Gallic acid: pharmacological activities and molecular mechanisms involved in inflammation-related diseases

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Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: Involvement of the Nrf2/HO-1 signaling and anti-apoptosis role

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The Role of Butyrate in Attenuating Pathobiont-Induced Hyperinflammation

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Gallic acid suppresses inflammation in dextran sodium sulfate-induced colitis in mice: Possible mechanisms

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Anti-metastasis effects of gallic acid on gastric cancer cells involves inhibition of NF-κB activity and downregulation of PI3K/AKT/small GTPase signals

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Gallic Acid Suppresses Lipopolysaccharide-Induced Nuclear Factor-κB Signaling by Preventing RelA Acetylation in A549 Lung Cancer Cells

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Resveratrol supplement inhibited the NF-κB inflammation pathway through activating AMPKα-SIRT1 pathway in mice with fatty liver

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Inhibition of Melanogenesis by Gallic Acid: Possible Involvement of the PI3K/Akt, MEK/ERK and Wnt/β-Catenin Signaling Pathways in B16F10 Cells

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Gallic acid, a histone acetyltransferase inhibitor, suppresses β‐amyloid neurotoxicity by inhibiting microglial‐mediated neuroinflammation

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Anti-inflammatory and ameliorative effects of gallic acid on fluoxetine-induced oxidative stress and liver damage in rats

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Gallic acid, a natural polyphenolic acid, induces apoptosis and inhibits proinflammatory gene expressions in rheumatoid arthritis fibroblast-like synoviocytes

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Gallic acid improved inflammation via NF-κB pathway in TNBS-induced ulcerative colitis.

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Mechanisms of NLRP3 priming in inflammaging and age related diseases

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Gallic acid indanone and mangiferin xanthone are strong determinants of immunosuppressive anti-tumour effects of Mangifera indica L. bark in MDA-MB231 breast cancer cells

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Anti-Inflammatory Activities of Pentaherbs Formula, Berberine, Gallic Acid and Chlorogenic Acid in Atopic Dermatitis-Like Skin Inflammation

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Gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BALB/c mice

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Toona sinensis and its major bioactive compound gallic acid inhibit LPS-induced inflammation in nuclear factor-κB transgenic mice as evaluated by in vivo bioluminescence imaging

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SIRT1/Adenosine Monophosphate-Activated Protein Kinase α Signaling Enhances Macrophage Polarization to an Anti-inflammatory Phenotype in Rheumatoid Arthritis

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Gallic Acid Attenuated LPS-Induced Neuroinflammation: Protein Aggregation and Necroptosis

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Gallic acid exerts anti-inflammatory, anti-oxidative stress, and nephroprotective effects against paraquat-induced renal injury in male rats

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Gallic acid decreases hepatitis C virus expression through its antioxidant capacity

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Chebulagic acid Chebulinic acid and Gallic acid, the active principles of Triphala, inhibit TNFα induced pro-angiogenic and pro-inflammatory activities in retinal capillary endothelial cells by inhibiting p38, ERK and NFkB phosphorylation

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Acute and 28-days repeated dose sub-acute toxicity study of gallic acid in albino mice

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Mitochondrial MPTP: A Novel Target of Ethnomedicine for Stroke Treatment by Apoptosis Inhibition

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Gallic acid inhibits gastric cancer cells metastasis and invasive growth via increased expression of RhoB, downregulation of AKT/small GTPase signals and inhibition of NF-κB activity

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Gallic Acid Inhibits Lipid Accumulation via AMPK Pathway and Suppresses Apoptosis and Macrophage-Mediated Inflammation in Hepatocytes

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Gallic acid alleviates nasal inflammation via activation of Th1 and inhibition of Th2 and Th17 in a mouse model of allergic rhinitis

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A comprehensive study of pomegranate flowers polyphenols and metabolites in rat biological samples by high-performance liquid chromatography quadrupole time-of-flight mass spectrometry

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Cinnamaldehyde suppresses NLRP3 derived IL-1β via activating succinate/HIF-1 in rheumatoid arthritis rats.

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Identification and analysis of MKK and MPK gene families in canola (Brassica napusL.)

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Post-Stroke Depression Modulation and in Vivo Antioxidant Activity of Gallic Acid and Its Synthetic Derivatives in a Murine Model System

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Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway

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Antibiotic therapy for pelvic inflammatory disease

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Antiviral Effects of Black Raspberry (Rubus coreanus) Seed and Its Gallic Acid against Influenza Virus Infection

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p53 predominantly regulates IL-6 production and suppresses synovial inflammation in fibroblast-like synoviocytes and adjuvant-induced arthritis

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Gallic acid reduces cell growth by induction of apoptosis and reduction of IL-8 in HepG2 cells

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Improved Neuroprotective Effects of Gallic Acid-Loaded Chitosan Nanoparticles Against Ischemic Stroke

