The effect of developmental and environmental factors on secondary metabolites in medicinal plants
Open accessAbstract
Secondary metabolites (SMs) of medicinal plants are the material basis of their clinically curative effects. They are also important indicators for evaluating the quality of medicinal materials. However, the synthesis and accumulation of SMs are very complex, which are affected by many factors including internal developmental genetic circuits (regulated gene, enzyme) and by external environment factors (light, temperature, water, salinity, etc.). Currently, lots of literatures focused on the effect of environmental factors on the synthesis and accumulation of SMs of medicinal plants, the effect of the developmental growth and genetic factors on the synthesis and accumulation of SMs still lack systematic classification and summary. Here, we have given the review base on our previous works on the morphological development of medicinal plants and their secondary metabolites, and systematically outlined the literature reports how different environmental factors affected the synthesis and accumulation of SMs. The results of our reviews can know how developmental and environmental factors qualitatively and quantitatively influence SMs of medicinal plants and how these can be integrated as tools to quality control, as well as on the improvement of clinical curative effects by altering their genomes, and/or growth conditions.
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The quality and efficacy of herbal medicines can be markedly different for species that have different varieties even when grown under identical geographical and climatic conditions.
“The quality and efficacy can be markedly different for species that have different varieties even when grown under identical geographical and climatic conditions [9].”
From Rapid metabolic fingerprinting with the aid of chemometric models to identify authenticity of natural medicines: Turmeric, Ocimum, and Withania somnifera study (2023) · cites this paper as [9]
Section 2.1 (page unavailable) says genetic factors affect the synthesis and accumulation of medicinal plants’ secondary metabolites, and the Introduction links these compounds to quality control and clinical effects. The paper does not establish that different varieties have markedly different quality and efficacy when grown under identical geographical and climatic conditions. (LLM, conf=0.82)
Experimental — accuracy not yet measuredThe secondary metabolite profile of natural medicines is highly dependent on geographical origin, genotype, and chemotype, including species and variety.
“However, the secondary metabolite profile is highly dependent on the geographical origin, genotype, and chemotype, including the species and variety of natural medicine [9].”
From Rapid metabolic fingerprinting with the aid of chemometric models to identify authenticity of natural medicines: Turmeric, Ocimum, and Withania somnifera study (2023) · cites this paper as [9]
Section 3.5 says geographical origin influences secondary metabolites and notes that plants with different genotypes may respond differently. Section 2.1 also identifies species specificity as a genetic factor in their synthesis and accumulation. The paper does not establish variety or chemotype as determinants of the metabolite profile; chemotypes appear only in a reference title. (LLM, conf=0.87)
Experimental — accuracy not yet measuredHerbal medicines derived from different species have very different therapeutic performances due to different bioactive constituents.
“Furthermore, some herbal medicines are derived from different species and, as a result, have very different therapeutic performances due to different bioactive constituents.”
From Rapid metabolic fingerprinting with the aid of chemometric models to identify authenticity of natural medicines: Turmeric, Ocimum, and Withania somnifera study (2023) · cites this paper as [9]
The Introduction says that secondary metabolites underpin herbal remedies and that chemical constituents have biological activity. Section 2.1 says species specificity affects the synthesis and accumulation of those metabolites. The paper does not establish that herbal medicines from different species have very different therapeutic performances as a result. (LLM, conf=0.82)
Experimental — accuracy not yet measuredHerbal medicines from different species may have very similar morphological characteristics and could be prone to misclassification.
“However, they may have very similar morphological characteristics and could be prone to misclassification [9].”
