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Cited by 475

The DOI matches its Crossref record; 51 of the 51 references it cites were found in a registry or an index.

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

Open access
Bastide, Matthieu F., Meissner, Wassilios G., Picconi, Barbara, Fasano, Stefania, Fernagut, Pierre-Olivier, Feyder, Michael, Francardo, Veronica, Alcacer, Cristina, Ding, Yunmin, Brambilla, Riccardo, Fisone, Gilberto, Jon Stoessl, A., Bourdenx, Mathieu, Engeln, Michel, Navailles, Sylvia, De Deurwaerdère, Philippe, Ko, Wai Kin D., Simola, Nicola, Morelli, Micaela, Groc, Laurent, Rodriguez, Maria-Cruz, Gurevich, Eugenia V., Quik, Maryka, Morari, Michele, Mellone, Manuela, Gardoni, Fabrizio, Tronci, Elisabetta, Guehl, Dominique, Tison, François, Crossman, Alan R., Kang, Un Jung, Steece-Collier, Kathy, Fox, Susan, Carta, Manolo, Angela Cenci, M., Bézard, Erwan·2015·Progress in Neurobiology
DOI 10.1016/j.pneurobio.2015.07.002
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Abstract

Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa (L-dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately experienced by the vast majority of patients. In addition, psychiatric conditions often manifested as compulsive behaviours, are emerging as a serious problem in the management of L-dopa therapy. The present review attempts to provide an overview of our current understanding of dyskinesia and other L-dopa-induced dysfunctions, a field that dramatically evolved in the past twenty years. In view of the extensive literature on LID, there appeared a critical need to re-frame the concepts, to highlight the most suitable models, to review the central nervous system (CNS) circuitry that may be involved, and to propose a pathophysiological framework was timely and necessary. An updated review to clarify our understanding of LID and other L-dopa-related side effects was therefore timely and necessary. This review should help in the development of novel therapeutic strategies aimed at preventing the generation of dyskinetic symptoms.

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Metadata

Authors
Bastide, M. F., Meissner, W. G., Picconi, B., Fasano, S., Fernagut, P.-O., Feyder, M., Francardo, V., Alcacer, C., Ding, Y., Brambilla, R., Fisone, G., Jon Stoessl, A., Bourdenx, M., Engeln, M., Navailles, S., De Deurwaerdère, P., Ko, W. K. D., Simola, N., Morelli, M., Groc, L., Rodriguez, M.-C., Gurevich, E. V., Quik, M., Morari, M., Mellone, M., Gardoni, F., Tronci, E., Guehl, D., Tison, F., Crossman, A. R., Kang, U. J., Steece-Collier, K., Fox, S., Carta, M., Angela Cenci, M., & Bézard, E.
Venue
Progress in Neurobiology
Publisher
Elsevier BV
Published
2015-09
Volume
132
Pages
96-168
ISSN
0301-0082 (ISSN-L)
DOI
10.1016/j.pneurobio.2015.07.002
OpenAlex
W2138389486
Cited by
475
References
51
FWCI
35.84
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease. https://app.cochat.ai/papers/10.1016/j.pneurobio.2015.07.002
The paper
Bastide, M. F., Meissner, W. G., Picconi, B., Fasano, S., Fernagut, P.-O., Feyder, M., Francardo, V., Alcacer, C., Ding, Y., Brambilla, R., Fisone, G., Jon Stoessl, A., Bourdenx, M., Engeln, M., Navailles, S., De Deurwaerdère, P., Ko, W. K. D., Simola, N., Morelli, M., . . . Bézard, E. (2015). Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease. Progress in Neurobiology. https://doi.org/10.1016/j.pneurobio.2015.07.002

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.