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Protective effect of gallic acid and gallic acid-loaded Eudragit-RS 100 nanoparticles on cisplatin-induced mitochondrial dysfunction and inflammation in rat kidney

Dehghani, M. A., Maram, N. S., Moghimipour, E., Khorsandi, L., khah, M. A., & Mahdavinia, M. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2020.165911 · Cited by 68 · see citing works

Inhibitory effects of Lentinus edodes mycelia polysaccharide on α-glucosidase, glycation activity and high glucose-induced cell damage

Cao, X., Xia, Y., Liu, D., He, Y., Mu, T., Huo, Y., & Liu, J. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.116659 · Cited by 67 · see citing works

Anti-inflammatory Effect of Methyl Gallate on Experimental Arthritis: Inhibition of Neutrophil Recruitment, Production of Inflammatory Mediators, and Activation of Macrophages

Corrêa, L. B., Pádua, T. A., Seito, L. N., Costa, T. E. M. M., Silva, M. A., Candéa, A. L. P., Rosas, E. C., & Henriques, M. D. G. (2016) · Journal of Natural Products · doi:10.1021/acs.jnatprod.5b01115 · Cited by 66 · see citing works

Antibiotic therapy for pelvic inflammatory disease

Savaris, R. F., Fuhrich, D. G., Duarte, R. V., Franik, S., & Ross, J. D. C. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010285.pub2 · Cited by 66 · see citing works

Simultaneous determination of fourteen compounds of Hedyotis diffusa Willd extract in rats by UHPLC–MS/MS method: Application to pharmacokinetics and tissue distribution study

Chen, X., Zhu, P., Liu, B., Wei, L., & Xu, Y. (2018) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2018.07.023 · Cited by 64 · see citing works

The effects of synbiotic supplementation on thyroid function and inflammation in hypothyroid patients: a randomized, double-blind, placebo-controlled trial

Talebi, S., Karimifar, M., Heidari, Z., Mohammadi, H., & Askari, G. (2020) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2019.102234 · Cited by 64 · see citing works

Modulation of cell signaling pathways by Phyllanthus amarus and its major constituents: potential role in the prevention and treatment of inflammation and cancer

Harikrishnan, H., Jantan, I., Alagan, A., & Haque, M. A. (2019) · Inflammopharmacology · doi:10.1007/s10787-019-00671-9 · Cited by 64 · see citing works

Paeonol protects against TNF-α-induced proliferation and cytokine release of rheumatoid arthritis fibroblast-like synoviocytes by upregulating FOXO3 through inhibition of miR-155 expression

Liu, N., Feng, X., Wang, W., Zhao, X., & Li, X. (2017) · Inflammation Research · doi:10.1007/s00011-017-1041-7 · Cited by 63 · see citing works

Metabolite profiling of polyphenols in a Terminalia chebula Retzius ayurvedic decoction and evaluation of its chemopreventive activity

Pellati, F., Bruni, R., Righi, D., Grandini, A., Tognolini, M., Prencipe, F. P., Poli, F., Benvenuti, S., Rio, D. D., & Rossi, D. (2013) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2013.02.025 · Cited by 62 · see citing works

Phenolic Profile and Antioxidant Activity of the Edible Tree Peony Flower and Underlying Mechanisms of Preventive Effect on H2O2-Induced Oxidative Damage in Caco-2 Cells

Xiang, J., Yang, C., Trust Beta, Liu, S., & Yang, R. (2019) · Foods · doi:10.3390/foods8100471 · Cited by 61 · see citing works

Anti-Inflammatory and Anti-Allergic Activities of Pentaherb Formula, Moutan Cortex (Danpi) and Gallic Acid

Liu, K., Hu, S., Chan, B. C.-L., Wat, E., Lau, C. B., Hon, K. E., Fung, K., Leung, P., Hui, C. L., Lam, C. W. K., et al. (2013) · Molecules · doi:10.3390/molecules18032483 · Cited by 60 · see citing works

Gallic acid protects against the COPD-linked lung inflammation and emphysema in mice

Singla, E., Dharwal, V., & Naura, A. S. (2020) · Inflammation Research · doi:10.1007/s00011-020-01333-1 · Cited by 60 · see citing works

Mutamba (Guazuma ulmifolia Lam.) fruit as a novel source of dietary fibre and phenolic compounds

Pereira, G. A., Arruda, H. S., de Morais, D. R., Araújo, N. M. P., & Pastore, G. M. (2019) · Food Chemistry · doi:10.1016/j.foodchem.2019.125857 · Cited by 58 · see citing works

Potential applications of microfluidics based blood brain barrier (BBB)-on-chips for in vitro drug development

Wang, X., Hou, Y., Ai, X., Sun, J., Xu, B., Meng, X., Zhang, Y., & Zhang, S. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110822 · Cited by 58 · see citing works

Early toll‐like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro‐inflammatory phenotype in rodent and human brain ischaemia models

