Hypertensive Disorders of Pregnancy: ISSHP Classification, Diagnosis, and Management Recommendations for International Practice
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Data from the previously published CHIPS supports a target blood pressure goal of 110-135/85 mmHg to reduce the risk of uncontrolled maternal hypertension and minimize impaired fetal growth.
“Data from the previously published Control of Hypertension in Pregnancy Study (CHIPS) supports a target blood pressure goal of 110-135/85 mmHg to reduce the risk of uncontrolled maternal hypertension and minimize impaired fetal growth (125-127).”
From 15. Management of Diabetes in Pregnancy: <i>Standards of Care in Diabetes—2024</i> (2024) · cites this paper as [127]
The CHIPS trial note (page unavailable) says targeting a diastolic BP of 85 mm Hg reduced accelerated maternal hypertension without a demonstrable adverse outcome for babies. But the paper recommends 110–140/85 mm Hg, not 110–135/85, and does not say that this target minimizes impaired fetal growth; it reports no demonstrable adverse outcome for babies. The Antenatal management section also describes the CHIPS tight-control target as 85 mm Hg diastolic and <160 mm Hg systolic. (LLM, conf=0.88)
Experimental — accuracy not yet measuredThere is some evidence from randomized controlled trials that blood-pressure targets during pregnancy should range from 110 to 135 mmHg for systolic blood pressure and 80 to 85 mmHg for diastolic blood pressure.
“There is some evidence from RCTs that BP targets during pregnancy should range from 110 to 135 mmHg for SBP and 80 to 85 mmHg for DBP.228”
From 2023 ESC guidelines for the management of cardiovascular disease in patients with diabetes. (2023) · cites this paper as [228]
The International Society for the Study of Hypertension in Pregnancy specifically recommends antihypertensive therapy to maintain systolic blood pressure between 110 and 140 mmHg and diastolic blood pressure between 80 and 85 mmHg.
“A similar approach is supported by the International Society for the Study of Hypertension in Pregnancy, which speci fi cally recommends use of antihypertensive therapy to maintain systolic blood pressure between 110 and 140 mmHg and diastolic blood pressure between 80 and 85 mmHg (47).”
From 10. Cardiovascular Disease and Risk Management: <i>Standards of Care in Diabetes—2023</i> (2023) · cites this paper as [47]
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- Authors
- Brown, M. A., Magee, L. A., Kenny, L. C., Karumanchi, S. A., McCarthy, F. P., Saito, S., Hall, D. R., Warren, C. E., Adoyi, G., & Ishaku, S.
- Affiliations
- UNSW Sydney (AU)
- King's College London (GB)
- University of Liverpool (GB)
- Beth Israel Deaconess Medical Center (US)
- Cork University Hospital (IE)
- University of Toyama (JP)
- Stellenbosch University (ZA)
- Population Council (US)
- Population Council (IN)
- ORCID
- Venue
- Hypertension
- Published
- 2018-07
- Volume
- 72
- Issue
- 1
- Pages
- 24-43
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W2808237135
- Cited by
- 2,089
- References
- 116
- Citations by year
- 2026: 219 · 2025: 273 · 2024: 269 · 2023: 336 · 2022: 341 · 2021: 297 · 2020: 210 · 2019: 112 · 2018: 23 · 2017: 4
- FWCI
- 26.06
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Psychiatry and Mental health › Neurological Complications and Syndromes
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Keywords
- hypertensive disorders of pregnancy, preeclampsia, gestational hypertension, pregnancy complications
- MeSH terms
- Antihypertensive Agents, Female, Humans, Pregnancy, Blood Pressure Monitoring, Ambulatory, Disease Management, Hypertension, Pregnancy-Induced
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