Acer truncatum leaves extract modulates gut microbiota, improves antioxidant capacity, and alleviates lipopolysaccharide-induced inflammation in broilers
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Lachnospiraceae_NK4A136_group may play a role in reducing fat and regulating antioxidant activity.
“suggest that the Lachnospiraceae_NK4A136_group may play a role in reducing fat and regulating antioxidant activity.”
From Spirulina Supplementation Alleviates Intense Exercise-Induced Damage and Modulates Gut Microbiota in Mice (2025) · cites this paper as [36]
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Role of the gut microbiota in nutrition and health
Valdes, A. M., Walter, J., Segal, E., & Spector, T. D. (2018) · BMJ · doi:10.1136/bmj.k2179 · Cited by 2,375 · see citing works
Understanding the mechanism of IL-1β secretion
Lopez-Castejon, G., & Brough, D. (2011) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2011.10.001 · Cited by 1,519 · see citing works
Interaction between the gut microbiome and mucosal immune system
Shi, N., Li, N., Duan, X., & Niu, H. (2017) · Military Medical Research · doi:10.1186/s40779-017-0122-9 · Cited by 940 · see citing works
Daillère, R., Vétizou, M., Waldschmitt, N., Yamazaki, T., Isnard, C., Poirier-Colame, V., Duong, C. P. M., Flament, C., Lepage, P., Roberti, M. P., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.09.009 · Cited by 897 · see citing works
Bai, J., Zhang, Y., Tang, C., Hou, Y., Ai, X., Chen, X., Zhang, Y., Wang, X., & Meng, X. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110985 · Cited by 720 · see citing works
Antibiotics and the Gut Microbiota
Modi, S. R., Collins, J. J., & Relman, D. A. (2014) · Journal of Clinical Investigation · doi:10.1172/jci72333 · Cited by 667 · see citing works
Flagged first, then by citations
Research works printed but not linked: 74
- Ahiwe E.U. Abdallh M.E. Chang'a E.P. Al-Qahtani M. Omede A.A. Graham H. Iji P.A. Influence of autolyzed whole yeast and yeast components on broiler chickens challenged with Salmonella lipopolysaccharide Poult. Sci. 98 2019 7129 7138 31392341 PMC6870557
- Ahmadipour B. Hassanpour H. Khajali F. Evaluation of hepatic lipogenesis and antioxidant status of broiler chickens fed mountain celery BMC Vet. Res. 14 2018 234 30103743 PMC6088407
- Ajuwon O.R. Oguntibeju O.O. Marnewick J.L. Amelioration of lipopolysaccharide-induced liver injury by aqueous rooibos (Aspalathus linearis) extract via inhibition of pro-inflammatory cytokines and oxidative stress BMC Complement. Altern. Med. 14 2014 392 25312795 PMC4201726
- Amir Aslani B. Ghobadi S. Studies on oxidants and antioxidants with a brief glance at their relevance to the immune system Life Sci. 146 2016 163 173 26792059
- Ansari A.R. Li N.Y. Sun Z.J. Huang H.B. Zhao X. Cui L. Hu Y.F. Zhong J.M. Karrow N.A. Liu H.Z. Lipopolysaccharide induces acute bursal atrophy in broiler chicks by activating TLR4-MAPK-NF-κB/AP-1 signaling Oncotarget 8 2017 108375 108391 29312537 PMC5752450
- Bendich A. Physiological role of antioxidants in the immune system J. Dairy Sci. 76 1993 2789 2794 8227682
- Bi W. Zhang J. Zeng Z. Zhou R. Zhao J. Yan W. Wang L. Li X. Zhu L. Ubiquitin‑specific protease 8 ameliorates lipopolysaccharide‑induced spleen injury via suppression of NF‑κB and MAPK signaling pathways Mol. Med. Rep. 26 2022 370 36321796 PMC9644427
- Candelli M. Franza L. Pignataro G. Ojetti V. Covino M. Piccioni A. Gasbarrini A. Franceschi F. Interaction between lipopolysaccharide and gut microbiota in inflammatory bowel diseases Int. J. Mol. Sci. 22 2021 6242 34200555 PMC8226948