Parada, E., Casas, A. I., Palomino‐Antolín, A., Gómez‐Rangel, V., Rubio‐Navarro, A., Farré‐Alins, V., Narros‐Fernández, P., Guerrero‐Hue, M., Moreno, J. A., Rosa, J. M., et al. (2019) · British Journal of Pharmacology · doi:10.1111/bph.14703 · Cited by 57 · see citing works

A UHPLC–MS/MS method for simultaneous determination of six flavonoids, gallic acid and 5,8-dihydroxy-1,4-naphthoquinone in rat plasma and its application to a pharmacokinetic study of Cortex Juglandis Mandshuricae extract

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Comparative analysis of plant MKK gene family reveals novel expansion mechanism of the members and sheds new light on functional conservation

Jiang, M., & Chu, Z. (2018) · BMC Genomics · doi:10.1186/s12864-018-4793-8 · Cited by 54 · see citing works

Treatment with NAD + inhibited experimental autoimmune encephalomyelitis by activating AMPK/SIRT1 signaling pathway and modulating Th1/Th17 immune responses in mice

Wang, J., Zhao, C., Kong, P., Sun, H., Sun, Z., Bian, G., Sun, Y., & Guo, L. (2016) · International Immunopharmacology · doi:10.1016/j.intimp.2016.07.036 · Cited by 52 · see citing works

Antioxidant and Anti-Inflammatory Activities of the Crude Extracts of Raw and Fermented Tomato Pomace and Their Correlations with Aglycate-Polyphenols

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An UHPLC–MS/MS method for simultaneous quantification of gallic acid and protocatechuic acid in rat plasma after oral administration of Polygonum capitatum extract and its application to pharmacokinetics

Ma, F., Gong, X., Zhou, X., Zhao, Y., & Li, M. (2014) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2014.12.044 · Cited by 50 · see citing works

Antioxidant potential and phenolic acid content of certain cucurbitaceous plants cultivated in Egypt

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Gallic Acid Attenuates Platelet Activation and Platelet-Leukocyte Aggregation: Involving Pathways of Akt and GSK3β

Chang, S., Lee, V. S. Y., Tseng, Y.-L., Chang, K., Chen, K., Chen, Y., & Li, C. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/683872 · Cited by 50 · see citing works

The enzymatic poly(gallic acid) reduces pro-inflammatory cytokines in vitro, a potential application in inflammatory diseases

Zamudio-Cuevas, Y. E., Andonegui-Elguera, M. A., Aparicio‐Juárez, A., Aguillón-Solís, E., Martínez‐Flores, K., Ruvalcaba-Paredes, E. K., Velasquillo, C., Ibarra, C., Martínez-López, V., Gutiérrez, M., et al. (2020) · Inflammation · doi:10.1007/s10753-020-01319-5 · Cited by 50 · see citing works

Rhodiola Crenulata ameliorates exhaustive exercise‑induced fatigue in mice by suppressing mitophagy in skeletal muscle

Hou, Y., Tang, Y., Wang, X., Ai, X., Wang, H., Li, X., Chen, X., Zhang, Y., Hu, Y., Meng, X., et al. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.9072 · Cited by 49 · see citing works

Epigenetic reprogramming reverses the malignant epigenotype of the MMP/TIMP axis genes in tumor cells

Zhang, S., Zhong, B., Chen, M., Li, Y., Yang, G., Li, Y., Wang, H., Wang, G., Li, W., Cui, J., et al. (2013) · International Journal of Cancer · doi:10.1002/ijc.28487 · Cited by 48 · see citing works

Gallic acid reduces the effect of LPS on apoptosis and inhibits the formation of neutrophil extracellular traps

Haute, G. V., Caberlon, E., Squizani, E. D., de Mesquita, F. C., Pedrazza, L., Martha, B. A., Melo, D. A. D. S., Cassel, E., Czepielewski, R. S., Bitencourt, S., et al. (2015) · Toxicology in Vitro · doi:10.1016/j.tiv.2015.10.005 · Cited by 48 · see citing works

OsMKK3, a Stress-Responsive Protein Kinase, Positively Regulates Rice Resistance to Nilaparvata lugens via Phytohormone Dynamics

Zhou, S., Chen, M., Zhang, Y., Gao, Q., Noman, A., Wang, Q., Li, H., Chen, L., Zhou, P., Lu, J., et al. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20123023 · Cited by 48 · see citing works

Hepatoprotective efficacy of gallic acid during Nitrosodiethylamine-induced liver inflammation in Wistar rats

Latief, U., Husain, H., Mukherjee, D., & Ahmad, R. (2016) · The Journal of Basic and Applied Zoology · doi:10.1016/j.jobaz.2016.07.002 · Cited by 47 · see citing works

Longzhibu disease and its therapeutic effects by traditional Tibetan medicine: Ershi-wei Chenxiang pills

Hou, Y., Qieni, X.-M., Li, N., Bai, J., Li, R., Gongbao, D.-Z., Liang, Y., Fan, F., Wencheng, D.-Z., Wang, Z., et al. (2019) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2019.112426 · Cited by 47 · see citing works