From Rapid metabolic fingerprinting with the aid of chemometric models to identify authenticity of natural medicines: Turmeric, Ocimum, and Withania somnifera study (2023) · cites this paper as [9]
The Introduction and section 2.1 discuss medicinal plants’ chemical constituents, morphogenesis, and species-specific metabolite production, but not whether different species look alike or are misclassified. Searches for morphological similarity, identification, and misclassification found no passage addressing that claim. The indexed passages provide section labels but no page numbers. (LLM, conf=0.73)
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Cites
Chlorophyll fluorescence—a practical guide
Maxwell, K., & Johnson, G. N. (2000) · Journal of Experimental Botany · doi:10.1093/jexbot/51.345.659 · Cited by 9,347 · see citing works
Influence of abiotic stress signals on secondary metabolites in plants
Ramakrishna, A., & Ravishankar, G. A. (2011) · Plant Signaling & Behavior · doi:10.4161/psb.6.11.17613 · Cited by 2,526 · see citing works
Kilian, J., Whitehead, D., Horak, J., Wanke, D., Weinl, S., Batistič, O., D’Angelo, C., Bornberg‐Bauer, E., Kudla, J., & Harter, K. (2007) · The Plant Journal · doi:10.1111/j.1365-313x.2007.03052.x · Cited by 1,420 · see citing works
Transcription factors in plant defense and stress responses
Singh, K. B. (2002) · Current Opinion in Plant Biology · doi:10.1016/s1369-5266(02)00289-3 · Cited by 1,409 · see citing works
Factors affecting secondary metabolite production in plants: volatile components and essential oils
Figueiredo, A. C., Barroso, J. G., Pedro, L. G., & Scheffer, J. J. C. (2008) · Flavour and Fragrance Journal · doi:10.1002/ffj.1875 · Cited by 1,377 · see citing works
Plant adaptations to the combination of drought and high temperatures
Zandalinas, S. I., Mittler, R., Balfagón, D., Arbona, V., & Gómez‐Cadenas, A. (2018) · Physiologia Plantarum · doi:10.1111/ppl.12540 · Cited by 1,179 · see citing works
Glutathione in plants: biosynthesis and physiological role in environmental stress tolerance
Hasanuzzaman, M., Nahar, K., Anee, T. I., & Fujita, M. (2017) · Physiology and Molecular Biology of Plants · doi:10.1007/s12298-017-0422-2 · Cited by 907 · see citing works
Secretory tissues in vascular plants
Fahn, A. (1988) · New Phytologist · doi:10.1111/j.1469-8137.1988.tb04159.x · Cited by 711 · see citing works
Impact of various factors responsible for fluctuation in plant secondary metabolites
Verma, N., & Shukla, S. (2015) · Journal of Applied Research on Medicinal and Aromatic Plants · doi:10.1016/j.jarmap.2015.09.002 · Cited by 599 · see citing works
Cold stress tolerance mechanisms in plants. A review
Yadav, S. K. (2009) · Agronomy for Sustainable Development · doi:10.1051/agro/2009050 · Cited by 571 · see citing works
Role of Secondary Metabolites and Brassinosteroids in Plant Defense Against Environmental Stresses
Bartwal, A., Mall, R., Lohani, P., Guru, S. K., & Arora, S. (2012) · Journal of Plant Growth Regulation · doi:10.1007/s00344-012-9272-x · Cited by 510 · see citing works
Dudareva, N., Martin, D., Kish, C. M., Kolosova, N. P., Gorenstein, N., Fäldt, J., Miller, B., & Bohlmann, J. (2003) · The Plant Cell · doi:10.1105/tpc.011015 · Cited by 467 · see citing works
Abreu, I. N., & Mazzafera, P. (2005) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2005.01.020 · Cited by 438 · see citing works
Physiological and biochemical responses to high light and temperature stress in plants
Szymańska, R., Ślesak, I., Orzechowska, A., & Kruk, J. (2017) · Environmental and Experimental Botany · doi:10.1016/j.envexpbot.2017.05.002 · Cited by 391 · see citing works
Transcriptional regulation of secondary metabolite biosynthesis in plants
Patra, B., Schluttenhofer, C. M., Wu, Y., et al. (2013) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2013.09.006 · Cited by 357 · see citing works