- Caporaso J.G. Kuczynski J. Stombaugh J. Bittinger K. Bushman F.D. Costello E.K. Fierer N. Peña A.G. Goodrich J.K. Gordon J.I. Huttley G.A. Kelley S.T. Knights D. Koenig J.E. Ley R.E. Lozupone C.A. McDonald D. Muegge B.D. Pirrung M. Reeder J. Sevinsky J.R. Turnbaugh P.J. Walters W.A. Widmann J. Yatsunenko T. Zaneveld J. Knight R. QIIME allows analysis of high-throughput community sequencing data Nat. Methods 7 2010 335 336 20383131 PMC3156573
- Carullo G. Cappello A.R. Frattaruolo L. Badolato M. Armentano B. Aiello F. Quercetin and derivatives: useful tools in inflammation and pain management Future Med. Chem. 9 2017 79 93 27995808
- Carvalho J.T.G. Da Silva Baldivia D. Castro D.T.H. Santos H.F. Santos C.M. Oliveira A.S. Alfredo T.M. Vilharva K.N. de Picoli Souza K. dos Santos E.L. The immunoregulatory function of polyphenols: implications in cancer immunity J. Nutr. Biochem. 85 2020 108428 32679443
- Chasiotis H. Kolosov D. Bui P. Kelly S.P. Tight junctions, tight junction proteins and paracellular permeability across the gill epithelium of fishes: a review Respir. Physiol. Neurobiol. 184 2012 269 281 22640933
- Chen Y. Chen Y. Zhang H. Wang T. Pterostilbene as a protective antioxidant attenuates diquat-induced liver injury and oxidative stress in 21-day-old broiler chickens Poult. Sci. 99 2020 3158 3167 32475452 PMC7597657
- Chiu H.-F. Venkatakrishnan K. Golovinskaia O. Wang C.-K. Gastroprotective effects of polyphenols against various gastro-intestinal disorders: a mini-review with special focus on clinical evidence Molecules 26 2021 PMC8038706 33917379
- Cole J.R. Wang Q. Cardenas E. Fish J. Chai B. Farris R.J. Kulam-Syed-Mohideen A.S. McGarrell D.M. Marsh T. Garrity G.M. Tiedje J.M. The Ribosomal Database Project: improved alignments and new tools for rRNA analysis Nucleic Acids Res. 37 2009 D141 D145 19004872 PMC2686447
- de Mello Andrade J.M. Fasolo D. Chapter 20: Polyphenol antioxidants from natural sources and contribution to health promotion Watson R.R. Preedy V.R. Zibadi S. Polyphenols in Human Health and Disease 2014 Academic Press Washington, DC 253 265
- Fan Y. Lin F. Zhang R. Wang M. Gu R. Long C. Acer truncatum Bunge: a comprehensive review on ethnobotany, phytochemistry and pharmacology J. Ethnopharmacol. 282 2022 114572 34487848
- Farahat M.H. Abdallah F.M. Ali H.A. Hernandez-Santana A. Effect of dietary supplementation of grape seed extract on the growth performance, lipid profile, antioxidant status and immune response of broiler chickens Animal 11 2017 771 777 27804907
- Hirata T. Kizuka Y. N-glycosylation Adv. Exp. Med. Biol. 1325 2021 3 24 34495528
- Hu R. He Z. Liu M. Tan J. Zhang H. Hou D.-X. He J. Wu S. Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets J. Anim. Sci. Biotechnol. 11 2020 92 32944233 PMC7487840
- Hu R. Lin H. Wang M. Zhao Y. Liu H. Min Y. Yang X. Gao Y. Yang M. Lactobacillus reuteri-derived extracellular vesicles maintain intestinal immune homeostasis against lipopolysaccharide-induced inflammatory responses in broilers J. Anim. Sci. Biotechnol. 12 2021 25 33593426 PMC7888134
- Iyer S.S. Cheng G. Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease Crit. Rev. Immunol. 32 2012 23 63 22428854 PMC3410706
- Khadim R.M. Al-Fartusie F.S. Antioxidant vitamins and their effect on immune system J. Phys. Conf. Ser. 1853 2021 012065
- Kong L. Wang Z. Xiao C. Zhu Q. Song Z. Glycerol monolaurate attenuated immunological stress and intestinal mucosal injury by regulating the gut microbiota and activating AMPK/Nrf2 signaling pathway in lipopolysaccharide-challenged broilers Anim. Nutr. 10 2022 347 359 35919246 PMC9307562
