Who stays, who benefits? Predicting dropout and change in cognitive behaviour therapy for psychosis
Open accessAbstract
This study investigates the predictors of outcome in a secondary analysis of dropout and completer data from a randomized controlled effectiveness trial comparing CBTp to a wait-list group (Lincoln et al., 2012). Eighty patients with DSM-IV psychotic disorders seeking outpatient treatment were included. Predictors were assessed at baseline. Symptom outcome was assessed at post-treatment and at 1-year follow-up. The predictor×group interactions indicate that a longer duration of disorder predicted less improvement in negative symptoms in the CBTp but not in the wait-list group whereas jumping-to-conclusions was associated with poorer outcome only in the wait-list group. There were no CBTp specific predictors of improvement in positive symptoms. However, in the combined sample (immediate CBTp+the delayed CBTp group) baseline variables predicted significant amounts of positive and negative symptom variance at post-therapy and 1-year follow-up after controlling for pre-treatment symptoms. Lack of insight and low social functioning were the main predictors of drop-out, contributing to a prediction accuracy of 87%. The findings indicate that higher baseline symptom severity, poorer functioning, neurocognitive deficits, reasoning biases and comorbidity pose no barrier to improvement during CBTp. However, in line with previous predictor-research, the findings imply that patients need to receive treatment earlier.
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Lack of insight predicts drop out from cognitive behavior therapy and poorer therapeutic alliance.
“Studying interpersonal elements of treatment, Lincoln et al 37 reported that lack of insight predicted drop out from cognitive behavior therapy in patients with psychosis.”
From Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments (2018) · cites this paper as [37]
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Christensen, M. J., Vernal, D. L., Jeppesen, U. N., Hjorthøj, C. R., Mainz, J., Pinkham, A. E., Austin, S. F., Veling, W., Ward, T., Nordentoft, M., et al. (2026) · Psychological Medicine · doi:10.1017/s0033291726103870 · Cited by 3 · see citing works
Weijers, J., van Kaam, F. V., Selten, J., de Winter, R. D., & ten Kate, C. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1226507 · Cited by 3 · see citing works
Penzenstadler, L. E., Chatton, A., Huguelet, P., Lecardeur, L., Bartolomei, J., Brazo, P., Murys, E., Poupart, F., Rouvière, S., Saoud, M., et al. (2019) · Psychiatric Quarterly · doi:10.1007/s11126-019-09659-8 · Cited by 3 · see citing works
Trajectories of change within cognitive behavioral therapy for psychosis
Ludwig, L., Frantz, I., Bracker, J., Wittkamp, M. F., Jung, E., Wiesjahn, M., Grund, S., & Lincoln, T. M. (2025) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaf150 · Cited by 2 · see citing works
Self-citationRaman, S., & Richardson, T. H. (2019) · The Cognitive Behaviour Therapist · doi:10.1017/s1754470x19000151 · Cited by 2 · see citing works
Lincoln, T. M. (2016) · Elsevier eBooks · doi:10.1016/b978-3-437-22305-1.00007-7 · Cited by 2 · see citing works
Self-citationSudell, M., Smith, C. T., Liao, X., Longden, E., Dunn, G., Kendall, T., Emsley, R., Morrison, A. P., & Varese, F. (2021) · BMJ Open · doi:10.1136/bmjopen-2019-035062 · Cited by 2 · see citing works
Weijers, J., Debbané, M., ten Kate, C., van Kaam, F. V., de Winter, R. D., Eurelings-Bontekoe, E., & Selten, J. (2026) · Psychological Medicine · doi:10.1017/s0033291725102821 · Cited by 1 · see citing works
Rutter-Eley, E. L., Craig, T., Garety, P. A., Rus‐Calafell, M., Ball, H., Clancy, M., McDonnell, J., Gumley, A. I., Haddock, G., Bucci, S., et al. (2026) · JMIR Mental Health · doi:10.2196/77566 · Cited by 1 · see citing works
Verdaguer-Rodríguez, M., Comas, J. O., López‐Carrilero, R., Díaz-Cutraro, L., Espinosa, V., Ruiz‐Delgado, I., Barrigón, M. L., Grasa, E., Pousa, E., González‐Higueras, F., et al. (2026) · Archives of Women s Mental Health · doi:10.1007/s00737-025-01637-3 · Cited by 1 · see citing works
Seierstad, A., Schjøtt-Pedersen, O., Berentzen, L., Bull, H. C., Freeman, D. H., Gardsjord, E. S., Gjerstad, C. L., Lambe, S., Røssberg, J. I., & Lystad, J. U. (2026) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2026.2693804 · Cited by 1 · see citing works
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Update kognitive Verhaltenstherapie bei Psychosen
Pillny, M., & Lincoln, T. M. (2020) · Psychotherapie · doi:10.30820/2364-1517-2020-1-67 · Cited by 1 · see citing works
Self-citationComment utiliser les thérapies cognitives et comportementales ?
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Klingberg, S., & Hesse, K. (2018) · Der Nervenarzt
Lincoln, T. M. (2018) · Springer eBooks · doi:10.1007/978-3-662-54909-4_20
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Social kognition, psykoterapi og psykoselidelser
Graversen, A. (2019) · Psyke & Logos · doi:10.7146/pl.v40i2.117809
Lincoln, T. M. (2015) · Wiley eBooks · doi:10.1002/9781394259229.ch17
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Gorina, D., Piccolo, M. C. D., Georgiades, A., & Vieira, S. (2026) · Schizophrenia Research · doi:10.1016/j.schres.2026.08.018
- Authors
- Lincoln, T. M., Rief, W., Westermann, S., Ziegler, M., Kesting, M.-L., Heibach, E., & Mehl, S.
- Affiliations
- Universität Hamburg (DE)
- Philipps University of Marburg (DE)
- University of Bern (CH)
- Vitos (DE)
- Corresponding author
- Lincoln, Tania M.
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2014-05
- Volume
- 216
- Issue
- 2
- Pages
- 198-205
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2065530821
- Cited by
- 61
- References
- 62
- Citations by year
- 2026: 6 · 2025: 1 · 2024: 5 · 2023: 2 · 2022: 5 · 2021: 7 · 2020: 7 · 2019: 6 · 2018: 11 · 2017: 1 · 2016: 5 · 2015: 5
- FWCI
- 2.80
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- BORIS (University Library Bern) (submittedVersion, other-oa)
- Open Access CRIS of the University of Bern
- Funders
- Deutsche Forschungsgemeinschaft (LI 1298/3-1)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Keywords
- treatment discontinuation, predictors of treatment outcome, psychosis, negative symptoms, positive symptoms, jumping to conclusions, lack of insight, social functioning, treatment timing, comorbidities, neurocognitive impairment, reasoning biases, waitlist control
- MeSH terms
- Adult, Female, Forecasting, Humans, Male, Middle Aged, Patient Compliance, Patient Dropouts, Psychotic Disorders, Social Adjustment, Waiting Lists, Comorbidity, Cognitive Behavioral Therapy, Randomized Controlled Trials as Topic, Treatment Outcome, Young Adult
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