The 2021 International Society for the Study of Hypertension in Pregnancy classification, diagnosis & management recommendations for international practice
Open accessAbstract
All units managing hypertensive pregnant women should maintain and review uniform departmental management protocols and conduct regular audits of maternal & fetal outcomes. The cause(s) of pre-eclampsia and the optimal clinical management of the hypertensive disorders of pregnancy remain uncertain; therefore, we recommend that every hypertensive pregnant woman be offered an opportunity to participate in research, clinical trials and follow-up studies.
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Deviance from a physiological trajectory might be intertwined with gestational complications such as hypertensive disorders of pregnancy, fetal growth restriction, and others.
“While these modifications are pivotal to support fetal development, their deviance from a physiological trajectory might be intertwined with some gestational complications such as hypertensive disorders of pregnancy, fetal growth restriction and others [2-5].”
From Trimester-Specific Bioelectrical Impedance Reference Curves in Physiological Pregnancy: Mapping Maternal Body Composition and Hydration Trajectories (2026) · cites this paper as [4]
The available Abstract discusses management of hypertensive pregnancy and says the causes of pre-eclampsia remain uncertain. Searches for physiological adaptations and fetal growth restriction found no passage linking deviations from a normal pregnancy trajectory to those complications; the available copy contains no substantive body text to check further. (LLM, conf=0.70)
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Cites
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2024 ESC Guidelines for the management of elevated blood pressure and hypertension
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Di Martino, D. D., Sabattini, E., Viscioni, L., Cerri, S., Radaelli, T., Ornaghi, S., Belfiore, J., Stampalija, T., Nuredini, R., Privitera, G., et al. (2026) · Nutrients · doi:10.3390/nu18203341
- Authors
- Magee, L. A., Brown, M. A., Hall, D. R., Gupte, S., Hennessy, A., Karumanchi, S. A., Kenny, L. C., McCarthy, F., Myers, J., Poon, L. C., Rana, S., Saito, S., Staff, A. C., Tsigas, E., & von Dadelszen, P.
- Affiliations
- King's College London (GB)
- UNSW Sydney (AU)
- Stellenbosch University (ZA)
- South Western Sydney Local Health District (AU)
- Cedars-Sinai Medical Center (US)
- University of Liverpool (GB)
- University College Cork (IE)
- Manchester Academic Health Science Centre (GB)
- Chinese University of Hong Kong (HK)
- University of Chicago (US)
- University of Toyama (JP)
- Oslo University Hospital (NO)
- Preeclampsia Foundation (US)
- Corresponding author
- Magee, Laura A
- ORCID
- Venue
- Pregnancy Hypertension
- Publisher
- Elsevier BV
- Published
- 2022-03
- Volume
- 27
- Pages
- 148-169
- ISSN
- 2210-7789 (ISSN-L)
- OpenAlex
- W3207420069
- Cited by
- 1,134
- References
- 19
- Citations by year
- 2026: 378 · 2025: 350 · 2024: 238 · 2023: 121 · 2022: 46
- FWCI
- 91.85
- Type
- journal article
- Language
- en
- Open access
- green
- kclpure.kcl.ac.uk
- Licence
- Locations
- Pregnancy Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion)
- Research Portal (King's College London) (submittedVersion, other-oa)
- NORA - Norwegian Open Research Archives (submittedVersion, cc-by-nc-nd)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Psychiatry and Mental health › Neurological Complications and Syndromes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Keywords
- hypertensive disorders of pregnancy, preeclampsia, hypertension in pregnancy, clinical management guidelines, management protocol, maternal and fetal outcomes, auditing, research participation
- MeSH terms
- Antihypertensive Agents, Blood Pressure Determination, Female, Humans, Postnatal Care, Pre-Eclampsia, Pregnancy, Proteinuria, Risk Factors, Societies, Medical, Exercise
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