- Li G. Zhao Y. Purswell J.L. Magee C. Effects of feeder space on broiler feeding behaviors Poult. Sci. 100 2021 101016 PMC7930638 33662663
- Li H. Christman L.M. Li R. Gu L. Synergic interactions between polyphenols and gut microbiota in mitigating inflammatory bowel diseases Food Funct. 11 2020 4878 4891 32490857
- Liu J. The Effect of Acer Truncatum on Growth Performance and Antioxidant Capacity Intestinal Flora of Weaned Piglets [Master Thesis] 2021 Northwest A&F University]
- Liu T. Zhang L. Joo D. Sun S.-C. NF-κB signaling in inflammation Signal Transduct. Target. Ther. 2 2017 17023 29158945 PMC5661633
- Mehrabadi M.H.F. Ghalyanchilangeroudi A. Tehrani F. Hajloo S.A. Bashashati M. Bahonar A.R. Pourjafar H. Ansari F. Assessing the economic burden of multi-causal respiratory diseases in broiler farms in Iran Trop. Anim. Health Prod. 54 2022 117 35224709
- Morita K. Tsukita S. Miyachi Y. Tight junction-associated proteins (occludin, ZO-1, claudin-1, claudin-4) in squamous cell carcinoma and Bowen's disease Br. J. Dermatol. 151 2004 328 334 15327539
- Morrison D.J. Preston T. Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism Gut. Microbes. 7 2016 189 200 26963409 PMC4939913
- National Research Council Nutrient Requirements of Poultry 9th rev. ed. 1994 Natl. Acad. Press Washington, DC
- Niu J.L. Wei L.Q. Luo Y.Q. Yang W.T. Lu Q.C. Zheng X.X. Niu Y.J. Sheng W. Cheng H. Zhang W.J. Nie C.X. Fermented cottonseed meal improves production performance and reduces fat deposition in broiler chickens Anim. Biosci. 34 2021 680 691 33254361 PMC7961297
- Presley L.L. Wei B. Braun J. Borneman J. Bacteria associated with immunoregulatory cells in mice Appl. Environ. Microbiol. 76 2010 936 941 20008175 PMC2813032
- Puertollano M.A. Puertollano E. de Cienfuegos G. de Pablo M.A. Dietary antioxidants: immunity and host defense Curr. Top Med. Chem. 11 2011 1752 1766 21506934
- Raederstorff D. Antioxidant activity of olive polyphenols in humans: a review Int. J. Vitam. Nutr. Res. 79 2009 152 165 20209466
- Ravindran V. Abdollahi M.R. Nutrition and digestive physiology of the broiler chick: state of the art and outlook Animals 11 2021 2795 34679817 PMC8532940
- Robertson R.C. Seira Oriach C. Murphy K. Moloney G.M. Cryan J.F. Dinan T.G. Ross R.P. Stanton C. Deficiency of essential dietary n-3 PUFA disrupts the caecal microbiome and metabolome in mice Br. J. Nutr. 118 2017 959 970 29173237
- Rodríguez-Daza M.C. Pulido-Mateos E.C. Lupien-Meilleur J. Guyonnet D. Desjardins Y. Roy D. Polyphenol-mediated gut microbiota modulation: toward prebiotics and further Front. Nutr. 8 2021 PMC8276758 34268328
- Rowland I. Gibson G. Heinken A. Scott K. Swann J. Thiele I. Tuohy K. Gut microbiota functions: metabolism of nutrients and other food components Eur. J. Nutr. 57 2018 1 24 PMC5847071 28393285
- Sanjay S. Girish C. Toi P.C. Bobby Z. Gallic acid attenuates isoniazid and rifampicin-induced liver injury by improving hepatic redox homeostasis through influence on Nrf2 and NF-κB signalling cascades in Wistar Rats J. Pharm. Pharmacol. 73 2021 473 486 33793834
- Schulze Bernd K. Wilms-Schulze Kump A. Rohn K. Reich F. Kehrenberg C. Management factors influencing the occurrence of cellulitis in broiler chickens Prev. Vet. Med. 183 2020 105146 32927303