Wild Italian Prunus spinosa L. Fruit Exerts In Vitro Antimicrobial Activity and Protects Against In Vitro and In Vivo Oxidative Stress

Pozzo, L., Russo, R., Frassinetti, S., Vizzarri, F., Árvay, J., Vornoli, A., CASAMASSIMA, D., Palazzo, M., Croce, C. M. D., & Longo, V. G. (2019) · Foods · doi:10.3390/foods9010005 · Cited by 47 · see citing works

Are Supplements Safe? Effects of Gallic and Ferulic Acids on In Vitro Cell Models

Truzzi, F., Valerii, M. C., Tibaldi, C., Zhang, Y., Вадимовна, А. В., Spisni, E., & Dinelli, G. (2020) · Nutrients · doi:10.3390/nu12061591 · Cited by 47 · see citing works

Diet with high content of advanced glycation end products induces systemic inflammation and weight gain in experimental mice: Protective role of curcumin and gallic acid

Rajan, B. S., Manivasagam, S., Dhanusu, S., Chandrasekar, N., Krishna, K., Kalaiarasu, L. P., Babu, A. A., & Vellaichamy, E. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.02.016 · Cited by 46 · see citing works

Magnoflorine Enhances LPS-Activated Pro-Inflammatory Responses via MyD88-Dependent Pathways in U937 Macrophages

Haque, M. A., Jantan, I., Harikrishnan, H., & Wahab, S. M. A. (2018) · Planta Medica · doi:10.1055/a-0637-9936 · Cited by 45 · see citing works

Phenolic Composition of Hydrophilic Extract of Manna from Sicilian Fraxinus angustifolia Vahl and its Reducing, Antioxidant and Anti-Inflammatory Activity in Vitro

Attanzio, A., D’Anneo, A., Pappalardo, F., Bonina, F. P., Livrea, M. A., Allegra, M., & Tesoriere, L. (2019) · Antioxidants · doi:10.3390/antiox8100494 · Cited by 45 · see citing works

Cinnamic Aldehyde Inhibits Lipopolysaccharide-Induced Chondrocyte Inflammation and Reduces Cartilage Degeneration by Blocking the Nuclear Factor-Kappa B Signaling Pathway

Chen, P., Ruan, A., Zhou, J., Huang, L., Zhang, X., Ma, Y.-F., & Wang, Q.-F. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00949 · Cited by 41 · see citing works

Gallic acid protects against ethanol-induced hepatocyte necroptosis via an NRF2-dependent mechanism.

Zhou, Y., Jin, H., Wu, Y., Chen, L., Bao, X.-F., & Lu, C.-F. (2019) · Toxicology in Vitro · doi:10.1016/j.tiv.2019.03.008 · Cited by 40 · see citing works

MyD88 Regulates LPS-induced NF-ĸB/MAPK Cytokines and Promotes Inflammation and Malignancy in Colorectal Cancer Cells

Zhu, G., Cheng, Z., Lin, C., Hoffman, R. M., Huang, Y., Singh, S. R., ZHENG, W., Yang, S., & Ye, J. (2019) · Cancer Genomics & Proteomics · doi:10.21873/cgp.20145 · Cited by 40 · see citing works

Polyphenols in Barringtonia racemosa and their protection against oxidation of LDL, serum and haemoglobin

Kong, K. W., Junit, S. M., Ismail, A., Aminudin, N., & Aziz, A. A. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2013.09.012 · Cited by 39 · see citing works

Gallic acid attenuates chromium-induced thyroid dysfunction by modulating antioxidant status and inflammatory cytokines

Mohamed, H. M., & El-Twab, S. M. A. (2016) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2016.08.019 · Cited by 37 · see citing works

ATP-driven and AMPK-independent autophagy in an early branching eukaryotic parasite

Li, F., Xu, Z.-S., Soo, A. D. S., Lun, Z., & He, C. Y. (2017) · Autophagy · doi:10.1080/15548627.2017.1280218 · Cited by 37 · see citing works

Impact of genetic variations in the MAPK signaling pathway on outcome in metastatic colorectal cancer patients treated with first-line FOLFIRI and bevacizumab: data from FIRE-3 and TRIBE trials

Berger, M. D., Stintzing, S., Heinemann, V., Yang, D., Cao, S., Sunakawa, Y., Ning, Y., Matsusaka, S., Okazaki, S., Miyamoto, Y., et al. (2017) · Annals of Oncology · doi:10.1093/annonc/mdx412 · Cited by 37 · see citing works

Secreted Factors from Adipose Tissue Reprogram Tumor Lipid Metabolism and Induce Motility by Modulating PPARα/ANGPTL4 and FAK

Blücher, C., Iberl, S., Schwagarus, N., Müller, S., Liebisch, G., Höring, M., Hidrobo, M. S., Ecker, J., Spindler, N., Dietrich, A., et al. (2020) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-19-1223 · Cited by 37 · see citing works

