Ament, M. E. (1995) · Hepatology · doi:10.1002/hep.1840220510 · Cited by 333 · see citing works

Intracellular cholesterol transport

Fielding, C. J., & Fielding, P. E. (1997) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)37169-8 · Cited by 291 · see citing works

Use of relaxation-edited one-dimensional and two dimensional nuclear magnetic resonance spectroscopy to improve detection of small metabolites in blood plasma

Tang, H., Wang, Y. L., Nicholson, J. K., et al. (2004) · Analytical Biochemistry · doi:10.1016/j.ab.2003.10.033 · Cited by 229 · see citing works

Predictors of body mass index and associations with cardiovascular risk factors in Australian children: a prospective cohort study

Burke, V., Beilin, L. J., Simmer, K. N., Oddy, W. H., Blake, K. V., Doherty, D. A., Kendall, G. E., Newnham, J. P., Landau, L. I., & Stanley, F. (2004) · International Journal of Obesity · doi:10.1038/sj.ijo.0802750 · Cited by 173 · see citing works

Human Serum Metabonomic Analysis Reveals Progression Axes for Glucose Intolerance and Insulin Resistance Statuses

Zhang, X., Wang, Y., Hao, F., Zhou, X., Han, X., Tang, H., & Ji, L. (2009) · Journal of Proteome Research · doi:10.1021/pr900524z · Cited by 147 · see citing works

Elevated high density lipoprotein cholesterol levels correlate with decreased apolipoprotein A-I and A-II fractional catabolic rate in women.

Brinton, E. A., Eisenberg, S., & Breslow, J. L. (1989) · Journal of Clinical Investigation · doi:10.1172/jci114149 · Cited by 139 · see citing works

The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys

van Heek, M., Compton, D. S., & Davis, H. R. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)00825-1 · Cited by 130 · see citing works

Update on Dyslipidemia

Garg, A., & Simha, V. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0275 · Cited by 120 · see citing works

Diagnosing Inborn Errors of Lipid Metabolism with Proton Nuclear Magnetic Resonance Spectroscopy

Oostendorp, M., Engelke, U. F. H., Willemsen, M. A., & Wevers, R. A. (2006) · Clinical Chemistry · doi:10.1373/clinchem.2006.069112 · Cited by 105 · see citing works

Glucose-Induced Preproinsulin Gene Expression Is Inhibited by the Free Fatty Acid Palmitate1

Ritz-Laser, B., Meda, P., Constant, I., Klages, N., Charollais, A., Morales, A., Magnan, C., Ktorza, A., & Philippé, J. (1999) · Endocrinology · doi:10.1210/endo.140.9.6953 · Cited by 103 · see citing works

Global health status: two steps forward, one step back

Sen, K., & Bonita, R. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02590-3 · Cited by 101 · see citing works

Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human

Magness, C. L., Fellin, P. C., Thomas, M. J., Korth, M. J., Agy, M. B., Proll, S. C., Fitzgibbon, M., Scherer, C., Miner, D. G., Katze, M. G., et al. (2005) · Genome biology · doi:10.1186/gb-2005-6-7-r60 · Cited by 92 · see citing works

High-fat diet without excess calories induces metabolic disorders and enhances atherosclerosis in rabbits

Waqar, A. B., Koike, T., Yu, Y., Inoue, T., Aoki, T., Liu, E., & Fan, J. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.07.051 · Cited by 79 · see citing works

The Cholesterol Content of Western Diets Plays a Major Role in the Paradoxical Increase in High-Density Lipoprotein Cholesterol and Upregulates the Macrophage Reverse Cholesterol Transport Pathway

Escolá‐Gil, J. C., Llaverı́as, G., Julve, J., et al. (2011) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.111.236075 · Cited by 79 · see citing works

Changes in satiety hormones and expression of genes involved in glucose and lipid metabolism in rats weaned onto diets high in fibre or protein reflect susceptibility to increased fat mass in adulthood

Maurer, A. D., Chen, Q., McPherson, C., & Reimer, R. A. (2008) · The Journal of Physiology · doi:10.1113/jphysiol.2008.161844 · Cited by 72 · see citing works

Effect of egg cholesterol and dietary fats on plasma lipids, lipoproteins, and apoproteins of normal women consuming natural diets

Zanni, E. E., Zannis, V. I., Blum, C. B., Herbert, P. N., & Breslow, J. L. (1987) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)38680-6 · Cited by 68 · see citing works

Cholesterol metabolism in groups of rhesus monkeys with high or low response of serum cholesterol to an atherogenic diet

Eggen, D. A. (1976) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41739-0 · Cited by 68 · see citing works

Analysis of plasma lipids by NMR spectroscopy: application to modifications induced by malignant tumors

Kriat, M., Vion‐Dury, J., Confort‐Gouny, S., et al. (1993) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39686-3 · Cited by 66 · see citing works

Dietary Lipids Influence Insulin Action a

Clandinin, M. T., Cheema, S. K., Field, C. J., & Baracos, V. E. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb35701.x · Cited by 65 · see citing works

Energy Intake and Utilization Vary During Development in Rats

Iossa, S., Lionetti, L., Mollica, M. P., Barletta, A., & Liverini, G. (1999) · Journal of Nutrition · doi:10.1093/jn/129.8.1593 · Cited by 64 · see citing works

Lipidomic changes in rat liver after long-term exposure to ethanol

Fernando, H., Bhopale, K. K., Kondraganti, S., et al. (2011) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2011.05.022 · Cited by 60 · see citing works