- Shen L. Zhou Y. Wu X. Sun Y. Xiao T. Gao Y. Wang J. TREM1 blockade ameliorates lipopolysaccharide-induced acute intestinal dysfunction through inhibiting intestinal apoptosis and inflammation response Biomed. Res. Int. 2021 2021 6635452 PMC8068534 33954188
- Shreiner A.B. Kao J.Y. Young V.B. The gut microbiome in health and in disease Curr. Opin. Gastroenterol. 31 2015 PMC4290017 25394236
- Silvestre G.F.G. de Lucena R.P. da Silva Alves H. Cucurbitacins and the immune system: update in research on anti-inflammatory, antioxidant, and immunomodulatory mechanisms Curr. Med. Chem. 29 2022 3774 3789 34994307
- Sivaprakasam S. Prasad P.D. Singh N. Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis Pharmacol. Ther. 164 2016 144 151 27113407 PMC4942363
- Slimestad R. Fossen T. Vågen I.M. Onions: a source of unique dietary flavonoids J. Agric. Food Chem. 55 2007 10067 10080 17997520
- Song B. Tang D. Yan S. Fan H. Li G. Shahid M.S. Mahmood T. Guo Y. Effects of age on immune function in broiler chickens J. Anim. Sci. Biotechnol. 12 2021 42 33731181 PMC7971956
- Song J. Li Q. Everaert N. Liu R. Zheng M. Zhao G. Wen J. Dietary inulin supplementation modulates short-chain fatty acid levels and cecum microbiota composition and function in chickens infected with Salmonella Front. Microbiol. 11 2020 PMC7793945 33424783
- Sugiharto S. Ranjitkar S. Recent advances in fermented feeds towards improved broiler chicken performance, gastrointestinal tract microecology and immune responses: a review Anim. Nutr. 5 2019 1 10 30899804 PMC6407077
- Tan J. McKenzie C. Potamitis M. Thorburn A.N. Mackay C.R. Macia L. Chapter 3: The role of short-chain fatty acids in health and disease Alt F.W. Pages 91–119 in Advances in Immunology (121) 2014 Academic Press 24388214
- Tanaka T. Narazaki M. Kishimoto T. IL-6 in inflammation, immunity, and disease Cold Spring Harb. Perspect. Biol. 6 2014 a016295 PMC4176007 25190079
- Tian S. Wang J. Gao R. Wang J. Zhu W. Early-life galacto-oligosaccharides supplementation alleviates the small intestinal oxidative stress and dysfunction of lipopolysaccharide-challenged suckling piglets J. Anim. Sci. Biotechnol. 13 2022 70 35655292 PMC9164537
- Wang P. Li D. Ke W. Liang D. Hu X. Chen F. Resveratrol-induced gut microbiota reduces obesity in high-fat diet-fed mice Int. J. Obes. 44 2020 213 225 30718820
- Wang Q. Jin L. Wang H. Tai S. Liu H. Zhang D. AWRK6, a synthetic cationic peptide derived from antimicrobial peptide dybowskin-2CDYa, inhibits lipopolysaccharide-induced inflammatory response Int. J. Mol. Sci. 19 2018 600 29463000 PMC5855822
- Wang S. Li Z. Ma Y. Liu Y. Lin C.-C. Li S. Zhan J. Ho C.-T. Immunomodulatory effects of green tea polyphenols Molecules 26 2021 3755 34203004 PMC8234133
- Xie Y. Wen M. Zhao H. Liu G. Chen X. Tian G. Cai J. Jia G. Effect of zinc supplementation on growth performance, intestinal development, and intestinal barrier function in Pekin ducks with lipopolysaccharide challenge Poult. Sci. 100 2021 101462 PMC8567444 34731734
- Xu B. Zhu L. Fu J. Li Z. Wang Y. Jin M. Overall assessment of fermented feed for pigs: a series of meta-analyses J. Anim. Sci. 97 2019 4810 4821 31712812 PMC6915212
- Xu X. Hua H. Wang L. He P. Zhang L. Qin Q. Yu C. Wang X. Zhang G. Liu Y. Holly polyphenols alleviate intestinal inflammation and alter microbiota composition in lipopolysaccharide-challenged pigs Br. J. Nutr. 123 2020 881 891 31928547
- Yahfoufi N. Alsadi N. Jambi M. Matar C. The immunomodulatory and anti-inflammatory role of polyphenols Nutrients 10 2018 PMC6266803 30400131
- Yang L. Evaluation of Phenolic Compounds in Acer Truncatum Leaves and Characterizations of Its Flavonoids Biosynthesis Pathway [Doctor Dissertation] 2019 Beijing Forestry University]