Investigation of ginsenosides in different parts and ages of Panax ginseng
Shi, W. S., WANG, Y., Li, J., et al. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2006.05.053 · Cited by 261 · see citing works
Król-Grzymała, A., Amarowicz, R., & Weidner, S. (2014) · Acta Physiologiae Plantarum · doi:10.1007/s11738-014-1526-8 · Cited by 258 · see citing works
Medicinal Plants (Importance and Uses)
Hassan, B. A. R. (2012) · Pharmaceutica Analytica Acta · doi:10.4172/2153-2435.1000e139 · Cited by 245 · see citing works
Nagegowda, D. A., Gutensohn, M., Wilkerson, C. G., et al. (2008) · The Plant Journal · doi:10.1111/j.1365-313x.2008.03496.x · Cited by 241 · see citing works
Cheng, L., Han, M., Yang, L., Li, Y., Sun, Z., & Zhang, T. (2018) · Industrial Crops and Products · doi:10.1016/j.indcrop.2018.06.030 · Cited by 192 · see citing works
Self-citationSystems biology of antibiotic production by microorganisms
Rokem, J. S., Lantz, A. E., & NIELSEN, J. K. (2007) · Natural Product Reports · doi:10.1039/b617765b · Cited by 186 · see citing works
Altitudinal variation of secondary metabolite profiles in flowering heads of Arnica montana cv. ARBO
Spitaler, R., Schlorhaufer, P. D., Ellmerer, E. P., Merfort, I., Bortenschlager, S., Stuppner, H., & Zidorn, C. (2006) · Phytochemistry · doi:10.1016/j.phytochem.2005.11.018 · Cited by 161 · see citing works
Time of day modulates low‐temperature Ca2+ signals in Arabidopsis
Dodd, A. N., Jakobsen, M. K., Baker, A. J., et al. (2006) · The Plant Journal · doi:10.1111/j.1365-313x.2006.02933.x · Cited by 159 · see citing works
Lepelley, M., Cheminade, G., Trémillon, N., Simkin, A. J., Caillet, V., & McCarthy, J. (2007) · Plant Science · doi:10.1016/j.plantsci.2007.02.004 · Cited by 151 · see citing works
Jaafar, H. Z. E., Ibrahim, M. H., & Fakri, N. F. M. (2012) · Molecules · doi:10.3390/molecules17067305 · Cited by 142 · see citing works
Neffati, M., & Marzouk, B. (2008) · Industrial Crops and Products · doi:10.1016/j.indcrop.2008.02.005 · Cited by 135 · see citing works
Gregoriou, K., Pontikis, K. A., & Vemmos, S. N. (2007) · Photosynthetica · doi:10.1007/s11099-007-0029-x · Cited by 132 · see citing works
Wang, X., Ren, J., Zhang, A., Sun, H. J., Yan, G., Han, Y., & Liu, L. (2019) · Mass Spectrometry Reviews · doi:10.1002/mas.21589 · Cited by 129 · see citing works
Wu, Z., Li, H., Yang, Y., Zhan, Y., & Tu, D. (2013) · Industrial Crops and Products · doi:10.1016/j.indcrop.2013.02.015 · Cited by 123 · see citing works
Species-specific and leaf-age dependent effects of ultraviolet radiation on two Brassicaceae
Reifenrath, K., & Müller, C. (2007) · Phytochemistry · doi:10.1016/j.phytochem.2006.12.008 · Cited by 120 · see citing works
Variations in essential oil yield and composition during Cinnamomum cassia bark growth
Geng, S., Cui, Z.-X., Huang, X., Chen, Y., Xu, D., & Xiong, P. (2010) · Industrial Crops and Products · doi:10.1016/j.indcrop.2010.10.018 · Cited by 115 · see citing works
Hosseini, M. S., Samsampour, D., Ebrahimi, M., et al. (2018) · Phytochemistry · doi:10.1016/j.phytochem.2018.08.018 · Cited by 111 · see citing works
Takshak, S., & Agrawal, S. B. (2014) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2014.08.011 · Cited by 109 · see citing works
Effect of drought stress on metabolite adjustments in drought tolerant and sensitive thyme
Ashrafi, M., Azimi-Moqadam, M.-R., Moradi, P., et al. (2018) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2018.09.009 · Cited by 108 · see citing works
Gupta, N., Sharma, S. K., Rana, J. C., & Chauhan, R. S. (2011) · Journal of Plant Physiology · doi:10.1016/j.jplph.2011.06.018 · Cited by 102 · see citing works
Lavola, A., Julkunen‐Tiitto, R., de la Rosa, T. M., et al. (2000) · Physiologia Plantarum · doi:10.1034/j.1399-3054.2000.100306.x · Cited by 102 · see citing works
