Sleep disturbances in individuals at clinical high risk for psychosis
Open accessAbstract
There has been recent interest in understanding the role that sleep disturbance plays in patients at Clinical High Risk for psychosis (CHR). We assessed sleep disturbance in 194 CHR patients and 66 healthy control subjects and their relationship to symptoms (positive, negative and general functioning). Patients experienced significantly more sleep disturbance than healthy control subjects and their sleep disturbance was related to greater positive and negative symptoms and worse overall functioning. Targeting sleep disturbance in CHR individuals may provide alternative means of treating the CHR syndrome.
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Sleep disturbance is common among individuals at risk of psychosis.
“Sleep disturbance is common among individuals at risk of psychosis, yet few studies have investigated the relationship between sleep disturbance and clinical trajectory.”
From Sleep duration and psychotic experiences in patients at risk of psychosis: a secondary analysis of the EDIE-2 trial (2019) · cites this paper as Poe et al., 2017
Between 37% and 78% of individuals at risk of psychosis report sleep disturbance, as assessed on the Scale of Assessment of Positive Symptoms (SAPS).
“Between 37% and 78% of this population have been found to report sleep disturbance, as assessed on the Scale of Assessment of Positive Symptoms (SAPS) across several studies (Miller et al., 2003; Poe et al., 2017).”
From Sleep duration and psychotic experiences in patients at risk of psychosis: a secondary analysis of the EDIE-2 trial (2019) · cites this paper as Poe et al., 2017
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- Authors
- Poe, S.-L., Brucato, G., Bruno, N., Arndt, L. Y., Ben-David, S., Gill, K. E., Colibazzi, T., Kantrowitz, J. T., Corcoran, C. M., & Girgis, R. R.
- Affiliations
- Columbia University Irving Medical Center (US)
- Corresponding author
- Poe, Sarah-Lucy
- ORCID
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2017-03
- Volume
- 249
- Pages
- 240-243
- ISSN
- 0165-1781 (ISSN-L)
- PMC
- PMC5893278
- OpenAlex
- W2562375989
- Cited by
- 75
- References
- 15
- Citations by year
- 2026: 6 · 2025: 5 · 2024: 7 · 2023: 13 · 2022: 12 · 2021: 10 · 2020: 10 · 2019: 7 · 2018: 4 · 2017: 1
- FWCI
- 5.68
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Health (UL1 TR000040, 2KL2RR024157, K23MH066279, R21MH086125, R01P50 MH086385, R01 MH093398-01)
- Brain and Behavior Research Foundation
- Lieber Center for Schizophrenia Research
- New York State Office of Mental Hygiene (K23MH106746)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Keywords
- sleep disorders, clinical high risk for psychosis, psychosis, positive symptoms, negative symptoms, functioning
- MeSH terms
- Adolescent, Adult, Female, Humans, Male, Psychotic Disorders, Risk, Sleep Wake Disorders, Young Adult, Prodromal Symptoms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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