Cholesterol metabolism in rhesus monkey, squirrel monkey, and baboon

Eggen, D. A. (1974) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)36816-4 · Cited by 57 · see citing works

1H NMR metabonomics can differentiate the early atherogenic effect of dairy products in hyperlipidemic hamsters

Martin, J., Canlet, C., Delplanque, B., Agnani, G., Lairon, D., Gottardi, G., Bencharif, K., Gripois, D., Thaminy, A., & Paris, A. (2009) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2009.01.040 · Cited by 55 · see citing works

Adverse metabolic effects of a hypercaloric, high-fat diet in rodents precede observable changes in body weight

McDonald, S. D., Pesarchuk, E., Don-Wauchope, A., Zimaity, H. E., & Holloway, A. C. (2011) · Nutrition Research · doi:10.1016/j.nutres.2011.08.009 · Cited by 36 · see citing works

Prolonged hyperphagia with high-fat feeding contributes to exacerbated weight gain in rats with adult-onset obesity

Judge, M. K., Zhang, J., Tümer, N., Carter, C., Daniels, M. J., & Scarpace, P. J. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00727.2007 · Cited by 35 · see citing works

Accelerating progress on non-communicable diseases

Sacco, R., Sc, S., Holmes, D. R., et al. (2011) · The Lancet · doi:10.1016/s0140-6736(11)61477-3 · Cited by 34 · see citing works

Sphingolipids: major regulators of lipid metabolism

Worgall, T. S. (2007) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0b013e328028fda3 · Cited by 32 · see citing works

Nuclear magnetic resonance–determined lipoprotein abnormalities in nonhuman primates with the metabolic syndrome and type 2 diabetes mellitus

Ding, S.-Y., Tigno, X. T., & HANSEN, B. C. (2007) · Metabolism · doi:10.1016/j.metabol.2007.01.015 · Cited by 30 · see citing works

Glucose disappearance rate in rhesus monkeys: Some technical considerations

Jen, K.-L. C., & HANSEN, B. C. (1988) · American Journal of Primatology · doi:10.1002/ajp.1350140206 · Cited by 29 · see citing works

Boom Time for Monkey Research

Pennisi, E. (2007) · Science · doi:10.1126/science.316.5822.216 · Cited by 18 · see citing works

Endogenous and diet-induced hypercholesterolemia in nonhuman primates: effects of age, adiposity, and diabetes on lipoprotein profiles

Shamekh, R., Linden, E. H., Newcomb, J. D., Tigno, X. T., Jen, K. C., Pellizzon, M., & HANSEN, B. C. (2011) · Metabolism · doi:10.1016/j.metabol.2010.12.012 · Cited by 17 · see citing works

Correlations of Hemoglobin A1c and Metabolic Status in Nondiabetic, Borderline Diabetic, and Diabetic Macaca Nigra

Howard, C. F. (1982) · Diabetes · doi:10.2337/diacare.31.12.1105 · Cited by 16 · see citing works

Studies on the Metabolic Effects Induced in the Rat by a High-Fat Diet. Control of Glucose Metabolism in Adipose Tissue of Fed and Fasted Rats

Zaragoza‐Hermans, N. M. (1974) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1974.tb03800.x · Cited by 10 · see citing works

Trimethylamine <i>N</i> -Oxide, the Microbiome, and Heart and Kidney Disease

Zeisel, S. H., & Warrier, M. (2017) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-071816-064732 · Cited by 475 · see citing works

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

Gao, X., Liu, X., Xu, J., Xue, C., Xue, Y., & Wang, Y. (2014) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2014.03.001 · Cited by 360 · see citing works

Fish oil ameliorates trimethylamine N-oxide-exacerbated glucose intolerance in high-fat diet-fed mice

Gao, X., Xu, J., Jiang, C., Zhang, Y., Xue, Y., Li, Z., Wang, J., Xue, C., & Wang, Y. (2015) · Food &amp; Function · doi:10.1039/c5fo00007f · Cited by 60 · see citing works

Exogenous Glucocorticoids and a High-Fat Diet Cause Severe Hyperglycemia and Hyperinsulinemia and Limit Islet Glucose Responsiveness in Young Male Sprague-Dawley Rats

Beaudry, J. L., D'souza, A. M., Teich, T., Tsushima, R. G., & Riddell, M. C. (2013) · Endocrinology · doi:10.1210/en.2012-2114 · Cited by 44 · see citing works

The Effect of Fasting on Tissue Cyclic cAMP and Plasma Glucagon in the Obese Hyperglycemic Mouse

VINE, R. L. L., Voyles, N. R., Perrino, P. V., & Recant, L. (1975) · Endocrinology · doi:10.1210/endo-97-3-615 · Cited by 38 · see citing works

Modulation of Adipoinsular Axis in Prediabetic Zucker Diabetic Fatty Rats by Diazoxide

Alemzadeh, R., & Tushaus, K. (2004) · Endocrinology · doi:10.1210/en.2003-1523 · Cited by 38 · see citing works

The Paraventricular Nucleus of the Hypothalamus Has a Major Role in Thyroid Hormone Feedback Regulation of Thyrotropin Synthesis and Secretion

Taylor, T., Wondisford, F. E., Blaine, T. A., & Weintraub, B. D. (1990) · Endocrinology · doi:10.1210/endo-126-1-317 · Cited by 54 · see citing works

Growth hormone binding protein in the rat: effects of gonadal steroids

Carmignac, D. F., Gabrielsson, B. G., & Robinson, I. C. A. F. (1993) · Endocrinology · doi:10.1210/endo.133.6.8243263 · Cited by 68 · see citing works