An Omics Approach to Understand the Plant Abiotic Stress
Debnath, M., Pandey, M., & Bisen, P. S. (2011) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2010.0146 · Cited by 102 · see citing works
Ma, Z., Li, S., Zhang, M., et al. (2010) · HortScience · doi:10.21273/hortsci.45.6.863 · Cited by 101 · see citing works
Baâtour, O., Kaddour, R., Wannes, W. A., et al. (2009) · Acta Physiologiae Plantarum · doi:10.1007/s11738-009-0374-4 · Cited by 101 · see citing works
Kong, D., Li, Y., Wang, M.-L., et al. (2016) · Acta Physiologiae Plantarum · doi:10.1007/s11738-016-2147-1 · Cited by 100 · see citing works
Self-citationLi, Y., De, K., Huang, R., et al. (2013) · Industrial Crops and Products · doi:10.1016/j.indcrop.2013.02.031 · Cited by 97 · see citing works
Self-citationPhotosynthesis: Structures, Mechanisms, and Applications
Allakhverdiev, S. I., Moore, G. F., Najafpour, M. M., et al. (2017) · Springer eBooks · doi:10.1007/978-3-319-48873-8 · Cited by 96 · see citing works
Kurepin, L. V., Ivanov, A. G., Zaman, M., et al. (2017) · Springer eBooks · doi:10.1007/978-3-319-48873-8_9 · Cited by 94 · see citing works
Transcriptional regulation of salinity stress in plants: A short review
Kumar, J., Singh, S., Singh, M., et al. (2017) · Plant Gene · doi:10.1016/j.plgene.2017.04.001 · Cited by 90 · see citing works
Seasonal variation in the chemical composition of two chemotypes of Lippia alba
Gomes, A. F., de Almeida, M. P., Leite, M. F., et al. (2017) · Food Chemistry · doi:10.1016/j.foodchem.2017.11.089 · Cited by 89 · see citing works
Vázquez-León, L. A., Páramo-Calderón, D. E., Robles-Olvera, V. J., Valdés-Rodríguez, O. A., Pérez-Vázquez, A., García-Alvarado, M. A., & Rodríguez-Jimenes, G. C. (2017) · European Food Research and Technology · doi:10.1007/s00217-017-2868-4 · Cited by 86 · see citing works
Xu, C.-G., Tang, T.-X., Chen, R., et al. (2013) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-013-0406-z · Cited by 85 · see citing works
Li, Q., Lei, S., Du, K., et al. (2016) · Scientific Reports · doi:10.1038/srep36463 · Cited by 85 · see citing works
UV-B-mediated flavonoid synthesis in white asparagus (Asparagus officinalis L.)
Eichholz, I., Rohn, S., Gamm, A., Beesk, N., Herppich, W. B., Kroh, L. W., Ulrichs, C., & Huyskens-Keil, S. (2012) · Food Research International · doi:10.1016/j.foodres.2012.03.008 · Cited by 80 · see citing works
Li, Y., Kong, D., Bai, M., et al. (2019) · Horticulture Research · doi:10.1038/s41438-019-0154-2 · Cited by 78 · see citing works
Self-citationPan, W. S., Zheng, L. P., Tian, H., Li, W. Y., & Wang, J. (2014) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2014.08.013 · Cited by 75 · see citing works
Kong, D., Li, Y., Bai, M., et al. (2016) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2016.12.027 · Cited by 72 · see citing works
Self-citationZahra Haghighi (2012) · Journal of Medicinal Plants Research · doi:10.5897/jmpr12.159 · Cited by 71 · see citing works
Photorhabdus ‐nematode symbiosis is dependent on hfq ‐mediated regulation of secondary metabolites
Tobias, N. J., Heinrich, A. K., Eresmann, H., Wright, P. R., Neubacher, N., Backofen, R., & Bode, H. B. (2016) · Environmental Microbiology · doi:10.1111/1462-2920.13502 · Cited by 68 · see citing works
Kong, D., Li, Y., Bai, M., et al. (2016) · Industrial Crops and Products · doi:10.1016/j.indcrop.2016.11.024 · Cited by 66 · see citing works
Self-citationChanges in potato phenylpropanoid metabolism during tuber development
Navarre, D. A., Payyavula, R. S., Shakya, R., Knowles, N. R., & Pillai, S. S. (2013) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2013.01.007 · Cited by 65 · see citing works
Broun, P., Liu, Y., Queen, E., et al. (2006) · Phytochemistry Reviews · doi:10.1007/s11101-006-9000-x · Cited by 60 · see citing works
Genetic Diversity and Variation of Saponin Contents in Panax notoginseng Roots from a Single Farm
