Cited by 20Pregnancy and preeclampsia studiesIon channel regulation and functionCardiac electrophysiology and arrhythmias

Review: Potassium channels in the human fetoplacental vasculature

Wareing, M., Greenwood, S.L.·2011·Placenta

Abstract

Despite their fundamental importance for normal cellular function, potassium (K) channels have been poorly studied in placental vascular tissues. This lack of experimental focus may relate to the fact that, as yet, no pregnancy complications have been directly attributable to a specific "channelopathy". K channel activity is central to normal cellular function. Vascular smooth muscle and endothelial cells within the fetoplacental circulation would be expected to be heavily influenced by the behaviour of K channels, as has been well-documented in other vascular beds. In this review, we summarise current understanding of K channel expression and activity in fetoplacental vasculature in normal and complicated pregnancies.

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Crossref · 10.1016/j.placenta.2010.12.022

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42 of 42 references verified0 citation errors · 0 not checkable

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  • A variety of K+ channel subtypes, many of them oxygen sensitive, are present in the vasculature of the human placenta.

    “A variety of K + channel subtypes, many of them oxygen sensitive, are present in the vasculature of the human placenta (307, 563, 564).”

    From Placental Origins of Chronic Disease (2016) · cites this paper as [564]

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Authors
Wareing, M., & Greenwood, S. L.
Affiliations
University of Manchester (GB)
Corresponding author
Wareing, M.
Venue
Placenta
Publisher
Elsevier BV
Published
2011-03
Volume
32
Pages
S203-S206
ISSN
0143-4004 (ISSN-L)
OpenAlex
W2145849863
Cited by
20
References
42
Citations by year
2026: 1 · 2025: 2 · 2023: 2 · 2020: 2 · 2019: 2 · 2016: 2 · 2014: 1 · 2013: 5 · 2012: 2
FWCI
3.71
Type
journal article
Language
en
Open access
closed
Locations
  • Placenta (publishedVersion)
  • PubMed (publishedVersion)
  • Research Explorer (The University of Manchester) (publishedVersion)
Funders
  • British Heart Foundation
  • Action Medical Research
Topics
  • Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion channel regulation and function
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords
potassium channels, fetoplacental circulation, placental vasculature, vascular smooth muscle, endothelial cells, pregnancy complications, channelopathies
MeSH terms
Endothelium, Vascular, Female, Humans, Muscle, Smooth, Vascular, Placenta, Pregnancy, Pregnancy Complications, Potassium Channels

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