- Yang L. Liu G. Zhu X. Luo Y. Shang Y. Gu X.-L. The anti-inflammatory and antioxidant effects of leonurine hydrochloride after lipopolysaccharide challenge in broiler chicks Poult. Sci. 98 2019 1648 1657 30476291
- Yang L. Yin P. Fan H. Xue Q. Li K. Li X. Sun L. Liu Y. Response surface methodology optimization of ultrasonic-assisted extraction of Acer truncatum leaves for maximal phenolic yield and antioxidant activity Molecules 22 2017 232 28165408 PMC6155778
- Yang L. Yin P. Ho C.T. Yu M. Sun L. Liu Y. Effects of thermal treatments on 10 major phenolics and their antioxidant contributions in Acer truncatum leaves and flowers R. Soc. Open. Sci. 5 2018 180364 PMC6030319 30110480
- Yang Q. Liang Q. Balakrishnan B. Belobrajdic D.P. Feng Q.-J. Zhang W. Role of dietary nutrients in the modulation of gut microbiota: a narrative review Nutrients 12 2020 381 32023943 PMC7071260
- Yang S. Zhang J. Jiang Y. Xu Y.Q. Jin X. Yan S.M. Shi B.l. Effects of Artemisia argyi flavonoids on growth performance and immune function in broilers challenged with lipopolysaccharide Anim. Biosci. 34 2021 1169 1180 33561921 PMC8255877
- Ye J. Zhang C. Fan Q. Lin X. Wang Y. Azzam M. Alhotan R. Alqhtani A. Jiang S. Antrodia cinnamomea polysaccharide improves liver antioxidant, anti-inflammatory capacity, and cecal flora structure of slow-growing broiler breeds challenged with lipopolysaccharide Front. Vet. Sci. 9 2022 PMC9588918 36299632
- Zhang H. Chen Y. Chen Y. Li Y. Jia P. Ji S. Zhou Y. Wang T. Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide J. Anim. Sci. 98 2019 PMC6986435 31822918
- Zhao W.H. Gao L.F. Gao W. Yuan Y.S. Gao C.C. Cao L.G. Hu Z.Z. Guo J.Q. Zhang Y.X. Weight-reducing effect of Acer truncatum Bunge may be related to the inhibition of fatty acid synthase Nat. Prod. Res. 25 2011 422 431 21328136
- Zhao W.H. Zhang J.F. Zhe-Wang Zhang Y.X. Tian W.X. The extract of leaves of Acer truncatum Bunge: A natural inhibitor of fatty acid synthase with antitumor activity J. Enzyme. Inhib. Med. Chem. 21 2006 589 596 17194032
- Zhao Y. Jiang Q. Roles of the polyphenol–gut microbiota interaction in alleviating colitis and preventing colitis-associated colorectal cancer Adv. Nutr. 12 2021 546 565 32905583 PMC8009754
- Zheng X.C. Wu Q.J. Song Z.H. Zhang H. Zhang J.F. Zhang L.L. Zhang T.Y. Wang C. Wang T. Effects of Oridonin on growth performance and oxidative stress in broilers challenged with lipopolysaccharide Poult. Sci. 95 2016 2281 2289 27143760
- Zhou H.J. Kong L.L. Zhu L.X. Hu X.Y. Busye J. Song Z.G. Effects of cold stress on growth performance, serum biochemistry, intestinal barrier molecules, and adenosine monophosphate-activated protein kinase in broilers Animal 15 2021 100138 33573943
- Zhou J. Tang L. Shen C.-L. Wang J.-S. Green tea polyphenols boost gut-microbiota-dependent mitochondrial TCA and urea cycles in Sprague–Dawley rats J. Nutr. Biochem. 81 2020 108395 32388254
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Wang, C., Liu, H., Zhang, S., Ren, C., Xu, J., Chen, J., Chen, H., & Wu, W. (2025) · Nutrients · doi:10.3390/nu17020355 · Cited by 7 · see citing works
- Authors
- Liu, J., Liang, S., Qin, K., Jia, B., Ren, Z., Yang, X., & Yang, X.
- Venue
- Poultry Science
- Publisher
- Elsevier BV
- Published
- 2023-10
- Volume
- 102
- Issue
- 10
- Pages
- 102951
- ISSN
- 0032-5791
- PMC
- PMC10432845
- Cited by
- 17
- References
- 6
- Language
- en
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