Prevalence and correlates of DSM-5 major depressive and related disorders in the community
Open accessAbstract
Although the DSM-5 has suggested the two new categories of Persistent Depressive Disorders (PDD) and Other Specified Depressive Disorders (OSDD), no study so far has applied the DSM-5 criteria throughout the range of depressive disorders. The aims of the present study were to 1) establish the lifetime prevalence of specific depressive disorders according to the new DSM-5 definitions in a community sample, and 2) determine their clinical relevance in terms of socio-demographic characteristics, comorbidity, course and treatment patterns. The semi-structured Diagnostic Interview for Genetic Studies was administered by masters-level psychologists to a random sample of an urban area (n=3720). The lifetime prevalence was 15.2% for PDD with persistent major depressive episode (MDE), 3.3% for PDD with pure dysthymia, 28.2% for Major Depressive Disorder (MDD) and 9.1% for OSDD. Subjects with PDD with persistent MDE were the most severely affected, followed by those with recurrent MDD, single episode MDD, PDD with pure dysthymia and OSDD and finally those without depressive disorders. Our data provide further evidence for the clinical significance of mild depressive disorders (OSDD), but cast doubt on the pertinence of lumping together PDD with persistent MDE and the former DSM-IV dysthymic disorder within the new PDD category.
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Up to 20-33% of depressive episodes at a point in time is associated with a history of bipolar spectrum disorder.
“up to 20-33% of depressive episodes at a point in time is associated with a history of bipolar spectrum disorder. 137”
From Time for united action on depression: a Lancet–World Psychiatric Association Commission (2022) · cites this paper as [137]
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- Authors
- Vandeleur, C. L., Fassassi, S., Castelao, E., Glaus, J., Strippoli, M.-P. F., Lasserre, A. M., Rudaz, D., Gebreab, S., Pistis, G., Aubry, J.-M., Angst, J., & Preisig, M.
- Affiliations
- Centre Hospitalier Universitaire Vaudois (CH)
- University Hospital of Geneva (CH)
- Psychiatrische Universitätsklinik Zürich (CH)
- Corresponding author
- Vandeleur, Caroline L.
- ORCID
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 2017-04
- Volume
- 250
- Pages
- 50-58
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2582718781
- Cited by
- 116
- References
- 41
- Citations by year
- 2026: 3 · 2025: 14 · 2024: 8 · 2023: 13 · 2022: 11 · 2021: 20 · 2020: 13 · 2019: 17 · 2018: 12 · 2017: 5
- FWCI
- 18.41
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Psychiatry Research (acceptedVersion)
- PubMed (publishedVersion)
- Archive ouverte UNIGE (University of Geneva) (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, cc-by-nc-nd)
- SERVAL (Université de Lausanne) (acceptedVersion, other-oa)
- IRIS (submittedVersion)
- Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion, cc-by-nc-nd)
- Zurich Open Repository and Archive (University of Zurich)
- Funders
- Swiss National Science Foundation (3200B0-105993, 3200B0-118308, 33CSCO-122661, 33CS30-139468 and 33CS30-148401, 323530-151479)
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- major depressive disorder, dysthymia, DSM-5, lifetime prevalence, comorbidities, depressive episode severity, treatment patterns, community sample, sociodemographic correlates
- MeSH terms
- Adult, Depression, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Recurrence, Comorbidity, Prevalence, Dysthymic Disorder, Diagnostic and Statistical Manual of Mental Disorders
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