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The Vitamin D Receptor: New Paradigms for the Regulation of Gene Expression by 1,25-Dihydroxyvitamin D3

Pike, J. Wesley, Meyer, Mark B.·2012·Rheumatic Disease Clinics of North America
DOI 10.1016/j.rdc.2012.03.004PMC PMC4448919
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  • 2276 genomic loci are occupied by the VDR, with 229 genes exhibiting altered expression profiles in response to vitamin D.

    “2276 genomic loci are occupied by the VDR with 229 genes exhibiting altered expression profiles in response to vitamin D.”

    From The evolution of human skin pigmentation: A changing medley of vitamins, genetic variability, and UV radiation during human expansion (2023) · cites this paper as Pike & Meyer, 2012

    The “Genome-wide Studies” section (page unavailable) says VDR binding at regulatory sites is frequently associated with changes in gene expression, supporting the general relationship. It does not report 2,276 occupied loci or 229 genes with altered expression; it says genome-wide studies of VDR binding were still in progress. (LLM, conf=0.84)

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Research works printed but not linked: 61

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Metadata

Authors
Pike, J. W., & Meyer, M. B.
Venue
Rheumatic Disease Clinics of North America
Publisher
Elsevier BV
Published
2012-02
Volume
38
Issue
1
Pages
13-27
ISSN
0889-857X
DOI
10.1016/j.rdc.2012.03.004
PMC
PMC4448919
Cited by
86
References
4
Language
en
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