Hong, D. Y. Q., Lau, A. J., Yeo, C. L., et al. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf051248g · Cited by 59 · see citing works
Singh, N., & Sharma, A. K. (2017) · Comptes Rendus Biologies · doi:10.1016/j.crvi.2017.09.009 · Cited by 59 · see citing works
Estell, R. E., Fredrickson, E. L., & James, D. K. (2016) · Biochemical Systematics and Ecology · doi:10.1016/j.bse.2016.02.019 · Cited by 55 · see citing works
Xu, J., Yu, Y., Shi, R., et al. (2018) · Molecules · doi:10.3390/molecules23020428 · Cited by 55 · see citing works
Ma, C. H., Chu, J. Z., Shi, X. F., et al. (2016) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2016.02.019 · Cited by 53 · see citing works
Zhou, R., Su, W., Zhang, G. F., et al. (2015) · Photosynthetica · doi:10.1007/s11099-016-0074-4 · Cited by 51 · see citing works
Li, Y., Kong, D., Lin, X., et al. (2015) · Food Analytical Methods · doi:10.1007/s12161-015-0187-6 · Cited by 51 · see citing works
Self-citationLiang, S., Wu, H., Xuan, L., et al. (2006) · Journal of Integrative Plant Biology · doi:10.1111/j.1744-7909.2006.00230.x · Cited by 48 · see citing works
Self-citationLi, J., & Zheng-hai, H. (2008) · Journal of Integrative Plant Biology · doi:10.1111/j.1744-7909.2008.00764.x · Cited by 42 · see citing works
Volatile oil comparison of cotyledon leaves of chemotypes of Melaleuca alternifolia
Southwell, I. A., & Russell, M. F. (2002) · Phytochemistry · doi:10.1016/s0031-9422(01)00405-8 · Cited by 41 · see citing works
Zhang, L., Guo, Q.-H., Chang, Q. S., et al. (2015) · Photosynthetica · doi:10.1007/s11099-015-0092-7 · Cited by 40 · see citing works
Belkheir, A. K., Gaid, M. M., Liu, B., et al. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00921 · Cited by 40 · see citing works
Genomics Grand for Diversified Plant Secondary Metabolites
Fang, X., Yang, C., Wei, Y. K., Qixia, M., Yang, L., & Chen, X. (2010) · Acta Botanica Yunnanica · doi:10.3724/sp.j.1143.2011.10233 · Cited by 36 · see citing works
El-Azim, W. M. A., & Ahmed, S. (2009) · Research Journal of Agriculture and Biological Sciences · Cited by 34 · see citing works
Rapid discrimination of cultivated Codonopsis lanceolata in different ages by FT-IR and 2DCOS-IR
Zhu, Y., Xu, C., Huang, J., et al. (2014) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2014.01.069 · Cited by 30 · see citing works
Ali, R., El-Feky, S., & Abbas, H. (2007) · Journal of Biological Sciences · doi:10.3923/jbs.2008.171.175 · Cited by 28 · see citing works
Li, H., Huang, W., Wang, G. L., et al. (2016) · Genetics and Molecular Research · doi:10.4238/gmr.15048756 · Cited by 28 · see citing works
Naghiloo, S., Movafeghi, A., Delazar, A., et al. (2012) · PubMed · doi:10.5681/bi.2012.015 · Cited by 26 · see citing works
Hu, M., Bai, M., Ye, W., et al. (2018) · Journal of Oleo Science · doi:10.5650/jos.ess17229 · Cited by 26 · see citing works
Dar, T. A., Uddin, M., Khan, M. M. A., et al. (2016) · Journal of Applied Research on Medicinal and Aromatic Plants · doi:10.1016/j.jarmap.2016.05.003 · Cited by 25 · see citing works
Ma, S., Zhu, G., Yu, F.-L., Zhu, G., Wang, D., Wang, W., & Hou, J. (2017) · Industrial Crops and Products · doi:10.1016/j.indcrop.2017.09.035 · Cited by 24 · see citing works
Li, Y., Kong, D., Liang, H., et al. (2018) · Angewandte Botanik · doi:10.5073/jabfq.2018.091.023 · Cited by 24 · see citing works
Self-citationAsnaashari, S., Dadpour, M. R., Delazar, A., et al. (2012) · PubMed · doi:10.17877/de290r-4964 · Cited by 23 · see citing works
Genomics Grand for Diversified Plant Secondary Metabolites
Xin, X., Fang, Changqing, Yang, Y., Yukun, Wei, Qi-Xia, -, M., LEI, L., Xiao-Ya, et al. (2011) · Acta Scientiarum Naturalium Universitatis Sunyatseni · Cited by 18 · see citing works
Alkaloid Profile in Relation to Different Developmental Stages of Papaver somniferum L.
