Breastfeeding and later maternal risk of hypertension and cardiovascular disease – The role of overall and abdominal obesity
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In this study, we examined how any, full, and partial breastfeeding durations were associated with maternal risk of hypertension and cardiovascular disease (CVD), and how prepregnancy body mass index (BMI) and waist circumference 7 years postpartum influenced these associations. A total of 63,260 women with live-born singleton infants in the Danish National Birth Cohort (1996-2002) were included. Interviews during pregnancy and 6 and 18 months postpartum provided information on prepregnancy weight, height, and the duration of full and partial breastfeeding. Waist circumference was self-reported 7 years postpartum. Cox regression models were used to estimate hazard ratios of incident hypertension and CVD, registered in the National Patient Register from either 18 months or 7 years postpartum through 15 years postpartum. Any breastfeeding ≥4 months was associated with 20-30% lower risks of hypertension and CVD compared to <4 months in both normal/underweight and overweight/obese women. At follow-up starting 7 years postpartum, similar risk reductions were observed after accounting for waist circumference adjusted for BMI. Partial breastfeeding >2 months compared to ≤2 months, following up to 6 months of full breastfeeding, was associated with 10-25% lower risk of hypertension and CVD. Compared with short breastfeeding duration, additional partial breastfeeding was as important as additional full breastfeeding in reducing risk of hypertension and CVD. Altogether, longer duration of breastfeeding was associated with lower maternal risk of hypertension and CVD irrespective of prepregnancy BMI and abdominal adiposity 7 years after delivery. Both full and partial breastfeeding contributed to an improved cardiovascular health in mothers.
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A longer length of breastfeeding is associated with a reduced risk of non-fatal composite cardiovascular disease compared with never breastfed in all three cohort studies.
“A longer length of breastfeeding was associated with a reduced risk of non-fatal composite cardiovascular disease compared with never breastfed in all three cohort studies.111 114 116”
From Association between the reproductive health of young women and cardiovascular disease in later life: umbrella review (2020) · cites this paper as [114]
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Abnormale Plazentation: Hypertensive Schwangerschaftserkrankungen
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- Authors
- Kirkegaard, H., Bliddal, M., Støvring, H., Rasmussen, K. M., Gunderson, E. P., Køber, L., Sørensen, T. I. A., & Nohr, E. A.
- Affiliations
- University of Southern Denmark (DK)
- Aarhus University (DK)
- Cornell University (US)
- Kaiser Permanente (US)
- Copenhagen University Hospital (DK)
- University of Copenhagen (DK)
- Corresponding author
- Kirkegaard, H.
- ORCID
- Venue
- Preventive Medicine
- Publisher
- Elsevier BV
- Published
- 2018-09
- Volume
- 114
- Pages
- 140-148
- ISSN
- 0091-7435 (ISSN-L)
- OpenAlex
- W2811205523
- Cited by
- 64
- References
- 42
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 11 · 2023: 8 · 2022: 12 · 2021: 7 · 2020: 8 · 2019: 4 · 2018: 1
- FWCI
- 3.90
- Type
- journal article
- Language
- en
- Open access
- Licence
- cc-by-nc-nd
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Preventive Medicine (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion, cc-by-nc-nd)
- Funders
- March of Dimes Foundation
- Hjerteforeningen
- Sundhed og Sygdom, Det Frie Forskningsråd (SSVF 0646, 195/04)
- National Research Foundation
- Danmarks Grundforskningsfond (SSVF 0646, 195/04)
- Lundbeckfonden (195/04, SSVF 0646)
- Egmont Fonden
- H. Lundbeck A/S
- Medical Research Council (SSVF 0646)
- Topics
- Health Sciences › Medicine › Epidemiology › Breastfeeding Practices and Influences
- Health Sciences › Medicine › Oncology › Cancer Risks and Factors
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Keywords
- breastfeeding duration, hypertension, cardiovascular disease, maternal health, pre-pregnancy body mass index, abdominal obesity, waist circumference, partial breastfeeding, overweight and obesity
- MeSH terms
- Adult, Breast Feeding, Cardiovascular Diseases, Denmark, Female, Humans, Hypertension, Pregnancy, Risk Factors, Body Mass Index, Waist Circumference, Obesity, Abdominal
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