Anti-inflammatory, antiallodynic effects and quantitative analysis of gallic acid in spray dried powders from Phyllanthus niruri leaves, stems, roots and whole plant

Couto, A. G., Kassuya, C. A. L., Calixto, J. Β., & Petrovick, P. R. (2013) · Revista Brasileira de Farmacognosia · doi:10.1590/s0102-695x2013000100017 · Cited by 37 · see citing works

Phenolic acid and flavonoid production in agar, agitated and bioreactor-grown microshoot cultures of Schisandra chinensis cv. Sadova No. 1 – a valuable medicinal plant

Szopa, A., Klimek-Szczykutowicz, M., Kokotkiewicz, A., Dziurka, M., Łuczkiewicz, M., & Ekiert, H. (2019) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2019.08.021 · Cited by 36 · see citing works

Gallic acid prevents 1, 2‐Dimethylhydrazine induced colon inflammation, toxicity, mucin depletion, and goblet cell disintegration

Shree, A., Islam, J., Vafa, A., Afzal, S. M., & Sultana, S. (2020) · Environmental Toxicology · doi:10.1002/tox.22900 · Cited by 36 · see citing works

Anti-inflammatory, antiallodynic effects and quantitative analysis of gallic acid in spray dried powders from Phyllanthus niruri leaves, stems, roots and whole plant

Couto, A. G., Kassuya, C. A. L., Calixto, J. Β., & Petrovick, P. R. (2012) · Revista Brasileira de Farmacognosia · doi:10.1590/s0102-695x2012005000133 · Cited by 35 · see citing works

Glycogen Metabolism and Rheumatoid Arthritis: The Role of Glycogen Synthase 1 in Regulation of Synovial Inflammation via Blocking AMP-Activated Protein Kinase Activation

Shi, M., Wang, J., Xiao, Y., Wang, C., Qiu, Q., Lao, M., Yu, Y., Li, Z., Zhang, H., Ye, Y., et al. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.01714 · Cited by 35 · see citing works

Gallic acid attenuates allergic airway inflammation via suppressed interleukin‐33 and group 2 innate lymphoid cells in ovalbumin‐induced asthma in mice

Wang, X., Zhao, H., Ma, C., Lv, L., Feng, J., & Han, S. (2018) · International Forum of Allergy & Rhinology · doi:10.1002/alr.22207 · Cited by 35 · see citing works

UHPLC–MS/MS method for the simultaneous quantitation of five anthraquinones and gallic acid in rat plasma after oral administration of prepared rhubarb decoction and its application to a pharmacokinetic study in normal and acute blood stasis rats

Zhu, H., Liu, X., Zhu, T., Wang, X. L., Qin, K. M., Pei, K., & Cai, B. (2017) · Journal of Separation Science · doi:10.1002/jssc.201700166 · Cited by 34 · see citing works

Nicotine-induced oxidative stress, testis injury, AChE inhibition and brain damage alleviated by Mentha spicata

Saad, A. B., Rjeibi, I., Brahmi, N., Elaloui, E., & Zouari, N. (2019) · Inflammopharmacology · doi:10.1007/s10787-019-00650-0 · Cited by 34 · see citing works

Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice

Yu, Y., Cui, S., Zheng, T.-N., Ma, H., Xie, Z., Jiang, H., Li, Y., Zhu, K., Huang, C., Li, J. X., et al. (2020) · Acta Pharmacologica Sinica · doi:10.1038/s41401-020-0427-1 · Cited by 34 · see citing works

A UPLC-MS/MS Method for Simultaneous Determination of Free and Total Forms of a Phenolic Acid and Two Flavonoids in Rat Plasma and Its Application to Comparative Pharmacokinetic Studies of Polygonum capitatum Extract in Rats

Huang, Y., Sun, H.-Y., Qin, X., Li, Y.-J., Liao, S., Gong, Z., Lü, Y., Wang, Y., Wang, A., Lan, Y., et al. (2017) · Molecules · doi:10.3390/molecules22030353 · Cited by 33 · see citing works

Subtle regulation of cotton resistance to Verticillium wilt mediated by MAPKK family members

Meng, J., Gao, H., Zhai, W., Shi, J., Zhang, M., Zhang, W., Jian, G., Zhang, M., & Qi, F. (2018) · Plant Science · doi:10.1016/j.plantsci.2018.05.003 · Cited by 33 · see citing works

Red-jambo peel extract shows antiproliferative activity against HepG2 human hepatoma cells

Vuolo, M. M., Batista, Â. G., Biasoto, A. C. T., Corrêa, L. C., Maróstica, M. R., & Liu, R. H. (2018) · Food Research International · doi:10.1016/j.foodres.2018.08.040 · Cited by 33 · see citing works

Carvacrol suppresses inflammatory responses in rheumatoid arthritis fibroblast‐like synoviocytes

Yu, L., Xu, J., Gu, C., Liu, G., & Tian, K. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.28098 · Cited by 33 · see citing works

Gallic acid prevents ketamine-induced oxidative damages in brain regions and liver of rats

Schimites, P. I., Segat, H. J., Teixeira, L. G., Martins, L. R., Mangini, L. T., Baccin, P. S., Rosa, H. Z., Milanesi, L. H., Bürger, M. E., & Soares, A. V. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134560 · Cited by 33 · see citing works

Phenolic Profile, Antioxidant Activity, and Anti-obesogenic Bioactivity of Mao Luang Fruits (Antidesma bunius L.)

