Cited by 719Schizophrenia research and treatmentMental Health Research TopicsMental Health and Psychiatry

Stress-reactivity in psychosis: Evidence for an affective pathway to psychosis

Myin-Germeys, Inez, van Os, Jim·2007·Clinical Psychology Review

Abstract

This paper will review a series of studies using the Experience Sampling Method that suggest that altered sensitivity to stress is an endophenotype for psychosis. The Experience Sampling Method is a structured diary technique allowing the assessment of emotional reactivity to stressors occurring in normal daily life. Elevated emotional reactivity to stress was found in subjects vulnerable to psychosis, suggesting that affective responses to stressors in the flow of daily life are an indicator of genetic and/or environmental liability to psychosis. Indeed, the small stressors in daily life associated with affective responses also predict more intense moment-to-moment variation of subtle positive psychotic experiences. Increased emotional reactivity was found to be independent from cognitive impairments, and argued to constitute evidence of an affective pathway to psychosis that may underlie a more episodic, reactive, good-outcome type of psychosis. Evidence for this hypothesis was found in data suggesting that the experience of stressful life events and early trauma were associated with increased stress-sensitivity, and that women were more likely to display elevated stress-reactivity. These findings are discussed in the light of recent biological and psychological mechanisms.

Integrity signals

Registry

Crossref · 10.1016/j.cpr.2006.09.005

Cites

145 of 145 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Myin-Germeys, I., & van Os, J.
Venue
Clinical Psychology Review
Publisher
Elsevier BV
Published
2007-05
Volume
27
Issue
4
Pages
409-424
ISSN
0272-7358 (ISSN-L)
OpenAlex
W2089854473
Cited by
719
References
145
Citations by year
2026: 26 · 2025: 53 · 2024: 44 · 2023: 52 · 2022: 39 · 2021: 40 · 2020: 38 · 2019: 26 · 2018: 37 · 2017: 50 · 2016: 45 · 2015: 38 · 2014: 43 · 2013: 37 · 2012: 35
FWCI
3.53
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Psychology Review (publishedVersion)
  • PubMed (publishedVersion)
  • Lirias (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
  • Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Keywords
stress reactivity, psychosis, endophenotypes, daily stress, life events, early trauma, sex differences, ecological momentary assessment
MeSH terms
Affect, Arousal, Female, Humans, Life Change Events, Male, Psychotic Disorders, Risk Factors, Sex Factors, Social Environment, Stress, Psychological, Genetic Predisposition to Disease

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review