Shukla, S. K., & Singh, S. (2001) · Cited by 17 · see citing works
Hu, M., Li, Y. Q., Bai, M., et al. (2015) · Trees · doi:10.1007/s00468-015-1245-9 · Cited by 15 · see citing works
Self-citationBiochemical and molecular basis of differentiation in plant tissue culture
Dey, M., Kalia, S., Ghosh, S., et al. (1998) · Cited by 9 · see citing works
Valverde, C. (2016) · Environmental Microbiology · doi:10.1111/1462-2920.13635 · Cited by 2 · see citing works
Flagged first, then by citations
Research works printed but not linked: 9
- Ashraf, M.A., Iqbal, M., Rasheed, R., Hussain, I., Riaz, M., Arif, M.S., 2018. Environmental Stress and Secondary Metabolites in Plants: an Overview. Plant Metabolites and Regulation under Environmental Stress. pp. 153-167.
- Azhar, N., Hussain, B., Ashraf, Y.M., Abbasim, K.Y., 2011. Water stress mediated changes in growth, physiology and secondary metabolites of desi ajwain (Trachyspermum ammi). Pak. J. Bot. 43 (9), 15-19.
- Banerjee, A., Roychoudhury, A., 2017. Effect of Salinity Stress on Growth and Physiology of Medicinal Plants. Medicinal Plants and Environmental Challenges. pp. 177-188.
- Banerjee, A., Roychoudhury, A., 2018. Effect of Salinity Stress on Growth and Physiology of Medicinal Plants. Plant Metabolites and Regulation under Environmental Stress. pp. 153-167.
- Borges, C.V., Minatel, I.O., Gomez-Gomez, H.A., Lima, G.P.P., 2017. Medicinal Plants: Influence of Environmental Factors on the Content of Secondary Metabolites. Medicinal Plants and Environmental Challenges. pp. 259-277.
- Katerova, Z., Todorova, D., Sergiev, I., 2017. Plant Secondary Metabolites and Some Plant Growth Regulators Elicited by UV Irradiation, Light And/or Shade. Medicinal Plants and Environmental Challenges. pp. 97-121.
- Sanchita, Sharma, A., 2018. Gene Expression Analysis in Medicinal Plants under Abiotic Stress Conditions. Plant Metabolites and Regulation under Environmental Stress. pp. 407-414.
- Yang, Z.N., Lu, S.Q., Yu, Z.W., 2012. Comparison analysis of bioactive compunds of Mignolia Rehd. et Wils from different growth ages. Heilongjiang Med. J. 25 (4), 553-555.
- Yin, L., Zhao, C., Huang, Y., Yang, R.Y., Zeng, Q.P., 2008. Abiotic stress-induced ex- pression of artemisinin biosynthesis genes in Artemisia annua L. Chin. J. Appl. Environ. Biol. 14 (1), 1-5.
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Yeshi, K., Crayn, D., Ritmejerytė, E., & Wangchuk, P. (2022) · Molecules · doi:10.3390/molecules27010313 · Cited by 488 · see citing works
Khan, S., Rai, A. K., Singh, A., Singh, S., Dubey, B. K., Lal, R. K., Negi, A. S., Birse, N., Trivedi, P. K., Elliott, C. T., et al. (2023) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2023.04.018 · Cited by 34 · see citing works
“However, they may have very similar morphological characteristics and could be prone to misclassification [9].”
BackgroundInfluential
- Authors
- Li, Y., Kong, D., Fu, Y., Sussman, M. R., & Wu, H.
- Affiliations
- South China Agricultural University (CN)
- University of Wisconsin–Madison (US)
- Corresponding author
- Wu, Hong
- Venue
- Plant Physiology and Biochemistry
- Publisher
- Elsevier BV
- Published
- 2020-03
- Volume
- 148
- Pages
- 80-89
- ISSN
- 0981-9428 (ISSN-L)
- OpenAlex
- W2999693090
- Cited by
- 1,349
- References
- 85
- Citations by year
- 2026: 187 · 2025: 276 · 2024: 284 · 2023: 260 · 2022: 197 · 2021: 114 · 2020: 29
- FWCI
- 14.43
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Plant Physiology and Biochemistry (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Science and Technology Innovation Fund Project on Forestry of Guangdong Province (2017KJ-CX006)
- Nature Science Foundation of China (31870172)
- Technology and Development Project of Finance Department of Guangdong Province, China ([2015]639)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant tissue culture and regeneration
- Health Sciences › Medicine › Complementary and alternative medicine › Traditional Chinese Medicine Analysis
- Keywords
- secondary metabolites, medicinal plants, plant growth stages, environmental factors, light, temperature, water, salinity, morphological development, plant growth conditions
- MeSH terms
- Environment, Plants, Medicinal, Temperature, Water, Salinity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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