Krongyut, O., & Sutthanut, K. (2019) · Molecules · doi:10.3390/molecules24224109 · Cited by 33 · see citing works

Comparative Pharmacokinetics of Gallic Acid After Oral Administration of Gallic Acid Monohydrate in Normal and Isoproterenol-Induced Myocardial Infarcted Rats

Yu, Z., Song, F., Jin, Y.-C., Zhang, W., Zhang, Y., Liu, E.-J., Zhou, D., Bi, L.-L., Yang, Q., Li, H., et al. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00328 · Cited by 32 · see citing works

Microfluidic chip and its application in autophagy detection

Wang, X., Liu, Z., Fan, F., Hou, Y., Yang, H., Meng, X., Zhang, Y., & Ren, F. (2019) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2019.05.043 · Cited by 32 · see citing works

Integrated identification, qualification and quantification strategy for pharmacokinetic profile study of Guizhi Fuling capsule in healthy volunteers

Zhong, Y., Jin, X., Gu, S., Peng, Y. H., Zhang, K.-R., Ouyang, B., Wang, Y., Xiao, W., Wang, Z., Aa, J., et al. (2016) · Scientific Reports · doi:10.1038/srep31364 · Cited by 30 · see citing works

HPLC–PDA Polyphenolic Quantification, UHPLC–MS Secondary Metabolite Composition, and In Vitro Enzyme Inhibition Potential of Bougainvillea glabra

Saleem, H., Htar, T. T., Naidu, R., Anwar, S., Zengin, G., Locatelli, M., & Ahemad, N. (2020) · Plants · doi:10.3390/plants9030388 · Cited by 29 · see citing works

Novel molecularly imprinted amoxicillin sensor based on a dual recognition and dual detection strategy

Li, S., Ma, X., Pang, C., Li, H., Liu, C., Xu, Z., Luo, J., & Yang, Y. (2020) · Analytica Chimica Acta · doi:10.1016/j.aca.2020.06.034 · Cited by 29 · see citing works

Identification on mitogen-activated protein kinase signaling cascades by integrating protein interaction with transcriptional profiling analysis in cotton

Zhang, X., Mi, X., Chen, C., Wang, H., & Guo, W. (2018) · Scientific Reports · doi:10.1038/s41598-018-26400-w · Cited by 27 · see citing works

Influence of gallic acid on porcine neutrophils phosphodiesterase 4, IL-6, TNF-α and rat arthritis model

JIANG, D.-X., Zhang, M., Zhang, Q., Yi-shan, C. H. E. N., Ma, W., Wei-peng, W. U., Mu, X., & Wu, C. H. E. N. (2015) · Journal of Integrative Agriculture · doi:10.1016/s2095-3119(14)60824-8 · Cited by 26 · see citing works

Gallic Acid‐L‐Leucine Conjugate Protects Mice against LPS‐Induced Inflammation and Sepsis via Correcting Proinflammatory Lipid Mediator Profiles and Oxidative Stress

Cheng, Y., Li, X., Tse, H., & Rong, J. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/1081287 · Cited by 26 · see citing works

Secondary plant substances in various extracts of the leaves, fruits, stem and bark of Caraipa densifolia Mart.

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Sorocea guilleminiana Gaudich.: Wound healing activity, action mechanisms, and chemical characterization of the leaf infusion

Figueiredo, F. D. F., Filho, V. C., Damazo, A. S., Arunachalam, K., Colodel, É. M., Ribeiro, M., Venturini, C. L., Oliveira, D. M., Machado, M. T. M., Pavan, E., et al. (2019) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2019.112307 · Cited by 25 · see citing works

Systematically explore the potential hepatotoxic material basis and molecular mechanism of Radix Aconiti Lateralis based on the concept of toxicological evidence chain (TEC)

Zhang, K., Liu, C., Yang, T., Li, X., Wei, L., Chen, D., Zhou, J., Yin, Y., Yu, X., & Li, F. (2020) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2020.111342 · Cited by 25 · see citing works

Simultaneous Quantification of Gallic Acid, Bergenin, Epicatechin, Epicatechin Gallate, Isoquercitrin, and Quercetin‐3‐Rhamnoside in Rat Plasma by LC‐MS/MS Method and Its Application to Pharmacokinetics after Oral Administration of Ardisia japonica Extract

