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Preliminary evidence suggesting caution in the use of psychiatric self-report measures with adolescents with high-functioning autism spectrum disorders
Open accessAbstract
This study investigated the utility of self-report measures to screen for psychiatric comorbidities in autism spectrum disorders (ASDs). Thirty-eight 10-17 year olds with an ASD and without mental retardation completed: the Children's Depression Inventory-Short version (CDI-S), Revised Children's Manifest Anxiety Scale (RCMAS), Conners-Wells Adolescent Self-report Scale-Short edition (CASS-S), and Short Leyton Obsessional Inventory-Child Version (SLOI-CV). Their parents were interviewed with the Autism Comorbidity Interview-Present and Lifetime (ACI-PL) to establish psychiatric diagnoses. Sensitivity, specificity, positive and negative predictive values, and reliability coefficients were calculated for each self-report and compared to values from literature. The CDI-S and CASS-S yielded a high number of false negatives, with lower sensitivities and specificities in the sample than the literature. There was a nearly significant difference in total mean RCMAS scores between participants with and without anxiety, though again the means for both groups were below the threshold of concern. The SLOI-CV yielded a high false positive rate. All four instruments had reliability coefficients comparable to literature values. Results must be considered preliminary due to sample size. However, the findings suggest that although self-report instruments may provide useful information in the diagnosis of psychiatric comorbidities in ASD, caution must be exercised in their interpretation.
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“Consequently, researchers have often avoided attending to first‐person testimony, preferring to privilege reports from parents, teachers or other informants, or laboratory‐based observation over considering the perspectives of the person themselves (Jaswal & Akhtar, 2018; Mazefsky, Kao, & Oswald, 2011; McGeer, 2004; Milton, 2012).”
From Annual Research Review: Shifting from ‘normal science’ to neurodiversity in autism science (2022) · cites this paper as Mazefsky, Kao, & Oswald, 2011
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“First, alexithymia, or difficulty identifying, distinguishing, and describing emotions, has been well-documented in ASD.17,18,19”
From Emotion Regulation (2014) · cites this paper as [18]
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Metadata
- Authors
- Mazefsky, C. A., Kao, J., & Oswald, D. P.
- Affiliations
- University of Pittsburgh (US)
- Virginia Commonwealth University (US)
- Corresponding author
- Mazefsky, C.A.
- Venue
- Research in Autism Spectrum Disorders
- Publisher
- Elsevier BV
- Published
- 2011-01
- Volume
- 5
- Issue
- 1
- Pages
- 164-174
- ISSN
- 1878-0237 (ISSN-L)
- 1750-9467
- PMC
- PMC3762501
- OpenAlex
- W2077644735
- Cited by
- 325
- References
- 41
- Citations by year
- 2026: 10 · 2025: 19 · 2024: 30 · 2023: 11 · 2022: 24 · 2021: 28 · 2020: 30 · 2019: 20 · 2018: 17 · 2017: 26 · 2016: 14 · 2015: 25 · 2014: 23 · 2013: 23 · 2012: 10
- FWCI
- 9.28
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Research in Autism (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Organization for Autism Research
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (K23HD060601, L40 HD051318)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- autism spectrum disorder, high-functioning autism, adolescents, psychiatric comorbidity, self-report measures, depression screening, anxiety screening, obsessive-compulsive symptoms, Revised Children's Manifest Anxiety Scale, screening sensitivity and specificity, false positives and false negatives
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