The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Recent advances in natural polymer-based drug delivery systems
Abstract
Abstract Natural polymers have been extensively explored as the vehicles for encapsulation and delivery of drugs and other bioactive molecules, which have attracted tremendous attention. Their inherent advantages in marvelous biocompatibility, controlled enzyme degradation, specific interactions with some biomolecules, and easy modification endow them with versatility in drug delivery. In this perspective, the drug delivery systems (DDS) constructed by representative natural polymers, polysaccharides (chitosan and hyaluronic acid) and proteins (silk fibroin and collagen), are generally summarized. Payloads mainly involve small molecular weight drug, proteins, and DNA for the applications of tissue engineering, wound healing or anticancer therapy. Moreover, the DDS constructed by their derivatives and with other materials also have been presented focusing on the chemical and morphological modifications, the addtions of smart stimuli-triggered or targeted motifs and so on, which evidently promoted the delivery and therapy efficiency. Obviously, more intelligent and specific delivery strategies will be developed and more multifunctional natural polymers based carriers will be expended in the future. We try to seek more insights into the evolution of delivery system so as to figure out what we will truly gain in the next few decades to come.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Extracellular Matrix: Not Just Pretty Fibrils
Hynes, R. O. (2009) · Science · doi:10.1126/science.1176009 · Cited by 3,527
Chitosan-modifications and applications: Opportunities galore
Mourya, V. K., & Inamdar, N. N. (2008) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2008.03.002 · Cited by 1,150
Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation
Keselowsky, B. G., Collard, D. M., & García, A. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407356102 · Cited by 687
Crivelli, B., Bari, E., Perteghella, S., Catenacci, L., Sorrenti, M., Mocchi, M., Faragò, S., Tripodo, G., Prina-Mello, A., & Torre, M. L. (2019) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2019.02.008 · Cited by 141
Chen, J., Ouyang, J., Chen, Q., Deng, C., Meng, F., Zhang, J., Cheng, R., Lan, Q., & Zhong, Z. (2017) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.7b06879 · Cited by 124
Cited by
Polymeric Nanoparticles for Drug Delivery
Beach, M. A., Nayanathara, U., Gao, Y., Zhang, C., Xiong, Y., Wang, Y., & Such, G. K. (2024) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00705 · Cited by 1,155
Natural and Synthetic Polymers for Biomedical and Environmental Applications
Satchanska, G., Davidova, S., & Petrov, P. D. (2024) · Polymers · doi:10.3390/polym16081159 · Cited by 585
Recent trends in protein and peptide-based biomaterials for advanced drug delivery
Varanko, A., Saha, S., & Chilkoti, A. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.08.008 · Cited by 369
Pan, W., Qi, X., Xiang, Y., You, S., Cai, E., Gao, T., Tong, X., Hu, R., Shen, J., & Deng, H. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.12.007 · Cited by 266
Self-citationVasić, K., Knez, Ž., & Leitgeb, M. (2024) · Journal of Functional Biomaterials · doi:10.3390/jfb15080227 · Cited by 76
Advanced 3D-Printing Bioinks for Articular Cartilage Repair
Liang, Q., Ma, Y., Yao, X., & Wei, W. (2022) · International Journal of Bioprinting · doi:10.18063/ijb.v8i3.511 · Cited by 55
pH-sensitive hydrogel from Colocasia esculenta mucilage for controlled tramadol release
Noureen, S., Noreen, S., Ghumman, S. A., Batool, F., & Ahmed, N. (2025) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2025.103973 · Cited by 2
Metadata
- Authors
- Tong, X., Pan, W., Su, T., Zhang, M., Dong, W., & Qi, X.
- Venue
- Reactive and Functional Polymers
- Publisher
- Elsevier BV
- Published
- 2020-03
- Volume
- 148
- Pages
- 104501
- ISSN
- 1381-5148 (ISSN-L)
- OpenAlex
- W2999834265
- Cited by
- 349
- References
- 5
- FWCI
- 14.53
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