Yu, X., Azietaku, J. T., Li, J., Wang, H., Zheng, F., Jia, H., & Chang, Y. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/4964291 · Cited by 24 · see citing works

An ultra high performance liquid chromatography with tandem mass spectrometry method for simultaneous determination of thirteen components extracted from Radix Puerariae in rat plasma and tissues: Application to pharmacokinetic and tissue distribution study

Wei, L., Zhu, P., Chen, X., Wang, Y., & Xu, Y. (2019) · Journal of Separation Science · doi:10.1002/jssc.201900824 · Cited by 22 · see citing works

Soyasaponins A 1 and A 2 exert anti-atherosclerotic functionalities by decreasing hypercholesterolemia and inflammation in high fat diet (HFD)-fed ApoE −/− mice

Xie, Q., Xiong, F., Wu, X., Chen, J., Gu, X., Su, C., Xiao, L., Zheng, Z., Wei, Y., Ullah, H., et al. (2019) · Food & Function · doi:10.1039/c9fo02654a · Cited by 22 · see citing works

Rosmarinic acid alleviates di-2-ethylhexyl phthalate (DEHP) -induced thyroid dysfunction via multiple inflammasomes activation

Wu, H., Ma, K., & Xiaolin, N. (2020) · The Journal of Toxicological Sciences · doi:10.2131/jts.45.373 · Cited by 22 · see citing works

Biotransformation of gallic acid by Beauveria sulfurescens ATCC 7159

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Oral Administration of the Japanese Traditional Medicine Keishibukuryogan-ka-yokuinin Decreases Reactive Oxygen Metabolites in Rat Plasma: Identification of Chemical Constituents Contributing to Antioxidant Activity

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Pits of Date Palm: Bioactive Composition, Antibacterial Activity and Antimutagenicity Potentials

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Gallic acid and hesperidin elevate neurotransmitters level and protect against oxidative stress, inflammation and apoptosis in aluminum chloride-induced Alzheimer's disease in rats

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Deriving high value products from depolymerized lignin oil, aided by (bio)catalytic funneling strategies

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Modification of cellulosic adsorbent via iron-based metal phenolic networks coating for efficient removal of chromium ion

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Novel insights on extraction and encapsulation techniques of elderberry bioactive compounds

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Development and Application of Whole-Cell Biosensors for the Detection of Gallic Acid

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Lignin Valorization: Production of High Value-Added Compounds by Engineered Microorganisms

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Biological Mechanisms and Related Natural Inhibitors of CD36 in Nonalcoholic Fatty Liver

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pH-sensitive gallol-rich chitosan hydrogel beads for on-off controlled drug delivery

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Recent advances in carrier-free natural small molecule self-assembly for drug delivery

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Phytochemicals Targeting JAK–STAT Pathways in Inflammatory Bowel Disease: Insights from Animal Models

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p‐Coumaric acid alleviates cisplatin‐induced ovarian toxicity in rats

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Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats

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Plant-Derived Bioactive Compounds: Exploring Neuroprotective, Metabolic, and Hepatoprotective Effects for Health Promotion and Disease Prevention

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Ultrasmall iron-gallic acid coordination polymer nanoparticles for scavenging ROS and suppressing inflammation in tauopathy-induced Alzheimer's disease

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Ameliorative Effects of Gallic Acid on Cisplatin‐Induced Nephrotoxicity in Rat Variations of Biochemistry, Histopathology, and Gene Expression

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Protection against Paraquat-Induced Oxidative Stress by Curcuma longa Extract-Loaded Polymeric Nanoparticles in Zebrafish Embryos

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Gallic acid impairs fructose-driven de novo lipogenesis and ameliorates hepatic steatosis via AMPK-dependent suppression of SREBP-1/ACC/FASN cascade

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Review of recent advances on health benefits, microbial transformations, and authenticity identification of Citri reticulatae Pericarpium bioactive compounds

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Tibetan medicine Ershiwuwei Lvxue Pill attenuates collagen-induced arthritis via inhibition of JAK2/STAT3 signaling pathway

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Functional nano drug delivery system with dual lubrication and immune escape for treating osteoarthritis

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Profiling of Phenolic Compounds and Triterpene Acids of Twelve Apple (Malus domestica Borkh.) Cultivars

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Biosynthesis of gallic acid fabricated tellurium nanoparticles (GA-Te NPs) for enhanced antibacterial, antioxidant, and cytotoxicity applications

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Development and validation of a UHPLC-ESI-MS/MS method for the simultaneous determination of organic acids and phenolic compounds in Filipendula vulgaris, Polygonum divaricatum, Hypericum linarioides, and Rheum ribes

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Construction of a colorimetric sensor array for the identification of phenolic compounds by the laccase-like activity of N-doped manganese oxide

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Polyphenol-sodium alginate supramolecular injectable hydrogel with antibacterial and anti-inflammatory capabilities for infected wound healing

Chen, Q., Yang, Z.-R., Du, S., Chen, S., Zhang, L., & Zhu, J. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.128636 · Cited by 34 · see citing works

Photothermal switch by gallic acid-calcium grafts synthesized by coordination chemistry for sequential treatment of bone tumor and regeneration

Hou, X., Zhang, L., Chen, Y., Liu, Z., Zhao, X., Lu, B., Luo, Y., Qu, X., Musskaya, O. N., Glazov, I. E., et al. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122724 · Cited by 34 · see citing works

Tapping into the natural aromatic potential of microbial lignin valorization towards aromatic fine chemicals

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Exploring the nutritional profiling and health benefits of Palmyra palm haustorium

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Ultrasound-Assisted Extraction of Antioxidants from Melastoma malabathricum Linn.: Modeling and Optimization Using Box–Behnken Design

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Rutin, a Flavonoid Compound Derived from Garlic, as a Potential Immunomodulatory and Anti-Inflammatory Agent against Murine Schistosomiasis mansoni

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Gallic acid suppresses the progression of triple-negative breast cancer HCC1806 cells via modulating PI3K/AKT/EGFR and MAPK signaling pathways

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Phenolic Acids-Mediated Regulation of Molecular Targets in Ovarian Cancer: Current Understanding and Future Perspectives

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Changes and metabolic mechanisms of organic acids in the fermentation of pu-erh tea

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Fractional extraction phenolics from C. oleifera seed kernels exhibited anti-inflammatory effect via PI3K/Akt/NF-κB signaling pathway under Caco-2/RAW264.7 co-culture cell model

Jin, C., Chu, C., Zhu, X., Lu, Y., Lu, Y., Yu, N., Jin, Y., & Meng, X. (2024) · Food Research International · doi:10.1016/j.foodres.2024.115268 · Cited by 32 · see citing works

Organic Functional Groups and Their Substitution Sites in Natural Flavonoids: A Review on Their Contributions to Antioxidant, Anti‐Inflammatory, and Analgesic Capabilities

An, J., Zhang, Z., Jin, A., Tan, M., Jiang, S., & Li, Y. (2025) · Food Science & Nutrition · doi:10.1002/fsn3.70191 · Cited by 32 · see citing works

Phytochemicals Targeting Ferroptosis: Therapeutic Opportunities and Prospects for Treating Breast Cancer

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β-Cyclodextrin/chitosan-based (polyvinyl alcohol-co-acrylic acid) interpenetrating hydrogels for oral drug delivery

Naeem, A., Yu, C., Hetonghui, Zhenzhong, Z., Weifeng, Z., & Yongmei, G. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125149 · Cited by 32 · see citing works

Gallic Acid Leads to Cell Death of Candida Albicans by the Apoptosis Mechanism

Liberato, I., Lino, L. A., Souza, J. K. D., Neto, J. B., Sá, L. G. D. A. V., Cabral, V. P. D. F., da Silva, C. R., Cavalcanti, B. C., de Moraes, M. O., Freire, V. N., et al. (2022) · Future Microbiology · doi:10.2217/fmb-2021-0139 · Cited by 31 · see citing works

Gallic acid attenuates LPS-induced inflammation in Caco-2 cells by suppressing the activation of the NF-κB/MAPK signaling pathway

Chu, C., Ru, H., Chen, Y., Xu, J., Wang, C., & Jin, Y. (2024) · Acta Biochimica et Biophysica Sinica · doi:10.3724/abbs.2024008 · Cited by 31 · see citing works

Exploring the Benefits of Nutrition of Little Millet: Unveiling the Effect of Processing Methods on Bioactive Properties

Kumari, A., Sadh, P. K., Kamboj, A., Yadav, B., Kumar, A., Sivakumar, S., Surekha, Saharan, B. S., Brar, B., Goyal, C., et al. (2025) · Journal of Food Biochemistry · doi:10.1155/jfbc/2488816 · Cited by 31 · see citing works

Recent advancement in prevention against hepatotoxicity, molecular mechanisms, and bioavailability of gallic acid, a natural phenolic compound: challenges and perspectives

Chen, P., Zou, F., & Liu, W. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1549526 · Cited by 22 · see citing works

The Evolving Therapeutic Landscape of Gallic Acid: A Review of Mechanistic Insights and Clinical Potential

Park, W. H. (2026) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.70491 · Cited by 2 · see citing works

Research Progress on Anti-Inflammatory Ef-fects of Gallic Acid

栾, 淞. (2022) · Advances in Clinical Medicine · doi:10.12677/acm.2022.127954 · Cited by 1 · see citing works

Unveiling the Therapeutic Potential of Gallic Acid: Mechanistic Insights into the Management of Pathogenesis: A Narrative Review

Alharbi, H. O. A., Sarwar, T., & Rahmani, A. H. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27031536 · Cited by 12 · see citing works

"Gallic Acid as a Multifunctional Bioactive Compound: From Molecular Mechanisms to Therapeutic Applications"

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